Description:
FIELD OF THE INVENTION
Novel textiles for treating and preventing the Skin disease is composed of fungicidally active cellulosic textile compositions, which can be easily placed in contact with infected human skin in regular clothing , or worn for the treatment and cure of skin diseases. The fungicidally bio active compound extracted from the three plants , is bonded to cellulose or cellulose-containing materials, or finished articles of clothing, notably e.g., socks, rendering these materials useful for the treatment and cure of skin diseases caused by fungi infections over the infected skin areas with which they are in contact. These materials, is used as finished articles of clothing, can be washed, dried, and reused over-and-over without addition of a fresh drug, for effective continuing treatment of a skin disease.Skin disease is a very broad term that describes numerous conditions. Some skin diseases are serious and deadly, while others are just annoying. Some skin diseases are disfiguring, while others are barely visible.
BACKGROUND
The human skin is subject to many diseases, some inconsequential and passing, some chronic and productive of partial or total disability, and others associated with congenital or acquired systemic diseases. One common type of skin disease is caused by fungi, e.g., ringworm of the scalp, athlete's foot, and jockstrap itch. Fungi, a class of primitive plants, include microscopic organisms capable of producing infections of the skin, or the skin and internal organs as well. Ringworm (Tinea) is the inclusive name given for a number of superficial infections caused by the fungi Trichophyton, Microsporum, and Epidermophyton. These organisms feed on keraton. the protein building material of the nails, hair, and stratum corneum. These types of skin infections are known to respond to certain types of drugs, e.g., Griseofulvin. a fungicidal antibiotic, or to such fungicidal phenolic compounds as p-aminophenol or p-aminosalicyclic acid, or both. A difficulty in treating these types of infections however is that it is often difficult, and sometimes virtually impossible to maintain contact between the drug, and the infected areas of the skin for a sufficiently adequate period to destroy the organisms: and, if the organisms are not essentially completely destroyed growth of the organisms reoccur.
Naturally occurring fibers, such as cellulose fibers, e.g., cotton and flax; wool; and the like possess properties such as moisture absorption, which renders them superior in many respects to synthetic fibers. For this reason, these fibers, and particularly cotton fibers, are commonly used in preparing garments which come into contact with the human skin, such as underwear and socks. A problem is presented in the wearing of such garments, however, since the warmth and moisture of the human skin causes rapid growth of bacteria and fungus on the
fibers forming these garments leading to the generation of body odors and possible infections.
To overcome this problem, the prior art has described treating of naturally occurring fibers, such as cotton fibers, with various antimicrobial agents to inhibit the growth of bacteria and fungus. Because of the fact that the fibers are naturally occurring, such treatment can only be a surface treatment whereby the highly bioactive agent is applied to the fibers by padding or dipping of the fabric, or the like. While a treatment of this nature temporarily inhibits bacterial and fungal growth, the antimicrobial agent is removed from the surface of the fibers after a limited period of time as a result of wearing of the garments and particularly during laundering. To date, no means has been proposed whereby fungicidally active cellulosic textile compositions properties could be more permanently imparted to naturally occurring fibers so that the fibers would possess fungicidally properties over the life of the garment into which they are incorporated.
OBJECTS
It is therefore a principal object of the present invention is to develop the natural organic fiber colored with the natural dye designed for enhancing a wearer's as colored cloth, while giving the wearer's a very natural appearance with therapeutic property with many other benefits used in colour therapy ,
Another object of the invention is to provide the all natural cloth or fabric which exhibits superior strength, moisture absorbency characteristics and the treating and preventing the Skin disease .
It is. accordingly, the primary objective of the present invention to obviate this problem by providing a novel fabric composition which can be contacted with, and applied to an infected skin area such that the concentration of the drug will not be diminished when the infected area is moistened through perspiration, or external climatic or environmental conditions or sources.
A further object is the delivery of the highly bioactive plant extract through medicated clothing which, after use and after washing, can again be worn without application of additional drug to resume treatment of the infected areas of the skin.
A specific object is to provide novel medicated shirt, under wear ,bra etc which can be worn by the infected person to effectively treat the infected skin area albeit it is moistened by perspiration, or moisture from external sources; and the cloths , after use and after washing, can be worn without the application of additional drug to effectively resume the treatment.
Still another object of the invention is to provide a novel cloth or fabric which durability of the treated sample was found good even after 50 wash. The principle for therapeutic value of textile is the rubbing fastness of medicinal plant active
ingredients and trans dermal application. The beneficial aspects of the medicinal plant dyes in comparison to any of the synthetic dyes are high.
The objects and features of the present invention, which are believed to be novel, are set forth with particularity in the appended claims. The present invention, together with further objects and advantages, may best be understood by reference to the following detailed description.
THE INVENTION
These objects and others are achieved in accordance with this invention which embodies a composition, or article of manufacture, comprised of a cellulosic textile material, suitably fibers, yarn, or fabric, or article of manufacture formed from said fibers, yarn, or fabric, to which is chemically bonded a fungicidally active compound Extracted from the Mamishtha, Alovera , Palas (Tesu) Daru haldi
Latin Name : Rubia cordifolia
Common Names : Indian Madder
Indian Name : Manjishtha, Manjit
Parts Used : Root
Description: This Ayurvedic herb is a climbing plant found in the Himalayas and hill stations in India.
Remedies For: Alterative, anti-tumor, astringent, diuretic, emmenagogue, hemostatic, lithotriptic
The traditional therapeutic use of the plant has been in skin disorders as it is a blood purifing herb. It is used as an immune regulator, (its role in supporting heart health is evidenced by studies that show that it regulates blood pressure, blood vessel constriction and the tendency of blood to form Clots). Its evaluation as an anticancer compound in the laboratory has been extensive, the extract showing weak activity in vitro and in vivo against standard tumor cell lines. The plant extract shows significant anti-inflammatory activity.
Ayurvedic Applications
The best herb for blood purification; blood circulation, controls bleeding, mends broken bones, amenorrhea, cancer, cleanses and regulates liver, spleen, pancreas, and kidneys; diarrhea, dysentery, dysmenorrhea, edema, destroys kidney and gall stones, heart disease, hepatitis, herpes, jaundice, menopause, menorrhagia, painful menstruation, post partum uterus stimulation, paralysis, skin problems, tissue healing, traumatic injuries, skeletal disease, Kapha disorders, joint pain, rheumatoid arthritis, improves complexion and voice, helps destroy benign and malignant tumors.
DARU HALDI (Berberis aristata)
Family: Berberidaceae
Barberry Uses & Scientific Evidence For Today Barberry is used for treating gallbladder disease, heartburn and indigestion, and diarrhea. It is also used for treating dysentery and hepatitis. This herb can also be used to treat infections, eczema, parasites, psoriasis, and vaginitis. Barberry is known to decrease heart rate, slow breathing, and reduce bronchial congestion as well. Barberry has been used in treating colorectal cancer, liver cancer, strep throat, and toxic shock syndrome though there is no conclusive scientific evidence to support its effectiveness in treating those conditions. This herb is also a remedy that corrects liver function and promotes the flow of bile. In eye drops. Barberry works well for eliminating bloodshot eyes.
Medicinal properties The fruits of Berberis aristata DC. are given as a cooling laxative to children. The stem is said to be diaphoretic and laxative and useful in rheumatism. The dried extract of the roots is used as an application in ophthalmia. It is also an excellent medication in the case of sun-blindness The bark of its root is a \aluable medicine in intermittent and remittent fevers. The root is one of the few really good medicines in India. In its efficacy, it is almost equal to quinine and Warburg's tincture. It does not produce any bad effects on the stomach, the bowels, the brain and the organs of hearing (Watt. 1889). A very valuable preparation called rasaut is prepared from this plant. For preparing rasaut. the bark of the root and of the lower part of the stem is boiled in water, strained and evaporated till a semi-solid mass (rasaut) is obtained. Rasaut is fairly soluble in water. It is mixed with butter and alum, or with opium and lime-juice and is applied externally to the eyelids to cure ophthalmia and other eye diseases (Jain. 1968). It is also reported to be a mild laxative, a tonic and is useful in curing ulcers and fevers (Kirtikar and Basu, 1938; Uphof. 1968). Dastur (1962) has reported that the chief constituent of Berberis aristata DC. is barberine, which is a bitter alkaloid. According to him, rasaut is used as a purgative for children and as a blood-purifier, a tonic and a febrifuge. It is also given in diarrhoea, jaundice and skin diseases. A watery solution of this preparation is also used for washing piles. Oriental sores and glandular swellings. The extract is derived form the roots of Berberis aristata belonging to family Berberidaceae. This Indian herb is been used as a Hepatoprotective and Anti-tumor. It is also been traditionally used as an emmenagogue. cholagogue, anli-arhythmic. anti-hypertensive. blood purifier, bitter tonic, stomachic and antiperiodic. The chief constituent of Berberis aristata is an alkaloid Berberine which is reported to be responsible for hepatoprotective activitv of Berberis aristata.

Scientific Evidence In clinical and preclinical studies, Berberis aristata has shown to have a liver protective property. In one of the scientific investigation, pretreatment of animals with berberine (4 mg/kg; orally twice daily for 2 days) not only prevented the acetaminophen or CC14 (hepatotoxic drugs) induced rise in serum levels of alkaline phosphatase (ALP) and aminotransaminases (AST and ALT) but also provided significant protection against liver damage. The results of this study indicated the potential hepatoprotective property of berberine. The studies translating antitumor properties of Berberis aristata have been conducted. In one of these studies it has been proved that administration of berberine (0.5. 2.5 or 5.0 mg/kg) could reduce significantly the incidence of tumor in animals after an injection of 20-methylcholanthrene a tumor inducer and increased their life span compared with the control. Pharmacological studies have shown its usefulness in man}' disorders including sedative, antitumor, wound healing. The dried stem, root bark and wood are alterative, antiperiodic, deobstruent. diaphoretic, laxative, ophthalmic and tonic (bitter)[46, 61, 158, 194, 240]. An infusion is used in the treatment of malaria, eye complaints, skin diseases, menorrhagia. diarrhoea and jaundiee[240. 243]. Berberine. universally present in rhizomes of Berberis species, has marked antibacterial effects. Since it is not appreciably absorbed by the body, it is used orally in the treatment of various enteric infections, especially bacterial dysentery[218]. It should not be used with Glycyrrhiza species (Liquorice) because this nullifies the effects of the berberine[218]. Berberine has also shown antilumour activity[218].
Remedies For: Cholagogue, Hepatic. Anti-Emetic. Bitter, Laxative
Ayurvedic action: Diuretic, Antibilious, Refrigerant, Stomachic, Bitter Tonic. Antiperiodic. Alterative, Antipyretic Used for the treatment as an antibiotic, immune stimulant, for treating pinkeye, high blood pressure. One study showed that the herb may shrink some tumors. Another study shoed that it has antiinflammatory properties, useful for treating arthritis. More work is needed in this case.
Indications : Barberry is one of the best remedies for correcting liver function and promoting the flow of bile. It is indicated when there is an inflammation of the gall-bladder or in the presence of gall stones. When jaundice occurs due to a congested state of the liver. Barberry is also indicated. As a bitter tonic with mild laxative effects, it is used with weak or debilitated people to strengthen and cleanse the system The herb is believed to have the ability to reduce an enlarged spleen. It acts against malaria. Herbalists recommend barberry as a stimulating tonic hepatic: influences the mucosa generally, removing mucoid accumulations and controlling excess secretion. Improves appetite, digestion and assimilation. Indicated for gouty constitutions. Felter considered barberry much like Hydrastis and could be employed for many of the uses of that scarce and high-priced drug.

Barberry tends to dilate the blood vessels, thereby lowering blood pressure. A teaspoon of the root will purge the bowels, or use an infusion of the berries with wine for the same purpose. A decoction of either berries or root bark makes a good mouthwash or gargle for mouth and throat irritations. The fresh juice of the fruit is also said to strengthen the gums and relieve pyorrhea when brushed on or applied directly to the gums.
Ayurvedic Applications For Bile And Urinary Conditions, Pitta Detoxification. And Congestion Of Abdomen And Pelvic Cavities; Rheumatism, Scarlet Fever. Brain Disorders, Heat, Thirst, Nausea; Small Amounts- Tonic; Large Doses-Purgative; Excellent Herb For Jaundice, During Pregnancy, Mild Laxative. Periodic Neuralgia. Fevers, Skin Diseases, Vomiting In Pregnancy; Fruit-Mild Laxative/Purgative For Children, Fevers, Blood Purifier. Malaria, Gastric And Duodenal Ulcers; Sores. Jaundice, Enlarged Liver And Spleen, And Regulates Liver Functioning. Diabetes. And Toxins/Ama (With Twice As Much Turmeric): Destroys Toxins. Reduces Body Fat (With Turmeric); Renal Calculi, Abdominal And Pelvic Congestion; G.l. Stimulant. Reduces Blood Pressure.
Common name: Flame of the Forest • :Palash Dhak . Tesu
• Pangong • Palas Botanical name: Butea monosperma Family: Fuhucccic (pea family) Synonyms: Butea frondosa. Erythrina monosperma, Plaso monosperma
Nati\e to India. Flame of the Forest is a medium sized tree, growing from 20 to 40 feet high, and the trunk is usually crooked and twisted with irregular branches and rough, grey bark. The leaves are pinnate, with an 8-16 cm petiole and three leaflets, each leaflet 10-20 cm long. The hindi phrase □□□ □□□ □□□ □□□ {"Dhaak ke teen paat") comes from the prominent three leaflets of this tree. It is seen in all its ugliness in December and January when most of the leaves fall: but from January to March it truly becomes a tree of flame, a riot of orange and vermilion flowers covering the entire crown. These flowers, which are scentless, are massed along the ends of the stalks—dark velvety green like the cup-shaped

calices~and the brilliance of the stiff, bright flowers is shown off to perfection by this deep, contrasting colour. Each flower consists of five petals comprising one standard, two smaller wings and a very curved beak-shaped keel. It is this keel which gives it the name of Parrot Tree. In olden days, the flowers of Tesu were used to make color for the festival of Holi. In Manipur. there is an interesting cultural use of the wood of this tree with beautiful flowers - when a member of the Meitei community dies and, for some reasons, his body cannot be be found, the wood of this tree is cremated in place of the body. A postal stamp was issued by the Indian Postal Department to commemorate this flower.
Antibacterial activity of aqueous extract of flowers of butea frondosa koen ex roxb (palas) is well known. The seeds are reported to be beneficial in the treatment of certain skin diseases. The seeds, ground and mixed with lemon juice, can be daubed on dhobi's itch-an eczema-type of skin disorder, characterized by itching. The\ can also be applied with gratifying results on ringworms. A hot poultice of the leaves can be applied to resolve boils, pimples, tumorous piles, ulcers and swellings. The crushed seeds can be used for killing maggots in wounds and sores.
Aloe Vera
Family: Asphodelaceae Species: Aloe vera
It's been known throughout history to have medicinal properties, used to cure various ailments and nowadays, the myths surrounding it that go back 5,000 years to the ancient Chinese, Egyptians and Greeks are no longer myths but medical fact. Scientists have found that the Aloe Vera gel is a mixture of antibiotic, astringent, coagulating agent, pain inhibitor, cell growth stimulator and scar " including most vitamins including B12, minerals, enzymes, protein and amino acids. What does all that mean you wonder - it's good for sunburn.
Scientific evidence for the cosmetic and therapeutic effectiveness of Aloe vera is limited and when present is typically contradictory. Despite this, the cosmetic and alternative medicine industries regularly make claims regarding the soothing, moisturising and healing properties of Aloe vera, especially via Internet advertising. Aloe vera gel is used as an ingredient in commercially available lotion, yogurt, beverages and some desserts. Aloe vera juice is used for consumption and relief of digestive issues such as heartburn and irritable bowel syndrome. It is common practice for cosmetic companies to add sap or other derivatives from Aloe vera to products such as makeup, tissues, moisturizers, soaps, sunscreens, incense, razors and shampoos. Other uses for extracts of Aloe vera include the dilution of semen for the artificial fertilization of sheep, use as fresh food preservative, and use in water conservation in small farms.
Aloe vera has a long association with herbal medicine, although it not known when its medical applications were first discovered. Early records of Aloe vera use appear in the Ebers Papyrus from 16th century BCE, in both Dioscorides' De Materia Medica and Pliny the Elder's Natural History written in the mid-first century CE[15] along with the Juliana Anicia Codex produced in 512 CE. Aloe vera is non-toxic, with no known side effects, provided the aloin has been removed by processing. Taking Aloe vera that contains aloin in excess amounts has been associated with various side effects. However, the species is used widely in the traditional herbal medicine of China. Japan. Russia, South Africa, the United States. Jamaica and India.
Aloe vera is alleged to be effective in treatment of wounds. Evidence on the effects of Aloe vera sap on wound healing, however, is limited and contradictory. Some studies, for example, show that Aloe vera promotes the rates of healing, while in contrast, other studies show that wounds to which Aloe vera gel was applied were significantly slower to heal than those treated with conventional medical preparations. A more recent review (2007) concludes that the cumulative evidence supports the use of Aloe vera for the healing of first to second degree burns. In addition to topical use in wound or burn healing, internal intake of Aloe vera has been linked with improved blood glucose levels in diabetics, and with lower blood lipids in hyperlipidaemic patients, but also with acute hepatitis (liver disease). In other diseases, preliminary studies have suggested oral Aloe vera gel may reduce symptoms and inflammation in patients with ulcerative colitis. Compounds extracted from Aloe vera have been used as an immunostimulant that aids in fighting cancers in cats and dogs; however, this treatment has not been scientifically tested in humans. The injection of Aloe vera extracts to treat cancer has resulted in the deaths of several patients.
Topical application of Aloe vera may be effective for genital herpes and psoriasis. However, it is not effective for the prevention of radiation-induced injuries. Although anecdotally useful, it has not been proven to offer protection from sunburn or suntan. In a double-blind clinical trial the group using an Aloe vera containing dentifrice and the group using a fluoridated dentifrice both demonstrated a statistically significant reduction of gingivitis and plaque. Aloe vera extracts have antibacterial and antifungal activities, which may help in the treatment of minor skin infections, such as boils and benign skin cysts. Aloe vera extracts have been shown to inhibit the growth of fungi that cause tinea; however, evidence for control beneath human skin remains to be established. For its antifungal properties. Aloe vera is used as a fish tank water conditioner. For bacteria, inner-leaf gel from Aloe vera was shown to inhibit growth of Streptococcus and Shigella species in vitro. In contrast. Aloe vera extracts failed to show antibiotic properties against Xanthomonas species.
Yarn Preparation
The composition of fabric is formed, in a first cellulose activation step, by chemical reaction between a hydroxyl group of the cellulose and a first functional group of bifunctional ligand to link the latter to the cellulose via a covalent bond and a second step, wherein a bioactive extract of medicinal plants which contains a functional group capable of reaction with the second functional group of said bifunctional ligand, is chemically reacted with, attached and bonded to the fungicidally extract of medicinal plants by reaction between the functional group constituting a component of said fungicidally active phenolic compound and the second functional group of said cellulose-ligand. Thus in a cellulose activation step, a bifunctional ligand is attached to the cellulose via reaction between one of
the functional groups of the bifunctional ligand and the hydroxyl substituents of the cellulose, the cellulose forming a matrix to which is attached the ligand which yet contains an unreacted functional group. A fungicidallv active extract of medicinal plants, which contains or to which is added a functional group reactive with the unreacted functional group of the ligomer of the cellulose-ligomer complex, is then reacted in a second step with the cellulose-ligomer complex to link the fungicidally extract of medicinal plants to the cellulose. Cellulose fibers, or yarns treated in this manner can then be processed finished articles of clothing, made from cellulose fibers, or yarns can be chemically treated in such manner and the fungicidally extract of medicinal plants bonded thereto such that the medicinally treated articles of clothing can be worn and employed for effective treatment of the areas of infected skin in contact with the clothing. The cellulosic textile material, after the reaction, retains substantially all of the textile properties characteristic of the untreated cellulose textile material, and retains the uses of the original cellulosic textile material. The hand, feel and appearance remain essentially the same. A yarn, e.g.. retains the physical properties of a yarn and can be woven into a fabric. A fabric so-treated retains the phy sical properties of the original fabric, and can be cut and the parts sewed together to form an article of clothing, and clothing so-treated will remain useful for their original purpose. All after treatment, however, will additionally be suitable as a drug for the treatment of those skin diseases for which the drug bonded to the cellulosic textile material was originally suitable. Preferred articles of medicated clothing are thus those worn in contact with areas of the skin likely to be infected.
The first step in the preparation of the composition of fabric in this invention is to activate the cellulose by attaching a suitable ligand to the cellulose material, suitably a cellulosic fiber, yarn, fabric or article of manufacture produced from
such textile materials, preferably a underwear. this providing the structural unit to which a derivative of the drug, or medicinal can be attached.
The compositions, or articles of manufacture, of this invention can be provided and applied in essentially any shape or form, and can be formed from a cellulose textile material of virtually any shape or form. Suitably, the composition or article of manufacture of this invention, is formed from a cellulose textile material, e.g.. a fiber, or material shaped as a yarn, or fabric. A cellulosic textile yarn can thus be treated in accordance with the technique described, the yarn then formed into a fabric, and a bandage or an article of clothing, e.g., a sock, then made from the fabric. On the other hand, a cellulose textile fabric can be so treated, and an article of clothing made from the treated fabric; or, the fabric can be made into an article of clothing, e.g., a sock, and the article of clothing treated in accordance with the process of this invention.
EXAMPLE
Optimum extraction condition for the extraction of bioactive material from
Manjishtha, Alovera , Palas (Tesu) Daru haldi
Selection of solvent
Selection of solvent including methanol, acetone.2-
propanol.dichloroethane.diethyl ether, ethyl acetate ,chloroform ,hexane and
water was carried out according to different functional groups. 10g of each whole
herb were soaked in 100 ml of respective solvent at 25 °C for 24 hours.
Maximum Amount of Dye Extracted
Optimum dye extraction was determined by extraction various amount of bioactive material from Manjishtha, Alovera , Palas (Tesu) Daru haldi , i.e.5, 10. 20, 30 g, respectively, in 100ml of water at 100° C for 90 min.
Optimum Temperature
Optimum temperature for dye extraction was determined by extracting 20g of bioactive material in 100ml of solvent at different temperatures, i.e.25. 50. 75 and 100° C, respectively, for 90 min.
Optimum Time
Optimum time for dye extraction was determined at 100° C by extraction 20g of dye in 100ml of solvent for different time intervals,i.e.5.10.20,30,60,90,120 and 180 min. .respectively .The amount of dye extracted under different conditions was measured by spectrophotometer at 420nm.
Treatment of fiber :- The root bark leaf,fruit and flower extract of Manjishtha, Alovera , Palas (Tesu) Daru haldi ( each 100 g) was dissolved in water (1000 ml), and cotton (5 g) was added. The bath was heated from 30° C.-90° C.
over 1 hour and sodium sulphate (0.750 g) was added. After a further 30 minutes, plant pulp was added and the dye bath heated at 90° C. for 1 hour.
According to the objective of the invention the process for making the fabric of the present invention entails steps which are substantially similar to current conventional processes for producing cotton, with the exception that the cellulose material used in the process of making the fiber in the present invention is a Manjishta, Alovera , Palas (Tesu) Daru haldi pulp.
In the present invention textiles was formed by weaving, knitting, crocheting, knotting of Mamishtha, Alovera , Palas (Tesu) Daru haldi plant cellulose pressing together.
Before the spinning step, the wood pulp was mixed with cotton fibers. A preferred mixture is one in which the different fibers exist in a proportionate ratio of 2%-5% of each .Manjishtha, Alovera , Palas (Tesu) Daru haldi fibers and 80% cotton fibers.
The fibers produced by the present invention have high strength, especially when wet. and good dimensional stabillity and firmness. In addition, the fibers produced by the process of the invention are highly absorbent
The fibers which result from the process of the present invention will be used in the manufacture of clothing, as medical fabrics.
Coating is a common technique used to apply dye particles onto textiles. The coating compositions that can modify the surface of textiles are usually composed
of micro-particles, a surfactant, ingredients and a carrier medium. Several methods can apply coating onto fabrics, including spraying, transfer printing, washing, rinsing and padding. Of these methods, padding is the most commonly used. The nano-particles are attached to the fabrics with the use of a padder adjusted to suitable pressure and speed, followed by drying and curing.
Coating enhance and extend the range of functional performance properties of textiles and the use of this techniques is growing rapidly as the applications for technical textiles become more diverse. Coating is a process in which a polymeric layer is applied directly to one or both surfaces of the fabric
• Coating can mostly be used of products which having capacity to convert in viscose liquid form. This viscose liquid so easily can spread over the surface and form coating.
• Drying or curing process which hardens the coating to produce a non blocking product.
• Due to viscosity requirement it is limited to linear polymers, which can be coated as a polymer melt or solution and on cooling, form a solid film or form solid film on evaporation of the solvent.
• There are some types of coatings that can be applied in the liquid form and then chemically cross-linked to form a solid-film.
In the present invention a bioactive functional material from plants Manjishtha, Alovera, Palas (Tesu) Daru haldi were coated as monofilament that forms coated fabric without losing the fabric's texture. The exhausted dye bath was completely colourless and the cloth was dyed in a shiny green shade with excellent wash-fastness.
Examples
Example -1 Bioactive functional material from plants Manjishtha, Alovera , Palas (Tesu) Daru haldi were coated as per heavy-duty technical textile coating 700 gm bioactive functional material was applied onto the fabric
Example -2 Three layers of bioactive functional material was applied
Example -3 In the present invention we developed a nano-scale processing technology that allows molecular arrangement and molecular self-assembly necessary to bring out further advanced functionalities in textile processing than the existing dyeing processing.
Example -4 Natural dyes obtained from the root bark and flowers of the Palas (Tesu) and Daru haldi have yellow to orange colorant that is substantially free of alkaloids and polyphenoloxidase. has good stability, minimal aroma, and does not contain any organic solvent residuals is provided.
Example -5 The natural colorant has a have yellow to orange equivalent to the other synthetic colorant and is more stable as compared to existing natural colorants. Methods for extracting dyes from Palas (Tesu) and Daru haldi has minimum use of an organic solvent, while essentially eliminating skin irritating polyphenoloxidase from the extract are also provided. Manjishtha and Alovera , was pressed and filtered and the filtrate is concentrated.
Example -6 The pH of the concentrate is adjusted with alkali to precipitate alkaloids therein. The concentrate is filtered and the pH of the filtrate is adjusted to a pH value of about 3.5 or lower. The pH is adjusted in such a manner to obtain a colorant having the desired yellow to orange color.
Example -7. The finished fabric samples have been tested for the specific activity related with the disease by in-vitro trials. The natural dye treated fabrics was exhibited significant prevention and treatment of skin problems.
Example -8. The wash durability of the treated sample was found good even after 50 wash. The principle for therapeutic value of textile is the rubbing fastness of medicinal plant active ingredients and trans dermal application. The beneficial aspects of the medicinal plant dyes in comparison to any of the synthetic dyes are high. Chemically created colors are terrible poisons.
Example -9. The finished fabric samples was exhibits an eco friendly properties which is organic and 100 % natural, which colored and coated by accurate and specified medicinal plants describes in Ayurvedic text for the prevention and treatment of Skin diseases. Some selective species of medicinal plants were identified and screened for their activity and the extracts were applied to cotton fabrics.
Example -10. The finished fabric samples were exhibits the prevention and treatment of Skin diseases described in Ayurvedic text.
Example -11. Clinical stud) was conducted to test the efficacy of medicated cloths was done at Clinical research centre of Patanjali. Clinical Research Centre of Patanjali undertook a six-month clinical trial at on patients suffering from type -1
Diabetes. For the study, all clothes, bed linens and mattresses of the patients were uniformly coated and d\ed in nano-scale sizes by the bioactive material from the plants Manjishtha, Alovera , Palas (Tesu) Dam haldi. The significant improvements in the health of patients suffering from Skin diseases were exhibit.
Those skilled in the art will appreciate that various adoptions and modifications of the just-described preferred embodiments can be configured without departing from the scope and spirit of the invention. Therefore, it is to be understood that, within the scope of the appended claims, the invention may be practiced other than as specifically described herein.
The following description is provided to enable any person skilled in the art to make and use the invention and. with reference to the drawings, sets forth the best mode contemplated by the inventor of carrying out this invention.
Various modifications, however, will remain readily apparent to those skilled in the art. since the generic principles of the present invention have been defined herein specifically to provide an improved fabric made entirely of plant materials, and which exhibits high absorbency. abrasion resistance, and tensile strength.

What it claimed is:
1. Therapeutic clothing comprising an Organic fabric whose dye with natural colour which have a therapeutic property for the prevention and treatment of Skin diseases.
2. The therapeutic clothing claim 1 where the fabric is selected from the clothing that is made from materials that was grown without the use of synthetic chemicals such as pesticides -herbicides or other chemicals.
3. The therapeutic clothing of claim 2 where the fabric is cotton, silk and wool.
4. The therapeutic clothing claim 1 where the therapeutic agent for the prevention and treatment of Skin diseases is the natural colour obtained from the Fruits, Leaves, stem and bark of the different species of Rubiaceae Berberidaceae, Fabaceae family,
which include Butea monosperma (Palash), Rubia cordifolia (Manjistha), Berberis aristata (Dam haldi).
5. The product of claim 1 where the entire ingredient claimed as therapeutic agent for the dyeing of organic fiber and cloths was tested for their efficacy by various in-vivo and in-vitro clinical trail the results was very significant on prevention and treatment of Skin diseases.
6. The in-vivo and in-vitro clinical trail claim 7 where the skin irritation patch test and other clinical test for dermal irritation were used for measuring the activity of ingredient claimed for the treatment and prevention of skin disease.
7. A method of making an therapeutic product comprising contacting a fabric dye and treated with an natural colors and other active ingredients from the various parts of the plant Butea monosperma (Palash), Rubia cordifolia (Manjistha), Berberis aristata (Daru haldi).