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Peptide Mixture For Enhancing Iron Uptake

Abstract: The present disclosure provides for a a peptide mixture comprising: a) a first peptide having an amino acid sequence as set forth in SEQ ID NO: 1; b) a second peptide having an amino acid sequence as set forth in SEQ ID NO: 2; c) a third peptide having an amino acid sequence as set forth in SEQ ID NO: 3; and d) a fourth peptide having an amino acid sequence as set forth in SEQ ID NO: 4. The present disclosure further provides a composition comprising the peptide mixture as described herein and at least one iron salt. The process for preparing the composition and the peptide mixture has also been disclosed herein.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
04 April 2019
Publication Number
41/2020
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
iprdel@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE, #3, 1st Main, Peenya Industrial Area, Phase -1, Bangalore, Karnataka, India, Pin Code-560 058.

Inventors

1. MIRIYALA, Amarnath
Life Science and Technology Centre, ITC Limited, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, Karnataka, India, Pin Code-560 058.
2. GOPAL, Ganesh
Life Science and Technology Centre, ITC Limited, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore, Karnataka, India, Pin Code-560 058.

Specification

I/We Claim:
1. A peptide mixture comprising:
a) a first peptide having an amino acid sequence as set forth in SEQ ID NO: 1;
b) a second peptide having an amino acid sequence as set forth in SEQ ID NO: 2;
c) a third peptide having an amino acid sequence as set forth in SEQ ID NO: 3; and
d) a fourth peptide having an amino acid sequence as set forth in SEQ ID NO: 4.

2. The peptide mixture as claimed in claim 1, wherein the mixture has a protein concentration in a range of 1-2 mg/ml with respect to the mixture.
3. A composition comprising:
(i) a peptide mixture comprising:
a) a first peptide having an amino acid sequence as set forth in SEQ ID NO: 1;
b) a second peptide having an amino acid sequence as set forth in SEQ ID NO: 2
c) a third peptide having an amino acid sequence as set forth in SEQ ID NO: 3;
d) a fourth peptide having an amino acid sequence as set forth in SEQ ID NO: 4; and
(ii) at least one iron salt.
4. The composition as claimed in claim 3, wherein the peptide mixture has a protein concentration in a range of 1-2 mg/ml with respect to the mixture
5. The composition as claimed in claim 3, wherein the peptide mixture and the at least one iron salt has a weight ratio in a range of 1:5 to 1:0.3.
6. The composition as claimed in claim 3, wherein the at least one iron salt is selected from a group consisting of ferrous sulphate, ferric pyrophosphate, ferrous gluconate, ferrous fumarate, anhydrous ferrous carbonate, carbonyl

iron, ferric ammonium citrate, iron choline citrate, and combinations thereof.
7. The composition as claimed in claim 3, wherein the at least one iron salt is ferrous sulphate.
8. A process for preparing the peptide mixture as claimed in claim 1, said process comprises:

a) obtaining a first peptide having an amino acid sequence as set forth in SEQ ID NO: 1;
b) obtaining a second peptide having an amino acid sequence as set forth in SEQ ID NO: 2;
c) obtaining a third peptide having an amino acid sequence as set forth in SEQ ID NO: 3;
d) obtaining a fourth peptide having an amino acid sequence as set forth in SEQ ID NO: 4; and
e) contacting the first peptide, the second peptide, the third peptide, and the fourth peptide, to obtain the peptide mixture.
9. A process for preparing the composition as claimed in claim 3, said process
comprises:
a) obtaining a first peptide having an amino acid sequence as set forth in SEQ ID NO: 1;
b) obtaining a second peptide having an amino acid sequence as set forth in SEQ ID NO: 2;
c) obtaining a third peptide having an amino acid sequence as set forth in SEQ ID NO: 3;
d) obtaining a fourth peptide having an amino acid sequence as set forth in SEQ ID NO: 4;
e) contacting the first peptide, the second peptide, the third peptide, and the fourth peptide, to obtain the peptide mixture; and
f) contacting the peptide mixture to the at least one iron salt, to obtain the composition.

10. The peptide mixture as claimed in claim 1, said mixture enhances iron absorption by intestinal cells.

Documents

Application Documents

# Name Date
1 201941013686-FORM 18 [20-03-2023(online)].pdf 2023-03-20
1 201941013686-STATEMENT OF UNDERTAKING (FORM 3) [04-04-2019(online)].pdf 2019-04-04
2 201941013686-SEQUENCE LISTING(PDF) [04-04-2019(online)].pdf 2019-04-04
2 Correspondence by Agent _Proof of Right,Power of Attorney_17-06-2019.pdf 2019-06-17
3 201941013686-SEQUENCE LISTING [04-04-2019(online)].txt 2019-04-04
3 201941013686-FORM-26 [13-06-2019(online)].pdf 2019-06-13
4 201941013686-Proof of Right (MANDATORY) [13-06-2019(online)].pdf 2019-06-13
4 201941013686-FORM 1 [04-04-2019(online)].pdf 2019-04-04
5 201941013686-COMPLETE SPECIFICATION [04-04-2019(online)].pdf 2019-04-04
5 201941013686-DRAWINGS [04-04-2019(online)].pdf 2019-04-04
6 201941013686-DECLARATION OF INVENTORSHIP (FORM 5) [04-04-2019(online)].pdf 2019-04-04
7 201941013686-COMPLETE SPECIFICATION [04-04-2019(online)].pdf 2019-04-04
7 201941013686-DRAWINGS [04-04-2019(online)].pdf 2019-04-04
8 201941013686-FORM 1 [04-04-2019(online)].pdf 2019-04-04
8 201941013686-Proof of Right (MANDATORY) [13-06-2019(online)].pdf 2019-06-13
9 201941013686-FORM-26 [13-06-2019(online)].pdf 2019-06-13
9 201941013686-SEQUENCE LISTING [04-04-2019(online)].txt 2019-04-04
10 Correspondence by Agent _Proof of Right,Power of Attorney_17-06-2019.pdf 2019-06-17
10 201941013686-SEQUENCE LISTING(PDF) [04-04-2019(online)].pdf 2019-04-04
11 201941013686-STATEMENT OF UNDERTAKING (FORM 3) [04-04-2019(online)].pdf 2019-04-04
11 201941013686-FORM 18 [20-03-2023(online)].pdf 2023-03-20