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Solid Pharmaceutical Dosage Form
Abstract: A solid pharmaceutical dosage form providing improved oral bioavailability is disclosed for inhibitors of HIV protease. In particular, the dosage form comprises a solid dispersion of at least one HIV protease inhibitor and at least one pharmaceutically acceptable water-soluble polymer and at least one pharmaceutically acceptable surfactant, said pharmaceutically acceptable water-soluble polymer having a Tg of at least about 50 °C. Preferably, the pharmaceutically acceptable surfactant has an HLB value of from about 4 to about 10.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
15 April 2009
Publication Number
21/2009
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
Parent Application
Applicants
Abbott Laboratories
Dept. 377 Bldg AP6A-1 100 Abbott Park Road Abbott Park IL 60064-6008 USA.
Inventors
1. ROSENBERG Jöerg
Bruchstrasse 29 67158 Ellerstadt Germany.
2. REINHOLD Ulrich
Hilgardstrasse 18 67346 Speyer Germany.
3. LIEPOLD Bernd
U1 8; Mannheim 68161 Mannheim Germany.
4. DERNDL Gunther
Am Dörrling 7 67273 Herxheim Germany.
5. BREITENBACH Jörg
Hans Sachs Ring 95a 68199 Mannheim Germany.
6. ALANI Laman
4612 Merchant Square Lansdale PA 19446 USA.
7. GHOSH Soumojeet
48826 Central Park Drive Canton MI 48188 USA.
Specification
attached
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 726-MUMNP-2009- FORM 18 (29-05-2009).pdf | 2009-05-29 |
| 1 | 726-MUMNP-2009-ABSTRACT(29-5-2009).pdf | 2018-08-10 |
| 2 | 726-MUMNP-2009- CORRESPONDENCE (03-12-2009).pdf | 2009-12-03 |
| 2 | 726-MUMNP-2009-ASSIGNMENT(29-5-2009).pdf | 2018-08-10 |
| 3 | 726-MUMNP-2009-CORRESPONDENCE(28-11-2011).pdf | 2011-11-28 |
| 3 | 726-MUMNP-2009-CLAIMS(29-5-2009).pdf | 2018-08-10 |
| 4 | 726-MUMNP-2009-CORRESPONDENCE(15-10-2012).pdf | 2012-10-15 |
| 4 | 726-MUMNP-2009-CLAIMS(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 5 | 726-MUMNP-2009-CORRESPONDENCE(IPO)-(16-10-2012).pdf | 2012-10-16 |
| 5 | 726-MUMNP-2009-CORRESPONDENCE(14-1-2010).pdf | 2018-08-10 |
| 6 | 726-MUMNP-2009-CORRESPONDENCE(29-10-2012).pdf | 2012-10-29 |
| 6 | 726-MUMNP-2009-CORRESPONDENCE(16-9-2011).pdf | 2018-08-10 |
| 7 | Priority Document.pdf | 2018-08-10 |
| 7 | 726-MUMNP-2009-CORRESPONDENCE(2-2-2011).pdf | 2018-08-10 |
| 8 | Form-5.pdf | 2018-08-10 |
| 8 | 726-MUMNP-2009-CORRESPONDENCE(29-5-2009).pdf | 2018-08-10 |
| 9 | 726-MUMNP-2009-CORRESPONDENCE(30-6-2009).pdf | 2018-08-10 |
| 9 | Form-3.pdf | 2018-08-10 |
| 10 | 726-MUMNP-2009-CORRESPONDENCE(5-3-2012).pdf | 2018-08-10 |
| 10 | Form-1.pdf | 2018-08-10 |
| 11 | 726-MUMNP-2009-CORRESPONDENCE(6-10-2009).pdf | 2018-08-10 |
| 11 | 726-MUMNP-2009_EXAMREPORT.pdf | 2018-08-10 |
| 12 | 726-MUMNP-2009-DESCRIPTION(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 12 | 726-MUMNP-2009-WO INTERNATIONAL PUBLICATION REPORT A3(29-5-2009).pdf | 2018-08-10 |
| 13 | 726-MUMNP-2009-DESCRIPTION(COMPLETE)-(29-5-2009).pdf | 2018-08-10 |
| 13 | 726-MUMNP-2009-WO INTERNATIONAL PUBLICATION REPORT A2(29-5-2009).pdf | 2018-08-10 |
| 14 | 726-MUMNP-2009-FORM 1(29-5-2009).pdf | 2018-08-10 |
| 14 | 726-MUMNP-2009-RECEIPT(IPO)-(29-5-2009).pdf | 2018-08-10 |
| 15 | 726-MUMNP-2009-FORM 18(6-10-2009).pdf | 2018-08-10 |
| 15 | 726-mumnp-2009-pregrant opposition(5-8-2010).pdf | 2018-08-10 |
| 16 | 726-mumnp-2009-form 2(29-5-2009).pdf | 2018-08-10 |
| 16 | 726-MUMNP-2009-PRE-GRANT OPPOSITION LETTER(1-3-2011).pdf | 2018-08-10 |
| 17 | 726-MUMNP-2009-PCT-RO-111(29-5-2009).pdf | 2018-08-10 |
| 17 | 726-MUMNP-2009-FORM 2(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 18 | 726-MUMNP-2009-FORM 2(TITLE PAGE)-(29-5-2009).pdf | 2018-08-10 |
| 18 | 726-MUMNP-2009-PCT-ISA-210(29-5-2009).pdf | 2018-08-10 |
| 19 | 726-MUMNP-2009-FORM 2(TITLE PAGE)-(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 19 | 726-MUMNP-2009-PCT-IB-304(29-5-2009).pdf | 2018-08-10 |
| 20 | 726-MUMNP-2009-FORM 3(29-5-2009).pdf | 2018-08-10 |
| 20 | 726-MUMNP-2009-PCT REQUEST(29-5-2009).pdf | 2018-08-10 |
| 21 | 726-MUMNP-2009-FORM 5(29-5-2009).pdf | 2018-08-10 |
| 21 | 726-MUMNP-2009-OTHER DOCUMENT(29-5-2009).pdf | 2018-08-10 |
| 22 | 726-MUMNP-2009-FORM 5(29-5-2009).pdf | 2018-08-10 |
| 22 | 726-MUMNP-2009-OTHER DOCUMENT(29-5-2009).pdf | 2018-08-10 |
| 23 | 726-MUMNP-2009-FORM 3(29-5-2009).pdf | 2018-08-10 |
| 23 | 726-MUMNP-2009-PCT REQUEST(29-5-2009).pdf | 2018-08-10 |
| 24 | 726-MUMNP-2009-PCT-IB-304(29-5-2009).pdf | 2018-08-10 |
| 24 | 726-MUMNP-2009-FORM 2(TITLE PAGE)-(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 25 | 726-MUMNP-2009-FORM 2(TITLE PAGE)-(29-5-2009).pdf | 2018-08-10 |
| 25 | 726-MUMNP-2009-PCT-ISA-210(29-5-2009).pdf | 2018-08-10 |
| 26 | 726-MUMNP-2009-FORM 2(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 26 | 726-MUMNP-2009-PCT-RO-111(29-5-2009).pdf | 2018-08-10 |
| 27 | 726-mumnp-2009-form 2(29-5-2009).pdf | 2018-08-10 |
| 27 | 726-MUMNP-2009-PRE-GRANT OPPOSITION LETTER(1-3-2011).pdf | 2018-08-10 |
| 28 | 726-MUMNP-2009-FORM 18(6-10-2009).pdf | 2018-08-10 |
| 28 | 726-mumnp-2009-pregrant opposition(5-8-2010).pdf | 2018-08-10 |
| 29 | 726-MUMNP-2009-FORM 1(29-5-2009).pdf | 2018-08-10 |
| 29 | 726-MUMNP-2009-RECEIPT(IPO)-(29-5-2009).pdf | 2018-08-10 |
| 30 | 726-MUMNP-2009-DESCRIPTION(COMPLETE)-(29-5-2009).pdf | 2018-08-10 |
| 30 | 726-MUMNP-2009-WO INTERNATIONAL PUBLICATION REPORT A2(29-5-2009).pdf | 2018-08-10 |
| 31 | 726-MUMNP-2009-DESCRIPTION(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 31 | 726-MUMNP-2009-WO INTERNATIONAL PUBLICATION REPORT A3(29-5-2009).pdf | 2018-08-10 |
| 32 | 726-MUMNP-2009-CORRESPONDENCE(6-10-2009).pdf | 2018-08-10 |
| 32 | 726-MUMNP-2009_EXAMREPORT.pdf | 2018-08-10 |
| 33 | 726-MUMNP-2009-CORRESPONDENCE(5-3-2012).pdf | 2018-08-10 |
| 33 | Form-1.pdf | 2018-08-10 |
| 34 | 726-MUMNP-2009-CORRESPONDENCE(30-6-2009).pdf | 2018-08-10 |
| 34 | Form-3.pdf | 2018-08-10 |
| 35 | 726-MUMNP-2009-CORRESPONDENCE(29-5-2009).pdf | 2018-08-10 |
| 35 | Form-5.pdf | 2018-08-10 |
| 36 | Priority Document.pdf | 2018-08-10 |
| 36 | 726-MUMNP-2009-CORRESPONDENCE(2-2-2011).pdf | 2018-08-10 |
| 37 | 726-MUMNP-2009-CORRESPONDENCE(29-10-2012).pdf | 2012-10-29 |
| 37 | 726-MUMNP-2009-CORRESPONDENCE(16-9-2011).pdf | 2018-08-10 |
| 38 | 726-MUMNP-2009-CORRESPONDENCE(IPO)-(16-10-2012).pdf | 2012-10-16 |
| 38 | 726-MUMNP-2009-CORRESPONDENCE(14-1-2010).pdf | 2018-08-10 |
| 39 | 726-MUMNP-2009-CORRESPONDENCE(15-10-2012).pdf | 2012-10-15 |
| 39 | 726-MUMNP-2009-CLAIMS(COMPLETE)-(15-4-2009).pdf | 2018-08-10 |
| 40 | 726-MUMNP-2009-CORRESPONDENCE(28-11-2011).pdf | 2011-11-28 |
| 40 | 726-MUMNP-2009-CLAIMS(29-5-2009).pdf | 2018-08-10 |
| 41 | 726-MUMNP-2009-ASSIGNMENT(29-5-2009).pdf | 2018-08-10 |
| 41 | 726-MUMNP-2009- CORRESPONDENCE (03-12-2009).pdf | 2009-12-03 |
| 42 | 726-MUMNP-2009- FORM 18 (29-05-2009).pdf | 2009-05-29 |
| 42 | 726-MUMNP-2009-ABSTRACT(29-5-2009).pdf | 2018-08-10 |