Abstract: Asthma is a chronic inflammation of the lungs in which the airways (bronchi) are reversibly narrowed. Asthma affects 7% of the population, and 300 million worldwide. During attacks (exacerbations), the smooth muscle cells in the bronchi constrict, and the airways become inflamed and swollen. Breathing becomes difficult, and asthma causes 4,000 deaths a year in the U.S. Dyeing of vastra with the specific medicinal herbs for specific dosha (Vata, Pitta and Kapha) is prescribed in Ayurveda. When vastra exposed to skin, the herbs are absorbed into the body and function as a means of providing ayurvedic treatment for a broad range of diseases including asthma. It is also known to strengthen the immune system. Experimental research confirms that medicinal plant pigment dyeing of organic natural fiber helps in treating and preventing the asthma. Novel textiles for treating and preventing the asthma, made from organic cotton, coloring and coating with different natural colour derived from various medicinal plants describes in ayurvedic text is the natural fiber which colored with natural dye. Currently existing garments products, such as shirt, trousers, skirt, sari etc. are made from non coated libers and do not include any bioactive coating agent applied topically to the liber which have anti asthmatic effect by controlled release processes by the cloth media surface during normal use through the skin. However, till the date none of garments individually demonstrate a therapeutic effect by skin absorption on prevention and treatment of asthma.
Description:
FIELD OF THE INVENTION
Novel textiles for treating and preventing the Asthma is composed of bio active cellulosic textile compositions, which can be easily placed in contact with infected human skin in regular clothing, or worn for the treatment and cure of respiratory diseases. The Anti asthmatic bio active compound extracted from the two plants, is bonded to cellulose or cellulose-containing materials, or finished articles of clothing.
BACKGROUND
Respiratory disorder
Naturally occurring fibers, such as cellulose fibers, e.g., cotton and flax; wool; and the like possess properties such as moisture absorption, which renders them superior in many respects to synthetic fibers.
To overcome this problem, the prior art has described treating of naturally occurring fibers, such as cotton fibers, with various anti asthma agents to inhibit the growth of bacteria and fungus. Because of the fact that the fibers are naturally occurring, such treatment can only be a surface treatment whereby the highly bioactive agent is applied to the fibers by padding or dipping of the fabric, or the like. While a treatment of this nature temporarily inhibits bacterial and fungal growth, the anti asthma agent is removed from the surface of the fibers after a limited period of time as a result of wearing of the garments and particularly during laundering. To date, no means has been proposed whereby fungicidally active cellulosic textile compositions properties could be more permanently imparted to naturally occurring fibers so that the fibers would possess anti asthmatic properties over the life of the garment into which they are incorporated.
OBJECTIVES
It is therefore a principal object of the present invention is to develop the natural organic fiber colored with the natural dye designed for enhancing a wearer's as colored cloth, while giving the wearer's a very natural appearance with therapeutic property with many other benefits used in colour therapy .
Another object of the invention is to provide the all natural cloth or fabric which exhibits superior strength, moisture absorbency characteristics and the treating and preventing the Asthma.
It is. accordingly, the primary objective of the present invention to obviate this problem by providing a novel fabric composition which can be contacted with, and applied to asthma.
A further object is the delivery of the highly bioactive plant extract through medicated clothing which, after use and after washing, can again be worn without application of additional drug to resume treatment of the infected areas of the respiratory disorder.
A specific object is to provide novel medicated garments etc which can be worn by the infected person to effectively treat the infected skin area. It is moistened by perspiration, or moisture from external sources; and the cloths, after use and after washing, can be worn without the application of additional drug to effectively resume the treatment.
Still another object of the invention is to provide a novel cloth or fabric which durability of the treated sample was found good even after 50 wash. The principle for therapeutic value of textile is the rubbing fastness of medicinal plant active ingredients and trans dermal application. The beneficial aspects of the medicinal plant dyes in comparison to any of the synthetic dyes are high.
The objects and features of the present invention, which are believed to be novel, are set forth with particularity in the appended claims. The present invention, together
with further objects and advantages, may best be understood by reference to the following detailed description.
THE INVENTION
These objects and others are achieved in accordance with this invention which embodies a composition, or article of manufacture, comprised of a cellulosic textile material, suitably fibers, yarn, or fabric, or article of manufacture formed from said fibers, yarn, or fabric, to which is chemically bonded a bioactive compound extracted from the Kakada singhi and Camphor.
Kakada Singhi
Common Name: Kakada singhi
Latin Name: Pistacia integerrima
Indian Name: kakar singhi, kakkar, kakra, kakring, kakroi
Description:
Pistacia integerrima is a multi-branched, single stemmed, deciduous tree, up to 25 m tall. The tree has low/dense crown base and roots deeply. Leaves large, up to 25 cm long, pinnate (frequently paripinnate) leaves bearing 2-6 pairs of lanceolate, long leaflets. The terminal leaflet is much smaller than the lateral ones or even reduced to a mucro. Inflorescence red. The fruits are globular, apiculate, 5-6 mm in diameter, purplish or blue at maturity and with a bony endocarp. The name of Pistacia derives from the Persian name 'pisteh' or 'pesteh'. Classification within the genus Pistacia has been based on leaf morphology and geographical distribution.
Remedies For:
The essential oil obtained by steam-distillation of Kakra Singi, the indigenous drug prepared from Pistacia integerrima contains: alpha -pinene (25 %.), camphene (27 %.). di-limonene (4-5%), l:8-cineol (10 %.), alpha -terpineol (20 %.), and
aromadendrene (4-5 per cent.); also a small percentage of a lactonic stearoptene. 15% by volume of the oil is caprylic acid. Medicine: Pistacia integerrima galls are used in traditional medicine to treat coughs, asthma. The plant extracts are used in treating livestock diseases. Other products: Pistacigerrimones C and D from Pistacia integerrima have significant analgesic and anti-inflammatory activity.
Camphor
Common Names: Camphor
Botanical Name: Cinnamomum camphora
Family: Lauraceae
Cinnamomum camphora (commonly known as Camphor tree, Camphorwood or camphor laurel) is a large evergreen tree that grows up to 20-30 metres tall. The leaves have a glossy, waxy appearance and smell of camphor when crushed. It produces clusters of black berry-like fruit around one centimetre in diameter. It has a pale bark that is very rough and fissured vertically.
Camphor is a white crystalline substance, obtained from the tree Cinnamomum camphora. Camphor has been used for many centuries as a culinary spice, a component of incense, and as a medicine. Camphor is also an insect repellent and a flea-killing substance.
Chemical constituents
Camphor laurel contains volatile chemical compounds in all plant parts, and the wood and leaves are steam distilled for the essential oils. Camphor laurel has six different chemical variants called chemotypes, which are camphor, linalool, 1,8-cineole, nerolidol, safrole. or borneol.
Uses
The Karpura oil is massaged in cough, bronchitis, pneumonia, chest-pain and backache, with great benefit. Internally, karpura is used in various diseases. It is extremely beneficial in innumerable maladies like sore throat, foul smell to the oral cavity, asthma, and cough.
Yarn Preparation
The composition of fabric is formed, in a first cellulose activation step, by chemical reaction between a hydroxyl group of the cellulose and a first functional group of bifunctional ligand to link the latter to the cellulose via a covalent bond and a second step, wherein a bioactive extract of medicinal plants which contains a functional group capable of reaction with the second functional group of said bifunctional ligand. is chemically reacted with, attached and bonded to the bioactive extract of medicinal plants by reaction between the functional group constituting a component of said bioactive phenolic compound and the second functional group of said cellulose-ligand. Thus in a cellulose activation step, a bifunctional ligand is attached to the cellulose via reaction between one of the functional groups of the bifunctional ligand and the hydroxyl substituents of the cellulose, the cellulose forming a matrix to which is attached the ligand which yet contains an unreacted functional group. A bioactive extract of medicinal plants, which contains or to which is added a functional group reactive with the unreacted functional group of the ligomer of the cellulose-ligomer complex, is then reacted in a second step with the cellulose-ligomer complex to link the fungicidally extract of medicinal plants to the cellulose. Cellulose fibers, or yarns treated in this manner can then be processed finished articles of clothing made from cellulose fibers, or yarns can be chemically treated in such manner and the bioactive extract of medicinal plants bonded thereto such that the medicinally treated articles of clothing can be worn and employed for effective treatment of the respiratory disorder through skin contact with the clothing.
The cellulosic textile material, after the reaction, retains substantially all of the textile properties characteristic of the untreated cellulose textile material, and retains the uses of the original cellulosic textile material. The hand, feel and appearance remain essentially the same. A yarn, e.g., retains the physical properties of a yarn and can be woven into a fabric. A fabric so-treated retains the physical properties of the original fabric, and can be cut and the parts sewed together to form an article of clothing, and clothing so-treated will remain useful for their original purpose. All after treatment, however, will additionally be suitable as a drug for the treatment of those skin diseases for which the drug bonded to the cellulosic textile material was originally suitable. Preferred articles of medicated clothing are thus those worn in contact with areas of the skin likely to be infected.
The first step in the preparation of the composition of fabric in this invention is to activate the cellulose by attaching a suitable ligand to the cellulose material, suitably a cellulosic fiber, yarn, fabric or article of manufacture produced from such textile materials, this providing the structural unit to which a derivative of the drug, or medicinal can be attached.
The compositions, or articles of manufacture, of this invention can be provided and applied in essentially any shape or form, and can be formed from a cellulose textile material of virtually any shape or form. Suitably, the composition or article of manufacture of this invention is formed from a cellulose textile material, e.g., a fiber, or material shaped as a yarn, or fabric. A cellulosic textile yarn can thus be treated in accordance with the technique described, the yarn then formed into a fabric, and a bandage or an article of clothing, e.g., a sock, then made from the fabric. On the other hand, a cellulose textile fabric can be so treated, and an article of clothing made from the treated fabric; or, the fabric can be made into an article of clothing, e.g., a sock, and the article of clothing treated in accordance with the process of this invention.
EXAMPLE
Optimum extraction condition for the extraction of bioactive material from Kakada
singhi and Camphor
Selection of solvent
Selection of solvent including methanol, acetone,2-propanol,dichloroethane,diethyl
ether, ethyl acetate, chloroform, hexane and water was carried out according to
different functional groups. lOg of each whole herb were soaked in 100 ml of
respective solvent at 25°C for 24 hours.
Maximum Amount of Dye Extracted
Optimum dye extraction was determined by extraction various amount of bioactive
material from Kakada singhi and Camphor, i.e.5, 10, 20, 30 g, respectively, in 100ml
of water at 100° C for 90 min.
Optimum Temperature
Optimum temperature for dye extraction was determined by extracting 20g of
bioactive material in 100ml of solvent at different temperatures, i.e.25, 50, 75 and
100° C. respectively, for 90 min.
Optimum Time
Optimum time for dye extraction was determined at 100° C by extraction 20g of dye
in 100ml of solvent for different time intervals,i.e.5, 10, 20, 30,60,90,120 and 180
min. .respectively .The amount of dye extracted under different conditions was
measured by spectrophotometer at 420nm.
Treatment of fiber: - The root bark leaf, fruit and flower extract of Kakada singhi and
Camphor (each 100 g) was dissolved in water (1000 ml), and cotton (5 g) was added.
The bath was heated from 30° C.-90° C. over 1 hour and sodium sulphate (0.750 g)
was added. After a further 30 minutes, plant pulp was added and the dye bath heated
at 90° C. for 1 hour.
According to the objective of the invention the process for making the fabric of the present invention entails steps which are substantially similar to current conventional processes for producing cotton, with the exception that the cellulose material used in the process of making the fiber in the present invention is a Kakada singhi and Camphor.
In the present invention textiles was formed by weaving, knitting, crocheting, knotting of Kakada singhi and Camphor plant cellulose pressing together. Before the spinning step, the wood pulp was mixed with cotton fibers. A preferred mixture is one in which the different fibers exist in a proportionate ratio of 2%-5% of each. Kakada singhi and Camphor fibers and 80% cotton fibers.
The fibers produced by the present invention have high strength, especially when wet. and good dimensional stability and firmness. In addition, the fibers produced by the process of the invention are highly absorbent
The fibers which result from the process of the present invention will be used in the manufacture of clothing, as medical fabrics.
Coating is a common technique used to apply dye particles onto textiles. The coating compositions that can modify the surface of textiles are usually composed of micro-particles, a surfactant, ingredients and a carrier medium. Several methods can apply coating onto fabrics, including spraying, transfer printing, washing, rinsing and padding. Of these methods, padding is the most commonly used. The nano-particles are attached to the fabrics with the use of a padder adjusted to suitable pressure and speed, followed by drying and curing.
Coating enhance and extend the range of functional performance properties of textiles and the use of this techniques is growing rapidly as the applications for technical textiles become more diverse. Coating is a process in which a polymeric layer is applied directly to one or both surfaces of the fabric
• Coating can mostly be used of products which having capacity to convert in viscose liquid form. This viscose liquid so easily can spread over the surface and form coating.
• Drying or curing process which hardens the coating to produce a non blocking product.
• Due to viscosity requirement it is limited to linear polymers, which can be coated as a polymer melt or solution and on cooling, form a solid film or form solid film on evaporation of the solvent.
• There are some types of coatings that can be applied in the liquid form and then chemically cross-linked to form a solid-film.
In the present invention a bioactive functional material from plants Kakada singhi and Camphor were coated as monofilament that forms coated fabric without losing the fabric's texture. The exhausted dye bath was completely colourless and the cloth was dyed in a shiny green shade with excellent wash-fastness.
Examples
Example -1. Bioactive functional material from plants Kakada singhi and Camphor were coated as per heavy-duty technical textile coating 700 gm bioactive functional material was applied onto the fabric
Example -2. Three layers of bioactive functional material was applied
Example -3. In the present invention we developed a nano-scale processing technology that allows molecular arrangement and molecular self-assembly necessary
to bring out further advanced functionalities in textile processing than the existing dyeing processing.
Example -4 Natural dyes obtained from the root bark, leaves and flowers of the Kakada singhi and Camphor have yellow to orange colorant that is substantially free of alkaloids and polyphenoloxidase, has good stability, minimal aroma, and does not contain any organic solvent residuals is provided.
Example -5 The natural colorant has a have yellow to orange equivalent to the other synthetic colorant and is more stable as compared to existing natural colorants. Methods for extracting dyes from Kakada singhi and Camphor has minimum use of an organic solvent, while essentially eliminating skin irritating polyphenoloxidase from the extract are also provided. Kakada singhi and Camphor was pressed and filtered and the filtrate is concentrated.
Example -6 The pH of the concentrate is adjusted with alkali to precipitate alkaloids therein. The concentrate is filtered and the pH of the filtrate is adjusted to a pH value of about 3.5 or lower. The pH is adjusted in such a manner to obtain a colorant having the desired yellow to orange color.
Example -7. The finished fabric samples have been tested for the specific activity related with the disease by in-vitro trials. The natural dye treated fabrics was exhibited significant prevention and treatment of respiratory disorder.
Example -8. The wash durability of the treated sample was found good even after 50 wash. The principle for therapeutic value of textile is the rubbing fastness of medicinal plant active ingredients, trans dermal application and release of therapeutic volatile compounds . The beneficial aspects of the medicinal plant dyes in comparison to any of the synthetic dyes are high. Chemically created colors are terrible poisons.
Example -9. The finished fabric samples was exhibits an eco friendly properties which is organic and 100 % natural, which colored and coated by accurate and specified medicinal plants describes in Ayurvedic text for the prevention and treatment of Respiratory diseases. Some selective species of medicinal plants were identified and screened for their activity and the extracts were applied to cotton fabrics.
Example -10. The finished fabric samples were exhibits the prevention and treatment of Respiratory diseases described in Ayurvedic text.
Example -11. Clinical study was conducted to test the efficacy of medicated cloths was done at Clinical research centre of Patanjali. Clinical Research Centre of Patanjali undertook a six-month clinical trial at on patients suffering from type -1 Diabetes. For the study, all clothes, bed linens and mattresses of the patients were uniformly coated and dyed in nano-scale sizes by the bioactive material from the plants Kakada singhi and Camphor. The significant improvements in the health of patients suffering from Respiratory diseases were exhibit.
Those skilled in the art will appreciate that various adoptions and modifications of the just-described preferred embodiments can be configured without departing from the scope and spirit of the invention. Therefore, it is to be understood that, within the scope of the appended claims, the invention may be practiced other than as specifically described herein.
The following description is provided to enable any person skilled in the art to make and use the invention and, with reference to the drawings, sets forth the best mode contemplated by the inventor of carrying out this invention.
Various modifications, however, will remain readily apparent to those skilled in the art. since the generic principles of the present invention have been defined herein
specifically to provide an improved fabric made entirely of plant materials, and which exhibits high absorbency, abrasion resistance, and tensile strength.
What it claimed is:
1. Therapeutic clothing comprising an Organic fabric whose dye with natural colour which have a therapeutic property for the prevention and treatment of Asthama.
2. The therapeutic clothing claim 1 where the fabric is selected from the clothing that is made from materials that was grown without the use of synthetic chemicals such as pesticides - herbicides or other chemicals.
3. The therapeutic clothing of claim 2 where the fabric is cotton, silk and wool.
4. The therapeutic clothing claim 1 where the first therapeutic agent for the prevention and treatment of Asthama is the natural colour and active principles obtained from the Leaves and bark from the different species of family Lauraceae, which includes Camphor {Cinnamomum camphora).
5. The therapeutic clothing claim 1 where the first therapeutic agent for the prevention and treatment of Asthama is the natural colour obtained from the Fruits and Leaves of the different species of Anacardiaceae family, which includes Kakada singhi (Pistacia integerrima).
6. The product of claim 1 where the entire ingredient claimed as therapeutic agent for the dyeing of organic fiber and cloths was tested for their efficacy by various in-vivo and in-vitro clinical trail the results was very significant on prevention and treatment of Asthama.
7. The in-vivo and in-vitro clinical trail claim 7 where common respiratory function test were used for measuring the effect of dye and other active ingredient claimed as anti asthmatic.
8. A method of making an therapeutic product comprising contacting a fabric dye and treated with an natural colors and other active ingredients from the various parts of the plant Kakada singhi (Pistacia integerrima) and Camphor (Cinnamomum camphora).
| # | Name | Date |
|---|---|---|
| 1 | 1605-del-2009-abstract.pdf | 2011-08-21 |
| 1 | 1605-DEL-2009-Form-2-(04-08-2010).pdf | 2010-08-04 |
| 2 | 1605-del-2009-claims.pdf | 2011-08-21 |
| 2 | 1605-DEL-2009-Form-1-(04-08-2010).pdf | 2010-08-04 |
| 3 | 1605-DEL-2009-Description (Complete)-(04-08-2010).pdf | 2010-08-04 |
| 3 | 1605-del-2009-form-1.pdf | 2011-08-21 |
| 4 | 1605-DEL-2009-Correspondence-Others-(04-08-2010).pdf | 2010-08-04 |
| 4 | 1605-del-2009-form-2.pdf | 2011-08-21 |
| 5 | 1605-DEL-2009-Claims-(04-08-2010).pdf | 2010-08-04 |
| 5 | 1605-DEL-2009-Abstract-(04-08-2010).pdf | 2010-08-04 |
| 6 | 1605-DEL-2009-Abstract-(04-08-2010).pdf | 2010-08-04 |
| 6 | 1605-DEL-2009-Claims-(04-08-2010).pdf | 2010-08-04 |
| 7 | 1605-DEL-2009-Correspondence-Others-(04-08-2010).pdf | 2010-08-04 |
| 7 | 1605-del-2009-form-2.pdf | 2011-08-21 |
| 8 | 1605-DEL-2009-Description (Complete)-(04-08-2010).pdf | 2010-08-04 |
| 8 | 1605-del-2009-form-1.pdf | 2011-08-21 |
| 9 | 1605-del-2009-claims.pdf | 2011-08-21 |
| 9 | 1605-DEL-2009-Form-1-(04-08-2010).pdf | 2010-08-04 |
| 10 | 1605-DEL-2009-Form-2-(04-08-2010).pdf | 2010-08-04 |
| 10 | 1605-del-2009-abstract.pdf | 2011-08-21 |