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New (Poly) Aminoalkylaminoalkylamide, Alkyl Urea, Or Alkyl Sulfonamide Derivatives Of Epipodophyllotoxin, A Process For Preparing Them, And Application Thereof In Therapy As Anticancer Agents

Abstract: The present invention relates to new derivatives of epipodophyllotoxin 4-substituted with an optionally substituted (poly)aminoalkylaminoalkylamidc, or alkyl-urea or alkyl- sulfonamide chain, a process for preparing them and their use as a medicine as an anticancer agent. Formula (1) wherein: - R represents hydrogen or C1-4alkyl, - A represents CO(CH2)n or CONH(CH2)n where n = 2, 3, 4, or 5, - R1 and R2 are as described herein.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
20 January 2011
Publication Number
05/2012
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

PIERRE FABRE MEDICAMENT
45, PLACE ABEL GANCE, F - 92100 BOULOGNE-BILLANCOURT, FRANCE,

Inventors

1. IMBERT, THIERRY
16, ROUTE DE SAIX - 81290 VIVIERS LES MONTAGNES, FRANCE,
2. GUMINSKI, YVES
17. RUE JACQUES PREVERT - 81090 LAGARRIGUE, FRANCE,
3. BARRET, JEAN-MARC
5, RUE DU TRESOR - 81100 CASTRES, FRANCE,
4. KRUCZYNSKI, ANNA
7 RESIDENCE CASTEL TROMPETTE - 31450 POMPERTUZAT, FRANCE,

Specification

Documents

Application Documents

# Name Date
1 483-DELNP-2011-AbandonedLetter.pdf 2017-04-15
1 483-DELNP-2011-GPA-(25-02-2011).pdf 2011-02-25
2 483-DELNP-2011-Correspondence-Others-(25-02-2011).pdf 2011-02-25
2 483-DELNP-2011_EXAMREPORT.pdf 2016-06-30
3 483-delnp-2011-Form-3-(01-07-2011).pdf 2011-07-01
3 483-delnp-2011-Correspondence-Others-(20-07-2012).pdf 2012-07-20
4 483-delnp-2011-Form-18-(20-07-2012).pdf 2012-07-20
4 483-delnp-2011-Correspondence Others-(01-07-2011).pdf 2011-07-01
5 483-DELNP-2011-Form-3-(29-07-2011).pdf 2011-07-29
5 483-delnp-2011-abstract.pdf 2011-08-21
6 483-DELNP-2011-Correspondence-Others-(29-07-2011).pdf 2011-07-29
6 483-delnp-2011-claims.pdf 2011-08-21
7 abstract.jpg 2011-08-21
7 483-delnp-2011-correspondence-others.pdf 2011-08-21
8 483-delnp-2011-form-5.pdf 2011-08-21
8 483-delnp-2011-description (complete).pdf 2011-08-21
9 483-delnp-2011-form-1.pdf 2011-08-21
9 483-delnp-2011-form-3.pdf 2011-08-21
10 483-delnp-2011-form-2.pdf 2011-08-21
11 483-delnp-2011-form-1.pdf 2011-08-21
11 483-delnp-2011-form-3.pdf 2011-08-21
12 483-delnp-2011-description (complete).pdf 2011-08-21
12 483-delnp-2011-form-5.pdf 2011-08-21
13 483-delnp-2011-correspondence-others.pdf 2011-08-21
13 abstract.jpg 2011-08-21
14 483-delnp-2011-claims.pdf 2011-08-21
14 483-DELNP-2011-Correspondence-Others-(29-07-2011).pdf 2011-07-29
15 483-delnp-2011-abstract.pdf 2011-08-21
15 483-DELNP-2011-Form-3-(29-07-2011).pdf 2011-07-29
16 483-delnp-2011-Correspondence Others-(01-07-2011).pdf 2011-07-01
16 483-delnp-2011-Form-18-(20-07-2012).pdf 2012-07-20
17 483-delnp-2011-Correspondence-Others-(20-07-2012).pdf 2012-07-20
17 483-delnp-2011-Form-3-(01-07-2011).pdf 2011-07-01
18 483-DELNP-2011-Correspondence-Others-(25-02-2011).pdf 2011-02-25
18 483-DELNP-2011_EXAMREPORT.pdf 2016-06-30
19 483-DELNP-2011-GPA-(25-02-2011).pdf 2011-02-25
19 483-DELNP-2011-AbandonedLetter.pdf 2017-04-15