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Process For Production Of Nucleoside Compound
In reacting pentose-1-phosphoric acid with a nucleic acid base or a nucleic acid base analogue in an aqueous reaction medium in the presence of a metal cation to produce a nucleoside compound, the timing or method of addition of at least one of these components to the aqueous reaction medium is varied; thereby, a nucleoside compound can be produced at a high yield efficiently without inviting the high viscosity or solidification of the reaction mixture, even when the above components are used in such amounts that the reaction mixture becomes highly viscous or is solidified when the components are used without the above variation of the addition timing or method. Thus, there can be provided a process for producing a nucleoside compound, which comprises a step of reacting pentose-1-phosphoric acid with a nucleic acid base or a nucleic acid base analogue in the presence of nucleoside phosphorylase activity, which gives a nucleoside compound at an improved conversion, and which has wide applicability.
Notices, Deadlines & Correspondence
Patent Information
Applicants
MITSUI CHEMICALS, INC.
Inventors
1. ARAKI TADASHI
2. IKEDA ICHIRO
3. TAKAHASHI KATSUYUKI
4. ITO KIYOSHI
5. ASANO TAMOTSU
6. NIKUMARU SEIYA
7. NAKAMURA TAKESHI
8. ISHIBASHI HIROKI
9. NAGAHARA KIYOTERU
10. FUKUIRI YASUSHI
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 543-KOLNP-2003-FER-[12-07-2006].pdf | 2006-07-12 |
| 2 | 543-KOLNP-2003-LETTER OF PATENT CERTIFICATE-[07-05-2008].pdf | 2008-05-07 |
| 3 | 543-kolnp-2003-granted-translated copy of priority document.pdf | 2011-10-06 |
| 4 | 543-kolnp-2003-granted-specification.pdf | 2011-10-06 |
| 5 | 543-kolnp-2003-granted-reply to examination report.pdf | 2011-10-06 |
| 6 | 543-kolnp-2003-granted-priority document.pdf | 2011-10-06 |
| 7 | 543-kolnp-2003-granted-letter patent.pdf | 2011-10-06 |
| 8 | 543-kolnp-2003-granted-gpa.pdf | 2011-10-06 |
| 9 | 543-kolnp-2003-granted-form 5.pdf | 2011-10-06 |
| 10 | 543-kolnp-2003-granted-form 3.pdf | 2011-10-06 |
| 11 | 543-kolnp-2003-granted-form 2.pdf | 2011-10-06 |
| 12 | 543-kolnp-2003-granted-form 18.pdf | 2011-10-06 |
| 13 | 543-kolnp-2003-granted-form 1.pdf | 2011-10-06 |
| 14 | 543-kolnp-2003-granted-examination report.pdf | 2011-10-06 |
| 15 | 543-kolnp-2003-granted-description (complete).pdf | 2011-10-06 |
| 16 | 543-kolnp-2003-granted-correspondence.pdf | 2011-10-06 |
| 17 | 543-kolnp-2003-granted-claims.pdf | 2011-10-06 |
| 18 | 543-kolnp-2003-granted-abstract.pdf | 2011-10-06 |
| 19 | 543-KOLNP-2003-FORM-27.pdf | 2013-06-15 |
| 20 | 543-KOLNP-2003-(28-03-2016)-FORM-27.pdf | 2016-03-28 |
| 21 | Form 27 [30-03-2017(online)].pdf | 2017-03-30 |
| 22 | 543-KOLNP-2003-RELEVANT DOCUMENTS [27-03-2018(online)].pdf | 2018-03-27 |
| 23 | 543-KOLNP-2003-RELEVANT DOCUMENTS [14-03-2019(online)].pdf | 2019-03-14 |
| 24 | 543-KOLNP-2003-RELEVANT DOCUMENTS [19-03-2020(online)].pdf | 2020-03-19 |
| 25 | 543-KOLNP-2003-FORM-26 [04-01-2021(online)].pdf | 2021-01-04 |
| 26 | 543-KOLNP-2003-RELEVANT DOCUMENTS [20-09-2021(online)].pdf | 2021-09-20 |
| 27 | 543-KOLNP-2003-FORM-26 [27-10-2021(online)].pdf | 2021-10-27 |
| 28 | 543-KOLNP-2003-20-01-2023-ALL DOCUMENTS.pdf | 2023-01-20 |