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Pyrazine Carboxamide Compound
Abstract: [Problem] To provide a compound that is useful as an inhibitor of EGFR T790M mutation kinase activity. [Solution] The inventors studied compounds having an inhibiting effect against EGFR T790M mutation kinase and perfected the invention upon confirming that a pyrazine carboxamide compound has an inhibiting effect against EGFR T790M mutation kinase. The pyrazine carboxamide compound of the invention has an inhibiting effect against the EGFR T790M mutation kinase and can be used as a prophylactic and/or therapeutic agent for EGFR T790M mutation positive cancer EGFR T790M mutation positive lung cancer EGFR T790M mutation positive non small cell lung cancer EGFR T790M mutation protein positive cancer and EGFR T90M mutation protein positive lung cancer.
Notices, Deadlines & Correspondence
Patent Information
Applicants
ASTELLAS PHARMA INC.
Inventors
1. MATSUYA Takahiro
2. KONDOH Yutaka
3. SHIMADA Itsuro
4. KIKUCHI Shigetoshi
5. IIDA Maiko
6. ONDA Kenichi
7. FUKUDOME Hiroki
8. TAKEMOTO Yukihiro
9. SHINDOU Nobuaki
10. SAKAGAMI Hideki
11. HAMAGUCHI Hisao
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 5380-CHENP-2014-AbandonedLetter.pdf | 2019-01-23 |
| 1 | OTHERS.pdf | 2014-07-23 |
| 2 | GENERAL POWER OF ATTORNEY.pdf | 2014-07-23 |
| 2 | 5380-CHENP-2014-FER.pdf | 2018-07-19 |
| 3 | FORM-5.pdf | 2014-07-23 |
| 3 | 5380-CHENP-2014-Correspondence-030316.pdf | 2016-07-01 |
| 4 | 5380-CHENP-2014-Correspondence-161015.pdf | 2016-03-23 |
| 4 | FORM-3.pdf | 2014-07-23 |
| 5 | COMPLETE SPECIFICATION.pdf | 2014-07-23 |
| 5 | 5380-CHENP-2014-Form 3-161015..pdf | 2016-03-23 |
| 6 | 5380-CHENP-2014.pdf | 2014-07-25 |
| 6 | 5380-CHENP-2014 CORRESPONDENCE OTHERS 06-01-2015.pdf | 2015-01-06 |
| 7 | 5380-CHENP-2014 FORM-3 06-01-2015.pdf | 2015-01-06 |
| 7 | 5380-CHENP-2014 FORM-1 06-01-2015.pdf | 2015-01-06 |
| 8 | 5380-CHENP-2014 FORM-3 06-01-2015.pdf | 2015-01-06 |
| 8 | 5380-CHENP-2014 FORM-1 06-01-2015.pdf | 2015-01-06 |
| 9 | 5380-CHENP-2014.pdf | 2014-07-25 |
| 9 | 5380-CHENP-2014 CORRESPONDENCE OTHERS 06-01-2015.pdf | 2015-01-06 |
| 10 | 5380-CHENP-2014-Form 3-161015..pdf | 2016-03-23 |
| 10 | COMPLETE SPECIFICATION.pdf | 2014-07-23 |
| 11 | 5380-CHENP-2014-Correspondence-161015.pdf | 2016-03-23 |
| 11 | FORM-3.pdf | 2014-07-23 |
| 12 | FORM-5.pdf | 2014-07-23 |
| 12 | 5380-CHENP-2014-Correspondence-030316.pdf | 2016-07-01 |
| 13 | GENERAL POWER OF ATTORNEY.pdf | 2014-07-23 |
| 13 | 5380-CHENP-2014-FER.pdf | 2018-07-19 |
| 14 | OTHERS.pdf | 2014-07-23 |
| 14 | 5380-CHENP-2014-AbandonedLetter.pdf | 2019-01-23 |
Search Strategy
| 1 | Searchstrategy_5380chenp2014_17-07-2018.pdf |