Novel Process For Preparation Of Venlafaxine Or Salt Thereof

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Novel Process For Preparation Of Venlafaxine Or Salt Thereof

Abstract: The present invention relates to a process for preparation of venlafaxine or salt thereof wherein the said process comprises of a) reducing cyano intermediate of Formula 2 with Raney Nickel KALCAT-8030 in presence of an ammoniacal alkanol to get the amine intermediate of Formula 4, b) N-methylating the amine intermediate of Formula 4 with aqueous formic acid and a source of formaldehyde, c) isolating venlafaxine or salt thereof from the reaction mass.

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Notices, Deadlines & Correspondence

Patent Information

Application #

Filing Date

28 February 2006

Publication Number

43/2007

Publication Type

INA

Invention Field

CHEMICAL

Status

Parent Application

Applicants

WOCKHARDT LIMITED

WOCKHARDT TOWERS, BANDRA-KURLA COMPLEX, BANDRA (EAST) MUMBAI 400 051,

Inventors

1. ANSARI SHAHID AKHTAR

N-3 CIDCO PLOT NO 428 NEAR GARDEN,AURANGABAD (M.S)

2. SAIYAD ANIS MUSHTAQE ALI

FLAT NO.04, SILVER HEIGHT APARTMENT, ANGURI BAGH AURANGABAD 431 210

3. MERWADE ARVIND YEKANATHSA

N-5 F-54 SHRINAGAR COLONY CIDCO AURANGABAD 431 003

4. MUKARRAM SIDDIQUI MOHAMMED JAWEED

H.NO 4-8-65 NAWABPURA NEAR NAGINA MASJID AURANGABAD 431 001