The present invention relates to nutraceutical bar dosage form, and process of preparation thereof.
Ayurveda believes that the 'Rasayanas' are meant to impart long, healthy, disease free life and intelligence. 'Rasayana' aims at maintaining youthfulness, vigour, vitality of the body and keeping away ageing process, senility and debility by maintaining the proper functioning of the cells and rejuvenating the cells. Several recipes for rasayana are presented in Charaka Samhita, which are based on the use of one or more of the three myrobalans fruits (a simple rasayana, triphala, is made by combining all the three). Chyawanprash, is however one of the complex and foremost of all the rasayanas, and especially good for alleviating cough and asthma, its use imparts intelligence, memory, calmness of body, freedom from disease, longevity, strength of the senses, improved digestion and improved complexion. Further it helps in preserving the harmony of the three doshas. Apart from Charaka Samhita, the other formulation details of chaywanprash are disclosed in Bhaishayja Ratnavali, Sharangadhara-Samhita and Ayurvedic formulary.
As per the 2,000 year old recipe from the Charaka Samhita, Chyawanprash, is a mix of 49 powerful ayurvedic herbs with 'amla1 (Indian gooseberry) as the base. Today, there are many commercially available recepies for Chyawanprash, ranging in ingredients from a mere 20 or so herbs and spices to 70 or 80 ingredients. These include Himani Sona Chandi Chyawanprash, Dabur Chyawanprash, Baidyanath Chyawanprash, Zandu Chyawanprash, Zandu Kesari Jivan, Maharishi Ayurveda Amrit Kalash, Maharishi Ayurveda Chyawanprash, Jeevan-Anand Chyawanprash, Baidyanath Kesri Kalp Chyawanprash, Dabur Chyawanshakti and Himani Sona Chandi Amritprash. As all these have a classical 'jam' or a 'sticky paste' like consistency and a sharp bitter taste with a tinge of sourness, there remains a need for other consumer compliant dosage forms. Chyawanprash tablets, Sugar free Chyawanprash capsules (Pravek Prash®) and Chyawanprash bars (Herb-All™) are available in the market. But as taste and appearance remain the key factor for driving the acceptability of the consumers, out of all these, bar remains the most popular dosage form. Hence there remains a need to formulate consumer compliant Chyawanprash bar dosage form using a novel process so as to provide an alternative for the formulators. Further there remains a need to formulate sugar free Chyawanprash bar dosage form for special group of diabetics and health conscious people.

We have developed an alternative process of preparing Chyawanprash bar dosage form in order to meet the required taste and appearance characteristics, thus making the dosage form more consumer compliant. Further we have also developed Chyawanprash bar dosage form for special group of diabetics and health conscious people.
Hence in one general aspect there is provided a process of preparing a nutraceutical bar dosage form, wherein the process comprises the steps of;
(a) preparing Pradhana Dravya, Samsadhana Dravya, Prakshep Dravya;
(b) mixing syrup ingredients with Pradhana Dravya, Samsadhana Dravya,
Prakshep Dravya, and heating;
(c) applying vacuum to evaporate water, and
(d) cooling and formulating the mass into bars.
In another general aspect there is provided a process of preparing Pradhana Dravya, wherein the process comprises the steps of;
(a) cooking the amla fruits under steam,
(b) removing the seeds to obtain pulp, and
(c) frying the pulp with Yamaka Dravya to obtain the thick paste.
In another general aspect there is provided a process of preparing Samsadhana Dravya, wherein the process comprises the step of extracting the herbs in the crude/powder form with a suitable solvent.
In another general aspect there is provided a process of preparing Prakshep Dravya, wherein the process comprises the steps of;
(a) powdering the herbs, shrubs or spices, optionally sieving,
(b) blending, and
(c) mixing the powder blend of step (b) with one or more sweeteners.
In another general aspect there is provided a sugar free nutraceutical bar dosage form comprising one or more non-sugar sweeteners.
In another general aspect there is provided a sugar free nutraceutical bar dosage form, comprising Pradhana Dravya, Samsadhana Dravya, Prakshep Dravya, Yamaka Dravya and syrup ingredients, wherein the Prakshep Dravya comprises one or more non-sugar sweeteners.
In another general aspect there is provided a process of preparing a sugar free nutraceutical bar dosage form, wherein the process comprises the steps of;
(a) preparing Pradhana Dravya, Samsadhana Dravya, Prakshep Dravya;
(b) mixing syrup ingredients with Pradhana Dravya, Samsadhana Dravya, Prakshep
Dravya, and heating;
(c) applying vacuum to evaporate water, and
(d) cooling and formulating the mass into bars,
wherein the Prakshep Dravya comprises one or more non-sugar sweeteners.
Chyawanprash or Chyavanprasha or Chyavanprash or Chyawanaprash, is an ancient Ayurvedic health tonic, widely used in India, as a rejuvenative, energizer and immunity booster. This magic elixir is good for all, irrespective of age and gender, and creates a harmonious synergy in the body leading to the better metabolism. It is one of the elaborate ayurvedic products which is indicated for general disorders, and can be useful to people of the different doshic types, and of various origins. The age-old Chyawanprash is regarded as an all-embracing herbal health tonic by one and all, and has become an indispensable part of a healthy family. Chyawanprash offers anti-stress and antioxidant benefits. Chyawanprash's basic ingredient, amla is a rich source of vitamin C and helps in strengthening the immune system and expediting the healing process. Regular intake of Chyawanprash strengthens digestion, absorption and assimilation of food and thus balances stomach acids. This perfect blend of Ayurvedic herbs acts as a cardiac stimulant and helps in smooth functioning of the heart. Chyawanprash further nourishes the brain cells by supporting the nervous system and enhances co-ordination and memory power. The regular intake of Chyawanprash maintains the moisture balance in the lungs and gives new energy to respiratory system. Chyawanprash helps to purify blood by eliminating toxins. Apart from these, it eliminates wastes from the body without overloading the urinary system. The holistic traditional formula of Chyawanprash improves skin complexion, glow and fights dermal bacterial infection. It promotes hair growth and helps absorption of calcium resulting in strong bones and teeth. It is especially good for alleviating cough and asthma. The anti-
oxidant properties of the tonic act against the ageing process and maintain youthfulness. Chyawanprash enhances fertility, keeps menstruation regular and helps to overcome difficulties in conception. It also improves muscle tone by enhancing protein synthesis effectively. Also, Chyawanprash has a potent free-radical scavanging effects, prevents carcinogenesis and mutagenesis, and boosts the immune system in patients undergoing chemotherapy. Chyawanprash plays an important role in balancing the three doshas i.e. Vata (air), Pitta (fire) and Kapha (water), especially preserving the harmony of the Vata dosha, which according to Ayurveda is the underline cause of diabetes or Madhumeha. It is also used to dispel drowsiness and fatigue, and general weakness in a patient suffering from diabetes.
Chyawanprash in the form of a bar dosage form, offers all the advantages of solid dosage form over semi-solid dosage form. As being more compact, these are easy to handle, easy to transport, easy to store, and more importantly offers ease in consumption as these could be taken anywhere anytime. Also, bars being solid dosage forms, and individually packed, the chances of contamination are negligible. Also these may be consumed by hand without leaving substantial residues on the hands or other surfaces to which it comes into contact. Further the key benefit remains for the children for whom these bars could be placed in their lunch boxes, thus breaking the home consumption barrier and allowing them to have it whenever wanted. Additionally the dosage form in the form of bars, enhances the aesthetic appeal and thus overall makes the dosage form more consumer compliant over the classical paste Chyawanprash
The nutraceutical bar dosage form, of the present invention may comprise Pradhana Dravya, Samsadhana Dravya, Yamaka Dravya, Prakshep Dravya, and syrup ingredients.
The term 'Pradhana Dravya' as used herein describes the primary ingredient of the composition and is represented by Amla, also known as amalaki or a tropical gooseberry or Indian thorny currant or Emblica officinalis (Euphorbiaceae), the fruit pulp being the main part used. The 'Amla' may be selected from any form of amla such as amla pishty, amla pulp, fried amla pulp, amla powder, in particular amla pishty. The amla pishty means amla paste or any thick viscous composition of amla. Amla is preserved by an ayurvedic technique of development using lipids to form a paste; the
preserved amla is then further cooked with other ingredients to form a nutraceutical composition.
The term 'Samsadhana Dravya' as used herein includes various herbs with specific medicinal properties based on specific marker compounds present in them. The herbs may be used in the form of an extract or a powder, in particular extract. The extract, if used, may be aqueous or organic solvent extract, in particular aqueous extract. The herbs may be used in equal quantities to form the Samsadhana Dravya.
The herbs used to prepare the Samsadhana Dravya may include any herb which may have pharmacological activities such as memory enhancer, antioxidant, anti-depressant, immuno-modulator, adaptogen and health promoter. The herbs may include, but not limited to, Vanshlochan or Bangsolochan or Bambusa arundinacea (Gramineae), Patala or Stereospermum suaveolens (Bignoniaceae), Arani or Agnimantha or Premna integrifolia (Verbenaceae), Gambhari or Gmelina arborea or (Verbenaceae), Bilva or Bel or Aegle marmelos (Rutaceae), Shyonaka or Syonaka or Oroxylum indicum (Bignoniaceae), Gokshura or Gokhru or Tribulus terresteris (Zygophyllaceae), Shalaparni or Salparni or Desmodium gangeticum (Leguminosae), Brahati or Brihati or Solanum indicum (Solanaceae), Kantakari or kantkari or Solanum xanthocarpum (Solanaceae), Kakra-shringi or Pistacia integerrima/Rhus succedanea (Anacardiaceae), Draksha or Grapes or Vitis vinifera (Vitaceae), Guduchi or Tinospora cordifolia (Menispermaceae), Haritaki or Terminalia chebula (Comretaceae), Bhuiamla or Bhumiamlaki or Phyllanthus niruri (Euphorbiaceae), Vasaka or Adhatoda vasica (Acanthaceae), Jeevanti or Jivanti, jiwanti or Leptadenia reticulate/Dendrobium macraei (Asclepiadaceae), Kachur or Curcuma zedoaria (Zingiberaceae), Nagarmothan or Mustak or Cyperus rotundus (Cyperaceae).Pushkara or Pishkarmool or Inula racemosa (Asteraceae), Mudgaparni or Phaseolus trilobus (Leguminosae), Mashparni or Termanus labialis (Fabaceae), Kakanasa or Asclepias curassavica/ Martynia diandra (Apocynaceae), Vidari or Ipomoea digitata (Convolvulaceae), Punarnava or Boerhavia diffusa (Nyctaginaceae), Kanwal or Lotusor Nelumbium speciosm (Aceraceae), Chandan or Santalum album (Santalaceae), Shatavari or Satavari or Asparagus racemosus (AsparagaceaeJ, Ashwagandha or Withania somnifera (Solanaceae), Prishparni or Uraria picta or Uraria lagopoides (Leguminosae), Varahikand or Bilaikand or Yam or Tacca aspera or Dioscorea bulbifera (Dioscoreaceae), Brahmi or Bacopa monnieri (Scrophulariaceae), Shankhapushpi or Evolvulus alsinoides (Convolvulaceae),
Bala or Khareti or Sida cordifolia (Malvaceae), Karkatshringi or Pistacia integerrima
(Pistaciaceae), Agar or Aquillaria agallocha (Aloeaceae), Vidarikand or Indian kudju or
Pueraria tuberosa (Leguminoseae), Shati or Hedychium spicatum, Ela
or badi ilayaci or bari ilachi or Amomum subulatum (Zingiberaceae), Neelkamal or Nymphaea nouchali/stellata (Nymphaeaceae), Kaknasa, Agnimantha or urni or Premna integrifolia/Clerodendron phlomoides (Verbenaceae), Bara Gokhru or Pedalium murex (Pedaliaceae).
The term 'Yamaka Dravya' as used herein describes the lipid part used to prepare the sugar free nutraceutical composition. The lipids may be selected from any of the fats, oils, waxes and phospholipids. Examples of fats include ghee, margarine, butter, cream, and the like, in particular ghee. Examples of oils include cottonseed oil, coconut fat, arachis oil, linseed oil, sunflower oil, soybean oil, olive oil, sesame oil, and the like, in particular sesame oil. Examples of waxes include lanolin, beeswax and the like. Examples of phospholipids include lecithin, in particular soya lecithin. Lipids can bind with lipid-soluble nutrients and helps to penetrate the lipid-based cell membranes of the body. It is thus used to increase the potency of certain herbs by carrying the active components to the interior of the cells where they impart their beneficial effects. The lipid part is mainly used to fry the ingredients to make a paste in order to preserve them.
The term 'Prakshep Dravya' as used herein describes the flavoring or seasoning agents which may have specific medicinal properties based on specific marker compounds present in them, in addition to their basic organoleptic properties. These may include flavoring or aromatic agents, sweetening agents, coloring agents, and texture forming agents. The herbs may be used in the form of an extract or a powder, in particular powder.
The flavoring/aromatic agents, also sometimes known as spices, may include any of the hebrs/medicinal plants containing the essential volatile components such as volatile oil to enhance the aroma of the composition. These may include, but not limited to Pipli or Pippali or Piper longum (Piperaceae), Kesar or Saffron or Kumkum or Crocus sativus (Iridaceae), Chhoti Elaichi or Elattaria cardamomum (Zigiberaceae), Dalchini orTwak or Cinnamomum cassia (Lauraceae), Tejpatra or Tamalpatra or Cinnamomum tamala (Lauraceae), Nagkesar or Mesua ferrea (Clusiaceae), Akarkara or Anacyclus pyrethrum
(Asteraceae), Betel or Piper betel (Peperaceae), Rasna or Pluchea lanceolata (Asteraceae), Clove or Syzygium aromaticum/Myrtus caryophyllus (Myrtaceae), Nilofar or Chota Kanwal or White Water-Lily or Nymphaea lotus (Nymphaeaceae), Turpentine, Juniper, Coriander, Otto of rose, Geranium, Sandalwod, Lavendar, Rosemary, Peppermint, Cinnamon bark, Cumin, Cassia, Lemon, Lemon grass, Spearmint, Caraway, Dill, Clove, Thyme, Ajowan, Horsemint, anise and star anise, Fennel, Eucalyptus, Cajuput, Camphor, Matricaria flowers, Chamomile flowers, Asafoetida, Parsley, Nutmeg, Curry leaves, Capers, Chenopodium, Mustrard, Wintergreen and bitter almond.
Examples of sweetening agents include, sugar sweetener or non-sugar sweeteners. The sugar sweeteners include, but not limited to glucose (liquid or solid), dextrose, honey, sucrose, fructose, lactose, maltose, glycerine, brown sugar, galactose, invert syrup, corn syrup (liquid or solids) such as high fructose corn syrup, and the like.
The term 'non-sugar sweeteners' as used herein means sweeteners having no refined sugar (sucrose) in them, and having a low glycemic response as compared to sugar (sucrose). These may also be known as sugar substitutes and include any non-sugar sweetener which is Generally Recognized as Safe (GRAS) by FDA for their use in the food products. These may be divided into natural and artificial non-sugar sweeteners. Examples of the natural non-sugar sweeteners include brazzein, curculin, miraculin, monellin, pentadin, thaumatin, fructose, glycyrrhizin, hydrogenated starch hydrolysates, fructo-oligo-saccharides (fructans, oligosaccharides, oligofructose and inulin), lactitol, mabinlin, maltitol, mannitol, inositol, erythritol, xylitol, sorbitol, stevia, tagatose and the like. Examples of the artificial non-sugar sweeteners includes saccharin, cyclamate, alitame, aspartame, sucralose, neotame and acesulfame potassium and its sodium and calcium salts, aspartame-acesulfame salt, neohesperidine dihydrochalcone, isomalt and the like.
The use of these non-sugar sweeteners is highly recommended for diabetics who have difficulty in regulating their blood sugar levels. As these metabolize slowly and undergo slow and incomplete absorption, the rise in blood glucose and insulin response associated with the ingestion of glucose, is significantly reduced when using these non sugar sweeteners as alternatives. Also for a diabetic patient, weight control along with the control of blood glucose is equally important for the management of diabetes. Since
the absorption of these non-sugar sweeteners is slow, only a portion of these reach the large intestine, where their metabolism yields only few calories. So the reduced calorie intake with these non-sugar sweeteners is consistent with the objective of weight control.
Further keeping in mind, today's life style where the people are having no time to exercise, but being health conscious, are trying to limit their food calorie intake. The sugar free nutraceutical bar dosage form could be a better choice for these groups of people who want to loose weight, or are health conscious to avoid problems associated with excessive energy intake.
The coloring agents may include any of natural color obtained form the plants selected from the group consisting of Dactylopius coccus, Beta vulgaris, Capsicum annum, Crocus sativus, Cartyamus tinctorius, Curcumin longa, Omosma echiodes, Rubia cord/folia, Pterocarpus santinus, Bixa orellena, Tagetes eretca, Monascus purpurea, Rosea gallica, Papaver rhoeas caramel color, kusum phool, japakusum, manjistha, ratanjyot and the like It may further include carotenes from carrot root and chlorophyll and complexes form leaves.
The texture forming agents may also be known as consistency or mouthfeel or body forming agents. Texture is the mingled experience derived from the sensations of the mucus membrane in the mouth during and/or after ingestion of a food or beverage. It relates to density, moisture, viscosity, surface tension and other physical properties of the food or beverage being taken. These may include any of the mulethi, vidarikand, draksha, varahikand, satawari, pectin, jivak, rishbhak, amla, maltodextrin, natural gums, cocoa, starch and its derivatives, skimmed milk powder such as milk solids, silicon dioxide and the like.
Sugar-free nutraceutical composition of the present invention may further include preservatives to preserve the composition. Examples of the preservatives include Sorbic acid and its salts, Acetic acid, propionic acid and its salts, benzyl alcohol, phenethyl alcohol, phenoxyethanol, benzoic acid and its salts, methyl paraben and its salts, propyl paraben and its salts, butyl paraben, ethyl paraben, propyl gallate, butylhydroxyanisole, butylhydroxytoluene, palmityl ascorbate, and the like.
The term 'syrup ingredients' as used herein includes any ingredient to provide the syrup like consistency which is required for formulating the dosage form into bars. Syrup ingredients may include components such as invert syrup, liquid glucose, sorbitol, mannitol, xylitol, maltitol, corn syrup, glycerine, lecithin such as soya lecithin, vegetable fat, glycerides such as glyceryl mono stearate and soybean oil or other liquid oils and the like.
Sugar free nutraceutical bar dosage form may further include any herbal ingredients used for the treatment of diabetes or Madhumeha. Examples of these herbal ingredients include, but not limited to, Gurmar leaves of Gymnema sylvestre, seeds of Methi or Trigonella foenumgrecum, heartwood of Vijayasar or Pterocarpus marsupium, seeds of Jamun or Eugenia jambolana, radix of Rehmannia glutinosa, radix of Astragalus membranaceus, radix of Pueraria lobata, radix of Trichosanthes kirilowii, rhizomes of Dioscorea opposite, stigma of Zea mays, fructus of Schisandra sphenanthera, Karela or Momordica charantia, Aegle marmelos, Allium cepa, Allium sativum, Annona squamosa and the like.
In one of the embodiment, the nutraceutical bar dosage form may be prepared by a process comprising the steps of;
(a) preparing Pradhana Dravya, Samsadhana Dravvya, Prakshep Dravya;
(b) mixing syrup ingredients and salt with Pradhana Dravya, Samsadhana Dravya,
Prakshep Dravya, and heating in a steam jacketed vessel at a elevated
temperature;
(c) applying vacuum to evaporate water,
(d) cooling and formulating the mass into bars.
In another embodiment, sugar free nutraceutical bar dosage form may be prepared by a process comprising the steps of;
(a) preparing Pradhana Dravya, Samsadhana Dravya, Prakshep Dravya;
(b) mixing syrup ingredients and salt with Pradhana Dravya, Samsadhana Dravya,
Prakshep Dravya, and heating in a steam jacketed kettle at a elevated
temperature;
(c) applying vacuum to evaporate water, and
(d) cooling and formulating the mass into bars,
wherein the Prakshep Dravya comprises one or more non-sugar sweeteners.
The elevated temperature may vary from up to 40°C to 120°C, in particular up to 60°C to 90°C.
The vacuum may be applied to evaporate water till moisture content is between 2-15%, in particular 3-8%.
The mass obtained from above processes could be formulated into bars using conventional techniques. The mass may be extruded onto a conveyor belt or transferred to a bar extruder, such as Werner-Lahara bar extruder, or may be cold-pressed by spreading the mixture onto a leveled surface and applying compression from above, such as by a mold or by pressure platen or fed through a roller and cut into predetermined shape and dimensions with a suitable cutter such as guillotine cutter or a wire cutter.
In another embodiment, Pradhana Dravya may be prepared by a process comprising the steps of;
(a) cooking the amla fruits under steam,
(b) removing the seeds to obtain pulp,
(c) frying the pulp with Yamaka Dravya to obtain the thick paste.
In another embodiment, Samsadhana Dravya may be prepared by a process comprising the step of extracting the herbs in the crude/powder form with a suitable solvent.
In another embodiment, Samsadhana Dravya may be prepared by a process comprising the steps of;
(a) powdering the herbs, optionally sieving and
(b) blending.
In another embodiment, Prakshep Dravya may be prepared by a process comprising the steps of;
(a) powdering the herbs, shrubs and spices, optionally sieving,
(b) blending, and
(c) mixing the powder blend of step (b) with one or more sweeteners.
In another embodiment, Prakshep Dravya may be prepared by a process comprising the steps of;
(a) extracting the herbs, shrubs and spices in the crude/powder form with a suitable
solvent,
(b) mixing the extract of step (a) with one or more sweeteners.
The solvent used for extraction of the herbs, shrubs and species of the present invention may be selected from the group consisting of water, acidulated water, ethanol, and the like, in particular water.
The extraction may be done by conventional processes such as decoction, infusion or maceration, in particular decoction.
The extract may comprise combination of individual extracts of herbs or the combined extract of herbs. The extract of the herbs, may be centrifuged or concentrated before use. The extract of the herbs may be concentrated under evacuated condition or at high temperature to such a consistency which may contain active constituents or their marker constituents in such a concentration or dose so as to show therapeutic effect on the consumer.
The plant parts used in the present invention includes tender parts such as roots, rhizomes, leaves, barks, fruits, flowers. The tender plant parts may be dried in shade at a temperature about 40-45°C before further processing and may be ground fine using conventional means such as milling, sieving.
The fruits may be ripened and used in the form of a pulp and the pulping may be done using conventional techniques. The fruits may be washed, peeled, cored and pitted before use.
The seed products may be selected from dried seeds, roasted seeds and powdered seeds.
The nutraceutical bar dosage form may be packaged, preferably in a conventional foil laminate food grade packaging film. Packaging in a foil laminate film preserves the
moisture content of the bar and prevents it from becoming dry and crumbly over an extended period of time. The interior of the package can be flushed with an inert gas, such as nitrogen, in conventional manner to reduce the oxygen content in the package.
The nutraceutical bars of the present invention may be further coated with a suitable flavored coating such as chocolate flavored, vanilla flavored, peanut flavored, coconut flavored, fruit flavored, milk chocolate flavored, yogurt flavored coating or the like using conventional techniques, such as enrobing, spraying or dipping.
The invention is further illustrated by the following examples, which is for illustrative purpose only and should not be construed as limiting the scope of the invention in any way
.(Table Removed)
Procedure:
1. Ingredients 1-34 were powdered and mixed.
2. Coarse powder mixture of step 1 was boiled with sufficient amount of water for
about two hours.
3. The step 2 was repeated and the decoction was collected.
4. Amla fruits were cooked under steam and seeds were removed to get the pulp.
5. The pulp of step 4 was fried with ghee and seasome oil to get a thick paste.
6. Kumkum was triturated with propylene glycol to make a paste.
7. Ingredients 39-45 were sifted through sieve #40 and mixed.

8. The sifted powder mixture of step 7 was mixed with kumkum paste of step 6 and
silicon dioxide.
9. Ingredients from 48-60 were mixed and heated up to a temperature of 85-90°C
using steam jacketed vessel.
10. The decoction of step 3 and paste of step 5 was added to mixture of step 9.
11. Vacuum was applied to evaporate water till moisture content is between 5-
10%w/w.
12. The mass obtained form step 11 was cooled and formulated into bars of desired
shape and size using appropriate tooling.

WE CLAIM:
1. A process of preparing a nutraceutical bar dosage form, wherein the process
comprises the steps of;
(a) preparing Pradhana Dravya, Samsadhana Dravya, Prakshep Dravya;
(b) mixing syrup ingredients with Pradhana Dravya, Samsadhana Dravya,
Prakshep Dravya, and heating;
(c) applying vacuum to evaporate water, and
(d) cooling and formulating the mass into bars.
2. The process of preparing nutraceutical bar dosage form of claim 1, wherein the
Pradhana Dravya comprises one or more of amla pulp, fried amla pulp and amla
powder.
3 The process of preparing nutraceutical bar dosage form of claim 1, wherein the Samsadhana Dravya comprises one or more of herbs having pharmacological activities, selected from the group consisting of Vanshlochan or Bangsolochan or Bambusa arundinacea (Gramineae), Patala or Stereospermum suaveolens (Bignoniaceae), Arani or Agnimantha or Premna integrifolia (Verbenaceae), Gambhari or Gmelina arborea or (Verbenaceae), Bilva or Bel or Aegle marmelos (Rutaceae), Shyonaka or Syonaka or Oroxylum indicum (Bignoniaceae), Gokshura or Gokhru or Tribulus terresteris (Zygophyllaceae), Shalaparni or Salparni or Desmodium gangeticum (Leguminosae), Brahati or Brihati or Solanum indicum (Solanaceae), Kantakari or kantkari or Solarium xanthocarpum (Solanaceae), Kakra-shringi or Pistacia integerrima/Rhus succedanea (Anacardiaceae), Draksha or Grapes or Vitis vinifera (Vitaceae), Guduchi or Tinospora cordifolia (Menispermaceae), Haritaki or Terminalia chebula (Comretaceae), Bhuiamla or Bhumiamlaki or Phyllanthus niruri (Euphorbiaceae), Vasaka or Adhatoda vasica (Acanthaceae), Jeevanti or Jivanti, jiwanti or Leptadenia reticulate / Dendrobium macraei (Asclepiadaceae), Kachur or Curcuma zedoaria (Zingiberaceae), Nagarmothan or Mustak or Cyperus rotundus (Cyperaceae).Pushkara or Pishkarmool or Inula racemosa (Asteraceae), Mudgaparni or Phaseolus trilobus (Leguminosae), Mashparni or Termanus labialis (Fabaceae), Kakanasa or Asclepias curassavica I Martynia
diandra (Apocynaceae), Vidari or Ipomoea digitata (Convolvulaceae), Punarnava or Boerhavia diffusa (Nyctaginaceae), Kanwal or Lotusor Nelumbium speciosm (Aceraceae), Chandan or Santalum album (Santalaceae), Shatavari or Satavari or Asparagus racemosus (AsparagaceaeJ, Ashwagandha or Withania somnifera (Solanaceae), Prishparni or Uraria picta or Uraria lagopoides (Leguminosae), Varahikand or Bilaikand or Yam or Tacca aspera or Dioscorea bulbifera (Dioscoreaceae), Brahmi or Bacopa monnieri (Scrophulariaceae), Shankhapushpi or Evolvulus alsinoides (Convolvulaceae), Bala or Khareti or Sida cordifolia (Malvaceae), Karkatshringi or Pistacia integerrima (Pistaciaceae), Agar or Aquillaria agallocha (Aloeaceae), Vidarikand or Indian kudju or Pueraria tuberosa (Leguminoseae), Shati or Kapur kachri or Hedychium spicatum, Ela or badi ilayaci or bari ilachi or Amomum subulatum (Zingiberaceae), Neelkamal or Nymphaea nouchali/stellata (IMymphaeaceae), Kaknasa, Agnimantha or urni or Clerodendron phlomoides (Verbenaceae), Bara Gokhru or Pedalium murex (Pedaliaceae).
4. The process of preparing nutraceutical bar dosage form of claim 1, wherein the
Yamaka Dravya comprises one or more of ghee, margarine, butter, cream,
cottonseed oil, arachis oil, linseed oil, sunflower oil, soybean oil, olive oil,
sesame oil, lanolin, beeswax and lecithin.
5. The process of preparing nutraceutical bar dosage form of claim 1, wherein the
Prakshep Dravya comprises one or more of flavoring or aromatic agents, texture
forming agents, coloring agents and sweetening agents.
6. The process of preparing nutraceutical bar dosage form of claim 5, wherein the
sweetening agent is selected form the group consisting of sugar sweetener and
non-sugar sweetener.
7. The process of preparing nutraceutical bar dosage form of claim 6, wherein
sugar sweeteners is selected form the group consisting of glucose (liquid or
solid), dextrose, sucrose, fructose, lactose, maltose, glycerine, brown sugar,
galactose, invert syrup and corn syrup.

8. The process of preparing nutraceutical bar dosage form of claim 6, wherein the non-sugar sweetener is selected from the group consisting of brazzein, curculin, miraculin, monellin, pentadin, thaumatin, fructose, glycyrrhizin, hydrogenated starch hydrolysates, fructo-oligo-saccharides (fructans, oligosaccharides, oligofructose and inulin), lactitol, mabinlin, maltitol, mannitol, inositol, erythritol, xylitol, sorbitol, stevia, tagatose, saccharin, cyclamate, alitame, aspartame, sucralose, neotame and acesulfame potassium and its sodium and calcium salts, aspartame-acesulfame salt, neohesperidine dihydrochalcone, and isomalt.
9 A sugar free nutraceutical bar dosage form, wherein the dosage form comprises Pradhana Dravya, Samsadhana Dravya, Prakshep Dravya, Yamaka Dravya and syrup ingredients, wherein the Prakshep Dravya comprises one or more non-sugar sweeteners.
10. The nutraceutical bar dosage form of any of the preceding claims, and process of preparation thereof, as described and illustrated in the examples herein.