Abstract: The present invention is a method for producing a nitrile from a primary amide, which is characterized by subjecting the primary amide to a dehydration reaction in a supercritical fluid in the presence of an acid catalyst. The present invention solves the problem of suppressing corrosion of a reaction apparatus and thermal decomposition of starting materials, while achieving the effect of improving the reaction rate and nitrile selectivity.
1. A method of producing a nitrile, the method comprising subjecting a primary
amide to a dehydration reaction in a supercritical fluid in the presence of an acid
5 catalyst.
2. The method according to claim 1, wherein said primary amide is a primary
amide comprising one or two primary amide groups.
10 3. The method according to claim 1 or 2, wherein said primary amide is a
saturated alkylamide, an unsaturated alkylamide, or an amide comprising an aromatic ring and/or a heterocyclic ring.
4. The method according to any one of claims 1 to 3, wherein said acid catalyst
15 is a solid acid catalyst.
5. The method according to any one of claims 1 to 4, wherein said supercritical
fluid is a supercritical fluid of one or more substances selected from the group
consisting of carbon dioxide, an alcohol compound, an ether compound and a
2 0 hydrocarbon compound.
6. The method according to any one of claims 1 to 5, wherein said supercritical
fluid is a supercritical fluid of one or more substances selected from the group
consisting of carbon dioxide, methanol, ethanol, 1-propanol, 2-propanol, 1-butanol,
2 5 2-butanol, isobutanol, tert-butanol, tert-amyl alcohol, diethyl ether, methyl-tert-butyl ether, diisopropyl ether, 1,2-dimethoxyethane, tetrahydrofuran, pentane, hexane and benzene.
| # | Name | Date |
|---|---|---|
| 1 | 202047036482-Correspondence Form-1 And POA_27-10-2021.pdf | 2021-10-27 |
| 1 | 202047036482-STATEMENT OF UNDERTAKING (FORM 3) [25-08-2020(online)].pdf | 2020-08-25 |
| 2 | 202047036482.pdf | 2021-10-18 |
| 2 | 202047036482-PROOF OF RIGHT [25-08-2020(online)].pdf | 2020-08-25 |
| 3 | 202047036482-PRIORITY DOCUMENTS [25-08-2020(online)].pdf | 2020-08-25 |
| 3 | 202047036482-FORM 3 [13-10-2020(online)].pdf | 2020-10-13 |
| 4 | 202047036482-FORM-26 [06-09-2020(online)].pdf | 2020-09-06 |
| 4 | 202047036482-FORM 1 [25-08-2020(online)].pdf | 2020-08-25 |
| 5 | 202047036482-DECLARATION OF INVENTORSHIP (FORM 5) [25-08-2020(online)].pdf | 2020-08-25 |
| 5 | 202047036482-AMMENDED DOCUMENTS [02-09-2020(online)].pdf | 2020-09-02 |
| 6 | 202047036482-COMPLETE SPECIFICATION [25-08-2020(online)].pdf | 2020-08-25 |
| 6 | 202047036482-Annexure [02-09-2020(online)].pdf | 2020-09-02 |
| 7 | 202047036482-RELEVANT DOCUMENTS [02-09-2020(online)].pdf | 2020-09-02 |
| 7 | 202047036482-FORM 13 [02-09-2020(online)].pdf | 2020-09-02 |
| 8 | 202047036482-MARKED COPIES OF AMENDEMENTS [02-09-2020(online)].pdf | 2020-09-02 |
| 9 | 202047036482-RELEVANT DOCUMENTS [02-09-2020(online)].pdf | 2020-09-02 |
| 9 | 202047036482-FORM 13 [02-09-2020(online)].pdf | 2020-09-02 |
| 10 | 202047036482-Annexure [02-09-2020(online)].pdf | 2020-09-02 |
| 10 | 202047036482-COMPLETE SPECIFICATION [25-08-2020(online)].pdf | 2020-08-25 |
| 11 | 202047036482-DECLARATION OF INVENTORSHIP (FORM 5) [25-08-2020(online)].pdf | 2020-08-25 |
| 11 | 202047036482-AMMENDED DOCUMENTS [02-09-2020(online)].pdf | 2020-09-02 |
| 12 | 202047036482-FORM-26 [06-09-2020(online)].pdf | 2020-09-06 |
| 12 | 202047036482-FORM 1 [25-08-2020(online)].pdf | 2020-08-25 |
| 13 | 202047036482-PRIORITY DOCUMENTS [25-08-2020(online)].pdf | 2020-08-25 |
| 13 | 202047036482-FORM 3 [13-10-2020(online)].pdf | 2020-10-13 |
| 14 | 202047036482.pdf | 2021-10-18 |
| 14 | 202047036482-PROOF OF RIGHT [25-08-2020(online)].pdf | 2020-08-25 |
| 15 | 202047036482-STATEMENT OF UNDERTAKING (FORM 3) [25-08-2020(online)].pdf | 2020-08-25 |
| 15 | 202047036482-Correspondence Form-1 And POA_27-10-2021.pdf | 2021-10-27 |