FIELD OF THE INVENTION The present invention relates to certain substituted phenyl oxazolidinones and to the processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococC1, streptococC1 and enterococC1 as well as anaerobic organisms such as BacteR10ides spp. and Clostridia spp. speC1es, and aC1d fast organisms such as Mvcobacterium tuberculosis, Mycobacterium avium and Mvcobacterium spp. BACKGROUND OF THE INVENTION Increasing antibacterial resistance in Gram positive bacteria has presented a formidable treatment problem. The enterococC1, although traditionally non virulent pathogens, have been shown, when assoC1ated with VancomyC1n resistance, to have an attributable mortality of approximately 40%. Staphylococcus aureus, the traditional pathogen of post operative wounds, has been resistant to PeniC1llin due to production of peniC1llinases. This resistance was overcome by the development of vaR10us peniC1llinase stable p lactams. But the pathogen responded by synthesizing a modified target peniC1llin binding protein- 2' leading to less affinity for (3 lactam antibiotics and a phenotype known as MethiC1llin Resistant S. aureus (MRSA). These strains, till recently were susceptible to VancomyC1n, which inspite of its vaR10us drawbacks, has become the drug of choice for MRSA infections. Streptococcus pneumoniae is a major pathogen causing pneumonia, sinusitis and meningitis. Until very recently it was highly susceptible to peniC1llin. Recently though, different PBP 2' strains with different susceptibility to peniC1llin have been reported from across the globe. Oxazolidinones are a new class of synthetic antimicrobial agents which kill gram positive pathogens by inhibiting a very early stage of protein synthesis. Oxazolidinones inhibit the formation of ribosomal initiation complex involving 30S and SOS ribosomes leading to prevention of initiation complex formation. Due to their novel mechanism of action, these compounds are active against pathogens resistant to other clinically useful antibiotics. SUMMARY OF THE INVENTION The invention involves the synthesis; identification and profiling of oxazolidinone molecules which have good activity against multiply resistant gram positive pathogens like MRSA, VRE and PRSP. Some ol' these molecules have activity against MDR-TB and MAI strains, while others have significant activity against important anaerobic bacteria. The present invention provides processes for the syntheses of phenyloxazohdinone derivatives which can exhibit significant antibacterial activity against multiply resistant gram positive pathogens like MRSA. VRE and PRSP against MDR-TB and MAI strains, in order to provide safe and effective treatment of bacterial infections. In accordance with one aspect of the invention, there are provided compounds having the structure of Formula I (FORMULA REMOVED) and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, esters, enantiomers, diastereomers. N-oxides. polymorphs, prodrugs or metabolites, wherein T is a five to seven heterocyclic ring, substituted heterocyclic ring, aryl, substituted aryl, bound to the ring C with a linker W, for example, particular forms of T are selected from aryl and live membered heteroaryl which are further substituted by a group represented by R, wherein R is H, C1-6 alkyl, F, C1, Br, I, -CN, COR5, COOR5, N(R6,R7), NHC0C(R8, R9. R10). CON (R8, R7), CH2NO2, NO2, R8, CHR9, -CH=N- OR10, -C=CH-R5, OR5, SR5. -C(RQ)=C(R9)N02, alkyl substituted with one or more of F, Cl, Br, I, OR4, SR4 wherein R4 is hydrogen, alkyl, C1-12 cycloalkyl, C, , alkoxy, aryl, heteroaryl, alkoxycarbonyl or alkyl substituted with one or more of F, Cl, Br, I or OH; R5 is , alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl substituted with one or more of F, Cl, Br, I or OH, aryl or heteroaryl; R6 and R7 are independently H, optionally substituted alkyl, C3-12 cycloalkyl, C1-6 alkoxy; and R9 are independently H, alkyl, F, Cl, Br, I, alkyl substituted with one or more of F, Cl, Br and I, OR5. SR.,. R10= H, optionally substituted C|.,2 alkyl, C3-12 cycloalkyl, C1-6 alkoxy. alkyl. aryl or heteroaryl; n is an integer in the range from 0 to 3; X is CH, CH-S, CH-O, N or CHNR11, wherein R11 is hydrogen, optionally substituted alkyl, C3- 12 cycloalk alkoxy, C1-6 alkyl, C1.alkylcarbonyl, C1-6 alkylcarboxy, aryl or heteroaryl; E is hydrogen, hydroxy or lower alkyl (C1-C4); Y and Z are independently hydrogen, C1-6 alkyl, cycloalkyl or a C bridging group; U and V are independenth hydrogen, optionally substituted C alkyl, F, C1, Br, I, C alkyl substituted with one or more of F, C1, Br, I; W is (CH2)o.n, CO. CH.NH, -NHCH2, -CH2NHCH2, -CH2N (R10CH2-, CH2NCR, CH(R,,), S, CH2CCO), NH. O, NR,,, (C0)CH2, N(R11)CON(R,,), N(R11)C(=S)N(Ri,), SO2, SO, wherein n' is an integer in the range from 0 to 3; R,, is hydrogen, optionally substituted C1-12 ^Ikyl, C. |-, cycloalkyl, C,_g alkoxy, C1-6 alkyl, C1.ealkylcarbonyl, C1-6 alkylcarboxy, aryl or heteroaryl; and R, is -NHC(=0)R2. N(R3.R4), OR3, -NR2C(=S)R3, -NR2C(=S)SR3, wherein R2 is hydrogen, C alkyl, C, cycloalkyl, Cj ^ alkoxy, C| ^ alkyl substituted with one or more of F, C1, Br, I, OH; R3. R4 are independently hydrogen, Cj j^ alkyl, C3-12 cycloalkyl, C alkoxy, aiy 1. heteroaryl, C 1.6 alkoxycarbonyl or Cj ^ alkyl substituted with one or more of F, C1. Br. 1 or OH. Particular compounds of Formula I have Ri as acetamide, halogen, ether linked heteroaryl or amino-heteroaryl, substituted acetamide and the most preferred compounds in this series would be prepared as the optically pure enantiomers having the (S)-configuration according to the Cahn-Ingold-Prelog notation at C5 of the oxazolidinone ring. Other particular compounds of Formula I containing D ring as furanyl, thienyl, and pyrrolyl ring systems and further substituted by substitutions G, J and L are represented by (FORMULA REMOVED) and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, esters, enantiomers, diastereomers, N-oxides. polymorphs, prodrugs or metabolites, wherein R, is-NHC(=0)R2, -N(R3. R4). -NR2C(=S)R3,-NR2C(=S)SR3 or-OR3, wherein R2, R3, R4 are independently hydrogen. C, ,, alkyl, C3 1, cycloalkyl, C1-6 alkoxy, aryl, heteroaryl, C1-6 alkoxycarbonyl or C1-6 alkyl subslilulcd with one or more of F, C1, Br, I or OH; for example, can be of the formula -NH(C=0)R2 wherein R2 is CH3, CH2F, CHF2, CF3, CH2C1, CHC12, CC13; and R3, R4 can be heteroaryl rings such as isoxazolyl, thiazolyl, or pyridyl; U and V are independently hydrogen, optionally substituted C1-6 alkyl, F, C1, Br, C1-12 alkyl substituted with one or more of F, C1. Br. I; Y and Z are independently hydrogen. C1-6 alkyl, C3-12 cycloalkyl, C0.3 bridging group; X is CH, CH-S, CH-0, N or CHNR11, wherein R11 is hydrogen, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C|-6 alkoxy, C1.(, alkyl carbonyl, C1-6 alkylcarboxy, aryl or heteroaryl; E is hydrogen, hydroxy or lower alkyl (C1-C4); W is (CH2)o.n, C=0, CH2NH. NHCH2, CH2NHCH2, CH2N(Ri,)CH2, CH2N(R11), CH(Ri,), S, CH2(C=0), NH, O, (C)CH2. N(R,|)C0N(R,,), SO2, SO, NR,,, N(R11)C(=S)N(R11), wherein n' is an integer in the range from 0 to 3; R11 is hydrogen, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, alkoxy, C1-6 alkyl carbonyl, C1-6 alkylcarboxy, aryl or heteroaryl; Qi is O, S or NR11, wherein R is as defined above; G, J, L are independently H. C,.,, alkyl. F. C1, Br, I, -CN, COR5,COOR5, N(R6,R7), NHCOCCR8, R9, R10). CON (R6. R7). CH2NO2, NO2, CH2R8, CHR9, -CH = N-OR10, -C-CH-R5, OR5, SR5, -C(R9)=C(R9)N02. CM2 alkyl substituted with one or more of F, C1, Br and I, OR4, SR4, wherein R4 is as defined above; Rs is H, C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl substituted with one or more of F. C1, Br, I or OH, aryl or heteroaryl; R6 and R7 are independently H, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy; Rg and R9 are independently H, C1-6 alkyl, F, C1. Br. I. C1-12 alkyl substituted with one or more of F, C1, Br, I, OR5, SR4, N(R6,R7); R10= H. optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl, aryl or heteroaryl; and n is an integer in the range from 0 to 3. In some compounds represented by Formula II, ring C may be 6-8 membered in size and the ring may have either two or three caition atoms between each nitrogen atom, for example: (FORMULA REMOVED) The ring C may be bridged to form a bicyclic system as shown below: (FORMULA REMOVED) When ring C is optional 1} substituted at positions Y and Z, particular examples with alkyl groups, cycloalkyl groups, nuoro group, carboxylic and corresponding esters, amides, substituted alkyls or bridging alk> 1 groups are as shown below: In addition to the above, ring C also includes the following structures: Wherein n is as defined earlier.In accordance with a third aspect of the present invention, there are provided compounds represented by Formula III (FORMULA REMOVED) wherein R, is -NHC(=0)R2, -N(R3,R4). -NR2C(=S)R3, -NR2C(=S)SR3 or -OR3 wherein R2, R3, R4 are independently hydrogen, C, |, alk> 1. C\ ,, cycloalkyl, C1-6 alkoxy, aryl, heteroaryl, C1-6 alkoxycarbonyl or C1-6 alkyl substituted with one or more of F, C1, Br, I or OH; for example, Rj can be of the formula -NH(C=0)R2 wherein Rj is CH3, CHjF, CHF2, CF3, CH2C1, CHC12, CC13; and R3, R4 can be heteroaryl rings such as isoxazolyl, thiazolyl, or pyridyl; U and V are independently hydrogen, optionally substituted C1-6 alkyl, F, C1, Br, C1-12 alkyl substituted with one or more of F. C'l, Br, 1; Y and Z are independently hydrogen, C1.^ alkyl, C3-12 cycloalkyl, or a C0-3 bridging group; X is CH, CH-S, CH-0, N or CHNR11. wherein R11 is hydrogen, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl carbonyl. Cue alkylcarboxy, aryl or heteroaryl; E is hydrogen, hydroxy or lower alkyl (C1-C4); W is (CH2)o.n', C=0, CH2NH, NI-ICH2. CH2NHCH2, CH2N(Ri,)CH2, CH2N(R11), CH(R,,), S, CH2(C=0), NH, O, (C0)CH2. N(R|,)C0N(R11), SO2, SO, NR,,, N(R,,)C(=S)N(Ri,); wherein n' is an integer in the range from 0 to 3: R,, is hydrogen, optionally substituted C1.,2 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl carbonyl, C\.e alkylcarboxy, aryl or heteroaryl; G, J, L are independently H. C1.f, alkyl, F, C1, Br, I, -CN, COR5,COOR5, N(R6,R7), NHC0C(R8, R9, R,o), C0N(R6, R7). CH2NO2, NO2, CH2R8, CHR9, -CH - N-OR10, -C=CH-R5, OR5, SR5, -C(R9)=C(R9)N02, C1-12 alkyl substituted with one or more of F, C1, Br, I, OR4, SR4, wherein R4 is the same as above; R, is H, C1-12 alkyl, C3.,2 cycloalkyl, C1-6 alkoxy, C1-6 alkyl substituted with one or more F. C1. Br. I or OH, aryl or heteroaryl; Re and R7 are independently H, optionally substituted C,.i2 alkyl. C;,.,2 cycloalkyl, C1-6 alkoxy; Rg and R9 are independently selected from H, C1-6 alkyl, F, C1, Br. 1, C|.,2 alkyl substituted with one or more of F, C1, Br, I, OR5, SR4, N(R6,R7); R10= H, optionally substituted C,.,2 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl, aryl or heteroaryl; and n is an integer in the range from 0 lo 3. Particular G, J and L subsliiuiions can include nitro, aldehydes and halides. Other particular compounds of Formula III are as follows: Compound No 2: (S)-N-[[3-[3-Fluoro-4-[N-l-{2-thienyl (5-nitro) methyl)} 1,2,5,6- tetrahydropyrid-4-\l]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide. Compound No 3: (S)-N-[[3-[3-Muoro-4-[N-l-{2-thienoyl(5-nitro)}-l,2,5,6-tetrahydropyrid-4-yl]phenyl]-2-o.\o-5-oxazolidinyl]methyl] acetamide. In accordance with a foiuih aspect of the present invention, there are provided compounds represented by FoR11uiki IV (FORMULA REMOVED) R, is -NHC(=0)R2, -N(R3, R4), -NR2C(=S)R3,-NR2C(=S)SR3, -OR3 wherein R2, R3, R4 are independently hydrogen, C^ ,, alkyl. C. ,2 cycloalkyl, C1-6 alkoxy, aryl, heteroaryl, C1-6 alkoxycarbonyl or C1-6 alkyl suhsiiiuted with one or more of F, C1, Br, I or OH; for example, Ri can be of the formula -NH(C=0)R2 wherein R2 is CH3, CH2F, CHF2, CF3, CH2C1, CHC12, CC13; and R3, R4 can be heteroaryl rings such as isoxazolyl, thiazolyl, or pyridyl; U and V are independently hydrogen, optionally substituted C1-6 alkyl, F, C1, Br, C1-12 alkyl substituted with one or more of F. C1, Br, I; Y and Z are independently hydrogen. C1-6 alkyl, C3-12 cycloalkyl, C0.3 bridging group; X is CH, CH-S, CH-0, N or C1 INR,,. wherein R11 is hydrogen, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkox\. C1-6 alkyl carbonyl, C1-6 alkylcarboxy, aryl or heteroaryl; E is hydrogen, hydroxy or lower alkyl (C1-C4); W is (CH2o-ns C=0, CH2NH. NHCH2, CH2NHCH2,CH2N(R,,)CH2,CH2N(Ri,),CH(R,i), S, CH2(C=0), NH, O, (C0)CH2. N(R,i)C0N(R,i), SO2, SO, NR11, N(R11)C(=S)N(R11), wherein n' is an integer in the range from 0 to 3: R11 is hydrogen, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alk\ I carbonyl. C1-6 alkylcarboxy, aryl or heteroaryl; Qi is O, S or NR11, wherein R| 1 is as defined earlier; G, J, L are independently H. C,., alkyl. F, C1, Br, I, -CN, COR5, COOR5, N(R6,R7), NHC0C(R8, R9, R10), CON (Rc-Ry). CH2NO2, NO2, CH2R8, CHR9, -CH=N-OR,o, -C=CH-R5, OR5, SR5, -C(R9)=C(R9)N02. CM2 alkyl substituted with one or more of F, C1, Br, I, OR4, SR4, wherein R4 is as above; R5 is H. CM: alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl substituted with one or more of F, C1, Br. 1 or OH. aryl or heteroaryl; R6 and R7 are independently H, optionally substituted C1-12 alk> 1. C3-12 cycloalkyl, C1-6 alkoxy; Rg and R9 are independently H, C1=6 alkyl, F, C1, Br, I, C1-12 alk\ 1 substituted with one or more of F, C1, Br and I, OR5, SR4, N(R6,R7); R10= H, optionally substituted CM2 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl, aryl or heteroaryl; and n is an integer in the range from 0 to 3. Particular G, J and L subsiiiulions are nitro, aldehydes and halides. A particular compound of Formula IV is Compound No. 5: 5(S)-Iso.\azol-3-\ l-aminomethyl-3-[3-Fluoro-4-[N-l-(5-nitro-2-furyl)methyl]l,2,5,6-tetrahydrop\rid-4->l]phenyl]oxazolidin-2-one. Compounds of the preseni in\ention can be useful antimicrobial agents, effective against a number of human and veterinar\ pathogens, particularly aerobic Gram-positive bacteria, including multiply-antibiotic resistant staphylococC1 and streptococC1 as well as anaerobic organisms such as Mycobacterium uiberculosis and other mycobacterium speC1es. For preparing pharmaceutical compositions from the compounds described by this invention, inert, pharmaceutically acceptable carriers can be either solid or liquid. Solid form preparations include powders, tablets, dispersible granules, capsules, cachets, suppositories and ointments. A solid carrier can be one or more substances which may also act as diluents, flavouring agents, solubilizers, lubricants, suspending agents, binders or tablets disintegrating agents; it can also be as finely divided solid which is in admixture with the finely divided active compound. For the preparation of tablets, the active compound is mixed with carrier having the necessary binding properties in suitable proportions and compacted in the shape and size desired. The powders and tablets preferably contain from about 5 to about 70 percent of the active ingredient. Suitable solid carriers are lactose, pectin, dextrin, starch, gelatin, tragacanth, low melting wax, cocoa butter, and the like. The term "preparation" is intended to include the formulation of the active compound with encapsulating material as carrier providing a capsule in which the active component (with or without other carriers) is surrounded by carrier, which is thus in assoC1ation with it. Similarly, capsules can be used as solid dosage forms suitable for oral administration. Liquid form preparations include solutions, suspensions and emulsions. As an example may be mentioned water or water-propylene glycol solutions for parenteral injection. Such solutions are prepared so as to be acceptable to biological systems (isotoniC1ty, pH, etc.). Liquid preparations can also be formulated in solution in aqueous polyethylene glycol solution. Aqueous solutions suitable for oral use can be prepared by dissolving the active component in water and adding suitable colorants, flavours, stabilizing and thickening agents as desired. Aqueous suspension suitable for oral use can be made by dispersing the finely divided active component in water with viscous material, i.e. natural or synthetic gums, resins, methyl cellulose, sodium carboxymethyl cellulose and other well-known suspending agents. Ointment preparations contain heavy metal salts of a compound of Formula I with a physiologically acceptable carrier. The carrier is desirably a conventional water-dispersible hydrophilic or oil-in-water carrier, particularly a conventional semi-soft or cream-like water-dispersible or water soluble, oil-in-w ater emulsion infected surface with a minimum of discomfort. Suitable compositions may be prepared by merely incorporating or homogeneously admixing finely divided compounds with the hydrophilic carrier or base or ointment. The pharmaceutical preparations can be in unit dosage form. In such forms, the preparation is subdivided into unit doses containing appropriate quantities of the active component. The unit dosage form can be a packaged preparation, the package containing discrete capsules, powders in vials or ampoules, and ointments capsule, cachet, tablet, gel, or cream itself or it can be the appropriate number of any of these packaged forms. The quantity of active compound in a unit dose of preparation may be varied or adjusted from less than 1 mg to several grams according to the particular application and the potency of the active ingredient. In therapeutic use as agents for treating bacterial infections, the compounds utilized in the pharmaceutical method of this invention are administered at the initial dosage of about 3 mg to about 40 mg per kilogram daily. The dosages, however, may be varied depending upon the requirements of the patient and the compound being employed. Determination of the proper dosage for a particular situation is within the smaller dosages which are less than the optimum dose. Small increments until the optimum effect under the daily dosage may be divided and administered in portions during the day if desired. In one aspect, the invention provides process for the syntheses of compounds of Formulae I, II, III and IV. Pharmaceutically acceptable non-toxic aC1d addition salts of the compounds of the present invention of Formulae I, II, III and IV may be formed with inorganic or organic aC1ds, by methods well known in the art. The present invention also includes within its scope prodrugs of the compounds of Formulae I, II, III and IV. In general, such prodrugs will be functional derivatives of these compounds which readily get converted in vivo into defined compounds. Conventional procedures for the selection and preparation of suitable prodrugs are known to the artisan of ordinary skill in the art. The invention also includes pharmaceutically acceptable salts, the enantiomers, diastereomers, N-oxides, metabolites in combination with pharmaceutically acceptable carrier and optionally included exC1pients. Other advantages of the invention will be set forth in the description which follows, and in part will be apparent from the description, or may be leaR11ed by the practice of the invention. DETAILED DESCRIPTION OF THE INVENTION The compounds of the present invention may be prepared by following the reaction sequences as depicted in the schemes defined below. (FORMULA REMOVED) In scheme I, the amine of Formula V wherein Mi is NH, NHR13, -CH2NHR13, wherein Ri3 is H, ethyl, methyl, isopropyl, acetyl, cyclopropyl, alkoxy; Ri is -NHC(=0)R2, -N(R3, R4), -NR2C(=S)R3, -NR2C(=S)SR3 or -OR3. wherein R2, R3, R4 are independently hydrogen, C, i^ alkyl, C1-6^ cycloalkyl, C1-6 alkoxy, aryl, heteroaryl, C1-6 alkoxycarbonyl or C1-6 alkyl substituted with one or more of F, C1, Br, I or OH; for example, Ri can be of the formula -NH(C=0)R2 wherein R2 is CH3, CH2F, CHF2, CF3, CH2C1, CHC12, CC13; and R3, R4 can be heteroaryl rings such as isoxazolyl, thiazolyl,or pyridyl; E is hydrogen, hydroxy or lower alkyl (C1-C4); Y and Z are independently hydrogen, Cj j, alkyl, C, .^ cycloalkyl or C„ bridging groups; U and V are independently hydrogen, optionally substituted Cj ^ alkyl, F, C1, Br, I, Cj ^^ alkyl substituted with one or more of F, C1. Br, I, is reacted with a heteroaromatic compound of Formula R-T-W-R12 wherein T is a five to seven membered heterocyclic ring, substituted heterocyclic ring, aryl, substituted aryl, bound to the ring C with a linker W. for example, particular forms of T are selected from aryl and five membered heteroaryl which are further substituted by a group represented by R, wherein R is H, C1-6 alkyl, F, C1. Br, 1. -CN, COR5, COOR5, N(R6,R7), NHC0C(R8, R9, R10), CON (R11, R7), CH2NO2, NO2, CH2R8, CHR9, -CH=N-OR10, -C=CH-R5, OR5, SR5, - C(R9)=C(R9)N02, C1-12 alkyl substituted with one or more F, C1, Br, I, OR4, SR4, wherein R4 is hydrogen, C,,^ alkyl, C^ ,2 cycloalkyl, C1-6 alkoxy, aryl, heteroaryl, C 1.6alkoxycarbonyl or C1-6 alkyl substituted with one or more of F, C1, Br. 1 or OH; R5 is H, C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl substituted with one or more of F, C1, Br, I or OH, aryl or heteroaryl; Re and R7 are independently selected from H, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1. 6 alkoxy; Rg and R9 are independently H, C1-6 alkyl, F, C1, Br, I, C1-12 alkyl substituted with one or more of F, C1, Br and I, OR5, SR4. N(R6,R7); R10= H, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl, aryl or heteroaryl; W is (CH2)o.n-, C=0, CH2NH, NHCH2, CH2NHCH2, CH2N(R11)CH2, CHzNCR11), CH(R11), S, CH2(C=0),NH, O, (C0)CH2. N(Ri,)CON(R11), SO2, SO, NR|,,N(R,,)C(=S)N(R,,), whereinn' is an integer in the range from 0 to 3; R| 1 is hydrogen, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl carbonyl, C1-6 alkylcarboxy, aryl or heteroaryl; and R12 is a suitable leaving group well known to one of ordinary skill in the art such as fluoro, chloro, bromo, SCH3, -SO2CH3. -SO2CF3, Tos, OCeHj, -COOH or-CHO-. For the preparation of compounds of Formula I when W is equal to CH2, the corresponding aldehyde can be used through a process of reductive amination and is attached to the amine of Formula V. Similarly, for the preparation of compound of Formula I wherein W is equal to C = O, the corresponding aC1d can be used and the amine of Formula V can be acylated through activated esters in the presence of condensing agents, for example, 1,3-dicyclohexylcarbodiimide (DCC) and l-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC). Other methods of acylation can also be employed. The preparation of the compound of Formula II can be accomplished as exemplified below by two methods A and B as shown in Scheme II: (SCHEME REMOVED) The amine of Formula V wherein Mi is NH, NHR13, -CH2NHR13, wherein R13 is H, ethyl, methyl, isopropyl, acetyl, cyclopropyl, alkoxy; R, is -NHC(=0)R2, -N(R3, R4). -NR2C(=S)R3, -NR2C(=S)SR3 or -OR3, wherein R2, R3, R4 are independently hydrogen, C| 1, alkyl, C, ,2 cycloalkyl, C1-6 alkoxy, aryl, heteroaryl, C1-6 alkoxycarbonyl or Cj ^ alkyl substituted with one or more of F, C1, Br, I or OH; for example, Ri can be of the formula -NH(C=0)R2 wherein R2 is CH3, CH2F, CHF2, CF3, CH2C1, CHC12, CC13; and R3, R4 can be heteroaryl rings such as isoxazolyl, thiazolyl, or pyridyl; E is hydrogen, hydroxy or lower alkyl (C1-C4); Y and Z are independently hydrogen. Cj^ alkyl, C^ ,2 cycloalkyl or C^ 3 bridging groups; U and V are independently hydrogen, optionally substituted C1-6 alkyl, F, C1, Br, I, C, ,2 ^Ikyl substituted with one or more of F, C1. Br, I, is reacted with a heteroaromatic compound of Formula VI wherein R12 is a suitable leaving group such as tluoro, chloro, bromo, SCH3, -SO2CH3, -SO2CF3, Tos, OCeHs, -COOH or -CHO-, other suitable leaving groups are well known to one of ordinary skill in the art; Q] is O, S oR11Rii, wherein R11 is hydrogen, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl carbonyl. C1-6 alkylcarboxy, aryl or heteroaryl; G, J, L are independently H, C1-6 alkyl, F, C1, Br, I, -CN, COR5,COOR5, N(R6,R7), NHC0C(R8, R9, R10), CON (R11. R7). CH2NO2, NO2, CH2R8, CHR9, -CH - N-OR10, -C^CH-Rj, OR5, SR5, -C(R9)=C(R9)N02, C1-i: alkyl substituted with one or more of F, C1, Br and I, OR4, SR4, wherein R4 is as defined above; R? is H, C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl substituted with one or more of F. C1. Br. I or OH, aryl or heteroaryl; R6 and R7 are independently H, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy; Rg and R9 are independently H, C1-6 alkyl, F, C1. Br. 1, C1-12 alkyl substituted with one or more of F, C1, Br, I, OR5, SR4, N(R6,R7); R10= H, optionally substituted C1-12 alkyl, C3-12 cycloalkyl, C1-6 alkoxy, C1-6 alkyl, aryl or heteroaryl; and n is an integer in the range from 0 lo 3. The reaction can be carried out in a suitable solvent, for example, dimethylformamide, dimethylacetamide, ethanol or ethylene glycol at a suitable temperature in the range of about -70°C to about 180°C to afford compounds of Formula IL The presence of a suitable base such as triethylamine, diisopropylamine, potassium carbonate, sodium bicarbonate is useful in some cases to improve the yield of the reaction. The reductive alkylation oltlie amine intermediate of Formula V with the corresponding heterocyclic aldehydes of the Formula VI, such as furaldehyde (Qi = O, R12 is CHO) using reduC1ng agents well knov\n to one of ordinary skill in the art such as sodium triacetoxyborohydride or sodium cyanoborohydride gives the products of Formula II, wherein W=CH2 as shown in the Scheme II. Method B: The acylation of intermediate amines of Formula V with a heterocyclic aC1d of Formula VI, such as 2- furoic aC1d (Qi = O; Q2 = C; G. J, L = H; R12 =COOH) gives products of Formula II, wherein W=CO, as shown in the Scheme II wherein U, V, Y, Z, X, W, Ql, G, J, L, R12 and E are as defined earlier. AlteR11atively, the compounds having carbonyl link can also be made by reacting heteroaromafic compound of the Formula VI, such as N-methyl pyrrole with the intermediate amine of Formula V, in the presence of triphosgene or phosgene. The carbonyl linkers may also be introduced between heteroaromatic compound, such as 3- bromothiophene and the amine of Formula V with carbon monoxide in the presence of a catalyst, such as Pd (PPh3)2Cl2. The extended chain pyrroles having dicarbonyl linkers can also be obtained from treatment with oxalyl chloride and the amine of ihe Formula V. The reduction of the carbonyl linkers using the standard reduC1ng agents results in the formation of methylene linkers. Mainly amine of Formula V (FORMULA REMOVED) was used for the preparation of compounds of Formula I and Formula II, for example following two speC1fic amines, idenliiled as two different cores, namely (S)-N-[[3-[3-Fluoro-4-[N-l -(1.2,5.6-tetrahydropyrid-4-yl)]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide (Core I) 5(S)-IsoxazoI-3-yl-amino-(N-t-butoxycarbonyl)-N-methyl-3-[3-Fluoro-4-[4-( 1,2,5,6-tetrahydropyrid-4-yl)phenyl]oxazolidin-2-one (Core II) were used for the preparation of analogs. The key intermediate amines of Formula V for the analogue preparation were prepared from commerC1ally available reagcnls, wherein Mi is NH, NHR13, -CH2NHR13, wherein R13 is H, ethyl, methyl, isopropyl. acct\i. csclopropyK alkoxy and Ri, U, V, Y, Z and E are as defined earlier. Some amines of Formula V are already known in the literature and are given by reference and if they have been made for the first time or by different procedures or variation of known procedure, they are described in detail in the experimental section. The optically pure amines of Formula V could be obtained either by one of a number of assymetric syntheses or alteR11atively by resolution from a racemic mixture by selective crystallization of a salt prepared, with an appropriate optically active aC1d, such as dibenzoyl tartrate or 10-camphorsulfonic aC1d, followed by treatment with base to afford the optically pure amine. The transformations effected are described in the experimental section. In the above synthetic methods, where speC1fic aC1ds, bases, solvents, catalysts, oxidising agents, reduC1ng agents etc. are mentioned, it is to be understood that the other aC1ds, bases, solvents, catalysts, oxidising agents, reduC1ng agents etc. may be used. Similarly, the reaction temperature and duration of the reaction may be adjusted according to the desired need. Particular compounds which are capable of being produced by the above mentioned schemes include: Compound No. Chemical Name 1. (S)-N-[[3-[3-Fluoro-4-[N-l-!2-furyl(5-nitro)methyl}l,2,5,6-tetrahydropyrid-4-yl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide, 2. (S)-N-[[3-[3-Fluoro- 4-[N-l-[2-thienyl (5-nitro) methyl)} 1,2,5,6-tetrahydropyrid-4-yl]phenyl]-2-oxo-5-oxazolidinyl]mcthyl]acetamide, 3. (S)-N-[[3-[3-Fluoro-4-[N-l-(2-thienoyl(5-nitro)}-l,2,5,6-tetrahydropyrid-4-yl]phenyl]-2-oxo-5-oxazolidinyl]methyl] acctamide, 4. 5(S)-Isoxazol-3-yl-amino-(N-t-buloxycarbonyl)-N-methyl-3-[3-Fluoro-4-[N-l-(5-nitro-2-furyl)methyl] 1,2,5,6-tetrahydiop} rid-4-yl]phenyl]oxazolidin-2-one, 5. 5(S)-Isoxazol-3-yl-aminomethyl-3-[3-Fluoro-4-[N-l-(5-nitro-2-furyl)methyl] 1,2,5,6-tetrahydropyrid-4-yl]phen}l]oxazolidin-2-one. Most of the compounds were characterized using NMR, IR and were purified by chromatography. Crude products were subjected to column chromatographic purification using silica gel (100-200 or 60-120 mesli) as stationary phase. The examples mentioned below demonstrate the general synthetic procedure as well as the speC1fic preparation for the particular compounds. The examples are given to illustrate the details of the invention and should not be constrained to limit the scope of the present invention as defined by the claims. EXAMPLE 1: Analogs of (S)-N-[[3-[3-Fluoro-4-(l.2.5.6-tetrahvdroDvrid-4-vnphenvl1-2-oxo-5-oxazolidinvl]methvl]acetamide (Core 1) (S)-N-[[3-[3-Fluoro-4-(l,2.5,6-tetrahydropyrid-4-yl)phenyl]-2-oxo-5-oxazoIidinyl] methyl]acetamide (core 1) was prepared according to procedures described in PCT patent application WO 97/30995 and U.S. Patent No. 6,051,716. Method A: General Procedure: The reductive alkylation of the amine intermediate of Formula V with the corresponding heterocyclic aldehydes of the Formula VI, using known reduC1ng agents well known to one of ordinary skill in the art such as sodium triacetoxyborohydride or sodium cyanoborohydride gave the products of Formula II wherein W=CH2 The following compounds were made using this method: Compound No.l: (S)-N-[r3-|3-Fluoro-4-[N-l-|2-furvl(5-nitro)methyn 1.2.5,6-tetrahydropvrid-4-vl1phenYl]-2-oxo-5-oxazolidinvl]methvl1acetamide. To a solution of (S)-N-[[3-[3-Fluoro-4-(l,2,5,6-tetrahydropyrid-4-yl)phenyl]-2-oxo-5- oxazoHdinyl]methyl]acetamide h}drochloride (0.14 g, 0.38 mmol) in tetrahydrofuran (10 mL), 5-nitro-2-furaIdehyde ( 0.08Ig, 0.57 mmol) and molecular sieves added and stirred at RT for 30 min. Then, sodium triacetoxyborohvdride (0.32 g, 1.53 mmol) was added and further stirred for 17hrs. The reaction mixture uas lllicred and the filtrate evaporated in vacuo. The residue obtained was dissolved in dichloromclhane and washed with water. The organic layer was dried over anhydrous sodium sulphate and evaporated in vacuo. The residue was purified by column chromatography, eluting with 2% MeOH/dichloromethane. 'HNMR(CDCl3) 5ppm: 7.4 (d. 1H. Ar-H), 7.1-7.3 (3H, Ar-H), 6.4 (d, IH, Ar-H), 6.1 (t, IH, NH), 6.0 (s, IH, double bond II). 4.7 (m, IH. CH), 4.1 (t, H, CH), 3.4-3.8 (m, 5H), 3.4 (m, 2H, CH2), 2.8 (m, 2H, 4.1 (t, H, C1l). 3.4-3.8 (m, 5H), 3.4 (m, 2H, CH2), 2.8 (m, 2H, CH2), 2.6 (m, 2H, CH2), 2.0 (s, 3H, CH3). Compound No 2: (S)-N-ri 3-13-Fluoro-4-R11-l-{2-thienvl(5-nitro)methyl)} 1,2.5.6-tetrahvdropvrid-4-vl]phenvl]-2-oxo-5-oxazolidinvl]methvl1acetamide. The title compound was prepared using (S)-N-[[3-[3-Fluoro-4-(l, 2, 5, 6-tetrahydropyrid- 4-yl)pheny]]-2-oxo-5-oxazolidin\l] melhyljacetamide hydrochloride and 5-mtro-2- thiophenecarboxaldehyde according 10 Method A, Compound No. 1. H' NMR (CDC13) §ppm: 6.0-7.8 (m, 5H, Ar-H) 6.0 (m, 2H (NH and double bond H) 4.79 (m, IH, CH), 4.18 (t, 2H, CH2) 3.6-3.H (m. 5H). 3.2 (m, 2H, CH2) 2.7 (m, 2H, CH2), 2.4 (m, 2H CH2), 2.0 (s, 3H, CH3). Method B : General Procedure: For the preparation of compound of Formula I wherein W is equal to C = O, the corresponding aC1d of Formula VI is used and the amine of Formula V is acylated through activated esters in the presence vf condensing agents such as 1,3-dicyclohexyl carbodiimide (DCC) and l-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC), along with 1-hydroxybenzotriazole. Other methods of acylation can also be employed. The following compounds were prepared using this method: Compound No 3: (S)-N-fl3-r3-Fluoro-4-R11-l-!2-thienovl(5-nitro)}-1.2.5.6-tetrahvdro pvrid-4-vl]phenyl]-2-oxo-5-oxazolidinvl1methyl] acetamide. To a solution of (S)-N-[[3-[3-Fluoro-4-( 1,2,5,6-tetrahydropyrid-4-yl)phenyl]-2-oxo-5- oxazolidinyl]methyl]acetamide hydrochloride (0.18 g, 0.49 mmol) in N,N-dimethyl formamide which was cooled to 0°C, N-methylmorpholine (0.16g, 1.57 mmol), and 1-hydroxybenzotriazole (0.065g, 0.49 mmol) were added and stirred for 30 min. Then, l-(3-dimethyl aminopropyl)-3- ethylcarbodiimide hydrochloride (HDC) was added and the reaction mixture was stirred at room temperature for 17hrs. The reaetion mixture was evaporated in vacuo and the residue was taken in dichloromethane. The organic layer was washed with water, dried over anhydrous sodium sulphate and evaporated in vacuo. The crude product was purified by column chromatography, eluting with 2% MeOH/dichloromethane. 'HNMR(CDCl3) 5ppm: 7.8 (d. 1H. Ar-H). 7.4 (d. IH, Ar-H) 7.2 (m, 3H, Ar-H), 6.0 (t, IH, NH), 6.0 (broad, s, IH, double bond 11). 4.7 (m, IH, CH), 3.7-4.5 (m, 8H, CH2), 2.6 (m, 2H, CH2) 2.6 (m,2H, CH2), 2.0(s, 3H, CH3). IR: 1704. 1605 cm'' EXAMPLE 2: Analogs of 5(S)-Isoxazol-3-vl-amino-(N-t-butoxvcarbonvl)-N-methyl-3-[3-Fluoro-4-[4-( l,2,5,6-tetrahvdrop\rid-4-vl)phenvl]oxazoUdin-2-one (Core II) The amine, 5(S)-Isoxa7ol-3-yl-amino-(N-t-butoxycarbonyl)-N-methyl-3-[3-Fluoro-4-[4- (l,2,5,6-tetrahydropyrid-4-yl)phenylloxazolidin-2-one was prepared according to the procedure described in PCT patent application WO 00/21960. Compound No.4: 5(S)-Isoxa7.ol-3-amino-(N-t-butoxvcarbonvl)-N-methvl-3-[3-Fluoro-4-[N-l-(5-nitro-2-furvl)methyl] 1.2.5.6-totrahvdropYrid-4-vl]phenvl] oxazolidin-2-one To a solution of 5(S)-Iso.\a/ol-3-yl-amino-(N-t-butoxycarbonyl)-N-methyl-3-[3-Fluoro-4-[4-(l,2,5,6-tetrahydropyrid-4-\l)phenyl]oxazolidin-2-one hydrochloride (0.43 gm, 0.905 mmole) in tetrahydrofuran (10 ml), was added 5-nitro-furan-2-carboxaldehyde (0.191gm, 1.35 mmole) and molecular seive (0.4 gm) at room temperature. The reaction mixture was stirred for half an hour. It was followed b\ the addition of sodium triacetoxy borohydride (0.575 gm, 2.715 mmole) and further stirred fur 3hrs. The reaction mixture was filtered, washed with ethyl acetate, and the filtrate was concentrated under reduced pressure. The residue was dissolved in ethyl acetate and washed with saturated solution of sodium bicarbonate, followed by washing with brine. The organic layer was dried o\ er anhydrous sodium sulphate and concentrated under reduced pressure. The crude product obtained was purified by column chromatography, eluting with 1% methanol in dichloromethane. Yield = 0.4gm, 'HNMR (CDC13) §ppm: 8.25 (d, 1H), 7.38 (d, IH), 7.21-7.15 (m, 2H), 6.54 (d, 2H), 5.95 (m, IH), 6.07 (m, IH), 4.71 (d, IH). 4,35-4.33 (t, IH), 4.14-4.06 (m, 2H), 3.82-3.78 (m, 2H), 3.27-3.26 (m, 2H), 2.82-2.78 (m, 2H). 2.57 (m, 2H). 1.55 (s, 9H) Compound No. 5: 5(SVIsoxa/.ol-3-vl-uminomethvl-3-[3-Fluoro-4-R11-l-(5-nitro-2-furvl) methyl] l,2,5,6-tetrahvdropvrid-4l]phenvi]oxazolidin-2-one To a solution of 5(S)-lsoxazol-3-y]-amino-(N-t-butoxycarbonyl)-N-methyl-3-[3-Fluoro- 4-[N-l-(5-nitro-2-furyl)methyr| 1,2,5,6-tetrahydropyrid-4-yl]phenyl]oxazoIidin-2-one (0.4 g, 0.69 mmol) in dichloromethane at 0 T. trifluoroacetic aC1d was added and the reaction mixture was stirred at room temperature for 3 hrs. The reaction mixture was evaporated in vacuo. The residue was taken in ethyl acC1aie and neutralized with ammonium hydroxide, and washed with water. The organic layer was dried over anhydrous sodium sulphate and evaporated in vacuo. The crude product was purified b> column chromatography, eluting with 1% MeOH in dichloromethane to yield 0.16 g olthe title product. 'H NMR (CDC13) 5ppm; 8.06