Nitrogen Containing Heterocyclic Compound Salt Or Crystal Thereof

Nitrogen Containing Heterocyclic Compound Salt Or Crystal Thereof Pharmaceutical Composition And Flt3 Inhibitor

Abstract: The present invention addresses the problem of providing: a compound exhibiting excellent stability and/or solubility and the like and further improved FLT3 inhibitory activity; and a pharmaceutical composition. The present invention provides a salt or crystal of (S E) N (1 ((5 (2 ((4 cyanophenyl)amino) 4 (propylamino)pyrimidine 5 yl)pent 4 yne 1 yl)amino) 1 oxopropane 2 yl) 4 (dimethylamino) N methylbuto 2 enamide (compound A). This salt or crystal thereof exhibits excellent FLT3 inhibitory activity and excellent properties as a drug such as storage stability solubility or the like; hence said salt or crystal thereof is useful in treating a disease or a condition pertaining to FLT3. The present invention provides a pharmaceutical composition and an FLT3 inhibitor which contain this salt or the crystal thereof.

Patent Information

Application #

Filing Date

15 April 2016

Publication Number

36/2016

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

patent@depenning.com

Parent Application

Applicants

FUJIFILM CORPORATION

26 30 Nishiazabu 2 chome Minato ku Tokyo 1068620

Inventors

1. MIZUMOTO Shinsuke

c/o TOYAMA CHEMICAL CO. LTD. 4 1 Shimookui 2 chome Toyama shi Toyama 9308508

2. MATSUMOTO Takuya

c/o FUJIFILM CORPORATION 577 Ushijima Kaisei machi Ashigarakami gun Kanagawa 2588577

Specification

SOFT COPY ATTACHED IN PDF ONLY

Documents

Application Documents

#	Name	Date
1	Power of Attorney [15-04-2016(online)].pdf	2016-04-15
2	Form 5 [15-04-2016(online)].pdf	2016-04-15
3	Form 3 [15-04-2016(online)].pdf	2016-04-15
4	Form 18 [15-04-2016(online)].pdf	2016-04-15
5	Form 1 [15-04-2016(online)].pdf	2016-04-15
6	Drawing [15-04-2016(online)].pdf	2016-04-15
7	Description(Complete) [15-04-2016(online)].pdf	2016-04-15
8	201647013238.pdf	2016-06-08
9	201647013238-OTHERS-260416.pdf	2016-07-13
10	201647013238-Form 1-260416.pdf	2016-07-13
11	201647013238-Correspondence-260416.pdf	2016-07-13
12	Form 3 [07-10-2016(online)].pdf	2016-10-07
13	Form 3 [19-01-2017(online)].pdf	2017-01-19
14	201647013238-FER.pdf	2018-07-26
15	201647013238-AbandonedLetter.pdf	2019-01-30

Search Strategy

1	search_26-07-2018.pdf