Abstract: The present disclosure provides in vitro methods for identifying the presence or absence of haemoglobin S (HbS) or haemoglobin C (HbC) in a blood sample, kits and devices thereof. The inventors have found that HbS shows a substantial decrease in absorption under deoxygenated conditions compared to oxygenated conditions. The inventors expect HbC to show a similar decrease in absorption under deoxygenated conditions compared to oxygenated conditions. The methods, kits and devices of the disclosure employ this decrease in absorption under deoxygenated conditions to identify the presence or absence of HbS or HbC in a blood sample. The methods, kits and devices of the present disclosure are simple, low cost, and provide a rapid way to identify the presence or absence of HbS or HbC in a blood sample in a point-of-care setting.
Claims:See attached , Description:See attached
| # | Name | Date |
|---|---|---|
| 1 | 202141009024-STATEMENT OF UNDERTAKING (FORM 3) [03-03-2021(online)].pdf | 2021-03-03 |
| 2 | 202141009024-POWER OF AUTHORITY [03-03-2021(online)].pdf | 2021-03-03 |
| 3 | 202141009024-FORM 1 [03-03-2021(online)].pdf | 2021-03-03 |
| 4 | 202141009024-DRAWINGS [03-03-2021(online)].pdf | 2021-03-03 |
| 5 | 202141009024-DECLARATION OF INVENTORSHIP (FORM 5) [03-03-2021(online)].pdf | 2021-03-03 |
| 6 | 202141009024-COMPLETE SPECIFICATION [03-03-2021(online)].pdf | 2021-03-03 |
| 7 | 202141009024-FORM 18 [08-03-2021(online)].pdf | 2021-03-08 |
| 8 | 202141009024-Proof of Right [04-08-2021(online)].pdf | 2021-08-04 |
| 9 | 202141009024-Power of Attorney [28-02-2022(online)].pdf | 2022-02-28 |
| 10 | 202141009024-Form 1 (Submitted on date of filing) [28-02-2022(online)].pdf | 2022-02-28 |
| 11 | 202141009024-EVIDENCE FOR REGISTRATION UNDER SSI [28-02-2022(online)].pdf | 2022-02-28 |
| 12 | 202141009024-EDUCATIONAL INSTITUTION(S) [28-02-2022(online)].pdf | 2022-02-28 |
| 13 | 202141009024-Covering Letter [28-02-2022(online)].pdf | 2022-02-28 |
| 14 | 202141009024-FORM 3 [22-03-2022(online)].pdf | 2022-03-22 |
| 15 | 202141009024-FORM-26 [12-09-2022(online)].pdf | 2022-09-12 |
| 16 | 202141009024-EVIDENCE FOR REGISTRATION UNDER SSI [12-09-2022(online)].pdf | 2022-09-12 |
| 17 | 202141009024-EDUCATIONAL INSTITUTION(S) [12-09-2022(online)].pdf | 2022-09-12 |
| 18 | 202141009024-CERTIFIED COPIES-CERTIFICATE U-S 72 147 & UR 133-2 [12-09-2022(online)].pdf | 2022-09-12 |
| 19 | 202141009024-FORM 18A [16-06-2023(online)].pdf | 2023-06-16 |
| 20 | 202141009024-EVIDENCE OF ELIGIBILTY RULE 24C1f [16-06-2023(online)].pdf | 2023-06-16 |
| 21 | 202141009024-FER.pdf | 2023-12-22 |
| 22 | 202141009024-FORM 3 [03-06-2024(online)].pdf | 2024-06-03 |
| 23 | 202141009024-FER_SER_REPLY [03-06-2024(online)].pdf | 2024-06-03 |
| 24 | 202141009024-CLAIMS [03-06-2024(online)].pdf | 2024-06-03 |
| 25 | 202141009024-US(14)-HearingNotice-(HearingDate-03-07-2024).pdf | 2024-06-21 |
| 26 | 202141009024-Correspondence to notify the Controller [28-06-2024(online)].pdf | 2024-06-28 |
| 27 | 202141009024-Written submissions and relevant documents [16-07-2024(online)].pdf | 2024-07-16 |
| 28 | 202141009024-Response to office action [23-07-2024(online)].pdf | 2024-07-23 |
| 29 | 202141009024-PatentCertificate24-07-2024.pdf | 2024-07-24 |
| 30 | 202141009024-IntimationOfGrant24-07-2024.pdf | 2024-07-24 |
| 31 | 202141009024- Certificate of Inventorship-044000182( 05-03-2025 ).pdf | 2025-03-05 |
| 32 | 202141009024- Certificate of Inventorship-044000181( 05-03-2025 ).pdf | 2025-03-05 |
| 33 | 202141009024- Certificate of Inventorship-044000180( 05-03-2025 ).pdf | 2025-03-05 |
| 1 | SEARCHSTRATEGYE_19-07-2023.pdf |
| 2 | SearchHistoryE_07-08-2023.pdf |