DESC:This patent application claims priority benefit of Provisional Patent Application No: 202041019798, entitled “PORTABLE RESPIRATORY SUPPORT DEVICE TO TITRATE OXYGEN CONTENT FOR REDUCING INAPPROPRIATE USE OF OXYGEN”, filed on 11-May-2020. The entire contents of the patent application are hereby incorporated by reference herein in its entirety.

TECHNICAL FIELD
[001] The disclosed subject matter relates generally to device for respiratory assistance. More particularly, the present disclosure relates to a portable respiratory support device to titrate oxygen content for reducing inappropriate use of oxygen.

BACKGROUND
[002] Non-invasive patient respiratory support devices are used in a variety of medical procedures such as emergency ventilation, anesthesia delivery, and recovery, aerosolized medication delivery, augmentation of natural breathing, supplemental oxygen delivery, mechanical ventilation, weaning from mechanical ventilation and for treating obstructive sleep apnea. Hence, there is a need for a minimally obtrusive nasal mask and ventilation system that delivers mechanical ventilator support or positive airway pressure, and which unencumbers the patient. Currently, non-invasive respiratory therapy with the help of a compressed air source, a compressed oxygen source, a blender and a humidifier is being used to supply heated and humidified, titrated oxygen to the patient. The modalities in non-invasive ventilation include continuous positive airway pressure (CPAP), bi-level airway pressure (BiPAP), high flow nasal oxygenation (HFNO) and Non invasive ventilation systems. HFNO (often referred to as high-flow) systems are broadly defined as systems that provide an oxygen-gas mixture at flows that meet or exceed a patient’s spontaneous inspiratory effort. Traditionally, oxygen delivered via nasal cannula has required low flow rates, thus limiting the amount of supplemental oxygen that can be delivered. In adults, flow rates > 6 L/min are generally not recommended. This is primarily due to limitations in the ability to humidify oxygen at higher flows, leading to the drying of mucous membranes and general patient discomfort. It is generally taught that low-flow nasal cannulas can increase the fraction of inspired oxygen (FIO2) from 0.21 (room air) to perhaps 0.30-0.45 at most. However, subsequent research has shown that these estimates are overly optimistic, extremely variable, and widely fluctuate with increasing inspiratory flow rates. High inspiratory flow rates decrease inspired FIO2 because more room air is entrained, diluting the supplemental oxygen being provided via the nasal cannula. HFNO improves the fraction of inspired oxygen, washes and reduces dead space, generates positive end-expiratory pressure (PEEP) and provides more comfort than cold and dry oxygen.HFNO minimizes the entrainment of room air and subsequently increases the FiO2. Heating and humidifying the oxygen allows high flows to be tolerated and is addressed via specialized equipment capable of mixing oxygen with heated water vapor. Finally, compared to other devices such as non-invasive ventilation (NIV), the tolerance of HFNO may be higher due to its interface, as simple nasal prongs enable patients to speak, eat and drink.

[003] In the absence of a blender and a compressed air source, inappropriate oxygen delivery in the non-invasive respiratory therapy is causing slow damage to the brain, eye, and gut especially in neonates due to delivery of inappropriate content of oxygen. The alternative non-invasive ventilators or mechanical ventilators are priced exorbitantly high and are high on operation cost.

[004] The non-invasive therapies such as the CPAP or HFNO need several complementary infrastructures such as the centralized compressed sources, blenders, humidifiers that add more to the operational cost. These instruments are heavy and cannot be used in the transport scenario as well. The availability of these therapies is also restricted to ICU’s in tertiary care centers. Hence, there is a need to design a stand alone portable respiratory support device to reduce inappropriate use of oxygen delivery to the patient in respiratory distress and to improve the quality and efficacy of the existing respiratory support.

[005] In the light of aforementioned discussion, there exists a need for a device and method that would overcome or ameliorate the above-mentioned limitations.

SUMMARY
[006] The following presents a simplified summary of the disclosure in order to provide a basic understanding of the reader. This summary is not an extensive overview of the disclosure and it does not identify key/critical elements of the invention or delineate the scope of the invention. Its sole purpose is to present some concepts disclosed herein in a simplified form as a prelude to the more detailed description that is presented later.

[007] An objective of the present disclosure is directed towards reducing inappropriate use of oxygen delivery to the patient in respiratory distress and to improve quality and efficacy of the respiratory support.

[008] Another objective of the present disclosure is directed towards titrating the oxygen content (Fraction of inspired oxygen, FiO2) based on the requirement for the patient.

[009] Another objective of the present disclosure is directed towards facilitating the device to use an inbuilt air compressor/air pump and air blender with an anti-bacterial filter inlet.

[0010] Another objective of the present disclosure is directed towards facilitating to reach among the patients with respiratory distress in primary and secondary health care centers where centralized compressed oxygen or compressed air cylinders or the air compressor’s availability is low.

[0011] Another objective of the present disclosure is directed towards reducing the dependency on electricity and operates on a rechargeable battery.

[0012] Another objective of the present disclosure is directed towards serving for a predetermined time (for example, 72 hours) of continuous operation on a single It can run directly from electricity also. The same device can be used recurrently for at least three years.

[0013] Another objective of the present disclosure is directed towards reducing the chance of spreading the infection by compressing the air internal to the device with a replaceable anti-bacterial filter.

[0014] Another objective of the present disclosure is directed towards facilitating to use in multiple modes such as High flow nasal oxygenation and CPAP use in the labor room, T piece, CPAP and HFNO use during transport and for use of T piece, CPAP and High Flow nasal oxygenation device in the hospital settings

[0015] Another objective of the present disclosure is directed towards functioning as a ventilator with the attachment of an automated dual valve.

[0016] Another objective of the present disclosure is directed towards providing much higher flows (up to 30, 40, or 60 and 80L/min) in an attempt to match or exceed the subject (patient’s) inspiratory flow by the high flow nasal cannula device (HFNC). Heating and humidifying the oxygen allows high flows to be tolerated and is addressed via specialized equipment capable of mixing oxygen with heated water vapor.

[0017] According to an exemplary aspect, a portable respiratory support device to titrate oxygen content for reducing inappropriate use of oxygen.

[0018] According to exemplary aspect, a processing device configured to supply titrate oxygen from 21% to 100% based on the requirement of a subject, a calculator configured to calculate the required oxygen flow and airflow to achieve the suggested fraction of inspired oxygen percentage and overall flow rate.

[0019] According to another exemplary aspect, a control system configured to monitor the parameters required for high flow therapy such as the continuous pressure delivered to patient, percentage of oxygen delivered, flow rate delivered and inspiration and expiration rates, battery level, errors, malfunctions and alarms.

[0020] According to another exemplary aspect, an air compressor configured to deliver upto 80L/min and an air blender inbuilt configured to blend oxygen supplied through external oxygen cylinder with the air supplied by the air compressor, the inbuilt air compressor comprising an anti-bacterial filter inlet.

[0021] According to another exemplary aspect, a flow meter/regulator operated by a health care worker to adjust the flow rates of oxygen and atmospheric airflow and a display device configured to display the flow rate of desired oxygen and atmospheric airflow to achieve the required the desired FIO2.

[0022] According to another exemplary aspect, a display device is configured to display high flow therapy parameters such as the continuous pressure delivered to patient, percentage of oxygen delivered, flow rate delivered and inspiration and expiration rates, battery level, malfunctions or errors, alarms.

BRIEF DESCRIPTION OF THE DRAWINGS
[0023] In the following, numerous specific details are set forth to provide a thorough description of various embodiments. Certain embodiments may be practiced without these specific details or with some variations in detail. In some instances, certain features are described in less detail so as not to obscure other aspects. The level of detail associated with each of the elements or features should not be construed to qualify the novelty or importance of one feature over the others.

[0024] FIG. 1 is a block diagram representing an example environment in which aspects of the present disclosure can be implemented. Specifically, FIG. 1 depicts a schematic representation of a portable respiratory support device to titrate oxygen content for reducing inappropriate use of oxygen.

[0025] FIG. 2A, FIG. 2B, FIG. 2C are example diagrams depicting the display device 102, in accordance with one or more exemplary embodiments.

[0026] FIG. 3 is a diagram depicting the portable respiratory support device with a flow meter 108 as shown in FIG. 1, in accordance with one or more exemplary embodiments.

[0027] FIG. 4 is a diagram depicting the oxygen cylinder 106 as shown in FIG. 1, in accordance with one or more exemplary embodiments.

[0028] FIG. 5A, FIG. 5B are example diagrams depicting the portable respiratory support device, in accordance with one or more exemplary embodiments.

[0029] FIG. 6 is a flowchart depicting an exemplary method to titrate oxygen content for reducing inappropriate use of oxygen, in accordance with one or more exemplary embodiments.

[0030] FIG. 7A is an example diagram depicting a system to titrate oxygen content for reducing inappropriate use of oxygen as shown in FIG. 1, in accordance with one or more exemplary embodiments.

[0031] FIG. 7B is a diagram depicting the portable respiratory support device as shown in FIG. 7A, in accordance with one or more exemplary embodiments.

[0032] FIG. 8 is a block diagram illustrating the details of a digital processing system in which various aspects of the present disclosure are operative by execution of appropriate software instructions.

DETAILED DESCRIPTION OF EXAMPLE EMBODIMENTS
[0033] It is to be understood that the present disclosure is not limited in its application to the details of construction and the arrangement of components set forth in the following description or illustrated in the drawings. The present disclosure is capable of other embodiments and of being practiced or of being carried out in various ways. Also, it is to be understood that the phraseology and terminology used herein is for the purpose of description and should not be regarded as limiting.

[0034] The use of “including”, “comprising” or “having” and variations thereof herein is meant to encompass the items listed thereafter and equivalents thereof as well as additional items. The terms “a” and “an” herein do not denote a limitation of quantity, but rather denote the presence of at least one of the referenced item. Further, the use of terms “first”, “second”, and “third”, and the like, herein do not denote any order, quantity, or importance, but rather are used to distinguish one element from another.

[0035] Referring to FIG. 1, FIG. 1 is a block diagram 100 representing an example environment in which aspects of the present disclosure can be implemented. Specifically, FIG. 1 depicts a schematic representation of a portable respiratory support device to titrate oxygen content for reducing inappropriate use of oxygen. The portable respiratory support device 100 reduces inappropriate use of oxygen delivery to a subject in respiratory distress and to improve quality and efficacy of the respiratory support. The subject may include, but not limited to, a patient. The portable respiratory support device 100 may be used to titrate the oxygen content based on the requirement for the patient. The portable respiratory support device 100 may use an inbuilt air compressor with an anti-bacterial and anti -viral filter inlet. The anti-bacterial and anti -viral filter inlet may be a standard HEPA Filter and this filter is replaceable and it is connected to the input of compressor.

[0036] The HEPA filter is designed to target very small particles, and therefore doesn’t work like a typical membrane filter, where particles larger than a given pore size of a filter are captured. Instead, HEPA filters rely on a combination of three mechanisms to trap particles. The first mechanism is interception, where particles being carried in the airflow around the filter fibers adhere to the filter. Particles must be within one radius of the filter fiber to be captured. Larger particles are often captured by the second mechanism, impaction. Due to their size, these particles cannot adjust to sudden changes in airflow around the filter and essentially run into the filter fiber and become embedded. The final mechanism is diffusion that occurs because of the way microscopic particles move and interact with surrounding molecules. This is described as Brownian motion, where molecules move in a random, zig-zag pattern because they collide with surrounding molecules. This motion slows down a particle’s path through the HEPA filter and increases the probability that the particle will be captured by either interception or impaction.

[0037] The portable respiratory support device 100 may reach among subjects with respiratory distress in primary and secondary health care centers where centralized compressed oxygen or the cylinder’s availability is low. This portable respiratory support device 100 operates on a rechargeable battery with one charge serving up to 72 hours of continuous operation, hence reducing the dependency on electricity and can also run on direct electricity . Since the air is compressed internal to portable respiratory support device 100 with replaceable anti-bacterial and anti- viral filter, the chances of infection spread are low. An ICU settings machine along with a humidifier may replace portable respiratory support device 100 because of low cost and portability. Because of the customizable titration and portability, this portable respiratory support device 100 may be used in multiple modes such as high flow nasal cannula device 113 and T piece in ICU settings, CPAP in clinical settings, and resuscitation support for neonates and adults in transport also. The portable respiratory support device 100 automatically calculates the required flow rates to achieve desired FIO2 and informs an operator regarding the individual flow rates of both oxygen and atmospheric air. The high flow nasal cannula device (HFNC) 113 configured to provide much higher flows (up to 30, 40, or 60 L/min and 80 L/min) in an attempt to match or exceed the subject (patient’s) inspiratory flow. Heating and humidifying the oxygen allows high flows to be tolerated and is addressed via specialized equipment capable of mixing oxygen with heated water vapor.

[0038] The portable respiratory support device 100 includes a display device 102, a keypad 104, a processing device (not shown), an oxygen cylinder 106a, an air pump 106b, a flow meter 108, a pressure regulator 110, and a pressure sensor 112. Pressure relief valve/Bleeder circuit 116, Oxygen content sensor and Flow rate sensor 114. Patients required a total inspiration rate and the required fractional inspired oxygen (fio2) rate may be clinically suggested by the doctor based on blood oxygenation levels of the patient. The oxygen flow and the atmospheric airflow rate are to be calculated based on the Fio2 and the inspiration rate. Based on the below formula,

Oxygen Flow Rate = (Fio2 -21)* Total Inspiration Rate/79
Air Flow Rate= Total Inspiration Rate - Oxygen Flow Rate

[0039] The output of the portable respiratory support device 100 may give the gas with required fio2 percentage. The output may be then passed through a humidifier before it reaches the subject. T Piece is another method of supplying titrated oxygen to the subject. It supplies gas at varying pressures which may be regulated at subject’s end manually. The output of the portable respiratory support device 100 consisting of gas may be sent to the humidifier and in turn is sent to the subject via a bubbling chamber. Gas pressure depends on the expiration and inspiration pressures of the subject. The pressure sensor 112 may be configured to detect the difference in the pressure level between the nasal passages of the subject and transmits a control signal to the processing device. The pressure sensor 112 may be configured to detect the difference in the inhalation pressure in the nasal passages. The processing device 702 may be configured to adjust the delivery of oxygen supply to the nasal passages of the subject by receiving the control signal from the pressure sensor 112. The oxygen content sensor and flow rate sensor 114 may be configured to monitor the flow of oxygen content and flow rate.

[0040] Referring to FIG. 2A-2C, FIG. 2A, FIG. 2B, FIG. 2C are example diagrams 200a, 200b, 200c depicting the display device 102, in accordance with one or more exemplary embodiments. The display device 102 may be configured to display the flow rate 201 to be supplied to the subject has to be input into the display device 102 using the keypad 104. The health worker has to simply type in the required total flow rate 201 from the doctor’s prescription. The input flow rate may include 40 liters.

[0041] As shown in diagram 200b, a fraction of inspired oxygen 203 may be input into the display device 102 using the keypad 104. The fio2 percentage 203 may be mentioned by the doctor in his prescription. The input Fio2 203 percentage may include 25%.

[0042] Based on the inputs of inspired flowrate 201 and the Fio2 % 203 may be fed into the portable respiratory support device 100, the internal processing device (not shown) may be configured to calculate the required oxygen and the airflow rates to be given to the subject. The calculation may be done using the formulas. Once the calculation is completed the oxygen and air 205 may be displayed on the display device 102. Using these readings the health worker may easily calibrate the portable respiratory support device 100 to deliver desired flow rate and inspired oxygen 205. The oxygen and air may include 2L and 38L (rounded off to the whole number).

[0043] Referring to FIG. 3, FIG. 3 is a diagram 300 depicting the flow meter/regulator 108 as shown in FIG. 1, in accordance with one or more exemplary embodiments. The diagram 300 includes a portable respiratory support device 301 , the display device 102, the flow meter/regulator 108, and the nozzle 302. Based on the flow rates noted from the display device 102, the health care worker/doctor may easily adjust the flow meter 108 manually. The flow rate range may be mentioned on the scale and the water level or the float level in the scale may be indicative of the adjusted flow rate. An easily adjustable knob may be arranged on to the device to adjust this reading. The portable respiratory support device 301 may include a bleeder circuit/pressure valve 116 configured to release excess pressure caused due to flow restriction of the flow meter 108.

[0044] Referring to FIG. 4 is a diagram 400 depicting the oxygen cylinder 106 as shown in FIG. 1, in accordance with one or more exemplary embodiments. The oxygen source may be usually external cylinder 106 or a centralized oxygen source based on the infrastructure available within the ecosystem. In the hospital ecosystem the oxygen cylinder 106 has their exclusive flow meters and there is a knob to adjust the flow rate. The health worker/doctor may easily adjust the flow rate based on the readings from the display device 102.

[0045] Referring to FIG. 5A, FIG. 5B, FIG. 5A, FIG. 5B are example diagrams depicting the portable respiratory support device, in accordance with one or more exemplary embodiments. The output from the oxygen cylinder 106 may be connected to the portable respiratory support device 301 using the nozzle 302. The air pump (not shown) may be arranged internal to the portable respiratory support device 301. The flow from both the sources may be blended within the system and it is directed towards the output.

[0046] The output flow may be connected to a user interface (for example, patient interface) may include, but not limited to, a nasal cannula, a face mask, and the like. The pressure at the output may be monitored and there may be pressure valve 116 provided to regulate the output air pressure. The pressure valve 116 may be adjusted to maintain the output pressure at predetermined values. The predetermined values may ranging from 4 to 20 cm H20. However, in cases where humidification may be needed the output first passes through an external humidifier circuit (not shown) before entering the patient interface. The user interface which automatically calculates the required flow rates and informs the operator regarding the individual flow rates of both oxygen and atmospheric air.

[0047] Referring to FIG. 6, FIG. 6 is a flowchart 600 depicting an exemplary method to titrate oxygen content for reducing inappropriate use of oxygen, in accordance with one or more exemplary embodiments. As an option, the method 600 is carried out in the context of the details of FIG. 1, FIG. 2A, FIG. 2B, FIG. 2C, FIG. 3, FIG. 4, and FIG.5A, FIG. 5B. However, the method 600 is carried out in any desired environment. Further, the aforementioned definitions are equally applied to the description below.

[0048] The method commences at step 602, inputting flow rate in a display device through a keypad and then inputting inspired oxygen (fio2 percentage) using the keypad. Thereafter, at step 604, calculating the required oxygen and the airflow rates to be given to a subject by an internal processing device based on the inputs. Thereafter, at step 606, displaying desired oxygen and airflow rates on the display device. Thereafter, at step 608, adjusting a flow meter manually based on the displayed flow rates on the display device. Thereafter, at step 610, connecting an output flow from an oxygen cylinder to a respiratory support device using a nozzle. Thereafter, at step 612, blending the output flow from the cylinder and the internal air pump and directing the output flow towards a subject interface. Thereafter, at step 614, monitoring the pressure at the output flow and adjusting the pressure valve to maintain the output air pressure from 4 to 20 cm H20. Thereafter, at step 616, calculating the oxygen consumption by the subject and the health center in total and generates alerts to the management and the duty doctor

[0049] Referring to FIG. 7A is an example diagram 700a depicting a system to titrate oxygen content for reducing inappropriate use of oxygen as shown in FIG. 1, in accordance with one or more exemplary embodiments. The diagram 700a includes the portable respiratory support device 301, a processing device 702, a network 704, a central database 706, a first computing device 708a, a second computing device 708b, a respiration-monitoring module 710, and a cloud server 712. The portable respiratory support device 301 may be configured to provide titrated oxygen of 21% to 100% to the user. The portable respiratory support device 301 may be configured to obtain subject data and delivers to the central database 706 over the network 704. The subject data may include, but not limited to, oxygen concentration delivered to the patient, output pressure of oxygen and airflow delivered to the patient, and so forth. The portable respiratory support device 301 may be configured to calculate the oxygen consumption by the patient and the health center in total and generates alerts to the management and the duty doctor. The portable respiratory support device 301 may be configured to provide over the air firmware updates. The portable respiratory support device 301 may also be configured to send self-diagnostics report to the cloud server 712. The doctors, management, nurse, specialist, surgeons, health care worker and so forth may operate the first computing device 708a. Patients/subject, family members, relatives, friends, neighbors may operate the second computing device 708b. The portable respiratory support device 301 may be configured to send alerts to the first and second computing device 708a, 708b over the network 704. The alerts may include, but not limited to blockage in air delivery to patient, pressure drop increase in air delivered to patient, blockage in oxygen delivery from the cylinder, decrease in pressure from oxygen cylinder, oxygen cylinder empty or about to finish, malfunction with the compressor, blender malfunction, pressure valve malfunction, input filter malfunction and so forth.

[0050] The portable respiratory support device 301 may be configured to provide a rechargeable battery backup facility to run in case of power cuts and automatically switches back to supply when power is back. The portable respiratory support device 301 may includes a facility to charge the battery from power supply. The portable respiratory support device 301 may be configured to generate alarms for any exceptional behaviours. The behaviours may include, but not limited to, a malfunction with the internal components, lack of oxygen input or reduction in oxygen input to the portable respiratory support device, blockage in air delivery to the patient, pressure drop or increase in air delivered to the patient, blockage in oxygen delivery from the cylinder, decrease in pressure from oxygen cylinder, oxygen cylinder empty or about to finish, a malfunction with the air compressor, a malfunction with the air blender, pressure valve 116 malfunction, input filter malfunction and so forth. The portable respiratory support device 301 may be configured to deliver the oxygen concentration to the patient monitoring facility. The portable respiratory support device 301 may be configured to adjust the flow rate automatically based on the user expiratory pressure. The portable respiratory support device 301 may be configured to provide the facility to adjust the output pressure delivered to the patient. The portable respiratory support device 301 may be connected to the cloud server over the network 704.

[0051] Although the first computing devices 708a, 708b, is shown in FIG. 7A, an embodiment of the system 700a may support any number of computing devices. The first and second computing devices 708a and 708b may include, but not limited to, a desktop computer, a personal mobile computing device such as a tablet computer, a laptop computer, or a netbook computer, a smartphone, backend servers hosting database and other software, and the like. Each computing device supported by the system 700a is realized as a computer-implemented or computer-based device having the hardware or firmware, software, and/or processing logic needed to carry out the intelligent messaging techniques and computer-implemented methodologies described in more detail herein.

[0052] The network 704 may include but not limited to, an Internet of things (IoT network devices), a wireless local area network (WLAN), or a wide area network (WAN), a Bluetooth low energy network, a ZigBee network, a WIFI communication network e.g., the wireless high speed internet, or a combination of networks, a cellular service such as a 4G (e.g., LTE, mobile WiMAX) or 5G cellular data service, a RFID module, a NFC module, wired cables, such as the world-wide-web based Internet, a General Packet Radio Service, a Broadband or other types of networks may include Transport Control Protocol/Internet Protocol (TCP/IP) or device addresses (e.g. network-based MAC addresses, or those provided in a proprietary networking protocol, such as Modbus TCP, or by using appropriate data feeds to obtain data from various web services, including retrieving XML data from an HTTP address, then traversing the XML for a particular node) and so forth without limiting the scope of the present disclosure. The first computing device 708a may be operated by the doctors, health workers, specialists, surgeons, and so forth.

[0053] The respiration monitoring module 710 may be downloaded from the cloud server 712. For example, the respiration monitoring module 710 may be any suitable application downloaded from, GOOGLE PLAY® (for Google Android devices), Apple Inc.'s APP STORE® (for Apple devices, or any other suitable database). In some embodiments, the respiration monitoring module 710 may be software, firmware, or hardware that is integrated into the first computing device and the second computing device 708a and 708b. The respiration monitoring module 710 which is accessed as mobile applications, web applications, software that offers the functionality of accessing mobile applications, and viewing/processing of interactive pages, for example, are implemented in the first and the second computing devices 708a and 708b as will be apparent to one skilled in the relevant arts by reading the disclosure provided herein

[0054] Referring to FIG. 7B is a diagram 700b depicting the portable respiratory support device 507 as shown in FIG. 7A, in accordance with one or more exemplary embodiments. The diagram 700b includes the portable respiratory support device 301, the processing device 702, a calculator 714, a control system 716, an air compressor 718, an air blender 720, the display device 102, the keypad 104, the flow meter 108, the pressure regulator 110, and the pressure sensor 112. The processing device 702 may include, but is not limited to, a microcontroller (for example ARM 7 or ARM 11), a microprocessor, a digital signal processor, a microcomputer, a field programmable gate array, a programmable logic device, a state machine or a logic circuitry.

[0055] The processing device 702 may be configured to calculate the required oxygen and the airflow rates to be given to the subject. The calculator 712 may be configured to determine the required oxygen flow and airflow to achieve the suggested fraction of inspired oxygen percentage and overall flow rate. The control system 716 may be configured to monitor the parameters required for high flow therapy. The parameters may include, the continuous pressure delivered to patient, percentage of oxygen delivered, flow rate delivered and inspiration and expiration rates, battery level, Errors and malfunctions, alarms. Any malfunction with internal components, Lack of oxygen input or reduction in oxygen input to the portable respiratory support device. Alarms include blockage in air delivery to patient ,pressure drop increase in air delivered to patient, blockage in oxygen delivery from the cylinder, decrease in pressure from oxygen cylinder, oxygen cylinder empty or about to finish, mal function with the compressor, blender malfunction, pressure valve malfunction, input filter malfunction and more

[0056] The air compressor 718 may be configured to deliver upto 80L/min. The air blender 720 may be configured to blend oxygen with the air supplied by the air compressor 718. The flow meter 108 may be operated by the health care worker/doctor to adjust the flow rates. The display device 102 may be configured to display desired oxygen and atmospheric air flow rate. The pressure regulator 110 may be configured to control and reduce the pressure of the output flow of the portable air oxygen device for safe and steady fluid delivery to the subject. The pressure regulator 110 may be configured to control and reduce the pressure of the flow output from the device for safe and steady fluid delivery to the subject.

[0057] The processing device 702 may be configured to adjust the delivery of oxygen supply to the nasal passages of the subject by receiving the control signal from the pressure sensor. The processing device 702 may be configured to monitor oxygen left to be used in the oxygen cylinder attached to the portable respiratory support device and generates alerts to the management and the duty doctor. The processing device 702 configured to receive over the air firmware updates and send self-diagnostics report to the cloud server 712. The flow meter/regulator 108 configured to adjust the flow rate of oxygen and atmospheric air automatically based on the subject’s expiratory pressure and a display device configured to display pressure delivered to patient, percentage of oxygen delivered, flow rate delivered and inspiration and expiration rates, battery level, Errors and malfunctions, alarms required for high flow therapy

[0058] Referring to FIG. 8 is a block diagram 800 illustrating the details of a digital processing system 800 in which various aspects of the present disclosure are operative by execution of appropriate software instructions. The Digital processing system 800 may correspond to the computing devices 708a, 708b (or any other system in which the various features disclosed above can be implemented).

[0059] Digital processing system 800 may contain one or more processors such as a central processing unit (CPU) 810, random access memory (RAM) 820, secondary memory 830, graphics controller 860, display unit 870, network interface 880, and input interface 890. All the components except display unit 870 may communicate with each other over communication path 850, which may contain several buses as is well known in the relevant arts. The components of Figure 8 are described below in further detail.

[0060] CPU 810 may execute instructions stored in RAM 820 to provide several features of the present disclosure. CPU 810 may contain multiple processing units, with each processing unit potentially being designed for a specific task. Alternatively, CPU 810 may contain only a single general-purpose processing unit.

[0061] RAM 820 may receive instructions from secondary memory 830 using communication path 850. RAM 820 is shown currently containing software instructions, such as those used in threads and stacks, constituting shared environment 825 and/or user programs 826. Shared environment 825 includes operating systems, device drivers, virtual machines, etc., which provide a (common) run time environment for execution of user programs 826.

[0062] Graphics controller 860 generates display signals (e.g., in RGB format) to display unit 870 based on data/instructions received from CPU 810. Display unit 870 contains a display screen to display the images defined by the display signals. Input interface 890 may correspond to a keyboard and a pointing device (e.g., touch-pad, mouse) and may be used to provide inputs. Network interface 880 provides connectivity to a network (e.g., using Internet Protocol), and may be used to communicate with other systems (such as those shown in Figure 1) connected to the network 704.

[0063] Secondary memory 830 may contain hard drive 835, flash memory 836, and removable storage drive 837. Secondary memory 830 may store the data software instructions (e.g., for performing the actions noted above with respect to the Figures), which enable digital processing system 800 to provide several features in accordance with the present disclosure.

[0064] Some or all of the data and instructions may be provided on removable storage unit 840, and the data and instructions may be read and provided by removable storage drive 837 to CPU 810. Floppy drive, magnetic tape drive, CD-ROM drive, DVD Drive, Flash memory, removable memory chip (PCMCIA Card, EEPROM) are examples of such removable storage drive 837.

[0065] Removable storage unit 840 may be implemented using medium and storage format compatible with removable storage drive 837 such that removable storage drive 837 can read the data and instructions. Thus, removable storage unit 840 includes a computer readable (storage) medium having stored therein computer software and/or data. However, the computer (or machine, in general) readable medium can be in other forms (e.g., non-removable, random access, etc.).

[0066] In this document, the term "computer program product" is used to generally refer to removable storage unit 840 or hard disk installed in hard drive 835. These computer program products are means for providing software to digital processing system 800. CPU 810 may retrieve the software instructions, and execute the instructions to provide various features of the present disclosure described above.

[0067] The term “storage media/medium” as used herein refers to any non-transitory media that store data and/or instructions that cause a machine to operate in a specific fashion. Such storage media may comprise non-volatile media and/or volatile media. Non-volatile media includes, for example, optical disks, magnetic disks, or solid-state drives, such as storage memory 830. Volatile media includes dynamic memory, such as RAM 820. Common forms of storage media include, for example, a floppy disk, a flexible disk, hard disk, solid-state drive, magnetic tape, or any other magnetic data storage medium, a CD-ROM, any other optical data storage medium, any physical medium with patterns of holes, a RAM, a PROM, and EPROM, a FLASH-EPROM, NVRAM, any other memory chip or cartridge.

[0068] Storage media is distinct from but may be used in conjunction with transmission media. Transmission media participates in transferring information between storage media. For example, transmission media includes coaxial cables, copper wire and fiber optics, including the wires that comprise bus (communication path) 850. Transmission media can also take the form of acoustic or light waves, such as those generated during radio-wave and infra-red data communications.

[0069] Reference throughout this specification to “one embodiment”, “an embodiment”, or similar language means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the present disclosure. Thus, appearances of the phrases “in one embodiment”, “in an embodiment” and similar language throughout this specification may, but do not necessarily, all refer to the same embodiment.

[0070] Although the present disclosure has been described in terms of certain preferred embodiments and illustrations thereof, other embodiments and modifications to preferred embodiments may be possible that are within the principles and spirit of the invention. The above descriptions and figures are therefore to be regarded as illustrative and not restrictive.

[0071] Thus the scope of the present disclosure is defined by the appended claims and includes both combinations and sub-combinations of the various features described herein above as well as variations and modifications thereof, which would occur to persons skilled in the art upon reading the foregoing description.
,CLAIMS:We Claim:
1. A portable respiratory support device to titrate oxygen content for reducing inappropriate use of oxygen, comprising:

a processing device configured to supply titrate oxygen from 21% to 100% based on the requirement of a subject, the processing device configured to calculate a flow rate regarding individual flow rates of oxygen and atmospheric air;

a control system configured to monitor one or more parameters such as the continuous pressure delivered to patient, percentage of oxygen delivered, flow rate delivered and inspiration and expiration rates, battery level, Errors and malfunctions, alarms required for high flow therapy; a calculator configured to determine the oxygen flow and atmospheric airflow to achieve the suggested fraction of inspired oxygen percentage and overall flow rate; Any malfunction with internal components, Lack of oxygen input or reduction in oxygen input to the portable respiratory support device. Alarms include blockage in air delivery to patient ,pressure drop increase in air delivered to patient, blockage in oxygen delivery from the cylinder, decrease in pressure from oxygen cylinder, oxygen cylinder empty or about to finish, mal function with the compressor, blender malfunction, pressure valve malfunction, input filter malfunction and more

an air compressor configured to deliver up to 80 litters per minute and an internal air blender configured to blend oxygen with the air supplied by the air compressor, the air compressor comprising an anti-bacterial and anti-viral filter inlet; and

a flow regulator configured to adjust the flow rate of oxygen and atmospheric air automatically based on the subject’s expiratory pressure and a display device configured to display pressure delivered to patient, percentage of oxygen delivered, flow rate delivered and inspiration and expiration rates, battery level, Errors and malfunctions, alarms required for high flow therapy

2. The portable respiratory support device as claimed in claim 1, wherein the processing device is configured to deliver the subject data to a central database.

3. The portable respiratory support device as claimed in claim 1, comprising a keypad configured to enable the health worker to input the flow rate of the inspired oxygen and atmospheric airflow to be supplied to the subject.

4. The portable respiratory support device as claimed in claim 1, comprising a pressure regulator configured to control and reduce the pressure of the flow output from the device for safe and steady fluid delivery to the subject.

5. The portable respiratory support device as claimed in claim 1, comprising a pressure sensor configured to sense an inhalation pressure from both the right and left nasal passages of the subject.

6. The portable respiratory support device as claimed in claim 5, wherein the pressure sensor is configured to transmit a control signal to the processing device by detecting the difference in the inhalation pressure in nasal passages.

7. The portable respiratory support device as claimed in claim 1, wherein the processing device is configured to adjust the delivery of oxygen supply to the nasal passages of the subject by receiving the control signal from the pressure sensor.

8. The portable respiratory support device as claimed in claim 1, wherein the processing device is configured to monitor oxygen left to be used in the oxygen cylinder attached to the portable respiratory support device and generates alerts to a first computing device.

9. The portable respiratory support device as claimed in claim 1, wherein the processing device is configured to receive over the air firmware updates and send a self-diagnostics report to a cloud server.

10. The portable respiratory support device as claimed in claim 1, wherein the flow regulator is operated by the health worker to adjust the flow rates of oxygen and atmospheric air.

11. The portable respiratory support device as claimed in claim 1, comprising a pressure valve configured to adjust output pressure of oxygen at predetermined values.

12. The portable respiratory support device as claimed in claim 1, comprising a high flow nasal cannula device (HFNC) configured to provide much higher flows (up to 30, 40, or 60 L/min and 80L/min) which improves Fio2, reduces dead space by carbon dioxide clearance and generates positive end expiratory pressure.

13. A method for titrating oxygen content to reduce inappropriate use of oxygen, comprising:

inputting flow rate in a display device through a keypad and then inputting inspired oxygen (fio2 percentage) using the keypad by a health worker;

calculating the required oxygen and the airflow rates to be given to a subject by a processing device based on the inputs of the flow rate provided by the health worker to the keypad;

displaying desired oxygen and atmospheric airflow rates on the display device;

adjusting a flow meter manually based on the displayed flow rates on the display device;

connecting an output flow from an oxygen cylinder to a respiratory support device using a nozzle;

blending the output flow from the oxygen cylinder and the internal air pump and directing the output flow towards a subject interface by a pressure sensor, a flow sensor and an oxygen sensor ;

monitoring the pressure at the output flow and adjusting a pressure valve to maintain the output air pressure at predetermined values; and

calculating the oxygen consumption by the subject and the health center in total and generates alerts to the management and the duty doctor.