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“Peroxisome Proliferator Activated Receptor Modulators”
Abstract: The present invention is directed to compounds of the structural Formula: wherein: R1 is H or -C1-C3 alkyl; R2 is selected from the group consisting of -H, -C1-C4 alkyl, -C1-C3 alkyl-CF3, phenyl, and pyridinyl; and R3 is selected from the group consisting of -H, -C1-C4 alkyl, -C1-C3 alkyl-O-CH3, -CH2-cyclopropyl, -CH2-C=CH2, -CH2CH2-(2-F-phenyl), and phenyl substituted with from 1 to 2 fluorines; provided that when R1 and R2 are each H, then R3 is selected from the group consisting of -C1-C4 alkyl, -C1-C3 alkyl-O-CH3, -CH2-cyclopropyl, -CH2-C=CH2, -CH2CH2-(2-F-phenyl), and phenyl substituted with from 1 to 2 fluorines; or stereoisomers and pharmaceutically acceptable salts thereof.
Notices, Deadlines & Correspondence
Patent Information
Applicants
ELI LILLY AND COMPANY
Inventors
1. LANCE ALLEN PFEIFER
2. TIANWEI MA
3. NATHAN BRYAN MANTLO
4. LAURA FREY MICHAEL
5. FESE MAMBO MOKUBE
6. CHAHRZAD MONTROSE-RAFIZADEH
Specification
PLEASE SEE THE SPECIFICATION ATTACHED.
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 2499-KOLNP-2009-(14-07-2009)-FORM-18.pdf | 2009-07-14 |
| 1 | 2499-KOLNP-2009-AbandonedLetter.pdf | 2017-07-11 |
| 2 | 2499-KOLNP-2009-FER.pdf | 2016-07-25 |
| 2 | Form-5.pdf | 2011-10-07 |
| 3 | Form-1.pdf | 2011-10-07 |
| 3 | Form-3.pdf | 2011-10-07 |
| 4 | Form-1.pdf | 2011-10-07 |
| 4 | Form-3.pdf | 2011-10-07 |
| 5 | 2499-KOLNP-2009-FER.pdf | 2016-07-25 |
| 5 | Form-5.pdf | 2011-10-07 |
| 6 | 2499-KOLNP-2009-(14-07-2009)-FORM-18.pdf | 2009-07-14 |
| 6 | 2499-KOLNP-2009-AbandonedLetter.pdf | 2017-07-11 |