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"Methods Of Treatment Utilizing Binding Proteins Of The Interleukin 21 Receptor"

Abstract: The present invention provides binding proteins and antigen-binding fragments thereof, including human antibodies, that specifically bind to the human interleukin-21 receptor (IL-21R), and methods of using them. The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing, treating, and/or preventing IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, and other immune system disorders.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
22 December 2010
Publication Number
09/2012
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

WYETH LLC
FIVE GIRALDA FARMS, MADISON, NEW JERSEY 07940, UNITED STATES OF AMERICA

Inventors

1. LAIRD BLOOM
82 FALCON STREET, NEEDHAM, MA 02492, U.S.A.
2. DAVINDER GILL
20 CHARLOTTE DRIVE, ANDOVER, MA 01810, USA
3. YULIA VUGMEYSTER
37 RIVERSIDE DRIVE, NORTH READING, MA 01864, USA
4. DEBORAH A. YOUNG
39 NELSON ROAD, MELROSE, MA 02176, USA
5. MARGOT O'TOOLE
353 ALBEMARLE ROAD, NEWTONVILLE, MA 02460, USA
6. HEATH M. GUAY
17 HUMBOLDT STREET, WALTHAM, MA 02452, USA
7. KARISSA K. ADKINS
31 TERSOLO ROAD, HAVERHILL, MA 01832, USA
8. AMY ARLENE WEAVER
1 FOREST STREET, NORTH READING, MA 01864, USA
9. SADHANA JAIN
18 FURBUSH ROAD, WEST ROXBURY, MA 02132, USA
10. MAYA ARAI
1070 BEACON STREET, APT. 3B, BROOKLINE, MA 02446, USA

Specification

Documents

Application Documents

# Name Date
1 Sequence listing-(22-12-2010).pdf 2010-12-22
2 9144-delnp-2010-GPA-(18-03-2011).pdf 2011-03-18
3 9144-delnp-2010-Correspondence-Others-(18-03-2011).pdf 2011-03-18
4 9144-delnp-2010-Form-1-(20-04-2011).pdf 2011-04-20
5 9144-delnp-2010-Correspondence-Others-(20-04-2011).pdf 2011-04-20
6 9144-DELNP-2010-Form-3-(20-05-2011).pdf 2011-05-20
7 9144-DELNP-2010-Correspondence-Others-(20-05-2011).pdf 2011-05-20
8 9144-delnp-2010-form-5.pdf 2011-08-20
9 9144-delnp-2010-form-3.pdf 2011-08-20
10 9144-delnp-2010-form-2.pdf 2011-08-20
11 9144-delnp-2010-form-1.pdf 2011-08-20
12 9144-delnp-2010-drawings.pdf 2011-08-20
13 9144-delnp-2010-description (complete).pdf 2011-08-20
14 9144-delnp-2010-correspondence-others.pdf 2011-08-20
15 9144-delnp-2010-claims.pdf 2011-08-20
16 9144-delnp-2010-abstract.pdf 2011-08-20
17 9144-delnp-2010-Form-3-(08-05-2012).pdf 2012-05-08
18 9144-delnp-2010-Correspondence Others-(08-05-2012).pdf 2012-05-08
19 9144-delnp-2010-Form-18-(15-05-2012).pdf 2012-05-15
20 9144-delnp-2010-Correspondence Others-(15-05-2012).pdf 2012-05-15
21 9144-DELNP-2010-FER.pdf 2017-03-29
22 9144-DELNP-2010-AbandonedLetter.pdf 2017-11-10

Search Strategy

1 searchstrategy_09-02-2017.pdf