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Novel Therapeutic Composition For Dermatitis

Abstract: The present invention relates to a composition comprising of steroid and bioenhancer for treating various skin disorders like dermatitis, eczema, psoriasis, etc wherein bioenhancer enhances bioavailability of the steroid by enabling significant improvement in skin penetration of steroid, resulting in high therapeutic efficacy of the composition as well as reducing the side effects and duration of therapy.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
29 May 2012
Publication Number
29/2017
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
Parent Application

Applicants

CURATIO HEALTHCARE PVT LTD
78/88, DEFENCE OFFICER'S COLONY, NANDAMBAKKAM, CHENNAI - 600 032

Inventors

1. NARASIMHAN JAY KAUSHIK
C/O CURATIO HEALTHCARE PVT LTD., 78/88, DEFENCE OFFICER'S COLONY, NANDAMBAKKAM, CHENNAI - 600 032

Specification

DESC:As attached ,CLAIMS:1. A therapeutic composition for chronic skin diseases comprising a steroid agent as an active ingredient and a bioenhancerdiffused in hydrogel base to enhance the bioavailability of the said steroid thereby increasing the therapeutic efficacy of the said composition and deeply hydrate the affected skin which ensures reductionin the duration of the therapy with minimal side effects.

2. The therapeutic composition for chronic skin diseases according to claim 1, wherein the steroid agent is Corticosteroids and its pharmaceutically acceptable ester thereof in any chiral form or mixture.

3. The therapeutic composition for chronic skin diseases according to claim 1, wherein the bioenhancer is Tetrahydropiperine, methylsulfonylmethane (MSM), curcumin, glycyrrhizin or allicin thereof.

4. The therapeutic composition for chronic skin diseases according to claim 1, wherein the said composition is selected from the group consisting of creams, gel, lotion or ointment.

5. The therapeutic composition for chronic skin diseases according to claim 1 and claim 2, wherein the concentration of steroid is about 0.01% w/w and 5%w/w.

6. The therapeutic composition for chronic skin diseases according to claim 1 and claim 3, wherein the concentration of bioenhancer is about 0.1%w/w and 10%w/w.

7. The therapeutic composition for chronic skin diseases according to claim 1, wherein the said composition is administered topically.

8. The therapeutic composition for chronic skin diseases according to claim 1 to 6, wherein the chronic skin disease is a disease selected from the group consisting of dermatitis, eczema, psoriasis, urticaria and melasma.

9. The therapeutic composition for chronic skin diseases according to claim 1, wherein the whole of the composition is stable for eighteen months when the composition is subjected to stability studies.

10. The therapeutic composition for chronic skin diseases according to claim 1, wherein the whole of the composition could reduce the severity of the disease within 2 weeks of use when the composition is subjected to clinical studies.

Documents

Orders

Section Controller Decision Date

Application Documents

# Name Date
1 2148-CHE-2012 POWER OF ATTORNEY 29-05-2012.pdf 2012-05-29
1 2148-CHE-2012-US(14)-HearingNotice-(HearingDate-14-09-2020).pdf 2020-08-11
2 2148-CHE-2012-CLAIMS [20-06-2018(online)].pdf 2018-06-20
2 2148-CHE-2012 FORM-2 29-05-2012.pdf 2012-05-29
3 2148-CHE-2012-FER_SER_REPLY [20-06-2018(online)].pdf 2018-06-20
3 2148-CHE-2012 FORM-1 29-05-2012.pdf 2012-05-29
4 2148-CHE-2012 DESCRIPTION (PROVISIONAL) 29-05-2012.pdf 2012-05-29
4 2148-CHE-2012-OTHERS [20-06-2018(online)].pdf 2018-06-20
5 2148-CHE-2012-FER.pdf 2017-12-20
5 2148-CHE-2012 CORRESPONDENCE OTHERS 29-05-2012.pdf 2012-05-29
6 Form 5.pdf 2013-05-31
6 Complete Specification.pdf 2013-06-17
7 2148-CHE-2012 FORM-3 31-05-2013.pdf 2013-05-31
7 2148-CHE-2012 CORRESPONDENE OTHERS 31-05-2013.pdf 2013-05-31
8 2148-CHE-2012 FORM-3 31-05-2013.pdf 2013-05-31
8 2148-CHE-2012 CORRESPONDENE OTHERS 31-05-2013.pdf 2013-05-31
9 Form 5.pdf 2013-05-31
9 Complete Specification.pdf 2013-06-17
10 2148-CHE-2012 CORRESPONDENCE OTHERS 29-05-2012.pdf 2012-05-29
10 2148-CHE-2012-FER.pdf 2017-12-20
11 2148-CHE-2012 DESCRIPTION (PROVISIONAL) 29-05-2012.pdf 2012-05-29
11 2148-CHE-2012-OTHERS [20-06-2018(online)].pdf 2018-06-20
12 2148-CHE-2012-FER_SER_REPLY [20-06-2018(online)].pdf 2018-06-20
12 2148-CHE-2012 FORM-1 29-05-2012.pdf 2012-05-29
13 2148-CHE-2012-CLAIMS [20-06-2018(online)].pdf 2018-06-20
13 2148-CHE-2012 FORM-2 29-05-2012.pdf 2012-05-29
14 2148-CHE-2012-US(14)-HearingNotice-(HearingDate-14-09-2020).pdf 2020-08-11
14 2148-CHE-2012 POWER OF ATTORNEY 29-05-2012.pdf 2012-05-29

Search Strategy

1 2148_19-12-2017.pdf