Abstract: The present invention provides binding proteins and antigen-binding fragments thereof, including human antibodies, that specifically bind to the human interleukin-21 receptor (IL-21R), and methods of using them. The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing, treating, and/or preventing IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, and other immune system disorders.
| # | Name | Date |
|---|---|---|
| 1 | Sequence listing-(22-12-2010).pdf | 2010-12-22 |
| 2 | 9144-delnp-2010-GPA-(18-03-2011).pdf | 2011-03-18 |
| 3 | 9144-delnp-2010-Correspondence-Others-(18-03-2011).pdf | 2011-03-18 |
| 4 | 9144-delnp-2010-Form-1-(20-04-2011).pdf | 2011-04-20 |
| 5 | 9144-delnp-2010-Correspondence-Others-(20-04-2011).pdf | 2011-04-20 |
| 6 | 9144-DELNP-2010-Form-3-(20-05-2011).pdf | 2011-05-20 |
| 7 | 9144-DELNP-2010-Correspondence-Others-(20-05-2011).pdf | 2011-05-20 |
| 8 | 9144-delnp-2010-form-5.pdf | 2011-08-20 |
| 9 | 9144-delnp-2010-form-3.pdf | 2011-08-20 |
| 10 | 9144-delnp-2010-form-2.pdf | 2011-08-20 |
| 11 | 9144-delnp-2010-form-1.pdf | 2011-08-20 |
| 12 | 9144-delnp-2010-drawings.pdf | 2011-08-20 |
| 13 | 9144-delnp-2010-description (complete).pdf | 2011-08-20 |
| 14 | 9144-delnp-2010-correspondence-others.pdf | 2011-08-20 |
| 15 | 9144-delnp-2010-claims.pdf | 2011-08-20 |
| 16 | 9144-delnp-2010-abstract.pdf | 2011-08-20 |
| 17 | 9144-delnp-2010-Form-3-(08-05-2012).pdf | 2012-05-08 |
| 18 | 9144-delnp-2010-Correspondence Others-(08-05-2012).pdf | 2012-05-08 |
| 19 | 9144-delnp-2010-Form-18-(15-05-2012).pdf | 2012-05-15 |
| 20 | 9144-delnp-2010-Correspondence Others-(15-05-2012).pdf | 2012-05-15 |
| 21 | 9144-DELNP-2010-FER.pdf | 2017-03-29 |
| 22 | 9144-DELNP-2010-AbandonedLetter.pdf | 2017-11-10 |
| 1 | searchstrategy_09-02-2017.pdf |