Abstract: The present invention provides a process for preparation of crystalline aprepitant having not more than 15% by weight of Form I content which comprises, a) dissolving aprepitant in a suitable solvent to obtain a solution, b) cooling the solution to 10-15°C, c) optionally seeding the solution with aprepitant Form I crystals, d) adding an anti-solvent to the solution, and e) isolating crystalline aprepitant having not more than 15% by weight of Form I content.
NA
| # | Name | Date |
|---|---|---|
| 1 | 10305-DELNP-2011-AbandonedLetter.pdf | 2019-11-05 |
| 1 | 10305-delnp-2011-Form-2.pdf | 2012-07-24 |
| 2 | 10305-DELNP-2011-FER.pdf | 2017-08-31 |
| 2 | 10305-delnp-2011-Form-1.pdf | 2012-07-24 |
| 3 | 10305-delnp-2011-Drawings.pdf | 2012-07-24 |
| 3 | 10305-delnp-2011-Correspondence Others-(16-05-2013).pdf | 2013-05-16 |
| 4 | 10305-delnp-2011-Form-18-(16-05-2013).pdf | 2013-05-16 |
| 4 | 10305-delnp-2011-Description (Complete).pdf | 2012-07-24 |
| 5 | 10305-delnp-2011-Abstract.pdf | 2012-07-24 |
| 5 | 10305-delnp-2011-Correspondence Others.pdf | 2012-07-24 |
| 6 | 10305-delnp-2011-Claims.pdf | 2012-07-24 |
| 7 | 10305-delnp-2011-Abstract.pdf | 2012-07-24 |
| 7 | 10305-delnp-2011-Correspondence Others.pdf | 2012-07-24 |
| 8 | 10305-delnp-2011-Description (Complete).pdf | 2012-07-24 |
| 8 | 10305-delnp-2011-Form-18-(16-05-2013).pdf | 2013-05-16 |
| 9 | 10305-delnp-2011-Correspondence Others-(16-05-2013).pdf | 2013-05-16 |
| 9 | 10305-delnp-2011-Drawings.pdf | 2012-07-24 |
| 10 | 10305-delnp-2011-Form-1.pdf | 2012-07-24 |
| 10 | 10305-DELNP-2011-FER.pdf | 2017-08-31 |
| 11 | 10305-delnp-2011-Form-2.pdf | 2012-07-24 |
| 11 | 10305-DELNP-2011-AbandonedLetter.pdf | 2019-11-05 |
| 1 | searchstrategy_24-08-2017.pdf |