New Process For The Preparation Of N (1,1 Dimethylethyl) 4 [[5'ethoxy

New Process For The Preparation Of N (1,1 Dimethylethyl) 4 [[5'ethoxy 4 Cis [2 (4 Morfolino)ethoxy] 2' Oxospiro[Cyclohexan 1,3' [H]Indol] 1'(2’h] Yl] Sulfonyl] 3 Methoxybenzamide And Its Salts

Abstract: The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10 °C and 40 °C, preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.

Patent Information

Application #

Filing Date

20 December 2001

Publication Number

15/2007

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Patent Number

Legal Status

Grant Date

2007-11-01

Renewal Date

Applicants

SANOFI-SYNTHELABO

174 AVENUE DE FRANCE, F-75013 PARIS

Inventors

1. GERGELY HEJA

NASZNAGY U.27, H-1131, BUDAPEST

2. EVA CSIKOS

BERCTETO U. 4,H-1038 BUDAPEST

3. TUNDE EROSNE TAKASCY

POSA L.U.24,H-1149 BUDAPEST

4. CSABA GONCZI

LISZNYAI U.5, H-1016 BUDAPEST

5. JUDIT HALASZ

ERDOSOR U.11H-1046 BUDAPEST

6. ISTVAN HERMECZ

REDAY U.32.H-1092

7. CSILLA MAJLATH

ATLOS U.174.H-1204 BUDAPEST

8. LAJOS NAGY

VASARHELYI K.TER 16,H-2000

9. ANDREA SANTANE CSUTOR

FRANKEL L.U.96,H-1023 BUDAPEST

10. PETER SAROSI

ARANY J.U.70,H-1154 BUDAPEST

11. KALMAN SIMON

RATKOC U.9,H-1118 BUDAPEST

12. TIBORNE SZOMOR

ATTILA U. 2,H-1013 BUDAPEST

13. GYORGYNE SZVOBODA

VACZI M.U. 21,H-2120 DUNAKESZI

Specification

FORM 2
THE PATENTS ACT 1970
[39 OF 1970]
COMPLETE SPECIFICATION
[See Section 10]

PR0CESS FOR THE PREPARATION OF N-(l,lrDIMETHYLETHYL)-

OXOSPIRO[GYCLOHEXAN-1,3'[H]INDOL]-1 '(2:H]TYL]^SULFONYL]-3-
METHOXYBENZAMIDE AND ITS SALTS"
SANOFI-SYNTHELABO, of 174, Avenue de France, F-75013 Paris, France, a french company
The following specification particularly describes the nature of the invention and the manner in which it is to be performed :-
original
in/pct/01621/mum

Documents

Application Documents

#	Name	Date
1	in-pct-2001-01621-mum-form 5(20-12-2001).pdf	2001-12-20
2	in-pct-2001-01621-mum-form 3(20-12-2001).pdf	2001-12-20
3	in-pct-2001-01621-mum-form 2(granted)-(20-12-2001).pdf	2001-12-20
4	in-pct-2001-01621-mum-form 1(20-12-2001).pdf	2001-12-20
5	in-pct-2001-01621-mum-petition under rule 137(27-10-2004).pdf	2004-10-27
6	in-pct-2001-01621-mum-form pct-isa-210(27-10-2004).pdf	2004-10-27
7	in-pct-2001-01621-mum-form 3(27-10-2004).pdf	2004-10-27
9	in-pct-2001-01621-mum-form 1a(27-10-2004).pdf	2004-10-27
10	in-pct-2001-01621-mum-claims(granted)-(27-10-2004).pdf	2004-10-27
12	in-pct-2001-01621-mum-cancelled page(27-10-2004).pdf	2004-10-27
13	in-pct-2001-01621-mum-correspondence-ipo-(13-10-2006).pdf	2006-10-13
14	in-pct-2001-01621-mum-power of authority(25-10-2007).pdf	2007-10-25
15	in-pct-2001-01621-mum-correspondence(25-10-2007).pdf	2007-10-25
16	IN-PCT-2001-01621-MUM-CORRESPONDENCE(RENEWAL PAYMENT LETTER)-(22-03-2011).pdf	2011-03-22
17	in-pct-2001-01621-mum-form 19(6-11-2003).pdf	2018-08-08
18	abstract1.jpg	2018-08-08