FIELD OF INVENTION
The present invention relates to an herbal cream formulation useful for therapeutic and cosmetic
applications for the treatment of chronic skin disorder: Psoriasis. In the formulation of the
present invention, the two herb extract (Psoralia corylifolia and Pongamia pinnata)is used. It is
known to possess anti-inflammatory, antibacterial and antifungal activities. The herb along with
gel forming chemicals is used in the formulation and has been found to be very useful in treating
various skin infections causing depigmentation caused by fungal or bacterial reactions and
Psoriasis.
SUMMARY OF INVENTION
Accordingly, studies were undertaken to develop a cream base herbal formulation containing
herbal drug and synthetic ingredients for topical application over the affected areas which has
been found to help in curing Lht: disease psoriasis. This formulation has proven usellness in
removal of pigmentation on surface of the skin.
It was more effective and activated in presence of sunlight. Bakuchi (Psoralia coryli$olia) causes
irritation on the skin and it removes the upper layer of the skin and brings healthy skin by
improving the distribution of the melanin in the skin and cures this condition
OBJECTS OF THE INVENTION
The objective of the present invention is to provide an herbal formulation useful to treat chronic
skin disease, psoriasis and anti-scaling activity, which obviates the drawbacks of the present
formulations available in the market.
Accordingly, the present invention provides a herbal cream formulation useful for the treatment
of chronic skin diseases such as psoriasis, depigmentation and anti-fungal activity. This
comprises plant parts or oils from medicinal plants or any drug or their mixture thereof having
anti-inflammatory, high anti-fungal and antibacterial property like Psoralia corylifolia (bakuchi)
and karanj .
The extraction of bakuchi seedlkaranj seed powder was done using hexanelmethanol as solvent
in a soxhlet apparatus for 18hrs and then the extract was concentrated under vacuum at 50°C
separately. The oil extract of karanj from methanol solvent was re-extracted and the isolated
karanjin was recrystallized with methanol. Major constituent- Psoralen was used for the
treatment which was obtained as solid by evaporation of the solvent. The compound was
purified by recrystallization method fiom ethanol.
Accordingly, the present invention provides a herbal cream formulation useful for the treatment
of chronic skin diseases such as psoriasis, depigmentation and anti-fungal activity. This
comprises plant parts or oils from medicinal plants or any drug or their mixture thereof having
anti-inflammatory, high anti-fungal and antibacterial property like Psoralia corylifolia (bakuchi)
and karanj .
The extraction of bakuchi seedlkaranj seed powder was done using hexanelmethanol as solvent
in a soxhlet apparatus for 18hrs and then the extract was concentrated under vacuum at 50°C
separately. The oil extract of karanj from methanol solvent was re-extracted and the isolated
karanjin was recrystallized with methanol. Major constituent- Psoralen was used for the
treatment which was obtained as solid by evaporation of the solvent. The compound was
purified by recrystallization method fiom ethanol.
Method of preparation: Isolated Psoralen and karanjin was initially dispersed in a propylene
glycol and placed on shaker for complete mixing. Carbomer, Imid urea and water were heated in
vessel at 78 "C (phase A) and separately LLP (Light liquid paraffin), cetostearyl alcohol and
Stearic acid were heated in a separate vessel (phase B) at 78 "C and then the phase A and B are
mixed in homogenizer for'l hrs and finally the seed extract is mixed at 40 OC for the preparation
of final product.

We claim:
1. The herbal formulation prepared from isolates of Pongamia pinnata and Psoralia
corylifolia show excellent effect by reducing the thickness af epidermis.
2. The claiml product shows both have antibacterial and antipsoriatic activity.
3. The claiml product has been found to be very useful in treating various skin infections
causing depigrnentation caused by fungal or bacterial reactions and Psoriasis.
4. The claim 1 product an herbal formulation has been found to be useful to treat chronic
skin disease. anti-scaling activity.
5. The claim 1 product an herbal formulation has been found to be useful to for anti-scaling
activity of the skin.