Stabilized Nitroglycerin Fast Dissolving Tablet Preparation And

Stabilized Nitroglycerin Fast Dissolving Tablet Preparation And Process For Preparation Thereof

Abstract: The present invention relates to the preparation of a novel, stable and fast dissolving sub lingual tablets of Nitroglycerin. The oral dosage form of nitroglycerin of the invention can be administered sublingually to treat episodes of angina (chest pain) or just before activities that may cause episodes of angina in order to prevent angina pectoris. The invention preparation is characterized by low degradation profile, maintenance of potency with minimum vaporization of Active Pharmaceutical Ingredient (API) and no migration of nitroglycerin from one dosage unit to another dosage unit or to container or to container components, resulting in excellent stability and better content uniformity on storage in unit-dose or multi-dose containers.

Patent Information

Application #

Filing Date

16 November 2022

Publication Number

20/2024

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

Modi-Mundipharma Pvt. Ltd.

1400, Modi Tower, 98 Nehru Place, New Delhi- 110019, India

Inventors

1. Balkrishan Bansal

c/o Modi- Mundipharma Research & Development Centre, Modipuram, Meerut, Uttar Pradesh, India

2. Vishal Gupta

c/o Modi- Mundipharma Research & Development Centre, Modipuram, Meerut, Uttar Pradesh, India

3. Rajesh Agrawal

c/o Modi- Mundipharma Research & Development Centre, Modipuram, Meerut, Uttar Pradesh, India

4. Mithu Sen

c/o Modi- Mundipharma Research & Development Centre, Modipuram, Meerut, Uttar Pradesh, India

Specification

DESC:Attached ,CLAIMS:Attached

Documents

Application Documents

#	Name	Date
1	202211065737-STATEMENT OF UNDERTAKING (FORM 3) [16-11-2022(online)].pdf	2022-11-16
2	202211065737-PROVISIONAL SPECIFICATION [16-11-2022(online)].pdf	2022-11-16
3	202211065737-FORM 1 [16-11-2022(online)].pdf	2022-11-16
4	202211065737-Proof of Right [13-12-2022(online)].pdf	2022-12-13
5	202211065737-FORM-26 [20-12-2022(online)].pdf	2022-12-20
6	202211065737-Others-231222.pdf	2022-12-26
7	202211065737-GPA-231222.pdf	2022-12-26
8	202211065737-Correspondence-231222.pdf	2022-12-26
9	202211065737-Correspondence-231222-1.pdf	2022-12-26
10	202211065737-CORRESPONDENCE-OTHERS [16-11-2023(online)].pdf	2023-11-16
11	202211065737-COMPLETE SPECIFICATION [16-11-2023(online)].pdf	2023-11-16
12	202211065737-Request Letter-Correspondence [23-02-2024(online)].pdf	2024-02-23
13	202211065737-Form 1 (Submitted on date of filing) [23-02-2024(online)].pdf	2024-02-23
14	202211065737-Covering Letter [23-02-2024(online)].pdf	2024-02-23