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Pharmaceutical Composition Having Pyrimidine Compound As Active Ingredient
Abstract: [Problem] To provide a pharmaceutical composition for treating FGFR4 related cancer FGF19 related cancer or FGF19 gene amplification positive liver cancer. [Solution] The inventors perfected the present invention through study of compounds having FGFR4 inhibitory effect verifying that specific pyrimidine compounds have FGFR4 inhibitory effect and that pharmaceutical compositions having these compounds as active ingredients have therapeutic effect against FGFR4 related cancer or in another mode against FGF19 related cancer or in yet another mode against FGF19 gene amplification positive liver cancer.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
26 February 2016
Publication Number
27/2016
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Applicants
ASTELLAS PHARMA INC.
5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
Inventors
1. FUTAMI Takashi
c/o Astellas Pharma Inc. 5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
2. TAKESHITA Rumi
c/o Astellas Pharma Inc. 5 1 Nihonbashi Honcho 2 chome Chuo ku Tokyo
1038411
Specification
SOFT COPY ATTACHED IN PDF
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 201647006685-Correspondence-F1-240816.pdf | 2016-09-21 |
| 1 | Power of Attorney [26-02-2016(online)].pdf | 2016-02-26 |
| 2 | 201647006685-Form 1-240816.pdf | 2016-09-21 |
| 2 | Form 5 [26-02-2016(online)].pdf | 2016-02-26 |
| 3 | Form 3 [23-08-2016(online)].pdf | 2016-08-23 |
| 3 | Form 3 [26-02-2016(online)].pdf | 2016-02-26 |
| 4 | Form 1 [26-02-2016(online)].pdf | 2016-02-26 |
| 4 | Other Patent Document [23-08-2016(online)].pdf | 2016-08-23 |
| 5 | Description(Complete) [26-02-2016(online)].pdf | 2016-02-26 |
| 5 | 201647006685.pdf | 2016-06-08 |
| 6 | 201647006685.pdf | 2016-06-08 |
| 6 | Description(Complete) [26-02-2016(online)].pdf | 2016-02-26 |
| 7 | Form 1 [26-02-2016(online)].pdf | 2016-02-26 |
| 7 | Other Patent Document [23-08-2016(online)].pdf | 2016-08-23 |
| 8 | Form 3 [23-08-2016(online)].pdf | 2016-08-23 |
| 8 | Form 3 [26-02-2016(online)].pdf | 2016-02-26 |
| 9 | 201647006685-Form 1-240816.pdf | 2016-09-21 |
| 9 | Form 5 [26-02-2016(online)].pdf | 2016-02-26 |
| 10 | Power of Attorney [26-02-2016(online)].pdf | 2016-02-26 |
| 10 | 201647006685-Correspondence-F1-240816.pdf | 2016-09-21 |