Abstract: The present invention relates to a process for the preparation of Form 1 of (+)-(S)-α-(2-ChIorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid methyl ester hydrogen sulphate commonly known as Clopidogrel bisulphate. The present invention further relates to a process for reducing the amount of methyl isobutyl ketone and controlling the amount of mesityl oxide in Clopidogrel hydrogen sulphate Form 1 by washing with ethyl acetate.
| # | Name | Date |
|---|---|---|
| 1 | 3511-delnp-2011-Abstract.pdf | 2012-01-17 |
| 1 | 3511-delnp-2011-Form-2.pdf | 2012-01-17 |
| 2 | 3511-delnp-2011-Claims.pdf | 2012-01-17 |
| 2 | 3511-delnp-2011-Form-1.pdf | 2012-01-17 |
| 3 | 3511-delnp-2011-Correspondence-others.pdf | 2012-01-17 |
| 3 | 3511-delnp-2011-Description (Complete).pdf | 2012-01-17 |
| 4 | 3511-delnp-2011-Correspondence-others.pdf | 2012-01-17 |
| 4 | 3511-delnp-2011-Description (Complete).pdf | 2012-01-17 |
| 5 | 3511-delnp-2011-Claims.pdf | 2012-01-17 |
| 5 | 3511-delnp-2011-Form-1.pdf | 2012-01-17 |
| 6 | 3511-delnp-2011-Abstract.pdf | 2012-01-17 |
| 6 | 3511-delnp-2011-Form-2.pdf | 2012-01-17 |