Method For Producing Peptide Compound, Protective Group Forming Reagent, And Substituted Benzyl Compound

Abstract: The present invention addresses the problem of providing a method for producing a peptide compound at a high yield, a reagent for forming a protective group at a high yield, and a novel substituted benzyl compound. The present invention provides a method for producing a peptide compound, said method comprising a step in which a substituted benzyl compound represented by formula (1) is used. In formula (1), Y represents -OH, -NHR, -SH or -X; R represents a hydrogen atom, an alkyl group, an arylalkyl group, a heteroarylalkyl group or a 9-fluorenylmethoxycarbonyl group; X represents Cl, Br or I; m represents 1 or 2; n represents an integer of 1-5; RBs independently represent an aliphatic hydrocarbon group; and RAs independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, and at least one of the aliphatic hydrocarbon groups has 12 or more carbon atoms. The benzene ring in formula (1) may further have a substituent in addition to RA.

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