Process For The Preparation Salts Of Triazole Compounds

Abstract: The present invention discloses a large scale process for preparation of triazole compounds using polar and non-polar solvents. More particularly relates to s method of preparing dilauryl glyceryl fumarate salt of posaconazole, voriconazole and itraconazole respectively. The method comprises of dissolving triazole compound and dilauryl glyceryl fumarate in a suitable polar solvent at a temperature range of 30-55? for salt formation and final salt is isolated using non-polar solvent at a low temperature range of 0-35?. It further discloses a method of producing fine particulate size of the dilauryl glyceryl fumarate salt of triazole preferably in the size ranging from 0.001micron to 100micron. It also discloses a method of preparing a desired pharmaceutical preparation.

Patent Information

Application #

Filing Date

01 November 2022

Publication Number

44/2022

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

sam.thomas@cellixbio.com

Parent Application

Applicants

CELLIX BIO PRIVATE LIMITED

Plot No. 1177 B, Road No. 56 Jubilee Hills Hyderabad 500033

Inventors

1. KANDULA, Mahesh

11-61, East Godavari District G.Medapadu 533434

Specification

Documents

Application Documents

#	Name	Date
1	202247062162.pdf	2022-11-01
2	202247062162-STATEMENT OF UNDERTAKING (FORM 3) [01-11-2022(online)].pdf	2022-11-01
3	202247062162-PROOF OF RIGHT [01-11-2022(online)].pdf	2022-11-01
4	202247062162-PRIORITY DOCUMENTS [01-11-2022(online)].pdf	2022-11-01
5	202247062162-POWER OF AUTHORITY [01-11-2022(online)].pdf	2022-11-01
6	202247062162-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [01-11-2022(online)].pdf	2022-11-01
7	202247062162-FORM FOR SMALL ENTITY(FORM-28) [01-11-2022(online)].pdf	2022-11-01
8	202247062162-FORM 1 [01-11-2022(online)].pdf	2022-11-01
9	202247062162-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [01-11-2022(online)].pdf	2022-11-01
10	202247062162-DECLARATION OF INVENTORSHIP (FORM 5) [01-11-2022(online)].pdf	2022-11-01
11	202247062162-COMPLETE SPECIFICATION [01-11-2022(online)].pdf	2022-11-01
12	202247062162-PROOF OF RIGHT [01-11-2022(online)].pdf	2022-11-01
12	202247062162-Correspondence_Form-1 And Power Of Attorney _24-11-2022.pdf	2022-11-24
13	202247062162-STATEMENT OF UNDERTAKING (FORM 3) [01-11-2022(online)].pdf	2022-11-01
13	202247062162-FORM 3 [18-02-2023(online)].pdf	2023-02-18
14	202247062162.pdf	2022-11-01
14	202247062162-FORM 3 [22-05-2023(online)].pdf	2023-05-22