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Multisheet Multichannel Imaging Cytometry (Mmic) System
Abstract: MULTISHEET MULTICHANNEL IMAGING CYTOMETRY (MMIC) SYSTEM The present subject matter discloses a multisheet multichannel imaging cytometry (MMIC) system 100 based on vertical-aligned multi-sheet array (VAMSA) illumination technique. The MMIC system employs a unique combination of transmission grating 103, beam-expander 104, cylindrical lens 105, and objective system 106 in a specific optical configuration to generate a diffraction-limited illumination PSF (VAMSA-PSF). The detection is accomplished by a large field-of-view widefield 4f-system that consists of low NA objective lens 112, high performance fluorescence filters 114, tube lens 113 and a sensitive detector 115 (sCMOS/CCD/EMCCD). The VAMSA point spread function (PSF) enables in-parallel interrogation of specimens flowing simultaneously through multiple microfluidic channels 108. The very geometry of PSF enables high quality cross-sectional imaging, and facilitates volumetric interrogation of specimens flowing through microfluidic chip 107 consisting of multiple flow-channels, which is a step towards large population cell/organism screening.
Notices, Deadlines & Correspondence
Patent Information
Applicants
INDIAN INSTITUTE OF SCIENCE
Inventors
1. MONDAL, Partha Pratim
2. JOSHI, Prakash
Specification
DESC:MULTISHEET MULTICHANNEL IMAGING CYTOMETRY (MMIC) SYSTEM ,CLAIMS:AS ATTACHED
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202241030351-STATEMENT OF UNDERTAKING (FORM 3) [26-05-2022(online)].pdf | 2022-05-26 |
| 2 | 202241030351-PROVISIONAL SPECIFICATION [26-05-2022(online)].pdf | 2022-05-26 |
| 3 | 202241030351-POWER OF AUTHORITY [26-05-2022(online)].pdf | 2022-05-26 |
| 4 | 202241030351-FORM FOR SMALL ENTITY(FORM-28) [26-05-2022(online)].pdf | 2022-05-26 |
| 5 | 202241030351-FORM 1 [26-05-2022(online)].pdf | 2022-05-26 |
| 6 | 202241030351-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [26-05-2022(online)].pdf | 2022-05-26 |
| 7 | 202241030351-EDUCATIONAL INSTITUTION(S) [26-05-2022(online)].pdf | 2022-05-26 |
| 8 | 202241030351-DRAWINGS [26-05-2022(online)].pdf | 2022-05-26 |
| 9 | 202241030351-Proof of Right [17-10-2022(online)].pdf | 2022-10-17 |
| 10 | 202241030351-DRAWING [24-05-2023(online)].pdf | 2023-05-24 |
| 11 | 202241030351-CORRESPONDENCE-OTHERS [24-05-2023(online)].pdf | 2023-05-24 |
| 12 | 202241030351-COMPLETE SPECIFICATION [24-05-2023(online)].pdf | 2023-05-24 |
| 13 | 202241030351-FORM-9 [19-06-2023(online)].pdf | 2023-06-19 |
| 14 | 202241030351-FORM 18A [23-06-2023(online)].pdf | 2023-06-23 |
| 15 | 202241030351-EVIDENCE OF ELIGIBILTY RULE 24C1f [23-06-2023(online)].pdf | 2023-06-23 |
| 16 | 202241030351-FER.pdf | 2023-09-06 |
| 17 | 202241030351-FER_SER_REPLY [24-01-2024(online)].pdf | 2024-01-24 |
| 18 | 202241030351-CLAIMS [24-01-2024(online)].pdf | 2024-01-24 |
| 19 | 202241030351-FORM-8 [23-04-2024(online)].pdf | 2024-04-23 |
| 20 | 202241030351-Response to office action [24-09-2024(online)].pdf | 2024-09-24 |
| 21 | 202241030351-US(14)-HearingNotice-(HearingDate-05-03-2025).pdf | 2025-01-30 |
| 22 | 202241030351-Correspondence to notify the Controller [31-01-2025(online)].pdf | 2025-01-31 |
| 23 | 202241030351-FORM-26 [05-03-2025(online)].pdf | 2025-03-05 |
| 24 | 202241030351-Written submissions and relevant documents [19-03-2025(online)].pdf | 2025-03-19 |
| 25 | 202241030351-PatentCertificate18-08-2025.pdf | 2025-08-18 |
| 26 | 202241030351-IntimationOfGrant18-08-2025.pdf | 2025-08-18 |
| 27 | 202241030351-FORM 8A [14-10-2025(online)].pdf | 2025-10-14 |
| 28 | 202241030351-FORM 8A [14-10-2025(online)]-1.pdf | 2025-10-14 |
Search Strategy
| 1 | 20224103035(1)E_28-08-2023.pdf |