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Methods And Formulations For Screening And Treatment Of Prostate Cancer
Abstract: The disclosure in various embodiments is related to a method of screening for risk of prostate cancer in humans comprising detecting the presence of mutations in AR androgen receptor gene (DHTR NR3C4) in a biological sample from said human and confirming cancer affliction or risk of cancer development in humans with such mutations. The disclosure also relates to a formulation for treating prostate cancer comprising a ligand of formula (I) and having cytotoxicity towards DU145 cell lines with CTC50 of at least 18 um/mL. Also disclosed are process for preparing a ligand for treating a human with prostate cancer and method of treating a human with prostate cancer having at least one genetic variation of rsl800053, rs9332969 or rs9332971.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
09 October 2015
Publication Number
15/2017
Publication Type
INA
Invention Field
MECHANICAL ENGINEERING
Status
Email
shankar@maxvalgroup.com
Parent Application
Patent Number
Legal Status
Grant Date
2022-02-18
Renewal Date
Applicants
Amrita Vishwa Vidyapeetham
Amrita Nagar, Coimbatore 641112, Tamil Nadu, India
Inventors
1. Dr. Prasanna RAMANI
Dhanvanthri Lab, Department of Sciences, Amrita Vishwa Vidyapeetham, Amrita Nagar, Coimbatore 641112, Tamil Nadu, India
2. Dr. Krishnan NAMBOORI P K
Computational Chemistry Research Group, Amrita Vishwa Vidyapeetham, Amrita Nagar, Coimbatore 641112, Tamil Nadu, India
Specification
Claims:See Attached , Description:See Attached
Documents
Orders
| Section | Controller | Decision Date |
|---|---|---|
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 5417-CHE-2015-IntimationOfGrant18-02-2022.pdf | 2022-02-18 |
| 1 | Form 5 [09-10-2015(online)].pdf | 2015-10-09 |
| 2 | Form 3 [09-10-2015(online)].pdf | 2015-10-09 |
| 2 | 5417-CHE-2015-PatentCertificate18-02-2022.pdf | 2022-02-18 |
| 3 | Drawing [09-10-2015(online)].pdf | 2015-10-09 |
| 3 | 5417-CHE-2015-FER.pdf | 2021-10-17 |
| 4 | Description(Complete) [09-10-2015(online)].pdf | 2015-10-09 |
| 4 | 5417-CHE-2015-US(14)-ExtendedHearingNotice-(HearingDate-23-08-2021).pdf | 2021-10-17 |
| 5 | abstract 5417-CHE-2015.jpg | 2015-11-14 |
| 5 | 5417-CHE-2015-US(14)-HearingNotice-(HearingDate-20-08-2021).pdf | 2021-10-17 |
| 6 | 5417-CHE-2015-Written submissions and relevant documents [25-08-2021(online)].pdf | 2021-08-25 |
| 6 | 5417-CHE-2015-Form 1-120216.pdf | 2016-06-30 |
| 7 | 5417-CHE-2015-Correspondence-F1-120216.pdf | 2016-06-30 |
| 7 | 5417-CHE-2015-Correspondence to notify the Controller [19-08-2021(online)].pdf | 2021-08-19 |
| 8 | 5417-CHE-2015-Power of Attorney-160316.pdf | 2016-07-11 |
| 8 | 5417-CHE-2015-Annexure [03-06-2021(online)].pdf | 2021-06-03 |
| 9 | 5417-CHE-2015-FORM 18 [22-10-2018(online)].pdf | 2018-10-22 |
| 9 | 5417-CHE-2015-CLAIMS [03-06-2021(online)].pdf | 2021-06-03 |
| 10 | 5417-CHE-2015-COMPLETE SPECIFICATION [03-06-2021(online)].pdf | 2021-06-03 |
| 10 | 5417-CHE-2015-OTHERS [03-06-2021(online)].pdf | 2021-06-03 |
| 11 | 5417-CHE-2015-CORRESPONDENCE [03-06-2021(online)].pdf | 2021-06-03 |
| 11 | 5417-CHE-2015-FER_SER_REPLY [03-06-2021(online)].pdf | 2021-06-03 |
| 12 | 5417-CHE-2015-DRAWING [03-06-2021(online)].pdf | 2021-06-03 |
| 13 | 5417-CHE-2015-CORRESPONDENCE [03-06-2021(online)].pdf | 2021-06-03 |
| 13 | 5417-CHE-2015-FER_SER_REPLY [03-06-2021(online)].pdf | 2021-06-03 |
| 14 | 5417-CHE-2015-COMPLETE SPECIFICATION [03-06-2021(online)].pdf | 2021-06-03 |
| 14 | 5417-CHE-2015-OTHERS [03-06-2021(online)].pdf | 2021-06-03 |
| 15 | 5417-CHE-2015-CLAIMS [03-06-2021(online)].pdf | 2021-06-03 |
| 15 | 5417-CHE-2015-FORM 18 [22-10-2018(online)].pdf | 2018-10-22 |
| 16 | 5417-CHE-2015-Annexure [03-06-2021(online)].pdf | 2021-06-03 |
| 16 | 5417-CHE-2015-Power of Attorney-160316.pdf | 2016-07-11 |
| 17 | 5417-CHE-2015-Correspondence to notify the Controller [19-08-2021(online)].pdf | 2021-08-19 |
| 17 | 5417-CHE-2015-Correspondence-F1-120216.pdf | 2016-06-30 |
| 18 | 5417-CHE-2015-Form 1-120216.pdf | 2016-06-30 |
| 18 | 5417-CHE-2015-Written submissions and relevant documents [25-08-2021(online)].pdf | 2021-08-25 |
| 19 | 5417-CHE-2015-US(14)-HearingNotice-(HearingDate-20-08-2021).pdf | 2021-10-17 |
| 19 | abstract 5417-CHE-2015.jpg | 2015-11-14 |
| 20 | Description(Complete) [09-10-2015(online)].pdf | 2015-10-09 |
| 20 | 5417-CHE-2015-US(14)-ExtendedHearingNotice-(HearingDate-23-08-2021).pdf | 2021-10-17 |
| 21 | Drawing [09-10-2015(online)].pdf | 2015-10-09 |
| 21 | 5417-CHE-2015-FER.pdf | 2021-10-17 |
| 22 | Form 3 [09-10-2015(online)].pdf | 2015-10-09 |
| 22 | 5417-CHE-2015-PatentCertificate18-02-2022.pdf | 2022-02-18 |
| 23 | Form 5 [09-10-2015(online)].pdf | 2015-10-09 |
| 23 | 5417-CHE-2015-IntimationOfGrant18-02-2022.pdf | 2022-02-18 |
Search Strategy
| 1 | SearchstrategyE_03-12-2020.pdf |