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Methods For Reducing Host Cell Protein Content In Antibody Purification Processes And Antibody Compositions Having Reduced Host Cell Protein Content

Abstract: The present disclosure relates to methods for reducing host cell protein content in antibody preparation recombinantly produced in a host cell in the manufacturing process of antibodies intended for administration to a patient. The disclosed methods may be performed in order to prepare therapeutic antibody preparations having reduced host cell protein.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
13 April 2023
Publication Number
47/2023
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

ELI LILLY AND COMPANY
LILLY CORPORATE CENTER Indianapolis, Indiana 46285

Inventors

1. BOWES, Brian David
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
2. KREBS, Lara Ellen
c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288
3. RICHER, Sarah M.
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, IN 46206-6288
4. HUANG, Lihua
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, IN 46206-6288
5. PLICHTA, Steven A.
c/o ELI LILLY AND COMPANY P.O. Box 6288 Indianapolis, IN 46206-6288

Specification

Documents

Application Documents

# Name Date
1 202317027267.pdf 2023-04-13
2 202317027267-STATEMENT OF UNDERTAKING (FORM 3) [13-04-2023(online)].pdf 2023-04-13
3 202317027267-Sequence Listing in txt [13-04-2023(online)].txt 2023-04-13
4 202317027267-Sequence Listing in PDF [13-04-2023(online)].pdf 2023-04-13
5 202317027267-REQUEST FOR EXAMINATION (FORM-18) [13-04-2023(online)].pdf 2023-04-13
6 202317027267-POWER OF AUTHORITY [13-04-2023(online)].pdf 2023-04-13
7 202317027267-FORM-26 [13-04-2023(online)].pdf 2023-04-13
8 202317027267-FORM 18 [13-04-2023(online)].pdf 2023-04-13
9 202317027267-FORM 1 [13-04-2023(online)].pdf 2023-04-13
10 202317027267-DECLARATION OF INVENTORSHIP (FORM 5) [13-04-2023(online)].pdf 2023-04-13
11 202317027267-COMPLETE SPECIFICATION [13-04-2023(online)].pdf 2023-04-13
12 202317027267-Proof of Right [11-10-2023(online)].pdf 2023-10-11
13 202317027267-FORM 3 [11-10-2023(online)].pdf 2023-10-11