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Pharmaceutical Composition Comprising A Quinazoline Compound

Abstract: The present invention has an object to provide a pharmaceutical composition for treating a cancer of colorectal cancer and/or lung cancer. The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating a cancer, and have found that a quinazoline compound has an excellent degradation- inducing action on a G12D mutant KRAS protein and a G12D mutant KRAS inhibition activity and that a pharmaceutical composition containing the compound as an active ingredient can be used as a therapeutic agent for a cancer, completing the present invention. The pharmaceutical composition of the present invention which contains a quinazoline compound or a salt thereof as an active ingredient can be used as a therapeutic agent for a cancer of colorectal cancer and/or lung cancer.

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Patent Information

Application #
Filing Date
18 July 2024
Publication Number
31/2024
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

ASTELLAS PHARMA INC.
5-1, Nihonbashi-Honcho 2-chome Chuo-ku Tokyo 1038411

Inventors

1. NAGASHIMA, Takeyuki
c/o Astellas Pharma Inc. 5-1, Nihonbashi-Honcho 2-chome Chuo-ku Tokyo 1038411

Specification

Documents

Application Documents

# Name Date
1 202447054925-STATEMENT OF UNDERTAKING (FORM 3) [18-07-2024(online)].pdf 2024-07-18
2 202447054925-REQUEST FOR EXAMINATION (FORM-18) [18-07-2024(online)].pdf 2024-07-18
3 202447054925-PROOF OF RIGHT [18-07-2024(online)].pdf 2024-07-18
4 202447054925-PRIORITY DOCUMENTS [18-07-2024(online)].pdf 2024-07-18
5 202447054925-FORM 18 [18-07-2024(online)].pdf 2024-07-18
6 202447054925-FORM 1 [18-07-2024(online)].pdf 2024-07-18
7 202447054925-DECLARATION OF INVENTORSHIP (FORM 5) [18-07-2024(online)].pdf 2024-07-18
8 202447054925-COMPLETE SPECIFICATION [18-07-2024(online)].pdf 2024-07-18
9 202447054925-FORM-26 [22-07-2024(online)].pdf 2024-07-22
10 202447054925-FORM 3 [07-01-2025(online)].pdf 2025-01-07