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"Methods Of Treatment Utilizing Binding Proteins Of The Interleukin 21 Receptor"
Updated about 2 years ago
Abstract
The present invention provides binding proteins and antigen-binding fragments thereof, including human antibodies, that specifically bind to the human interleukin-21 receptor (IL-21R), and methods of using them. The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing, treating, and/or preventing IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, and other immune system disorders.
Information
| Application ID | 9144/DELNP/2010 |
| Invention Field | TRADITIONAL KNOWLEDGE BIOTECHNOLOGY |
| Date of Application | |
| Publication Number | 09/2012 |
Applicants
| Name | Address | Country | Nationality |
|---|---|---|---|
| WYETH LLC | FIVE GIRALDA FARMS, MADISON, NEW JERSEY 07940, UNITED STATES OF AMERICA | U.S.A. | U.S.A. |
Inventors
| Name | Address | Country | Nationality |
|---|---|---|---|
| LAIRD BLOOM | 82 FALCON STREET, NEEDHAM, MA 02492, U.S.A. | U.S.A. | U.S.A. |
| DAVINDER GILL | 20 CHARLOTTE DRIVE, ANDOVER, MA 01810, USA | U.S.A. | U.S.A. |
| YULIA VUGMEYSTER | 37 RIVERSIDE DRIVE, NORTH READING, MA 01864, USA | U.S.A. | U.S.A. |
| DEBORAH A. YOUNG | 39 NELSON ROAD, MELROSE, MA 02176, USA | U.S.A. | U.S.A. |
| MARGOT O'TOOLE | 353 ALBEMARLE ROAD, NEWTONVILLE, MA 02460, USA | U.S.A. | U.S.A. |
| HEATH M. GUAY | 17 HUMBOLDT STREET, WALTHAM, MA 02452, USA | U.S.A. | U.S.A. |
| KARISSA K. ADKINS | 31 TERSOLO ROAD, HAVERHILL, MA 01832, USA | U.S.A. | U.S.A. |
| AMY ARLENE WEAVER | 1 FOREST STREET, NORTH READING, MA 01864, USA | U.S.A. | U.S.A. |
| SADHANA JAIN | 18 FURBUSH ROAD, WEST ROXBURY, MA 02132, USA | U.S.A. | U.S.A. |
| MAYA ARAI | 1070 BEACON STREET, APT. 3B, BROOKLINE, MA 02446, USA | U.S.A. | U.S.A. |
Specification
Documents
| Name | Date |
| 9144-delnp-2010-Correspondence-Others-(18-03-2011).pdf | 2011-03-18 |
| 9144-delnp-2010-Correspondence-Others-(20-04-2011).pdf | 2011-04-20 |
| 9144-delnp-2010-GPA-(18-03-2011).pdf | 2011-03-18 |
| 9144-DELNP-2010-Correspondence-Others-(20-05-2011).pdf | 2011-05-20 |
| Sequence listing-(22-12-2010).pdf | 2010-12-22 |
| 9144-DELNP-2010-Form-3-(20-05-2011).pdf | 2011-05-20 |
| 9144-delnp-2010-Form-1-(20-04-2011).pdf | 2011-04-20 |
| 9144-delnp-2010-form-3.pdf | 2011-08-20 |
| 9144-delnp-2010-form-5.pdf | 2011-08-20 |
| 9144-delnp-2010-form-2.pdf | 2011-08-20 |
| 9144-delnp-2010-form-1.pdf | 2011-08-20 |
| 9144-delnp-2010-correspondence-others.pdf | 2011-08-20 |
| 9144-delnp-2010-abstract.pdf | 2011-08-20 |
| 9144-delnp-2010-Correspondence Others-(08-05-2012).pdf | 2012-05-08 |
| 9144-delnp-2010-Form-18-(15-05-2012).pdf | 2012-05-15 |
| 9144-delnp-2010-Correspondence Others-(15-05-2012).pdf | 2012-05-15 |
| 9144-delnp-2010-drawings.pdf | 2011-08-20 |
| 9144-delnp-2010-claims.pdf | 2011-08-20 |
| 9144-delnp-2010-Form-3-(08-05-2012).pdf | 2012-05-08 |
| 9144-DELNP-2010-FER.pdf | 2017-03-29 |
| 9144-DELNP-2010-AbandonedLetter.pdf | 2017-11-10 |
| 9144-delnp-2010-description (complete).pdf | 2011-08-20 |
Orders
| Applicant | Section | Controller | Decision Date | URL |