ORGN
IN/PCT/2002/01707/MUM
FORM2
THE PATENTS ACT, 1970
(39 of 1970)
&
The Patents Rules, 2003
COMPLETE SPECIFICATION
(See section 10; rule 13)
1. Title of the invention. - ORAL COMPOSITION COMPRISING CHALK AND
SELECTIVE PARTICULATE MATERIAL

2. Applicant(s)
(a) NAME:
(b) NATIONALITY:
(c) ADDRESS:

HINDUSTAN LEVER LIMITED
a company incorporated under the Indian Companies Act, 1913 and having its registered office at
Hindustan Lever House, 165/166, Backbay Reclamation, Mumbai - 400 020, Maharashtra, India

3. PREAMBLE TO THE DESCRIPTION
The following specification particularly describes the invention and the manner in which it is to be performed:
GRANTED

14-11-2005

The present invention relates to a composition according to the preamble of claim l.
The inclusion of abrasives in oral compositions such as toothpaste is well known. The abrasive has a cleaning as well as a polishing/whitening benefit. The removal of tartar from the tooth surface is thought to reduce the incidence of caries.
Of the abrasives typically used in oral care formulations chalk is one of the most preferred since it is inexpensive and provides an acceptable degree of abrasion for use in oral care.
To improve the abrasivity of a toothpaste composition it is known to use calcined alumina, which is a particulate material having a hardness which is significantly higher than chalk. A disadvantage of calcined alumina is that it is reactive with many of the other ingredients used in toothpastes around the world.
The abrasivity of a toothpaste is measured according to a protocol described in the Journal of Dental Research (1976) 55(4), 563. This describes how the Relative Dental Abrasion (RDA) is evaluated. In Advanced Dental Research Vol 11, (4) pp576-579 is described a method for evaluating the Pellicle Cleaning Ratio (PCR) which is commonly used as a measure of cleaning.
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Ideally, a toothpaste will be capable of cleaning the teeth without wearing down the tooth enamel and dentine. So while it is necessary to have a cleaning efficacy a toothpaste with too high an RDA is undesirable.
While the RDA of chalk is generally accepted it would be of great benefit to the consumer if it could be reduced without compromising the cleaning efficacy.
It is also important that the materials used as abrasive do not react with any of the other material commonly used in toothpastes.
We have surprisingly found that the inclusion of certain hard particulate material in a chalk-containing oral composition can in fact reduce the RDA of the composition while actually maintaining or improving the PCR.
Accordingly, the invention provides an oral composition according to claim 1.
The particulate material of the invention has an average particle size preferably ranging from 0.1 to 10 um in diameter, preferably from 1 to 7 um and especially from 1.5 to 3 um.
The particulate material used in the invention is tungsten carbide, which has an average particles size in the region of 1.6 um or silicon carbide, which has an average particles size in the region of 2 um.
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The oral composition according to the invention comprise further ingredients which are common in the art, such as:
antimicrobial agents, e.g. Triclosan, chlorhexidine, copper-, zinc- and stannous salts such as zinc citrate, zinc sulphate, zinc glycinate, sodium zinc citrate and stannous pyrophosphate, sanguinarine extract, metronidazole, quaternary ammonium compounds, such as cetylpyridinium chloride; bis-guanides, such as chlorhexidine digluconate, hexetidine, octenidine, alexidine; and halogenated bisphenolic compounds, such as 2,2' methylenebis-(4-chloro-6-bromophenol) ;
anti-inflammatory agents such as ibuprofen, flurbiprofen, aspirin, indomethacin etc.;
anti-caries agents such as sodium- and stannous fluoride, aminefluorides, sodium monofluorophosphate, sodium trimeta phosphate and casein;
plaque buffers such as urea, calcium lactate, calcium glycerophosphate and strontium polyacrylates;
vitamins such as Vitamins A, C and E;
plant extracts;
desensitising agents, e.g. potassium citrate, potassium chloride, potassium tartrate, potassium bicarbonate, potassium oxalate, potassium nitrate and strontium salts;
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anti-calculus agents, e.g. alkali-metal pyrophosphates, hypophosphite-containing polymers, organic phosphonates and phosphocitrates etc.
biomolecules, e.g. bacteriocins, antibodies, enzymes, etc.;
flavours, e.g. peppermint and spearmint oils;
other proteinaceous materials such as collagen;
preservatives;
opacifying agents;
colouring agents;
pH-adjusting agents;
sweetening agents;
pharmaceutically acceptable carriers, e.g. starch, sucrose, water or water/alcohol systems etc.;
surfactants, such as anionic, nonionic, cationic and zwitterionic or amphoteric surfactants;
particulate abrasive materials.such as silicas, aluminas, calcium carbonates, dicalciumphosphates, calcium pyrophosphates, hydroxyapatites, trimetaphosphates, insoluble hexametaphosphates and so on, including agglomerated particulate abrasive materials, usually in
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amounts between 3 and 60% by weight of the oral care composition.
humectants such as glycerol, sorbitol, propyleneglycol, xylitol, lactitol etc.;
binders and thickeners such as sodium carboxymethyl-cellulose, xanthan gum, gum arable etc. as well as synthetic polymers such as polyacrylates and carboxyvinyl polymers such as Carbopol®;
polymeric compounds which can enhance the delivery of active ingredients such as antimicrobial agents can also be included. Examples of such polymers are copolymers of polyvinylmethylether with maleic anhydride and other similar delivery enhancing polymers, e.g. those described in DE-A-3,942,643 (Colgate);
buffers and salts to buffer the pH and ionic strength of the oral care composition; and
other optional ingredients that may be included are e.g. bleaching agents such as peroxy compounds e.g. potassium peroxydiphosphate, effervescing systems such as sodium bicarbonate/citric acid systems, colour change systems, and so on.
Liposomes may also be used to improve delivery or stability of active ingredients.
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The oral compositions may be in any form common in the art, e.g. toothpaste, gel, mousse, aerosol, gum, lozenge, powder, cream, etc. and may also be formulated into systems for use in dual-compartment type dispensers.
Embodiments according to the present invention will be further illustrated by way of the following example.
EXAMPLE
The following experiment illustrates how the use of a particulate material according to the invention may reduce the RDA of a standard chalk toothpaste while improving the PCR.
The RDA and PCR were measured using the protocols referred to above.
The paste used was a standard paste commonly used in the art. Precipitated calcium carbonate (PCC) was the chalk abrasive used to illustrate the effect of the tungsten carbide (WC).

Abrasives used RDA PCR
PCC 125.61 80.52
PCC+0.25% w/w WC 103.83 84.62
PCC+0.5% w/w WC 87.65 91.95
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WE CLAIM:
1. Oral composition comprising chalk, characterised in that it comprises a particulate material selected from the group consisting of silicon carbide and tungsten carbide and having an average particle size ranging from 1 to 10 urn in diameter.
2. Oral composition as claimed in claim 1, wherein the particulate material has an average particle size ranging from 1 to 7 urn in diameter.
3. Oral composition comprising chalk, said oral composition selected from the group comprising toothpaste, gel, mousse, aerosol, gum, lozenge, Powder and cream characterised in that it comprises a particulate material selected from the group consisting of silicon carbide and tungsten carbide and having an average particle size ranging from 1 to 10 urn in diameter.
Dated this 29th day of November 2002
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