Saccharin Derivatives As Orally Active Elastase Inhibtors

Abstract: Compounds of he general formula (I) wherein R1 is methyl, ethyl or 2-morpholino-ehtyl-group; R2 is piperidino, moorpholino or 4-methyl-piperazinyl group; n is 2 or 3- and their salts, solvates and hydrates.

Patent Information

Application #

Filing Date

28 May 2002

Publication Number

09/2004

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

SANOFI-SYNTHELABO

174, AVENUE DE FRANCE, F-75013 PARIS.

Inventors

1. PETER ARANYI

BIMBO U. 261/226, H-1026 BUDAPEST.

2. SANDOR BATORI

RAKOCZI F.U. 268/A, H-1214 BUDAPEST II.

3. STEPHANE DESSILLA

600 AVNUE PAUL DEMARNE, F-34800 CANET.

4. ISTVAN HERMECZ

RADAR U. 32, H-1092 BUDAPEST.

5. FERRENC LEVAI

CHAZAR A. U. 19, H-1146 BUDAPEST.

6. ZOLTAN KAPUI

ETLE U. 56/A, H-1115 BUTAPEST.

7. ENDRE MIKUS.

IDA U. 96, H-1162 BUTAPEST.

8. MARC PASCAL.

LA MUGUETTE, CHEMIN DE MONTAURIOL, F-31280 DERMIL-LAFAGE.

9. LAJOS T. NAGY

ISTVAN U. 47, H-1078 BUDAPEST.

10. BROUNO SIMONOT

ENTREE 4,342, RUE DES ESCARCELIERS, F34080 MONTPELLIER.

11. KATALIN URBAN SZABO

SZT. LASZLO U. 158. H-1131 BUDAPEST.

12. MARTON VARGA.

BARASTSAG U. 9, H-2120 DUNAKESZI.

13. VASVARINE DEBRECZY.

GLDMARK K. U 33, H-1122 BUDAPEST.