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Polyethylene Glycol Linked Glp 1 Compounds
Abstract: The invention provides GLP-1 compounds coupled to al leasl one polyethylene glycol molecule.or derivative thereof, resulting in a biologically active peplide with an extended haif-life and a slower clearance when compared to that of unPEGylaied peplidc. These PEGyJated OLP-1 compounds and compositions are useful in treating diabetes, obesity, irritable bowel syndrome and other conditions that would be benefited by lowering pjasma glucose, inhibiting gastric and/or intestinal motility and inhibiting gastric anoVor infesimal emptying, or inhibiting food intake.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
11 August 2005
Publication Number
28/2007
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
Parent Application
Applicants
ELI LILLY AND COMPANY
LILLY CORPORATE CENTER, INDIANAPOLIS, IN 46285, U.S.A.
Inventors
1. RICHARD DENNIS DIMARCHI
10890 WILMINGTON DRIVE CARMEL, INDIANA 46033, U.S.A.
2. WOLFGANG GLAESNER
7512 FIELDSTONE COURT INDIANAPOLIS, INDIANA 46254, GERMANY
3. ROHN LEE MILLICAN, JR.
8145 GRASSY MAEDOW COURT INDIANAPOLIS, INDIANA 46259, U.S.A.
4. ANDREW MARK VICK
10736 GATEWAY DRIVE FISHERS, INDIANA 46038, U.S.A.
5. LIANSHAN ZHANG
13244 SNOW OWL DRIVE CARMEL, INDIANA 46033, U.S.A.
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 01611-kolnp-2005-abstract.pdf | 2011-10-07 |
| 1 | 01611-kolnp-2005-international publication.pdf | 2011-10-07 |
| 2 | 01611-kolnp-2005-claims.pdf | 2011-10-07 |
| 2 | 01611-kolnp-2005-form 5.pdf | 2011-10-07 |
| 3 | 01611-kolnp-2005-description complete.pdf | 2011-10-07 |
| 3 | 01611-kolnp-2005-form 3.pdf | 2011-10-07 |
| 4 | 01611-kolnp-2005-form 1.pdf | 2011-10-07 |
| 4 | 01611-kolnp-2005-form 2.pdf | 2011-10-07 |
| 5 | 01611-kolnp-2005-form 1.pdf | 2011-10-07 |
| 5 | 01611-kolnp-2005-form 2.pdf | 2011-10-07 |
| 6 | 01611-kolnp-2005-description complete.pdf | 2011-10-07 |
| 6 | 01611-kolnp-2005-form 3.pdf | 2011-10-07 |
| 7 | 01611-kolnp-2005-claims.pdf | 2011-10-07 |
| 7 | 01611-kolnp-2005-form 5.pdf | 2011-10-07 |
| 8 | 01611-kolnp-2005-abstract.pdf | 2011-10-07 |
| 8 | 01611-kolnp-2005-international publication.pdf | 2011-10-07 |