Description:
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to fabrics, cloth and the like, and more particularly to a novel coating of the medicinal plant extract on the fabric at nano scale consisting essentially of fibers derived from plant material, and still more particularly to the extract obtained from the Fruit/flower / bark / leaf of the different species of Rubiaceae family, which includes Anthocephalns indicus (Kadamb) with fibers derived from other plant materials in a proportionate mix where the coating material content is no less than 10% of the mix and the fiber content derived from other plant materials is no more than 80%.
2. Description of the Related Art
Natural dyes were used to color clothing or other textiles, and by the mid-1800"s chemists began producing synthetic substitutes for them. By the early part of this century only a small percentage of textile dyes were extracted from plants. Lately there has been increasing interest in natural dyes, as the public becomes aware of ecological and environmental problems related to the use of synthetic dyes. Natural dyes are derived from naturally occurring sources such as plant, insects, animals and minerals. Among the all natural dyes, plant-based pigments have wide range of medicinal values. In India, there are more than 450 plants that can yield dyes. In addition to their dye-yielding characteristics, some of these plants also possess medicinal value

The two major areas of concern and problems for people with chemical sensitivities purchasing clothing are the dyes and garment finishing. Garment finishes for wrinkle-free, stain resistant, flame retardant, anti-fungal, anti-bacterial, anti-static, and odor-resistant, permanent-press, non-shrink, softening agents, and the other easy care treatments that are applied to new clothing can be especially harmful for a person with chemical sensitivities. Which is basically all of us - it is just the degree of sensitivity that varies.
Conventional clothing dyes and garment finishes can cause a wide variety of health problems for chemically sensitive people ranging from skin rashes, headache, trouble concentrating, nausea, diarrhea, fatigue, muscle and joint pain, dizziness, difficulty breathing, irregular heart beat, and seizures. Symptoms in children include red cheeks and ears, dark circles under the eyes, hyperactivity, and behavior or learning problems.
It is often the dye fixative which is used to bond the dye color to the fabric that causes the most problems. Unfortunately, heavy metals have often been used in dye fixatives and also in dyes. Toxic chemicals sometimes found in the dyeing process include:
. DLOXIN - A CARCINOGEN AND POSSIBLE HORMONE DISRUPTER;
. TOXIC HEAVY METALS SUCH AS CHROME, COPPER, AND ZINC - KNOWN CARCINOGENS;
. FORMALDEHYDE - A SUSPECTED CARCINOGEN;
. Azo DYES GROUP III A1 AND A2 - WHICH GIVE OFF CARCINOGENIC AMINES;

Because clothing comes into prolonged contact with your skin, toxic chemicals are absorbed through your skin, especially when your body is warm and skin pores have opened to permit perspiration. Once absorbed by humans, heavy metals tend to accumulate in the liver, kidney, bones, heart and brain. The effects on health can be significant when high levels of accumulation are reached. The effect is particularly serious in children due to effects on growth and their relatively low body mass. Use of natural dyes cuts down significantly on the amount of toxic effluent resulting from the synthetic dye process.
Fabrics containing fibers derived from plant materials are well-known. One type of process for producing such yarns is the production of vicose rayon, patterned after the Chardonnet process in which cellulose is first converted to a soluble compound. In this process, developed in 1892 by three British chemists, the cellulose is dissolved to form a viscous liquid known as "vicose".The raw materials for viscose rayon can be cotton linters, the short fibers adhering to the cotton seed, or wood pulp derived from a variety of timber species, including redwood (U.S. Pat. No. 123,810 to Cone), cedar (U.S. Pat. No. 130,171 to Woodley), and southern yellow pine (U.S. Pat. No. 4,874,465 to Cochrane et al. ).

Prior Art: -
A Polish research team developed a technology of silver application into textiles in order to obtain their special biophysiological properties. The use of antimicrobial, antistatic and electro-conductive properties in textiles results in very significant therapeutic benefits in health protection. The technology may be of interest to many textile producers. Research and industrial partners for technical cooperation, further development and testing new generation of textile products are sought.
A research and development organisation established in 1957 has a big expertise in solving problems of The Polish textile industry. The scope of research activities includes processing technologies as well as the application and promotion of textile products made from natural fibres and blends of natural and chemical fibres. 1 he institute specialises in creative designing and development of novel structures, end-use properties and external forms of textiles. Modern methods of textile raw materials and products assessment are used, and quality assurance systems according to the ISO (International Standard Organisation) and PN (Polish national) standards.
The use of silver for medical and therapeutic purposes has been known about for many years, ever since the "magic health properties" of silver were discovered. Modern medicine has found silver to be a very effective, natural and antimicrobial element when used in wound dressings, bandages, underwear and apparel textile materials. The appropriate use of silver properties in textile structures provides also an opportunity for obtaining suitable thermal conditions. Silver also possesses electro-conductive and electrostatic properties. Using the above-mentioned silver properties in textiles is of interest to many fibre, yarn and textile producers.Yarns with silver content are produced in different varieties:Core

yarns have a core made of ultra thin filament silver fibres and braid, and are made of natural and chemical fibres. Yarns with traditional fibres coated in pure silver. The fibres may be staple or filament, or may be blended with traditional fibres.Straw and bamboo are both used to make hats. Straw, a dried form of grass, is also used for stuffing, as is kapok.Fibres from pulpwood trees, cotton, rice, hemp, and nettle are used in making paper.Cotton, flax, jute, hemp, modal and even bamboo fibre are all used in clothing. Piha (pineapple fibre) and ramie are also fibres used in clothing, generally with a blend of other fibres such as cotton.Acetate is used to increase the shininess of certain fabrics such as silks, velvets, and taffetas.Seaweed is used in the production of textiles. A water-soluble fibre known as alginate is produced and is used as a holding fibre; when the cloth is finished, the alginate is dissolved, leaving an open areaLyocellis a man-made fabric derived from wood pulp. It is often described as a man-made silk equivalent and is a tough fabric which is often blended with other fabrics - cotton for example.
Anthocephalus cadamba is much known to its hypolipidemic action in ayurvedic. The hypolipidemic action of Anthocephalus indicus (family, Rubiaceae: Hindi name. Kadam) fruit extract has been studied in hyperlipidemic rats fed a triton- and cholesterol-rich high-fat diet. In triton WR-1339-induced hyperlipidemic rats, feeding with the fruit extract (500 mg/kg b.w.) exerted a lipid-lowering effect as assessed by reversal of plasma levels of total cholesterol, phospholipids, and triglyceride following reactivation of the post-heparin lipolytic activity. In another model, chronic feeding of this natural product (500 mg/kg, b.w.) to animals simultaneously fed a high-fat diet for 30 days caused lowering of lipid levels in plasma and liver accompanied with stimulation of hepatic lipolytic activity. The hypolipidemic activity of Anthocephalus indicus fruit extracts iscompared with guggulipid, a known lipid-lowering drug, in both models.

Kumar .V et al. reported the Lipid Lowering Activity of Anthocephalus indicus Root in Hyperlipidemic Rats.The lipid lowering activity of Anthocephalus indieus (family Rubiaceae; Hindi name Kadamba) root extract has been studied in triton WR-1339 induced hyperlipidemia in rats. In this model, feeding with root extract (500 mg kg-1 b.w.) lowered plasma lipids and reactivated post-heparin lipolytic activity in hyperlipidemic rats. Furthermore, the root extract (50-500 µM) inhibited the generation of superoxide anions and hydroxyl radicals, in both enzymic and non-enzymic systems, in vitro. The results of the present study demonstrated both lipid lowering and antioxidant activities in root extract of A. indicas, which could help prevention of hyperlipidemia and related diseases.
The fruit and inflorescences are reportedly edible. Fodder: The fresh leaves are fed to cattle. The fragrant orange flowers attract pollinators. Timber: Sapwood white with a light yellow tinge becoming creamy yellow on exposure; not clearly differentiated from the heartwood. The wood has a density of 290-560 kg/cu m at 15% moisture content, a fine to medium texture; straight grain; low luster and has no characteristic odor or taste. It is easy to work with hand and machine tools, cuts cleanly, gives a very good surface and is easy to nail. However, the wood is rated as non-durable, graveyard tests in Indonesia show an average life in contact with the ground of less than 1.5 years. The timber air dries rapidly with little or no degrade. Kadamb wood is very easy to preserve using either open tank or pressure-vacuum systems. The timber is used for plywood, light construction, pulp and paper, boxes and crates, dug-out canoes, and furniture components. Kadamb yields a pulp of satisfactory brightness and performance as a handsheet. The wood can be easily impregnated with synthetic resins to increase its density and compressive strength. Kadam is becoming one of the most frequently planted trees in the tropics.

Tannin or dyestuff: A yellow dye can be obtained from the root bark. Essential oil: Kadam flowers are an important raw material in the production of 'attar', which are Indian perfumes with sandalwood (Santalum spp.) base in which one of the essences is absorbed through hydro-distillation. Poison: The flowers exhibit slight anti-implantation activity in test animals. Kadam extracts exhibit nematicidal effects on Meloidogyne incognita. Medicine: The dried bark is used to relieve fever and as a tonic. An extract of the leaves serves as a mouth gargle. Other products: Chlorogenic acid (CGA), isolated from the leaves of A. cadamba screened for hepatoprotective activity in vitro and in vivo inhibited lipid peroxidation in liver microsomes (Kapil A. et al. 1995). The alkaloids cadamine and isocadamine are isolated from the leaves of kadam.
Anthocephalus cadamba is known to its hypolipidemic action but no prior art disclose the use of the wood, bark and root of the Anthocephalus cadamba for making the textile and dying and coating of that textile by bioactive molecules extracted from the parts of the plant and use of clothing for the prevention of type -1 Diabetes. The present invention comprises weaving, knitting, crocheting, knotting of textile from plant fibers of Anthocephalus indicus.
Against this background, the inventor has discovered new, highly efficient anti diabetic clothing exhibiting significantly higher absorbency and strength when compared with other clothing from rayon and similar materials as well as cotton, the new material being comprised of a mixture of fibers derived from Rublaceae family, which includes Anthocephalus indicus (Kadamb) and other natural, non-synthetic materials.

The process for making the fabric of the present invention entails steps which are substantially similar to current conventional processes for producing cotton, with the exception that the wood raw material used in the process of the present invention is a Anthocephalus indicus pulp to prevent the type -1 Diabetes.
OBJECTS OF THE PRESENT INVENTION
It is therefore a principal object of the present invention is to develop the natural organic fiber colored with the natural dye designed for enhancing a wearer's as colored cloth, while giving the wearer's a very natural appearance with therapeutic property with many other benefits used in colour therapy .
Another object of the invention is to provide the all natural cloth or fabric which exhibits superior strength and moisture absorbency characteristics and the prevention of Diabetes. The invention comprises a natural colored organic natural fiber which includes a prevention of Diabetes.
Still another object of the invention is to provide a novel cloth or fabric which durability of the treated sample was found good even after 50 wash. The principle for therapeutic value of textile is the rubbing fastness of medicinal plant active ingredients and trans dermal application. The beneficial aspects of the medicinal plant dyes in comparison to any of the synthetic dyes are high.
The objects and features of the present invention, which are believed to be novel, are set forth with particularity in the appended claims. The present invention, together with further objects and advantages, may best be understood by reference to the following detailed description.

DETAILED DESCRIPTION OF THE INVENTION
Our body can loses toxins and its metabolism can be enhanced by wearing the therapeutic clothing. Conventional Western medicine and traditional Eastern medicine recognize the skin as being the body's largest organ. The skin can act as a barrier but also as a conduit for outside substances to enter the body. Many environmental toxins and chemicals in conventional clothing are assimilated into the body through the skin. Anything which can improve the skin's natural ability to block and resist harmful chemicals and toxins from entering the body will be beneficial to health.
Ayurveda identifies seven unique layers of the skin where each layer has a distinct function. Starting from the outermost layer, the seven layers defined by Ayurveda arc A\abhasini. I.ohita. Shweta. Tamra. Vedini. Rohini and Mamsadhara.
The fourth layer. Tamra. supports the immune s\slem and performs the function of acting as a barrier. Skin infections reflect an imbalance in this layer. The fabric of the present invention was improving the skin's ability to act as a barrier to external and environmental toxins: the wearer's health was improved.
Now that a connection has been established between exposure to intense sunlight and the skin, many people are protecting themselves against overexposure to the sun by using what are called sunscreen agents, which contain UV filters or absorbers. The UV absorbers or UV filters are organic substances which are able to absorb electromagnetic radiation in the UV range.

The skin is an efficient barrier to the penetration of water soluble substances, and the rate of transdermal pharmaceutical agent absorption is primarily determined by the agent's lipid solubility, water solubility, and polarity. Highly polar or water soluble pharmaceutical agents are effectively blocked by the skin. Even very lipophilic pharmaceutical agents penetrate the dermis very slowly compared with the rate of penetration across cell membranes
Penetration Enhancers", in Transdermal Delivery of Drugs, Vol. II, Kyodonieus et al.. Eds., CRC Press, Boca Raton, Fla. Few pharmaceutical agents fit this profile and those which do are not always predictably absorbed. Various forms of chemical enhancers, such as those enhancing lipophilicity, have been developed to improve transdermal transport when physically mixed with certain therapeutic agents and provide more predictable absorption.
Anthocephalus cadamba -BOTANIC DESCRIPTION
Anthocephalus cadamba is a large tree with a broad crown and straight cylindrical bole. The tree: may reach a height of 45 m with trunk diameters of 100-(160) cm. The tree sometimes has small buttresses and a broad crown. The bark is gray, smooth in young trees, rough and longitudinally fissured in old trees. Leaves glossy green, opposite, simple more or less sessile to petiolate, ovate to elliptical (15-50 x 8-25 cm). Inflorescence in clusters; terminal globose heads without bracteoles, subsessile fragrant, orange or yellow flowers; Flowers bisexual, 5-merous, calyx tube funnel-shaped, corolla gamopetalous saucer-shaped with a narrow tube, the narrow lobes imbricate in bud. Stamens 5, inserted on the corolla tube, filaments short, anthers basifixed. Ovary inferior, bi-locular, sometimes 4-locular in the upper part, style exserted and a spindle-shaped stigma. Fruitlets numerous with their upper parts containing 4 hollow or solid structures. Seed

trigonal or irregularly shaped. A. cadamba is closely allied to the subtribe Naucleinae (Rubiaceae) but differs from them in its placentation mode. The species is in the focus of a classification controversy based on the name of the original type specimen described by Lamarck.
Optimum extraction condition for the extraction of bioactive dye from Anthocephalus cadamba
Selection of solvent
Selection of solvent including methanol,acetone,2-propanol,dichloroethane,diethyl ether, ethyl acetate ,chloroform ,hexane and water was carried out according to different functional groups.0.5g of tea were soaked in 100 ml of respective solvent at 25°C for 24 hours.
Maximum Amount of Dye Extracted
Optimum dye extraction was determined by extraction various amount of bioactive dye from Anthocephalus cadamba ,i.e.5,10,20,30g,respectively,in 100ml of water at 100° C for 90 min.
Optimum Temperature
Optimum temperature for dye extraction was determined by extracting 20g of dye in 100ml of solvent at different temperatures,i.e.25,50,75 and 100° C respectively .for 90 min.

Optimum Time
Optimum time for dye extraction was determined at 100° C by extraction 20g of dye in 100ml of solvent for different time intervals,i.e.5,10,20,30,60,90,120 and 180 min. respectively .The amount of dye extracted under different conditions was measured by spectrophotometer at 420nm.
Treatment of fiber :- The root extract of Anthocephalus indicus (600 g) was dissolved in water (1000 ml), and cotton (5 g) was added. The bath was heated from 30° C.-90° C. over 1 hour and sodium sulphate (0.750 g) was added. After a further 30 minutes, tris (2-aminoethyl)amine(0.0024 g) was added and the dye bath heated at 90° C. for 1 hour. The exhausted dye bath was completely colourless and the cloth was dyed in a shiny yellow shade with excellent wash-fastness.
According to the objective of the invention the process for making the fabric of the present invention entails steps which are substantially similar to current conventional processes for producing cotton, with the exception that the wood raw material used in the process of the present invention is a Anthocephalus iiuiicus pulp.
In the present invention textiles was formed by weaving, knitting, crocheting, knotting of Anthocephalus indicus plant fibers pressing together.
Before the spinning step, the wood pulp was mixed with cotton fibers. A preferred mixture is one in which the different fibers exist in a proportionate ratio of 20%-25% Inthocephalus indicus fibers and 80% cotton fibers.
The fibers produced by the present invention have high strength, especially when wet. and good dimensional stabillity and firmness. In addition, the fibers produced by the process of the invention are highly absorbent

The fibers which result from the process of the present invention will be used in the manufacture of clothing, as medical fabrics.
Coating is a common technique used to apply dye particles onto textiles. The coating compositions that can modify the surface of textiles are usually composed of micro-particles, a surfactant, ingredients and a carrier medium. Several methods can apply coating onto fabrics, including spraying, transfer printing, washing, rinsing and padding. Of these methods, padding is the most commonly used. The nano-particles are attached to the fabrics with the use of a padder adjusted to suitable pressure and speed, followed by drying and curing.
Coating enhance and extend the range of functional performance properties of textiles and the use of this techniques is growing rapidly as the applications for technical textiles become more diverse. Coating is a process in which a polymeric layer is applied directly to one or both surfaces of the fabric
• Coating can mostly be used of products which having capacity to convert in viscose liquid form. This viscose liquid so easily can spread over the surface and form coating.
• Drying or curing process which hardens the coating to produce a non blocking product.
• Due to viscosity requirement it is limited to linear polymers, which can be coated as a polymer melt or solution and on cooling, form a solid film or form solid film on evaporation of the solvent.
• There are some types of coatings that can be applied in the liquid form and then chemically cross-linked to form a solid-film.

In the present invention a bioactive functional material from plant Anthocephalus indiens, was coated as monofilament that forms coated fabric without losing the fabric's texture.
Examples
Example -1 Bioactive functional material from plant Anthocephalus indicus was coated as per heavy-duty technical textile coating 700 gm bioactive functional material was applied onto the fabric
Example -2 Three layers of bioactive functional material was applied
Example -3 In the present invention we developed a nano-scale processing technology that allows molecular arrangement and molecular self-assembly necessary to bring out further advanced functionalities in textile processing than the existing dyeing processing.
Example -4 Natural dyes obtained from the root bark and flowers of the Anthoceplulus indicus has yellow to red-hue colorant that is substantially free of alkaloids and polyphenoloxidase, has good stability, minimal aroma, and does not contain any organic solvent residuals is provided.

Example -5 The natural colorant has a red-hue equivalent to the red-hue of FD&C Red No. 40 and is more stable as compared to existing natural colorants. Methods for extracting dye from Anthocephalus indicus has minimum use of an organic solvent, while essentially eliminating alkaloids and polyphenoloxidase from the extract are also provided. Anthocephalus indicus root was pressed and filtered and the filtrate is concentrated.
Example -6 The pH of the concentrate is adjusted with alkali to precipitate alkaloids therein. The concentrate is filtered and the pH of the filtrate is adjusted to a pH value of about 3.5 or lower. The pH is adjusted in such a manner to obtain a colorant having the desired yellow to red-hue color.
Example -7. The finished fabric samples have been tested for the specific activity related with the disease by in-vitro trials. The natural dye treated fabrics was exhibited significant prevention of diabetes.
Example -8. The wash durability of the treated sample was found good even after 50 wash. The principle for therapeutic value of textile is the rubbing fastness of medicinal plant active ingredients and trans dermal application. The beneficial aspects of the medicinal plant dyes in comparison to any of the synthetic dyes are high. Chemically created colors are terrible poisons.
Example -9. The finished fabric samples was exhibits an eco friendly properties which is organic and 100 % natural, which colored and coated by accurate and specified medicinal plants describes in Ayurvedic text for the prevention of Diabetes. Some selective species of medicinal plants were identified and screened for their activity and the extracts were applied to cotton fabrics.
Example -10. The finished fabric samples were exhibits the preventive property for Diabetes described in Ayurvedic text.

Example -11. Clinical study was conducted to test the efficacy of medicated cloths was done at Clinical research centre of Patanjali. Clinical Research Centre of Patanjali undertook a six-month clinical trial at on patients suffering from type -1 Diabetes, For the study, all clothes, bed linens and mattresses of the patients were uniformly coated and dyed in nano-scale sizes by the bioactive material from the plant in Anthocephalus indicus . The significant improvements in the health of patients suffering from type -1 Diabetes were exhibit. We can bring to a close that the present treatments might have healthy benefits that extend beyond the periphery of skin problems.
Those skilled in the art will appreciate that various adoptions and modifications of the just-described preferred embodiments can be configured without departing from the scope and spirit of the invention. Therefore, it is to be understood that, within the scope of the appended claims, the invention may be practiced other than as specifically described herein.
The following description is provided to enable any person skilled in the art to make and use the invention and, with reference to the drawings, sets forth the best mode contemplated by the inventor of carrying out this invention.
Various modifications, however, will remain readily apparent to those skilled in the art, since the generic principles of the present invention have been defined herein specifically to provide an improved fabric made entirely of plant materials, and which exhibits high absorbency, abrasion resistance, and tensile strength.

What it claimed is:
1. Therapeutic clothing comprising an Organic fabric in which Implementing of medicinal plant Anthocephalus indicus fibres into textile fabrics for medical and therapeutic purposes
2. The therapeutic clothing claim 1 was dyed and coated by the highly bioactive plant extract of Anthocephalus indicus at nano size scale by padder adjusted to suitable pressure and speed, followed by drying and curing with natural colour which have a therapeutic property for the prevention of Diabetes.
3. A process according to claim 1 or 2 for the coloration of a substrate comprising the steps:

(a) applying an aqueous solution of the dye to the substrate;
(b) bringing the nucleophilic agent into contact with the substrate.

4. The therapeutic clothing claim 2 where the fabric is selected from the clothing that is made from materials that was grown without the use of synthetic chemicals such as pesticides - herbicides or other chemicals.
5. The therapeutic clothing of claim 2 where the fabric is composed of pulp of cotton, silk and wool.
6. The therapeutic clothing claim 1 where the first therapeutic agent for the prevention Diabetes is the bioactive extract and natural colour obtained from
the Fruit/flower / bark / leaf and root of the different species of Rubiaceae family, which includes Anthocephalus indicus (Kadamb).
7. The product of claim 1 where the entire ingredient claimed as therapeutic
agent for the dyeing of organic fiber and cloths was tested for their efficacy
by various in-vivo and in-vitro clinical trail the results was very significant
for the prevention of Diabetes.
8. The therapeutic clothing claim 1 has permanent medicinal properties up to
fifty wash in comparison with the other therapeutic clothing which provides
temporary effects.
9. The therapeutic clothing claim 7 ,comprise the novel textile designs that
assure belter physical, hygienic and utility properties (comfort) in relation to
conventional fabrics made of traditional yarns.