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Small Molecule Urea Derivatives As Sting Antagonists
Abstract: The present invention relates to compounds of formula (I). The compounds maybe used to antagonise the Stimulator of Interferon Genes (STING) protein and may thereby treat liver fibrosis, fatty liver disease, non-alcoholic steatohepatitis (NASH), pulmonary fibrosis, lupus, sepsis, rheumatoid arthritis (RA), type I diabetes, STING-associated vasculopathy with onset in infancy (SAVI), Aicardi-Goutieres syndrome (AGS), familial chilblain lupus (FCL), systemic lupus erythematosus (SLE), retinal vasculopathy, neuroinflammation, systemic inflammatory response syndrome, pancreatitis, cardiovascular disease, renal fibrosis, stroke and age- related macular degeneration (AMD).
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
02 February 2024
Publication Number
08/2024
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Applicants
CURADEV PHARMA PVT. LTD.
Plot No. B-87, Sector 83
Noida
Uttar Pradesh 201305
Inventors
1. BANERJEE, Monali
c/o Curadev Pharma Pvt. Ltd. Plot No. B-87, Sector 83 Noida
Uttar Pradesh 201305
2. BASU, Sourav
c/o Curadev Pharma Pvt. Ltd. Plot No. B-87, Sector 83 Noida
Uttar Pradesh 201305
3. SHRIVASTAVA, Ritesh Kumar
c/o Curadev Pharma Pvt. Ltd. Plot No. B-87, Sector 83 Noida
Uttar Pradesh 201305
4. PRYDE, David Cameron
c/o Curadev Pharma Ltd. Innovation House Discovery Park
Sandwich Kent CT13 9ND
5. MIDDYA, Sandip Kumar
c/o Curadev Pharma Pvt. Ltd. Plot No. B-87, Sector 83 Noida
Uttar Pradesh 201305
6. GHOSH, Rajib
c/o Curadev Pharma Pvt. Ltd. Plot No. B-87, Sector 83 Noida
Uttar Pradesh 201305
7. YADAV, Dharmendra B.
c/o Curadev Pharma Pvt. Ltd. Plot No. B-87, Sector 83 Noida
Uttar Pradesh 201305
8. SURYA, Arjun
c/o Curadev Pharma Pvt. Ltd. Plot No. B-87, Sector 83 Noida
Uttar Pradesh 201305
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202417007176-STATEMENT OF UNDERTAKING (FORM 3) [02-02-2024(online)].pdf | 2024-02-02 |
| 2 | 202417007176-PRIORITY DOCUMENTS [02-02-2024(online)].pdf | 2024-02-02 |
| 3 | 202417007176-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [02-02-2024(online)].pdf | 2024-02-02 |
| 4 | 202417007176-FORM 1 [02-02-2024(online)].pdf | 2024-02-02 |
| 5 | 202417007176-DECLARATION OF INVENTORSHIP (FORM 5) [02-02-2024(online)].pdf | 2024-02-02 |
| 6 | 202417007176-COMPLETE SPECIFICATION [02-02-2024(online)].pdf | 2024-02-02 |
| 7 | 202417007176-FORM-26 [18-03-2024(online)].pdf | 2024-03-18 |
| 8 | 202417007176-Proof of Right [26-03-2024(online)].pdf | 2024-03-26 |
| 9 | 202417007176-GPA-260324.pdf | 2024-04-15 |
| 10 | 202417007176-Correspondence-260324.pdf | 2024-04-15 |
| 11 | 202417007176-Others-280324.pdf | 2024-04-18 |
| 12 | 202417007176-Correspondence-280324.pdf | 2024-04-18 |
| 13 | 202417007176-FORM 3 [01-08-2024(online)].pdf | 2024-08-01 |
| 14 | 202417007176-RELEVANT DOCUMENTS [05-06-2025(online)].pdf | 2025-06-05 |
| 15 | 202417007176-MARKED COPIES OF AMENDEMENTS [05-06-2025(online)].pdf | 2025-06-05 |
| 16 | 202417007176-FORM 13 [05-06-2025(online)].pdf | 2025-06-05 |
| 17 | 202417007176-AMMENDED DOCUMENTS [05-06-2025(online)].pdf | 2025-06-05 |
| 18 | 202417007176-FORM 18 [06-06-2025(online)].pdf | 2025-06-06 |