FIELD OF THE INVENTION
The invention is aimed to develop the natural organic fiber colored with the natural dye designed for enhancing a wearer's as colored cloth, while giving the wearer's a very natural appearance with therapeutic property with many other benefits used in colour therapy . Novel textiles for the prevention and treatment of Arthritis, rheumatic swelling is natural fiber which colored with natural dye; the invention comprises a natural colored organic natural fiber which includes an preventing and treating properties for Arthritis, rheumatic swelling, antinociceptive activity with the antimicrobial activity. Currently existing garments products, such as shirt, trousers, skirl, sari etc. are made from non coated fibers and do not include any bioactive coating agent applied topically to the fiber which capture and kill pathogenic microbes and have therapeutic effect by controlled release processes by the cloth media surface during normal use through the skin .However, till the date none of garments individually demonstrate a therapeutic effect by skin absorption and broad spectrum of activity against common pathogenic microbes. This is especially true in the case of garments made by synthetic fiber and colored by synthetic dye specially when the level of pathogen contamination during humid climate is relatively high and reaches to infectious levels.
Thus there is a need for novel textiles which is organic, colored and coated by accurate and specified medicinal plants describes in Ayurvedic text for specific therapeutic effect during normal use through the skin with antimicrobial properties.
BACKGROUND OF THE INVENTION
Ayurvedic treatment through skin exposure to fabrics dyed in medicinal herb dyes is very ancient technique for ayurvedic treatment as the skin received the medicinal benefits of these herbs through the exposure to clothing, bedding, or coir mats
When vastra exposed to skin, the herbs are absorbed into the body and function as a means of providing ayurvedic treatment for a broad range of diseases including Fever,Allergy and excessive heat and cold. It is also known to strengthen the immune system. Experimental research confirms that medicinal plant pigment dyeing of organic natural fiber helps in treating and preventing the rheumatic swelling
Novel textiles for treating and preventing the rheumatic disease, made from organic cotton, coloring and coating with different natural colour derived from various medicinal plants describes in ayurvedic text is the natural fiber which colored with natural dye.
Currently existing garments products, such as shirt, trousers, skirt, sari etc, are made from non coated fibers and do not include any bioactive coating agent applied topically to the fiber which have effect on rheumatic swelling by controlled release processes by the cloth media surface during normal use through the skin .However, till the date none of garments individually demonstrate a therapeutic effect by skin absorption on prevention and treatment of rheumatic disease .
SUMMARY OF THE INVENTION
In the present invention we have used Haldi (Curcuma longa) Methi (Trigonella foenum-graecum) - Saunth powder {Zingiber officinale ) Nirgundi {Vitex negundo) plant for the preparation of the fabric, coating of the fabric and dying of the fabric by most bioactive materials from above plants.
Our body can loses toxins and its metabolism can be enhanced by wearing the therapeutic clothing. Conventional Western medicine and traditional Eastern medicine recognize the skin as being the body's largest organ. The skin can act as a barrier but also as a conduit for outside substances to enter the body. Many environmental toxins and chemicals in conventional clothing are assimilated into the body through the skin. Anything which can improve the skin's natural ability to block and resist harmful chemicals and toxins from entering the body will be beneficial to health.
Ayurveda identifies seven unique layers of the skin where each layer has a distinct function. Starting from the outermost layer, the seven layers defined by Ayurveda are Avabhasini, Lohita, Shweta, Tamra. Vedini. Rohini and Mamsadhara.
The fourth layer. Tamra. supports the immune system and performs the function of acting as a barrier. Skin infections rellect an imbalance in this layer. The fabric of the present invention was improving the skin's ability to act as a barrier to external and environmental toxins: the wearer's health was improved.
Now that a connection has been established between exposure to intense sunlight and the skin, many people are protecting themselves against overexposure to the sun by using what are called sunscreen agents, which contain UV filters or absorbers. The UV absorbers or UV filters are organic substances which are able to absorb electromagnetic radiation in the UV range.
The skin is an efficient barrier to the penetration of water soluble substances, and the rate of transdermal pharmaceutical agent absorption is primarily determined by the agent's lipid solubility, water solubility, and polarity. Highly polar or water soluble pharmaceutical agents are effectively blocked by the skin. Even very lipophilic pharmaceutical agents penetrate the dermis very slowly compared with the rate of penetration across cell membranes
Penetration Enhancers", in Transdermal Delivery of Drugs, Vol. II, Kyodonieus et al.. Eds., CRC Press, Boca Raton, Fla. Few pharmaceutical agents fit this profile and those which do are not always predictably absorbed. Various forms of chemical enhancers, such as those enhancing lipophilicity, have been developed to improve transdermal transport when physically mixed with certain therapeutic agents and provide more predictable absorption.
Haldi (Curcuma longa) Methi (Trigonella foenum-graecum) - Saunth powder (Zingiber officinale ) Nirgundi (Vitex negundo)
Haldi (Curcuma longa) Family Zingiberaceae
Long trusted Turmeric the must have spice in every Indian home now finds itself in the limelight with western scientists raving about its potential uses to fight many tubborn inflammations and degenerative disorders thus vindicating the claims of seers as recorded in the ancient scripts of Ayurveda. According to a recent study conducted at the University of Arizona College of Medicine by Janet L. Funk, MD, working with Barbara N. Timmermann, PhD who prepared extracts of turmeric from the root of the plant on their own to test and compare with the commercially available products found that the extracts of turmeric with major cucurminoids was most effective in completely curbing the commencement of arthritis.
Dr Funk in a statement explained that this study paved the way for effective clinical application based on accurate information to prevent rheumatoid arthritis. The results of the study show that cucurminoids acts effectively in blocking the action of a protein that triggers of genes responsible for production of inflammatory proteins that cause degeneration of joints. It also showed effectiveness in blocking the pathway that affects bone loss associated with Osteoporosis.Turmeric may also be effective in tackling other inflammatory disorders like asthma, multiple sclerosis and inflammatory bowel disorders.The article, 'Efficacy and Mechanism of Action of Turmeric Supplements in the Treatment of Experimental Arthritisis available in the online issue of proteins and Rheumatism published on Oct. 30, 2006. Turmeric Extracts Containing Curcuminoids Prevent Experimental Rheumatoid Arthritis# ... Turmeric has been used for centuries in Ayurvedic medicine as a treatment for inflammatory disorders including arthritis. ... Because pretreatment was required to prevent joint inflammation, these data support the use of curcuminoid-containing turmeric products only for arthritis prevention and not for disease treatment in the face of active inflammation. Turmeric has been used for centuries in Ayurvedic medicine as a treatment for inflammatory disorders including arthritis. On the basis of this traditional usage, dietary supplements containing turmeric rhizome and turmeric extracts are also being used in the western world for arthritis treatment and prevention. However, to our knowledge, no data are available regarding antiarthritic efficacy of complex turmeric extracts similar in composition to those available for use as dietary supplements. Therefore, the studies described here were undertaken to determine the in vivo efficacy of well-characterized curcuminoid-containing turmeric extracts in the prevention or treatment of arthritis using streptococcal cell wall (SCW)-induced arthritis, a well-described animal model of rheumatoid arthritis (RA). Arthritic index, a clinical measure of joint swelling, was used as the primary endpoint for assessing the effect of extracts
on joint inflammation. An essential oil-depleted turmeric fraction containing 41% of the three major curcuminoids was efficacious in preventing joint inflammation when treatment was started before, but not after, the onset of joint inflammation. A commercial sample containing 94% of the three major curcuminoids was more potent in preventing arthritis than the essential oil-depleted turmeric fraction when compared by total curcuminoid dose per body weight. In conclusion, these data (1) document the in vivo antiarthritic efficacy of an essential oil-depleted turmeric fraction and (2) suggest that the three major curcuminoids are responsible for this antiarthritic effect, while the remaining compounds in the crude turmeric extract may inhibit this protective effect.
Methi Eng. - Fenugreek (Trigonella foenum-graecum) Family Fabaceae.
Saunth powder {Zingiber officinale) Family (Zingiberaceae). Saunth powder
is similar to other preparations also known as HMP-33, Zingiber officinale, and gingeroles. This preparation has been marketed to the general population and to some ACR members as a "nutriceutical" that may promote "joint health" in osteoarthritis, studies have shown some evidence that ginger may reduce prostaglandin and leukotriene production in vitro. There is no published data to suggest if this compound affects COX-1 or COX-2 preferentially. In one small study, ginger oil was given to treat adjuvant arthritis in rats and a significant reduction in paw joint swelling was observed. A multicenter, controlled clinical trial of ginger extract in humans with osteoarthritis of the knee is in progress.Ginger is extracted from the rhizomes of the ginger root (Zingiberis rhixoma) that is grown worldwide, including China and Africa. In addition to its use as a spice, ginger has a long history of use in traditional Chinese medicine for the treatment of dyspepsia, motion sickness, nausea and for the relief of pain and inflammation associated with "rheumatism." The mechanisms underlying the
antiemetic effects of ginger are uncertain. Ginger extract preparations vary widely in their concentration and purity, depending on the source of the root, extraction methodology and formulation.
Nirgundi (Vitex negundo) Family Family verbenaceae The Sanskrit word nirgundi literally means that which protects the body from diseases. It is one of the herbs mentioned in all Samhitas of Ayurveda and has varios synonyms like sinduka, sephali, sitabhiru, vanaka, bhutakesi, anilamanjiri etc. Two varieties of nirgundi described in Nighantus are white flowered sinduvaraka and blue flowered - suvaha (Bhavaprakasa). The great sage Caraka has categorized nirgundi as krmighna anthelmintic and visaghna - anti - toxin. The plant grows all over India, in wastelands, upto 1500 meters elevation. Commonly it is cultivated as a hedge plant. A large shrub or rather small tree grows 2-4 meters in height, with quadrangular branches and thin grey bark. The leaves petiolate, smooth, exstipulate, have a typical pungent odor. The flowers are bluish purple in color, lanceolate, in panicles upto 30 cm long. The fruits are ovoid or obovoid, four-seeded drupes, black when ripe. The botanical name of nirgundi is Vitex negundo and it belongs to family verbenaceae. The leaves contain fragrant, volatile oil and resins. The fruits contain resine, astringent organic acids, alkaloids and a pigment. The plant also contains alkaloids, glycosides, flavonoids, reducing sugars, sterols, resin and tannins. From seeds-n-triacontane, n-hentriacontane, n-pentatriacontane. n-nonacosane, sitosterol, p-hydrobenzoic acid and 5- oxyisophthalic acid isolated. Also. 3, 4- dihydroxybenzoec acid is isolated from seeds. Vanillic acid, p-hydroxybenzoic acid and luteolin are isolated from bark. From essential oil pinene, limonene, camphene, phellandrene, methylheptanone, cumene, linalool, camphor, 4-terpineol, citral, caryophylline oxide, caryophyllene, terpinyl acetate, benzal - dehyde & cinnamaldehyde identified. Nishinaside and regundiside isolated from leaves

Externally, nirgundi decoction is used for steam bath for arthritis, joint pains and sciatica. Particularly, nirgundi is very effective in alleviating the low back pain. The dried leaves when smoked are said to relieve catarrh and headache. Oil prepared with the juice is applied to sinuses and scrofulous sores. Oil is used also as bathing oil for rubbing on the head and in cervical lymphadenitis. The oil is also found to be salutary for sloughing wounds and ulcers. In premature graying of hair and scalp infections like pediculosis and lice, the oil is applied with great benefit. Decoction of nirgundi leaves is an effective gargle in stomatitis and sore throat. The poultice of hot leaves applied on swollen and painful joints, effectively mitigates the pains. Medicated oil is beneficial in suppurative otitis. The tub-bath of the decoction of its leaves is rewarding in sciatica, epididymo-orchitis and uterine inflammations.
Example
Preparation of bioactive material from plants
1. Collection of the parts of the plants (leaves, barks, stems, flowers, fruits,
seeds).
2. Tested for the raw material for assessment of colour contents,
Extraction
The bioactive material extraction is broadly divided into extraction method &
extraction technology.
Aqueous Method:
Boil known amount plant stuff in 100 ml. of soft water at 100 C.
Filter the dye solution
Record the optical density
Alkaline Method:

Prepare 1% alkaline solution with addition of 1 g. Socium carbonate/Sodium
hydroxide in 100 ml. of water.
Enter the dye material and boil at 100 C.
Filter the dye solution
Record the optical density
Acidic Method
Prepare 1% of acidic solution by adding 1 ml. of HCL in 100 ml. of Soft water.
Enter the dye material and boil at 100 C.
Filter the dye solution
Record the optical density
Alcoholic Method
Add 50 ml. of alcohol to 50 ml. of water
Enter the dye material and boil
Filter the dye solution
We used the commen Extraction Technology such as Super Critical Fluid and Microwave Assisted Extraction Technology
According to the objective of the invention the process for making the fabric of the present invention entails steps which are substantially similar to current conventional processes for producing cotton, with the exception that the wood raw material used in the process of the present invention is a bioactive material from Haldi (Curcuma longa) Methi (Trigonella foenum-graecum) - Saunth powder (Zingiber officinale ) Nirgundi (Vitex negundo)
In the present invention textiles was formed by weaving, knitting, crocheting,
knotting of Haldi (Curcuma longa) Methi (Trigonella foenum-graecum) -
Saunth powder (Zingiber officinale ) Nirgundi (Vitex negundo) plant fibers
pressing together.
Before the spinning step, the wood pulp was mixed with cotton fibers. A preferred mixture is one in which the different fibers exist in a proportionate ratio of 20%-25% Haldi (Curcuma longa) Methi (Trigonella foenum-graecum) - Saunth powder (Zingiber officinale ) Nirgundi (Vitex negundo) fibers and 80% cotton fibers.
The fibers produced by the present invention have high strength, especially when wet, and good dimensional stabillity and firmness. In addition, the fibers produced by the process of the invention are highly absorbent
The fibers which result from the process of the present invention will be used in the manufacture of clothing, as medical fabrics.
Coating is a common technique used to apply dye particles onto textiles. The coating compositions that can modify the surface of textiles are usually composed of micro-particles, a surfactant, ingredients and a carrier medium. Several methods can apply coating onto fabrics, including spraying, transfer printing, washing, rinsing and padding. Of these methods, padding is the most commonly used. The nano-particles are attached to the fabrics with the use of a padder adjusted to suitable pressure and speed, followed by drying and curing.
Coating enhance and extend the range of functional performance properties of textiles and the use of this techniques is growing rapidly as the applications for technical textiles become more diverse. Coating is a process in which a polymeric layer is applied directly to one or both surfaces of the fabric
• Coating can mostly be used of products which having capacity to convert in viscose liquid form. This viscose liquid so easily can spread over the surface and form coating.
• Drying or curing process which hardens the coating to produce a non blocking product.
• Due to viscosity requirement it is limited to linear polymers, which can be coated as a polymer melt or solution and on cooling, form a solid film or form solid film on evaporation of the solvent.
• There are some types of coatings that can be applied in the liquid form and then chemically cross-linked to form a solid-film.
Bioactive functional material from plant Haldi (Curcuma longa) Methi (Trigonella foenum-graecum) - Saunth powder {Zingiber officinale ) Nirgundi (Vitex negundo) was coated as per heavy-duty technical textile coating 700 gm bioactive functional material was applied onto the fabric
Three layers of bioactive functional material Haldi (Curcuma longa) Methi (Trigonella foenum-graecum) - Saunth powder {Zingiber officinale ) Nirgundi {Vitex negundo) was applied onto the fabric. The patches of the bioactive functional material were also applied in seven layers at specific area of the garment.
In the present invention we developed a nano-scale processing technology that allows molecular arrangement and molecular self-assembly necessary to bring out further advanced functionalities in textile processing than the existing dyeing processing.
Natural dyes obtained from the root bark and flowers of the bioactive functional material has pale to yellow color , has good stability, minimal aroma, and does not contain any organic solvent residuals is provided.
In our study, Natural dyes from various medicinal plants has applied to 100% organic cotton fabric , 100% silk and wool to develop a fabric, which is specific for the prevention and treatment of specific disease. In order to optimize the process parameter, cotton fabric was treated with Natural dyes at various concentrations that is 1, 2, 3 and 5 gpl at 60°C for 30 min by pad-dry -cure method. Many solvents have been used for extraction of natural dyes from various plants according to the chemical property of the natural dye. The finished fabric samples have been tested for the specific activity related with the disease by in-vitro trials. The natural dye treated fabrics was exhibited significant decrees in the signs and symptoms of specific disease with antimicrobial activity against the Staphylococcus aureus (ATCC 6538). The treated cotton fabrics have shown excellent effect on the reduction of pain and swelling in Arthritis, rheumatic affected patient with antimicrobial activity at 5 gpl concentration. The wash durability of the treated sample was found good even after 50 wash. Every dyed garment has its rubbing fastness irrespective of its origin. The beneficial aspects of the medicinal plant dyes in comparison to any of the synthetic dyes are high. Chemically created colors are terrible poisons. The present invention aims at developing an eco friendly textiles which is organic and 100 % natural, which colored and coated by accurate and specified medicinal plants describes in Ayurvedic text for various textile applications. Some selective species of medicinal plants were identified and screened for their activity and the extracts were applied to cotton fabrics. When cloths come into the contact of skin it rubbing the sweat glands during normal use and effect of the human body. An extensive study was conducted to assess the therapeutic effectiveness of the herbs
by employing standard test methods and the findings were discussed in this invention.
Description of the invention for the Various methods of extraction for obtaining the active principles and desired colors for dyeing.
The basic raw materials were required for manufacturing of vegetable dyes was the natural produce and requires following steps for manufacturing of vegetable dyes.
3. Collected the Curcuma longa, Colchicum luteutn, Withania somnifera, Vitex-negundo and Trigonella foenum-graecum (leaves, barks, stems, flowers, fruits, seeds).
4. Tested the raw material for assessment of colour contents by HPLC and HPTLC,
5. Dyeing.
6. Size reduction by pulverizing
7. Separation of different size by vibrating screen,
8. Extraction of colouring component
9. Phase separation
10. Fine filtering
11. Drying of coloring matter (Dyes) in spray dryer,
12. Packing:
The extraction methods of vegetable dyes basically depend on medium in which
the dye is extracted. There are mainly four methods used in extraction of natural
dyes.
Aqueous Method:
We Boils the specific amount of dyestuff in 100 ml. of soft water at 50- 100 C.
Filter the dye solution
Record the optical density
Alkaline Method:
Prepare 1% alkaline solution with addition of 1 g. Socium carbonate/Sodium
hydroxide in 100 ml. of water.
Enter the dye material and boil at 100 C.
Filter the dye solution
Record the optical density
Acidic Method
Prepare 1% of acidic solution by adding 1 ml. of HCL in 100 ml. of Soft water.
Enter the dye material and boil at 100 C.
Filter the dye solution
Record the optical density
Alcoholic Method
Add 50 ml. of alcohol to 50 ml. of water
Enter the dye material and boil
Filter the dye solution
Solvent Extraction
Super Critical Fluid Extraction is a further advancement making significant step over the use of conventional solvent extraction technology. We used CO2 as extraction media. It was non-hazardous and subject to minimum waste generation.
Microwave Assisted Extraction Technology
The Microwave Assisted Extraction Technology was used for high-speed method for the extraction of selectively targeted compounds.
Continuous Steam Distillation Process:
The process consists of a totally insulated pneumatic conveying system using super heated steam as a carrier gas.
Some embodiments of the invention have been described above, and in addition, some specific details are shown for purposes of illustrating the inventive principles. However, numerous other arrangements may be devised in accordance with the inventive principles of this patent disclosure. Further, well known processes have not been described in detail in order not to obscure the invention. Thus, while the invention is described in conjunction with the specific embodiments described above, it is not limited to these embodiments or drawings. Rather, the invention is intended to cover alternatives, modifications, and equivalents that come within the scope and spirit of the inventive principles set out above.

What it claimed is:
1. A therapeutic eco friendly textiles comprising an 100% Organic cotton, silk and wool fabric whose dye and coated with natural colour which have selective therapeutic property for the prevention and treatment of Arthritis.
2. The therapeutic eco friendly textiles and clothing claim 1 where the fabric is selected from the clothing that is made from materials that was grown without the use of synthetic chemicals such as pesticides - herbicides or other chemicals.
3. The therapeutic eco friendly textiles and clothing of claim 2 where the fabric is 100% cotton, silk and wool.
4. The therapeutic eco friendly textiles and clothing claim 1 where the first therapeutic agent for the prevention and treatment of Arthritis and rheumatic swelling is the natural colour and active principles obtained from the rhizomes of the different species of Zingiberaceae family, which includes Curcuma longa.
5. The therapeutic eco friendly textiles and clothing claim 4 where the second therapeutic agent for the prevention and treatment of Arthritis and rheumatic swelling is the natural colour and other active ingredient obtained from the rhizomes and other parts of the Colchicum luteum from Colclticaceae family.
6. The therapeutic eco friendly textiles and clothing claim 5 where the third therapeutic agent for the prevention and treatment of Arthritis and rheumatic swelling is the natural colour and other active ingredient obtained specifically from the rhizomes of the Withania somnifera, also known as Ashwagandha, Indian ginseng from family, Solanaceae.
7. The therapeutic eco friendly textiles and clothing claim 6 where the fourth therapeutic agent for the prevention and treatment of Arthritis and rheumatic swelling and for antinociceptive effect is the natural colour and other active ingredient obtained from the leaves and other parts of the Vitex negundo , also known as Nirgundi from family, Lamiaceae.
8. The therapeutic eco friendly textiles and clothing claim 7 where the fifth therapeutic agent for the prevention and treatment of Arthritis and rheumatic swelling and for antinociceptive effect is the natural colour and other active ingredient obtained from the seeds and other parts of the Trigonella foenum-graecum , also known as Fenugreek from family, Fabaceae.
9. The therapeutic eco friendly textiles and clothing claim 8 where the sixth
therapeutic agent for the prevention and treatment of Arthritis and
rheumatic swelling is the natural colour and other active ingredient obtained
from rhizomes of the Zanzibar officinalis, also known as Ginger from family,
Zingiberaceae
10. The eco friendly textiles and clothing of claim 1 where the entire
ingredient claimed as therapeutic agent for the dyeing of organic fiber and
cloths was tested for their efficacy by various in-vivo and in-vitro clinical trail
the results was very significant on prevention and treatment of Arthritis
,rheumatic swelling and also exhibits the antinociceptive effect.
11. The in-vivo and in-vitro clinical trail claim 10 where the tail flick test in rats and acetic acid induced writhing in mice were used for measuring the antinociceptive activity of ingredient claimed as antinociceptive.
12. A method for making an therapeutic aprons comprising a eco friendly textiles and clothing, dye and treated with an natural colors and other active ingredients from the various parts of the plant Curcuma longa, Colchicum luteum, Withania somnifera, Vitex-negundo and Trigonella foenum-graecum .
14. The method of claim 12 where the eco friendly textiles fabric is 100%
organic cotton, silk and wool.
15. In the method for making an therapeutic, eco friendly textiles and
clothing use of all pre, post and simultaneous mordanting was used for the
changing of the colour of same dyestuff. Thus the different colour tones were
possible with single mordant or combination of mordants.
16. In the method for coloring the therapeutic, eco friendly textiles and
clothing salt (1:8) and vinegar (4:1) ratio in cold water was used as colour
fixative on the fabric with simmering upto one hour.
17. The eco friendly textiles and clothing of claim 1 is an alternative
treatment that involves therapeutic uses of color by impacting on human
body's energies, it help to clear negative emotions and energy and restore
balance. All the colors are associated with a different energy centers called
chakra, in the body.
18. The eco friendly textiles and clothing of claim 17 for the alternative
treatment that involves therapeutic uses of color was based on the studying
responses on hundreds of quiz subjects. The results of the psychological quiz
on the subject's exhibits that the characteristics of certain colors have been
identified to cause an emotional response in people.