Novel Glucocorticoid Receptor Agonists

Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen, -P(=O)(OH)2, or a pharmaceutically acceptable salt thereof, wherein the compound of Formula I, or pharmaceutically acceptable salt thereof is useful for treating autoimmune and inflammatory diseases, such as atopic dermatitis, rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, and inflammatory bowel disease.

Patent Information

Application #

Filing Date

26 August 2023

Publication Number

49/2023

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

ELI LILLY AND COMPANY

Lilly Corporate Center Indianapolis, Indiana 46285

Inventors

1. JAMISON, James Andrew

c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288

2. LEUNG, Donmienne Doen Mun

c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288

3. WURST, Jacqueline Mary

c/o Eli Lilly and Company P.O. Box 6288 Indianapolis, Indiana 46206-6288

Specification

Documents

Application Documents

#	Name	Date
1	202317057352-STATEMENT OF UNDERTAKING (FORM 3) [26-08-2023(online)].pdf	2023-08-26
2	202317057352-REQUEST FOR EXAMINATION (FORM-18) [26-08-2023(online)].pdf	2023-08-26
3	202317057352-POWER OF AUTHORITY [26-08-2023(online)].pdf	2023-08-26
4	202317057352-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [26-08-2023(online)].pdf	2023-08-26
5	202317057352-FORM 18 [26-08-2023(online)].pdf	2023-08-26
6	202317057352-FORM 1 [26-08-2023(online)].pdf	2023-08-26
7	202317057352-FIGURE OF ABSTRACT [26-08-2023(online)].pdf	2023-08-26
8	202317057352-DECLARATION OF INVENTORSHIP (FORM 5) [26-08-2023(online)].pdf	2023-08-26
9	202317057352-COMPLETE SPECIFICATION [26-08-2023(online)].pdf	2023-08-26
10	202317057352-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [26-08-2023(online)].pdf	2023-08-26
11	202317057352-Proof of Right [19-09-2023(online)].pdf	2023-09-19
12	202317057352-FORM 3 [06-02-2024(online)].pdf	2024-02-06
13	202317057352-FER.pdf	2025-07-18
14	202317057352-FORM 3 [22-08-2025(online)].pdf	2025-08-22
15	202317057352-Information under section 8(2) [29-08-2025(online)].pdf	2025-08-29

Search Strategy

1	202317057352_SearchStrategyNew_E_SearchStrategy202317057352E_17-07-2025.pdf