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Prodrug Of Benzoquinolizine 2 Carboxylic Acid
Abstract: The instant invention relates to novel prodrugs of optically pure benzoquinolizine-2-carboxylic acid, and pharmaceutical compositions that include the prodrugs. In particular, the present invention relates to the sulfonic acid salt of L-alanine and L-valine prodrugs of s- (-) -9- fluoro 6,7-dihydro-8- (4-hydroxypiperidin-1-yl) -5-methy-1-oxo-1H, 5H-benzo[i, j] quinolizine-2-carboxylic acid. The compounds and compositions of the invention can be used to treat bacterial Gram-positive, Gram-negative and anaerobic infections, especially infections caused by resistant Gram-positive organism and Gram-negative organism, mycobacterial infections and emerging nosocomial pathogen infections.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
07 March 2006
Publication Number
43/2007
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2015-07-02
Renewal Date
Applicants
WOCKHARDT LIMITED
WOCKHARDT TOWERS
BANDRA-KURLA COMPLEX
BANDRA-(E)
MUMBAI 400 051,
Inventors
1. MAHESH VITHALBHAI PATEL
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
2. YATI CHUGH
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
3. SHRIKANT VINAYAK GUPTE
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
4. NITIN SHETTY
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
5. VIJAYA NARAYAN DESAI
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
6. PRASAD KESHAV DESHPANDE
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
7. RAVINDRA DATTATRAYA YEOLE
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
8. MAHESH SHRIRAM PHANSALKAR
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
9. MOHAMMAD ALAM JAFRI
WOCKHARDT RESEARCH CENTRE
D-4, MIDC, CHIKALTHANA
AURANGABAD-431 210
Specification
Documents
Orders
| Section | Controller | Decision Date |
|---|---|---|
| 15 | Bharat N S | 2015-07-02 |
| 15 | Bharat N S | 2015-07-02 |
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 321-MUM-2006-CORRESPONDENCE(RENEWAL PAYMENT LETTER)-(07-04-2016).pdf | 2016-04-07 |
| 1 | 321-MUM-2006-RELEVANT DOCUMENTS [19-03-2024(online)].pdf | 2024-03-19 |
| 2 | 321-MUM-2006-RELEVANT DOCUMENTS [23-02-2018(online)].pdf | 2018-02-23 |
| 2 | 321-MUM-2006-RELEVANT DOCUMENTS [29-03-2023(online)].pdf | 2023-03-29 |
| 3 | 321-MUM-2006_EXAMREPORT.pdf | 2018-08-09 |
| 3 | 321-MUM-2006-RELEVANT DOCUMENTS [30-03-2022(online)].pdf | 2022-03-30 |
| 4 | 321-MUM-2006-SPECIFICATION(AMENDED)-(28-4-2015).pdf | 2018-08-09 |
| 4 | 321-MUM-2006-RELEVANT DOCUMENTS [30-03-2021(online)].pdf | 2021-03-30 |
| 5 | 321-MUM-2006-REPLY TO HEARING(28-4-2015).pdf | 2018-08-09 |
| 5 | 321-MUM-2006-RELEVANT DOCUMENTS [11-03-2020(online)].pdf | 2020-03-11 |
| 6 | 321-MUM-2006-REPLY TO EXAMINATION REPORT(16-1-2013).pdf | 2018-08-09 |
| 6 | 321-MUM-2006-RELEVANT DOCUMENTS [14-03-2019(online)].pdf | 2019-03-14 |
| 7 | 321-MUM-2006-PETITION UNDER RULE-137(28-4-2015).pdf | 2018-08-09 |
| 7 | 321-MUM-2006-ABSTRACT(27-2-2007).pdf | 2018-08-09 |
| 8 | 321-MUM-2006-MARKED COPY(28-4-2015).pdf | 2018-08-09 |
| 8 | 321-MUM-2006-ABSTRACT(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 9 | 321-MUM-2006-CLAIMS(AMENDED)-(16-1-2013).pdf | 2018-08-09 |
| 9 | 321-MUM-2006-GENERAL POWER OF ATTORNEY(28-4-2015).pdf | 2018-08-09 |
| 10 | 321-MUM-2006-CLAIMS(AMENDED)-(28-4-2015).pdf | 2018-08-09 |
| 10 | 321-MUM-2006-FORM 5(3-8-2006).pdf | 2018-08-09 |
| 11 | 321-MUM-2006-CLAIMS(AMENDED)-(9-6-2015).pdf | 2018-08-09 |
| 11 | 321-MUM-2006-FORM 5(27-2-2007).pdf | 2018-08-09 |
| 12 | 321-MUM-2006-CLAIMS(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 12 | 321-MUM-2006-FORM 3(7-3-2006).pdf | 2018-08-09 |
| 13 | 321-MUM-2006-CLAIMS(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 13 | 321-MUM-2006-FORM 3(27-2-2007).pdf | 2018-08-09 |
| 14 | 321-MUM-2006-CORRESPONDENCE(13-5-2009).pdf | 2018-08-09 |
| 14 | 321-MUM-2006-FORM 2(TITLE PAGE)-(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 15 | 321-MUM-2006-CORRESPONDENCE(27-2-2007).pdf | 2018-08-09 |
| 15 | 321-MUM-2006-FORM 2(TITLE PAGE)-(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 16 | 321-MUM-2006-CORRESPONDENCE(28-4-2015).pdf | 2018-08-09 |
| 16 | 321-MUM-2006-FORM 2(TITLE PAGE)-(28-4-2015).pdf | 2018-08-09 |
| 17 | 321-MUM-2006-FORM 2(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 17 | 321-MUM-2006-CORRESPONDENCE(31-3-2016).pdf | 2018-08-09 |
| 18 | 321-MUM-2006-CORRESPONDENCE(9-6-2015).pdf | 2018-08-09 |
| 18 | 321-MUM-2006-FORM 2(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 19 | 321-MUM-2006-CORRESPONDENCE(IPO)-(2-4-2007).pdf | 2018-08-09 |
| 19 | 321-MUM-2006-FORM 18(27-4-2009).pdf | 2018-08-09 |
| 20 | 321-MUM-2006-DESCRIPTION(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 20 | 321-MUM-2006-FORM 13--(31-3-2016).pdf | 2018-08-09 |
| 21 | 321-MUM-2006-DESCRIPTION(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 21 | 321-MUM-2006-FORM 13 (31-3-2016).pdf | 2018-08-09 |
| 22 | 321-MUM-2006-DRAWING(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 22 | 321-MUM-2006-FORM 1(7-3-2006).pdf | 2018-08-09 |
| 23 | 321-MUM-2006-FORM 1(27-2-2007).pdf | 2018-08-09 |
| 23 | 321-MUM-2006-FORM 1(28-4-2015).pdf | 2018-08-09 |
| 24 | 321-MUM-2006-FORM 1(28-4-2015).pdf | 2018-08-09 |
| 24 | 321-MUM-2006-FORM 1(27-2-2007).pdf | 2018-08-09 |
| 25 | 321-MUM-2006-DRAWING(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 25 | 321-MUM-2006-FORM 1(7-3-2006).pdf | 2018-08-09 |
| 26 | 321-MUM-2006-DESCRIPTION(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 26 | 321-MUM-2006-FORM 13 (31-3-2016).pdf | 2018-08-09 |
| 27 | 321-MUM-2006-DESCRIPTION(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 27 | 321-MUM-2006-FORM 13--(31-3-2016).pdf | 2018-08-09 |
| 28 | 321-MUM-2006-CORRESPONDENCE(IPO)-(2-4-2007).pdf | 2018-08-09 |
| 28 | 321-MUM-2006-FORM 18(27-4-2009).pdf | 2018-08-09 |
| 29 | 321-MUM-2006-CORRESPONDENCE(9-6-2015).pdf | 2018-08-09 |
| 29 | 321-MUM-2006-FORM 2(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 30 | 321-MUM-2006-CORRESPONDENCE(31-3-2016).pdf | 2018-08-09 |
| 30 | 321-MUM-2006-FORM 2(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 31 | 321-MUM-2006-CORRESPONDENCE(28-4-2015).pdf | 2018-08-09 |
| 31 | 321-MUM-2006-FORM 2(TITLE PAGE)-(28-4-2015).pdf | 2018-08-09 |
| 32 | 321-MUM-2006-CORRESPONDENCE(27-2-2007).pdf | 2018-08-09 |
| 32 | 321-MUM-2006-FORM 2(TITLE PAGE)-(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 33 | 321-MUM-2006-CORRESPONDENCE(13-5-2009).pdf | 2018-08-09 |
| 33 | 321-MUM-2006-FORM 2(TITLE PAGE)-(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 34 | 321-MUM-2006-CLAIMS(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 34 | 321-MUM-2006-FORM 3(27-2-2007).pdf | 2018-08-09 |
| 35 | 321-MUM-2006-CLAIMS(COMPLETE)-(27-2-2007).pdf | 2018-08-09 |
| 35 | 321-MUM-2006-FORM 3(7-3-2006).pdf | 2018-08-09 |
| 36 | 321-MUM-2006-FORM 5(27-2-2007).pdf | 2018-08-09 |
| 36 | 321-MUM-2006-CLAIMS(AMENDED)-(9-6-2015).pdf | 2018-08-09 |
| 37 | 321-MUM-2006-CLAIMS(AMENDED)-(28-4-2015).pdf | 2018-08-09 |
| 37 | 321-MUM-2006-FORM 5(3-8-2006).pdf | 2018-08-09 |
| 38 | 321-MUM-2006-CLAIMS(AMENDED)-(16-1-2013).pdf | 2018-08-09 |
| 38 | 321-MUM-2006-GENERAL POWER OF ATTORNEY(28-4-2015).pdf | 2018-08-09 |
| 39 | 321-MUM-2006-ABSTRACT(PROVISIONAL)-(7-3-2006).pdf | 2018-08-09 |
| 39 | 321-MUM-2006-MARKED COPY(28-4-2015).pdf | 2018-08-09 |
| 40 | 321-MUM-2006-ABSTRACT(27-2-2007).pdf | 2018-08-09 |
| 40 | 321-MUM-2006-PETITION UNDER RULE-137(28-4-2015).pdf | 2018-08-09 |
| 41 | 321-MUM-2006-RELEVANT DOCUMENTS [14-03-2019(online)].pdf | 2019-03-14 |
| 41 | 321-MUM-2006-REPLY TO EXAMINATION REPORT(16-1-2013).pdf | 2018-08-09 |
| 42 | 321-MUM-2006-REPLY TO HEARING(28-4-2015).pdf | 2018-08-09 |
| 42 | 321-MUM-2006-RELEVANT DOCUMENTS [11-03-2020(online)].pdf | 2020-03-11 |
| 43 | 321-MUM-2006-SPECIFICATION(AMENDED)-(28-4-2015).pdf | 2018-08-09 |
| 43 | 321-MUM-2006-RELEVANT DOCUMENTS [30-03-2021(online)].pdf | 2021-03-30 |
| 44 | 321-MUM-2006_EXAMREPORT.pdf | 2018-08-09 |
| 44 | 321-MUM-2006-RELEVANT DOCUMENTS [30-03-2022(online)].pdf | 2022-03-30 |
| 45 | 321-MUM-2006-RELEVANT DOCUMENTS [29-03-2023(online)].pdf | 2023-03-29 |
| 45 | 321-MUM-2006-RELEVANT DOCUMENTS [23-02-2018(online)].pdf | 2018-02-23 |
| 46 | 321-MUM-2006-RELEVANT DOCUMENTS [19-03-2024(online)].pdf | 2024-03-19 |
| 46 | 321-MUM-2006-CORRESPONDENCE(RENEWAL PAYMENT LETTER)-(07-04-2016).pdf | 2016-04-07 |