Description:STABLE AGROCHEMICAL COMPOSITION

FIELD OF THE INVENTION:

The present invention is to provide stabilized agrochemical composition with non-hazardous solvents. In a particular aspect of present invention relates to an emulsion composition comprises of an organo-phosphorus active ingredient or its combination with a pyrethroid active ingredient, surfactant, stabilizer, aqueous medium, optionally one or more green oil or auxiliary agent.

BACKGROUND OF THE INVENTION:

Pests can have an adverse and damaging impact on agricultural production by affecting crops production. Also, pests have a detrimental effect on the environment and human health. To control pests, several organo-phosphorous or pyrethroid pesticides have been developed and are currently in use e.g. profenofos, ethion, or cypermethrin. However, such insecticides need a suitable insecticidal formulation to be used for the treatment of pests of crop plant without causing any harm to the respective environment.

Organo-phosphorus active ingredients are esters of phosphoric acid. Profenofos (shown in Figure 1), and ethion represent a class of organo-phosphorus broad-spectrum insecticides known for its high efficacy, systemic absorption and low residue.

Profenofos is an acetyl cholinesterase inhibitor that produces contact and stomach toxicity in the pests. It is chemically known as 4-bromo-2-chloro-1-[ethoxy(propylsulfanyl)phosphoryl] oxybenzene and was first described in U.S. patent 3,992,533, which is assigned to Ciba-Geigy Corporation. It is used for the treatment of the pests on a variety of crops namely cotton, tea, tobacco, maize, potato, soybean, sugar beet and vegetables. It is used mainly on the cotton crop plant against aphids, jassids or lepidopteran pests. It is effective against organo-phosphorous and pyrethroid-resistant cotton pests. It has the following structure:

Pyrethroid active ingredients are synthetic derivatives of pyrethrins. Pyrethroid active ingredients have been found to give excellent control of pests of the order of Lepidoptera. Cypermethrin represents a class of pyrethroid insecticides.

Pesticidal emulsion formulation is used worldwide as they are simple to handle and convenient to dispense in the field, mainly as a spray with water. U.S. patent application 20020098221 discloses the general method of preparation of oil in water emulsion of pyrethroid insecticides. Chinese patent application 102326580 discloses profenofos emulsion in water which comprises of profenofos, surfactant, water and co-solvent as toluene and xylene. Chinese patent 101606517 discloses an aqueous pesticidal emulsion formulation of profenofos that contains α-pinene, D-limonene and jatropha oil methyl ester as a solvent.

Organo-phosphorus active ingredient such as profenofos and ethion; pyrethroid active ingredient such as cypermethrin are available as an emulsifiable concentrate (EC) formulation.

In general, organo-phosphorus active ingredient based pesticide has very low water solubility and low half-life in water (DT50). In most of the cases these DT50 values are sensitive to pH. Organo-phosphorus active ingredients tend to have lowest DT50 values at pH ≥ 7.

Under these circumstances with low DT50 value, developing aqueous based formulation with shelf-life ≤ 2 years is challenging as activity of organo-phosphorus active ingredients decrease rapidly.

Active Ingredient Water Solubility
(mg /l) DT50
pH = 5 pH = 7 pH = 9
Profenofos 28 93 Days 14.6 Days 5.-7 hours
Ethion 2 390 Days
Chlorpyrifos (CPS) 1.4 1.5 Days (pH =8) 1.5 Days
Chlorethoxyfos 1 4.3 Days 59 Days 72 Days

The need of making aqueous based formulation arises from the fact that in the conventional EC formulations large amount of hydrocarbons, which are atmospheric contaminants and are carcinogenic to birds and mammals. Low biodegradability makes them unfavorable in context to safety and sustainability of the environment and earth.
Because of the degradation issues, it is technically essential to develop technologies and identify suitable stabilizers to prevent such degradation in organo-phosphorus active ingredients.

Inventors of present invention surprisingly found that urea and its derivative; several amines can prevent such degradation of organo-phosphorus active ingredients.

Moreover, the solvents conventionally used in such EC formulation are mainly aromatic hydrocarbons namely toluene and xylene. Such solvents are known to adversely impact the environment and hence fail to meet the requirements and trends of sustainable agricultural practices. Use of organic solvents is known to be a health hazard as these solvents are known to be carcinogenic and toxic to mammals including humans.

The object of the present invention is to provide stabilized agrochemical composition with non-hazardous solvents such as aqueous formulation, which is safe and free from hazardous volatile organic solvents like toluene and/or xylene, is effective in controlling pests, and which has advantageous properties that overcome the above mentioned shortcoming.

SUMMARY OF THE INVENTION

In one aspect, the present invention relates to a method of stabilizing an agrochemical composition comprising of:
addition of one or more agrochemical active ingredient;
addition of one or more stabilizer;
optionally addition of one or more surfactant;
optionally addition of an aqueous medium;
optionally addition of one or more green oil or auxiliary agent;
wherein the stabilizer is selected from the group comprising of urea or its derivatives , triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In a further aspect, the present invention relates to an emulsion composition comprising:
one or more organo-phosphorus active ingredient,
one or more surfactant,
one or more stabilizer,
an aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In another aspect, the present invention relates to an emulsion composition comprising:
one or more active ingredient in combination is selected from the group comprising of organo-phosphorus and pyrethroid,
one or more surfactant,
one or more stabilizer,
an aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In a further aspect, the present invention relates to an emulsion composition comprising:
active ingredient profenofos or ethion or a combination thereof,
one or more surfactant,
one or more stabilizer,
an aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In another aspect, the present invention relates to an emulsion composition comprising:
profenofos or ethion in combination with cypermethrin or its derivatives thereof,
one or more surfactant,
one or more stabilizer,
an aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In an aspect of the present invention, the median particle size of the emulsified composition is about 0.1 µm to about 5 µm, preferably about 1 μm.

In a further aspect, the present invention relates to a process for preparing an emulsion composition comprising the steps of:
Preparation of an oil phase comprising the steps of:
addition of one or more organo-phosphorus active ingredient,
addition of one or more surfactant,
optionally one or more green oil to obtain the oil phase,
Preparation of an aqueous phase comprising the steps of:
addition of one or more surfactant in an aqueous medium,
addition of one or more stabilizer,
optionally one or more auxiliary agent,
mixing the oil phase into the aqueous phase or vice-versa to obtain the emulsion composition.

In a further aspect, the present invention relates to a process for preparing an emulsion composition comprising the steps of:
Preparation of an oil phase comprising the steps of:
addition of one or more active ingredient selected from organo-phosphorus and pyrethroid,
addition of one or more surfactant,
optionally one or more green oil to obtain the oil phase,
Preparation of an aqueous phase comprising the steps of:
addition of one or more surfactant in an aqueous medium,
addition of one or more stabilizer,
optionally one or more auxiliary agent,
mixing the oil phase into the aqueous phase or vice-versa to obtain the emulsion composition.

The above mentioned steps for preparing the emulsion composition may be modified by a person skilled in the art.

In a further aspect of the present invention, the emulsion composition comprises of an aqueous phase and an oil phase; the surfactant in both phases has different hydrophilic-lipophilic balance (HLB) value, wherein the surfactant in oil phase has HLB value between 4 and 12 and the surfactant in aqueous phase has balance has HLB value between 12 and 20.
The emulsion composition according to the present invention is used to control pests in crops such as, but not limited to, cotton, tea, tobacco, potatoes, soybean, maize, capsicum, rice and other vegetable crops and offers the following advantages:
offers high storage stability.
use of environmentally friendly solvents in the preparation of the formulation as compared to toluene and/or xylene, which adversely impact the environment as well as mammals including humans.
offers higher biological activity.

Accordingly, it is an objective and advantage of the present invention to provide an environmentally safe and effective emulsion composition of one or more organo-phosphorus active ingredient or its combination with pyrethroid active ingredient that is effective against pests of cotton, tobacco, tea and vegetable crops such as potatoes.

Another objective and advantage of the present invention is to provide an emulsion composition that shows technical advancement compared to existing emulsion concentrate formulation of an organo-phosphorus or its combination with pyrethroid active ingredient.

Another objective and advantage of the present invention is to provide a composition which meets environmental and economic requirements imposed on modern-day insecticides which are continually increasing for example, about application rate, the formation of residues, low costs, and favorable preparation ability.

The above and other objectives will become more apparent in view of the description given below.

DETAILED DESCRIPTION OF THE INVENTION:

DEFINITIONS

It will be understood that the terminology used herein is to describe embodiments only, and is not intended to be limiting. As used in this specification, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, the reference to "a surfactant" includes one or more such surfactants.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention pertains. Although other methods and materials similar, or equivalent, to those described herein can be used in the practice of the present invention, the preferred materials and methods are described herein.

As used herein, the terms "comprises", "comprising", "includes", "including", or any other variation thereof, are intended to cover a non-exclusive inclusion, subject to any limitation explicitly indicated. For example, a composition or a method that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, or method.

As used herein, the term “composition” or "formulation" can be used interchangeably, unless stated otherwise, is meant to encompass, and are not limited to, compositions or formulations containing one or more organo-phosphorus active ingredient or its combination with pyrethroid active ingredient.

As used herein, the term “green oil” refers to the oils which are natural in origin or obtained from a plant source or cause less harm to the environment.

As used herein, the term "auxiliary agent" refers to inert substances which are commonly used as the diluent, to provide stability or to increase the activity profile of the formulation with or without having agrochemical activity or direct effect on the pests.

As used herein, the term “aqueous medium” refers to any polar solvent selected from water, ethanol, methanol, n-butanol, isopropanol, n-propanol, or formic acid, preferably the aqueous medium is water.

As used herein, the term “surfactant(s)” means a compound that, when dissolved in a liquid, reduces the surface tension of the liquid, which reduces the interfacial tension between two liquids or which reduces surface tension between a liquid and a solid. More typically the term “surfactant” is used herein to refer to a compound that, when dissolved in oil/water, reduces the surface tension of the oil/water.

As used herein, the term “stabilizer(s)” refers to a substance capable of imparting resistance against physical or chemical deterioration or deformulation.

As used herein, the term “defoamer agent(s)” refers to a chemical additive that reduces and hinders the formation of foam in the industrial process of liquids, semi-solids, or solids. The terms defoamer and anti-foaming agent are used interchangeably.

As used herein, the term “thickener(s)” refers to a polymeric material, which at a low concentration increases the viscosity of an aqueous solution and helps to stabilize the emulsion.

Unless otherwise specified, % refers to % weight; and % weight refers to % of the weight of respective component with respect to the total weight of the composition. For the present invention, the term “about” refers to ±1% to 10% of a specified value.

As used herein, the term “profenofos” encompasses profenofos or its salt, derivatives or any other modified form of profenofos.

As used herein, the term “ethion” encompasses ethion or its salt, derivatives or any other modified form of ethion.

As used herein, the term “cypermethrin” encompasses cypermethrin or its salt, derivatives or any other modified form of cypermethrin like alpha-cypermethrin, beta-cypermethrin, deltamethrin, theta-cypermethrin or zeta-cypermethrin.

Accordingly, the present invention relates to an emulsion composition of one or more organo-phosphorus active ingredient (such as profenofos or ethion) or its combination with pyrethroid active ingredient (such as cypermethrin) to provide a fast-acting, safer-to-use, environmentally friendly formulation.

An emulsion is a conventional formulation in the field of the agrochemical formulations. The emulsion is pre-formed in the commercial product and is conventionally diluted with a carrier (usually water) when making up the spray mixture. They, therefore, differ from emulsifiable concentrates which comprise pesticides in an anhydrous formulation in organic solvents. Emulsifiable concentrates formulations form an emulsion only when making up the spray mixture. The disadvantage of emulsifiable concentrates formulation is the high content of organic solvents.

The emulsion composition according to the invention comprises of a continuous water phase and a dispersed oil phase. The mass median diameter of oil droplet size is usually in the range of about 0.1 to about 5 μm. The median particle size of the emulsified composition is about 0.1 µm to about 5 µm, preferably about 1 μm. The mass median diameter can be determined by particle-size measurement by laser diffraction, for example using a Malvern Mastersizer 2000.

In an embodiment of the present invention, the emulsion comprises of one or more organo-phosphorus active ingredient (such as profenofos, or ethion) or its composition with pyrethroid active ingredient (such as cypermethrin) as an active substance, dispersed in the water phase in the amount about 1% to 75% by weight, preferably about 2% to 65% by weight, and more preferably about 5% to 60% by weight.

In a preferred embodiment of the present invention, the emulsion composition according to the present invention further comprises of urea or its derivative as a stabilizer. The suitable content of urea or its derivative is 0.5% to 10% by weight.

The composition according to the present invention further comprises surfactant(s). Surfactant(s) (an emulsifier, a dispersing agent, a wetting agent, a spreader, an adjuvant for penetration enhancement, rain fastness, soil leaching control etc.) are a nonionic, a cationic or an anionic surfactant or a combination of these surfactants. It is preferred to use one or more than one kind of surfactant e.g. the combination of a nonionic surfactant and an anionic surfactant; the combination of a nonionic surfactant and a cationic surfactant; or the combination of an anionic surfactant or a cationic surfactant.

Surfactant(s) (a dispersing agent, a wetting agent, a spreader, an adjuvant for penetration enhancement, rain fastness, soil leaching control, etc.) are nonionic or anionic surfactants or a combination of these surfactants. It is preferred to use one or more than one kind of surfactant. Surfactant(s) is selected from the group comprising of, but not limited to, sugar esters such as sorbitan monolaurate, polyoxyethylene sorbitan monolaurate; alkyl polyglucoside such as decyl glucoside; polyoxyethylene alkyl ethers such as polyoxyethylene lauryl ether or polyoxyethylene coconut fatty alcohol ether; polyoxyethylene alkynyl ether such as 2,4,7,9-tetramethyl-5-decyn-4,7-diol ether; polyoxyethylene aryl ethers such as polyoxyethylene nonylphenyl ether or polyoxyethylene tristyrylphenyl ether; polyoxyethylene vegetable oil ethers such as polyoxyethylene castor oil or polyoxyethylene hydrogenated castor oil; polyoxyethylene fatty acid esters such as polyoxyethylene monolaurate, polyoxyethylene distearate or polyoxyethylene resin acid ester; polyoxyethylene polyoxypropylene (EO-PO) block copolymers (such as Pluronic®); polyoxyethylene polyoxypropylene alkyl ether such as polyoxyethylene polyoxypropylene lauryl ether; polyoxyethylene polyoxypropylene aryl ether such as polyoxyethylene polyoxypropylene styrylphenyl ether; polyoxyethylene alkyl amines such as polyoxyethylene stearyl amine; polyoxyethylene fatty acid amide such as lauric acid diethanolamid; fluorinated surfactant; alkyl sulfates such as sodium lauryl sulfate, sodium alkylbenzene sulphonate; polyoxyethylene alkyl ether sulfates such as sodium polyoxyethylene lauryl ether sulfate; polyoxyethylene aryl ether sulfates such as sodium polyoxyethylene nonylphenyl ether sulfate or ammonium polyoxyethylene tristyrylphenyl ether sulfate; aryl sulfonate such as calcium dodecyl benzene sulfonate, sodium naphthalene sulfonate or sodium naphthalene sulfonate formaldehyde condensate; ‘alpha’-olefin sulfonate; alkyl sulfosuccinate such as sodium dioctyl sulfosuccinate; lignin sulfonate such as sodium lignosulfonate; polycarboxylic acid sodium salt; N-methyl fatty acid sarcosinate; polyoxyethylene alkyl ether phosphate; polyoxyethylene aryl ether phosphates such as polyoxyethylene phenyl ether phosphate or polyoxyethylene nonylphenyl ether phosphate; polyoxyethylene polyoxypropylene block copolymer phosphate; graft copolymer such as polymethyl methacrylate-polyethylene glycol graft copolymer. These surfactants may be used alone or in combination thereof.

Examples of preferred surfactants for the present invention, the non-ionic surfactant is selected from the group comprising of polyoxyethylene-polyoxypropylene (EO-PO) block copolymer (such as Genapol® PF-40, Genapol® PF-80); the anionic surfactant is selected from the group comprising of sodium lauryl sulphate, calcium alkyl benzene sulphonate, sodium lauryl ether sulphate; cationic surfactant is selected from the group comprising of cationic hexadecyltrimethylammonium bromide, dodecylltrimethylammonium bromide, tetradecyltrimethylammonium bromide, or benzalkonium chloride or in combination thereof.
The polyoxyethylene-polyoxypropylene block copolymer having the formula as HO-(EO)n-(PO)m-(EO)n-OH where n=20-80 and m=30-60.

The surfactant in the oil phase has HLB value between 4 and 12, and the surfactant in the aqueous phase has HLB value between 12 and 20. The HLB (Hydrophile-Lipophile-Balance) is an empirical scale defined by W. C. Griffin (J. Soc. Cosmetic Chemists, 1, 311 (1949)) which expresses the amphiphilic nature of emulsifying agents (particularly nonionic surfactants). The least hydrophilic surfactants are assigned the lowest HLB values.

The total surfactant content in the emulsion composition is about 0.1% to 40% by weight, preferably about 0.1% to 25% by weight and more preferably about 0.5% to 20% by weight.
Furthermore, auxiliary agent selected from stabilizer(s), co-solvent(s), anti-freezing agent(s), defoamer agent(s), thickener(s), preservative(s), pH adjuster(s), coloring agent(s) and/or odor masking agent(s) may be optionally used.

Stabilizer(s) is selected from the group comprising of, but not limited to, urea or its derivatives selected from 1-methylurea, 1,3-dimethylurea, 1-1-dimethylurea or biuret, epoxidized castor oil, epoxidized rapeseed oil, epoxidized soybean oil, epoxidized cotton seed oil, epoxidized canola oil, epoxidized rice bran oil, epoxidized palm oil, epoxidized coconut oil, epoxidized linseed oil, epoxidized sunflower oil, epoxidized peanut oil, epoxidized thistle oil, p-anisaldehyde, triethanolamine, cocoamine, tallowamine, hexamine, or in combination thereof. It is generally added in an amount of about 0.01% to 10% by weight, particularly about 0.1% to 10% by weight.

Co-solvent(s) is selected from the group comprising of, but not limited to, polyol ethers such as ethylene glycol monopropyl ether, diethylene glycol monomethyl ether, dipropylene glycol dimethyl ether; ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone; ethers such as dipropyl ether, dioxane, tetrahydrofuran; aliphatic hydrocarbons such as normal paraffin, isoparaffin, kerosene, mineral oil; aromatic hydrocarbons such as xylene, toluene, naphthene, solvent naphtha, solvent C9, solvent C10, solvent C12, solvesso 100, solvesso 150, solvesso 200; chlorinated aliphatic or aromatic hydrocarbons such as chlorobenzene, chloroethylene, methylene chloride; esters such as ethyl acetate, diisopropyl phthalate, dimethyl adipate, methyl oleate, methyl tallowate; lactones such as gamma-butyrolactone; amides such as dimethylformamide, N-methyl-2-pyrrolidone, N-octylpyrolidone, N,N-dimethyldecanamide; nitriles such as acetonitrile; organosulfur compound such as dimethyl sulfoxide; vegetable oils such as soybean oil, rapeseed oil, cotton seed oil or a combination thereof. It is generally added in an amount of about 1% to 10% by weight.

Anti-freezing agent(s) is selected from the group comprising of, but not limited to, polyhydric alcohol such as ethylene glycol, polyethylene glycol, diethylene glycol, propylene glycol, glycerol, hexylene glycol, 1-methoxy-2-propanol, cyclohexanol, or in combination thereof. It is generally added in an amount of about 1% to 30% by weight, particularly about 5% to 15% by weight.

Defoamer agent(s) is selected from the group comprising of, but not limited to, silicone based compounds such as polydimethylsiloxane, silicone oil, organic fluorine compounds and polyoxyethylene mixtures or in combination thereof. Commercially available silicone based defoamer agent such as those from Silcolapse® series (Rhone Poulenc), Silfoam® SE 39 (Wacker Chemie), Silfoam® SE 47 (Wacker Chemie), Silfoam® SRE (Wacker Chemie), Silfoam® SD 882 (Wacker Chemie), aqueous emulsion of dialkylpolysiloxanes commercially available as Rhodorsil® 426R (Rhodia Chimie), and a mixture of dialkylpolysiloxanes as an oil, commercially available as Rhodorsil® 416 (Rhodia Chimie), or Silfar® S184 (Wacker Chemie). It is generally added in an amount of about 0.01% to 5% by weight, preferably about 0.05% to 5% by weight and more preferably about 0.05% to 5% by weight.

Thickener(s) is selected from the group comprising of, but not limited to, water-soluble polymers and inorganic fine powder, wherein water-soluble polymer such as xanthan gum, welan gum, guar gum, polyvinyl alcohol, polyvinylpyrrolidone, vinylpyrrolidonel/vinyl acetate copolymers, carboxymethylcellulose, carboxyvinyl polymer, acrylic polymer, starch derivative or polysaccharide; or an inorganic fine powder selected from high purity silica, bentonite, white carbon or in combination thereof. It is generally added in an amount of about 0.01% to 5% by weight, preferably about 0.05% to 5% by weight.

Preservative(s) is selected from the group comprising of, but not limited to, sodium benzoate, potassium sorbate, 4-hydroxybenzoic acid esters, methyl p-methoxybenzoate, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, 1,2-benzisothiazolin-3-one (NIPACIDE BIT 20), benzoic acid, sorbic acid, formaldehyde, in particular a combination of methyl parahydroybenzoate (such as Preserval®M (Laserson & Sabetay, France)) and propyl parahydroxybenzoate (such as Preserval®P (Laserson & Sabetay, France)) or in combination thereof. It is generally added in an amount of about 0.01% to 5% by weight, preferably about 0.1% to 1% by weight.

pH adjuster(s) is selected from the group comprising of, but not limited to, sodium or potassium carbonate, sodium or potassium hydrogen carbonate, sodium or potassium dihydrogenphosphate, disodium or dipotassium hydrogenphosphate, citric acid, maleic acid and triethanolamine or in combination thereof.

Coloring agent(s) is selected from the group comprising of, but not limited to, inorganic pigment such as iron oxide, titanium oxide or Prussian blue; organic dye such as alizarin dye, azo dye, metal phthalocyanine dye or in combination thereof. It is generally added in an amount of about 0.01% to 1% by weight, particularly about 0.1% to 0.5% by weight.

Odor masking agent(s) is selected from the group comprising of, but not limited to, the mixture of numerous natural and synthesis perfumes, such as Perfume® TM 4242 (Technicoflor, France). It is generally added in an amount of about 0.02% to 2% by weight, particularly about 0.1% to 1% by weight.

The composition further comprises an oil phase that optionally comprises of green oil as a carrier. Green oil is selected from the group comprising of, but not limited to, paraffin oil, castor oil, epoxidized castor oil, rapeseed oil, epoxidized rapeseed oil, soybean oil, epoxidized soybean oil, cotton seed oil, epoxidized cotton seed oil, canola oil, epoxidized canola oil, rice bran oil, epoxidized rice bran oil, palm oil, epoxidized palm oil, coconut oil, epoxidized coconut oil, linseed oil, epoxidized linseed oil, sunflower oil, epoxidized sunflower oil, peanut oil, epoxidized peanut oil, thistle oil, epoxidized thistle oil or in combination thereof.

The composition according to the present invention comprises from about 20% to 85% by weight, preferably from about 30% to 85% by weight and more preferably about 40% to 85% by weight of oil phase, based on the total weight of the composition.

In one embodiment, the present invention relates to a method of stabilizing an agrochemical composition comprising of:
addition of one or more agrochemical active ingredient;
addition of one or more stabilizer;
optionally addition of one or more surfactant;
optionally addition of an aqueous medium;
optionally addition of one or more green oil or auxiliary agent;
wherein the stabilizer is selected from the group comprising of urea or its derivatives , triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

The agrochemical active ingredient comprises of one or more organo-phosphorus active ingredient or its combination with one or more pyrethroid active ingredient.
In another embodiment of the present invention, the emulsion composition comprising of:
one or more organo-phosphorus active ingredient,
at least one surfactant,
at least one stabilizer,
an aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In above embodiment, the emulsion composition of organo-phosphorus active ingredient can be used in combination with other active ingredients selected from the group comprising of insecticide(s), fungicide(s), acaricide(s), or nematicide(s) active ingredients.

In an embodiment of the present invention, the emulsion composition comprising of:
one or more active ingredient in combination is selected from the group comprising of organo-phosphorus and pyrethroid,
one or more surfactant,
one or more stabilizer,
an aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In a further embodiment, the organo-phosphorous active ingredient is selected from the group comprising of profenofos, ethion, chlorpyrifos, acephate, demeton-s-methyl, dichlorvos, dimethoate, fenitrothion, fention, malathion, monocrotophos, oxydemeton-methyl, parathion, parathion-methyl, phenoate, phorate, quinalphos, trizophos, chlorethoxyfos or in combination thereof.

In another embodiment, the pyrethroid active ingredient is selected from the group comprising of acrinathrin, allethrin , bioallethrin, barthrin, bifenthrin, kappa-bifenthrin, bioethanomethrin, brofenvalerate, brofluthrinate, bromethrin, butethrin, chlorempenthrin, cyclethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, gamma-cyhalothrin, lambda-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, deltamethrin, dimefluthrin, dimethrin, empenthrin, chloroprallethrin, fenfluthrin, fenpirithrin, fenpropathrin, fenvalerate, esfenvalerate, flucythrinate, fluvalinate, tau-fluvalinate, furamethrin, furethrin, heptafluthrin, imiprothrin, japothrins, kadethrin, methothrin, metofluthrin, epsilon-metofluthrin, momfluorothrin, epsilon-momfluorothrin, pentmethrin, permethrin, biopermethrin, transpermethrin, phenothrin, prallethrin, profluthrin, proparthrin, pyresmethrin, renofluthrin, meperfluthrin, resmethrin, bioresmethrin, cismethrin, tefluthrin, kappa-tefluthrin, terallethrin, tetramethrin, tetramethylfluthrin, tralocythrin, tralomethrin, transfluthrin, valerate, preferably cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin or zeta-cypermethrin.

In another embodiment, the present invention provides the emulsion composition, comprising of:
one or more organo-phosphorus active ingredient,
at least one polyoxyethylene-polyoxypropylene block copolymer; optionally in combination with an anionic surfactant; or a cationic surfactant,
at least one stabilizer,
water,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In an embodiment, the present invention provides the emulsion composition, comprising of:
one or more active ingredient in combination is selected from the group comprising of organo-phosphorus and pyrethroid,
at least one polyoxyethylene-polyoxypropylene block copolymer; optionally in combination with an anionic surfactant; or a cationic surfactant,
at least one stabilizer,
water,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In another embodiment, the present invention provides a method of preparing the emulsion composition, comprising the steps of:
Preparation of an oil phase comprising the steps of:
addition of one or more organo-phosphorus active ingredient,
addition of one or more surfactant,
optionally one or more green oil to obtain the oil phase,
Preparation of an aqueous phase comprising the steps of:
addition of one or more surfactant in an aqueous medium,
addition of one or more stabilizer,
optionally one or more auxiliary agent,
mixing the oil phase into the aqueous phase or vice-versa to obtain the emulsion composition.

In another embodiment, the present invention provides a method of preparing the emulsion composition, comprising the steps of:
Preparation of an oil phase comprising the steps of:
addition of one or more active ingredient in combination is selected from the group comprising of organo-phosphorus and pyrethroid,
addition of one or more surfactant,
optionally one or more green oil to obtain the oil phase,
Preparation of an aqueous phase comprising the steps of:
addition of one or more surfactant in an aqueous medium,
addition of one or more stabilizer,
optionally one or more auxiliary agent,
mixing the oil phase into the aqueous phase or vice-versa to obtain the emulsion composition.

The above mentioned steps for preparing the emulsion composition may be modified by a person skilled in the art.

In a further embodiment of the present invention, the median particle size of the emulsified composition is about 0.1 µm to about 5 µm, preferably about 1 µm.

In the above embodiments of the present invention, the emulsion composition comprises of an aqueous phase and an oil phase; the surfactant in both phases has different hydrophilic-lipophilic balance (HLB) value, wherein the surfactant in oil phase has HLB value between 4 and 12 and the surfactant in aqueous phase has balance has HLB value between 12 and 20.

In an embodiment of the present invention, the emulsion composition remains stable and significantly reduces the rate of decomposition of the organo-phosphorus active ingredient after addition of the stabilizing agent such as urea or its derivative.

In another embodiment of the present invention, the emulsion composition containing the organo-phosphorus active ingredient has water solubility below 100 mg/l at 25 ̊C.
In a preferred embodiment of the present invention, emulsion composition comprising of:
active ingredient profenofos,
one or more surfactant,
one or more stabilizer,
aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In another embodiment of the present invention, emulsion composition comprising of:
active ingredient profenofos,
at least one polyoxyethylene-polyoxypropylene block copolymer; optionally in combination with an anionic surfactant; or a cationic surfactant,
one or more stabilizer,
aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In a further embodiment of the present invention, emulsion composition comprising of:
active ingredient ethion,
one or more surfactant,
one or more stabilizer,
aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In another embodiment of the present invention, emulsion composition comprising of:
active ingredient ethion,
one or more polyoxyethylene-polyoxypropylene block copolymer; optionally in combination with an anionic surfactant; or a cationic surfactant,
one or more stabilizer,
aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In an embodiment of the present invention, emulsion composition comprising of:
active ingredient profenofos and ethion,
one or more surfactant,
one or more stabilizer,
aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In a preferred embodiment of the present invention, emulsion composition comprising of:
profenofos or ethion in combination with cypermethrin or its derivatives thereof,
one or more surfactant,
one or more stabilizer,
aqueous medium,
optionally one or more green oil or auxiliary agent,
wherein the stabilizer is selected from the group comprising of urea or its derivatives, triethanolamine, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde or a combination thereof.

In a preferred embodiment of the present invention provides a process for preparing emulsion composition comprising the steps of:
Preparation of an oil phase comprising the steps of:
addition of profenofos or ethion or a combination thereof,
addition of one or more polyoxyethylene-polyoxypropylene block copolymer having HLB value between 4 and 12, optionally in combination with an anionic or cationic surfactant,
optionally one or more green oil such as paraffin oil to obtain the oil phase,
Preparation of an aqueous phase comprising the steps of:
addition of one or more polyoxyethylene-polyoxypropylene block copolymer having HLB value between 12 and 20, optionally in combination with an anionic or cationic surfactant in the aqueous medium,
addition of one or more stabilizer selected from urea or its derivatives, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde,
optionally one or more auxiliary agent,
mixing the oil phase into the aqueous phase or vice-versa to obtain the emulsion composition with the median particle size about 1 µm.

The above mentioned steps for preparing the emulsion composition may be modified by an ordinary person skilled in the art.

In another embodiment of the present invention provides a process for preparing emulsion composition comprising the steps of:
Preparation of an oil phase comprising the steps of:
addition of profenofos or ethion in combination with cypermethrin or its derivative thereof,
addition of one or more polyoxyethylene-polyoxypropylene block copolymer having HLB value between 4 and 12, optionally in combination with an anionic or cationic surfactant,
optionally one or more green oil such as paraffin oil to obtain the oil phase,
Preparation of an aqueous phase comprising the steps of:
addition of one or more polyoxyethylene-polyoxypropylene block copolymer having HLB value between 12 and 20, optionally in combination with an anionic or cationic surfactant in the aqueous medium,
addition of one or more stabilizer selected from urea or its derivatives, cocoamine, hexamine, tallowamine, epoxidized plant oil, p-anisaldehyde,
optionally one or more auxiliary agent,
mixing the oil phase into the aqueous phase or vice-versa to obtain the emulsion composition with the median particle size about 1 µm.

The composition of the present invention relates to a method of controlling pests comprising applying emulsion composition of organo-phosphorus agrochemical to the pests, or plants or other locuses infected with or frequented by the pests.

The composition of the present invention is used to control pests of cotton (bollworm, loopers, aphids, leaf hoppers (jassids), thrips and red spider mites), tobacco (tobacco budworm), potato (green peach aphids and potato aphids) and tea (red spider mites, pink mites, tea mosquito bugs, looper caterpillars, thrips, jassids).

The present invention is further illustrated by the following examples. These examples describe possible preferred embodiments for illustrative purposes only, but they do not limit the scope of the invention.

Example 1: Profenofos Emulsion with 2% of urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 54.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Urea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 35.75
Total 100.00

The above-mentioned profenofos technical, Genapol PF-40 (surfactant, polyoxyethylene polyoxypropylene block copolymer produced by Clariant International Ltd.) was mixed by an overhead stir in a glass beaker till all materials were completely solved to prepare the oil solution. On the other hand, Genapol PF-80 (surfactant, polyoxyethylene polyoxypropylene block copolymer produced by Clariant International Ltd.) and urea were solved in deionized water under stirring by an overhead stir to prepare the aqueous solution. Into the aqueous solution agitated by overhead homogenizer (Omni GLH, Laboratory Homogenizer), Defoamer RI 100 was added and then the oil solution was slowly added, and the mixture was emulsified till the mass median diameter reaches to about 1μm. Into the emulsion solution, 2% aqueous solution of carboxymethyl cellulose (BLANOSE 7M, ASHLAND) containing NIPACIDE BIT 20 was added and mixed well.

Comparative Example 1: Profenofos Emulsion without urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 54.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 37.75
Total 100.00
The sample of comparative example 1 was prepared in the same manner as Example 1 without urea.

Example 2: Profenofos Emulsion with 2% urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 54.00
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Urea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 29.75
Total 100.00
The sample was prepared in the same manner as Example 1. Paraffin oil was solved into the oil solution.

Comparative Example 2: Profenofos Emulsion without urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 54.00
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 31.75
Total 100.00
The sample of the comparative example 2 was prepared in the same manner as example 2 without urea.

Example 3: Profenofos Emulsion with 2% urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 46.10
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Urea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 4.00
Deionized water 35.65
Total 100.00
The amount of profenofos technical was changed from 54.00% to 46.1%. The sample was prepared in the same manner as Example 1. Paraffin oil was dissolved into the oil solution.

Comparative Example 3: Profenofos Emulsion without urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 46.10
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 4.00
Deionized water 37.65
Total 100.00
The sample of the comparative example 3 was prepared in the same manner as example 3 without urea.

Example 4: Profenofos Emulsion with 8% urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 54.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Urea 8.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 29.75
Total 100.00
The sample of example 4 was prepared in the same manner as example 1 by changing urea 2% to 8%.

Example 5: Profenofos Emulsion with methyl urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 46.10
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Methylurea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 4.00
Deionized water 35.65
Total 100.00
The sample of example 5 was prepared in the same manner as example 2 by changing urea to methyl urea.

Example 6: Profenofos Emulsion with biuret
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 46.10
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Biuret 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 4.00
Deionized water 35.65
Total 100.00
The sample of example 6 was prepared in the same manner as example 2 by changing urea to biuret.
Example 7: Profenofos Emulsion with 2% urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 54.00
Xylene 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Urea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 29.75
Total 100.00
The sample of Example 7 is prepared in the same manner as example 2 by changing paraffin oil to xylene.

Example 8: Profenofos Emulsion with 2% urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 54.00
Epoxidized soybean oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Urea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 29.75
Total 100.00
The sample of Example 8 was prepared in the same manner as example 2 by changing paraffin oil to epoxidized soybean oil.

Example 9: Profenofos and Cypermethrin Emulsion with urea
Ingredients Concentration (% w/w)
Profenofos technical (94.0%) 53.50
Cypermethrin technical (94.0%) 4.83
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.00
EO-PO block copolymer (Genapol PF-80) 4.00
Urea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 26.42
Total 100.00
The sample of example 9 was prepared in the same manner as example 2 by mixing profenofos technical with cypermethrin technical.

Example 10: Ethion Emulsion with 2% urea
Ingredients Concentration (% w/w)
Ethion technical (93.0%) 43.10
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
Urea 2.00
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 40.90
Total 100.00
The sample of Example 10 was prepared in the same manner as example 1 by replacing profenofos technical with ethion technical.
Comparative Example 10: Ethion Emulsion without urea
Ingredients Concentration (% w/w)
Ethion technical (93.0%) 43.10
Paraffin oil 6.00
EO-PO block copolymer (Genapol PF-40) 1.50
EO-PO block copolymer (Genapol PF-80) 4.50
1,2-Benzisothiazol-3(2H)-one (NIPACIDE BIT 20) 0.05
Deformer ethoxylate blend in mineral oil (Defoam RI 100) 0.20
Carboxymethyl cellulose (Blanose 7M) 3% aqueous solution 2.00
Deionized water 42.90
Total 100.00
The sample of comparative example 10 was prepared in the same manner as example 2 by replacing profenofos technical with ethion technical.

Test Example:
Each of the samples obtained in example 1 to 9 and comparative Example 1, 2 and 8 was put in a 50-ml glass bottle and stored for 2 weeks in a 54˚C incubator. The content of profenofos or ethion in the composition before and after storage was measured using HPLC, and the decomposition rate was obtained from the following equation:
Decomposition rate (%)=100-100×(active ingredient content after storage)/(active ingredient content before storage)

The results of the above examples have been shown in Table 1 and 2 provided below:

Table 1:

Sample Profenofos content initial (%) Profenofos content at 54 ̊C after 2 weeks (%) Decomposition rate of Profenofos (%)
Example 1 50.66 49.46 2.37
Comparative Example 1 50.42 28.20 44.07
Example 2 50.36 48.94 2.82
Comparative Example 2 50.58 29.76 41.16
Example 3 44.40 43.33 2.41
Comparative Example 3 43.30 24.92 42.45
Example 4 50.72 49.14 3.12
Example 5 45.32 44.61 1.57
Example 6 45.12 43.01 4.68
Example 7 50.47 49.23 2.46
Example 8 50.26 49.24 2.03
Example 9 50.65 50.08 1.13

Table 2:
Sample Ethion content initial (%) Ethion content at 54 ̊C after 2 weeks (%) Decomposition rate of Ethion (%)
Example 10 40.03 39.73 0.75
Comparative Example 10 40.04 37.96 5.19

As shown in Table 1 and 2, it was found that the stability of an organo-phosphorus active ingredient like profenofos and ethion or combination of profenofos and cypermethrin was improved by adding urea, urea derivatives or biuret.

From the foregoing description, it will be apparent to one ordinarily skilled in the art that many changes and modifications can be made thereto without departing from the spirit or scope of the invention as set forth herein. Accordingly, it is not intended that the scope of the foregoing description be limited to the description set forth above, but rather that such description be construed as encompassing all of the features that reside in the present invention, including all the features and embodiments that would be treated as equivalents thereof by those skilled in the relevant art. 
, Claims:WE CLAIM:

1. A method of stabilizing an agrochemical composition comprising:
a) addition of one or more organo-phosphorus active ingredient;
b) addition of one or more stabilizer;
c) addition of one or more surfactant;
d) addition of an aqueous medium; and
e) addition of one or more green oil or auxiliary agent;
wherein the stabilizer is selected from the group comprising of urea or its derivatives, or a combination thereof.

2. The method as claimed in claim 1, wherein the organo-phosphorus active ingredient is selected from the group comprising of profenofos, ethion, chlorpyrifos, acephate, demeton-s-methyl, dichlorvos, dimethoate, fenitrothion, fention, malathion, monocrotophos, oxydemeton-methyl, parathion, parathion-methyl, phenoate, phorate, quinalphos, trizophos, chlorethoxyfos or a combination thereof.

3. The method as claimed in claim 1, wherein the auxiliary agent is selected from the group comprising of co-solvent(s), anti-freezing agent(s), defoamer agent(s), thickener(s), preservative(s), pH adjuster(s), coloring agent(s) and/or odor masking agent(s).

4. The method as claimed in claim 1, wherein the surfactant is selected from the group comprising of nonionic surfactant, anionic surfactant or cationic surfactant.

5. The method as claimed in claim 4, wherein the non-ionic surfactant is selected from the group comprising of polyoxyethylene-polyoxyproylene block copolymer; the anionic surfactant is selected from the group comprising of sodium lauryl sulphate, calcium alkyl benzene sulphonate, sodium lauryl ether sulphate; cationic surfactant is selected from the group comprising of cationic hexadecyltrimethylammonium bromide, dodecylltrimethylammonium bromide, tetradecyltrimethylammonium bromide, or benzalkonium chloride.

6. The method as claimed in claim 4, wherein the surfactant is used alone or in combination thereof.

7. The method as claimed in claim 1, wherein the green oil is selected from the group comprising of paraffin oil, esters of fatty acids, glycerol fatty acids, plant oil, or epoxidized plant oil.

8. The method as claimed in claim 7, wherein the epoxidized plant oil is selected from the group comprising of the epoxidized form of castor oil, rapeseed oil, soya oil, cotton seed oil, canola oil, ricebran oil, palm oil, coconut oil, linseed oil, sunflower oil, peanut oil, thistle oil, or a combination thereof.

9. The method as claimed in claim 1, wherein the aqueous medium is water, ethanol, methanol, n-butanol, isopropanol, n-propanol, or formic acid.

10. The method as claimed in claim 1, wherein the median particle size of the composition is about 0.1 µm to about 5 µm.

11. An emulsion composition comprising:
a) one or more organo-phosphorus active ingredient;
b) one or more surfactant;
c) one or more stabilizer;
d) an aqueous medium; and
e) optionally one or more green oil or auxiliary agent;
wherein the stabilizer is selected from the group comprising of urea or its derivatives, or a combination thereof.

12. The emulsion composition as claimed in claim 11, wherein the organo-phosphorus active ingredient is selected from the group comprising of profenofos, ethion, chlorpyrifos, acephate, demeton-s-methyl, dichlorvos, dimethoate, fenitrothion, fention, malathion, monocrotophos, oxydemeton-methyl, parathion, parathion-methyl, phenoate, phorate, quinalphos, trizophos, chlorethoxyfos or a combination thereof.

13. The emulsion composition as claimed in claim 12, wherein the organo-phosphorus active ingredient is profenofos, ethion, or a combination thereof.

14. The emulsion composition as claimed in claim 11, wherein the auxiliary agent is selected from the group comprising of co-solvent(s), anti-freezing agent(s), defoamer agent(s), thickener(s), preservative(s), pH adjuster(s), coloring agent(s) and/or odor masking agent(s).

15. The emulsion composition as claimed in claim 11, wherein the surfactant is selected from the group comprising of nonionic surfactant, anionic surfactant or cationic surfactant.

16. The emulsion composition as claimed in claim 15, wherein the non-ionic surfactant is selected from the group comprising of polyoxyethylene-polyoxyproylene block copolymer; the anionic surfactant is selected from the group comprising of sodium lauryl sulphate, calcium alkyl benzene sulphonate, sodium lauryl ether sulphate; cationic surfactant is selected from the group comprising of cationic hexadecyltrimethylammonium bromide, dodecylltrimethylammonium bromide, tetradecyltrimethylammonium bromide, or benzalkonium chloride.

17. The emulsion composition as claimed in claim 15, wherein the surfactant is used alone or in combination thereof.

18. The emulsion composition as claimed in claim 11, wherein the green oil is selected from the group comprising of paraffin oil, esters of fatty acids, glycerol fatty acids, plant oil, or epoxidized plant oil.

19. The emulsion composition as claimed in claim 11, wherein the epoxidized plant oil is selected from the group comprising of the epoxidized form of castor oil, rapeseed oil, soya oil, cotton seed oil, canola oil, ricebran oil, palm oil, coconut oil, linseed oil, sunflower oil, peanut oil, thistle oil, or a combination thereof.

20. The emulsion composition as claimed in claim 11, wherein the aqueous medium is water, ethanol, methanol, n-butanol, isopropanol, n-propanol, or formic acid.

21. The emulsion composition as claimed in claim 11, wherein the median particle size of the emulsified composition is about 0.1 µm to about 5 µm.

22. A process for preparing the emulsion composition as claimed in claim 11, comprising the steps of:
A. Preparation of an oil phase comprising the steps of:
a. addition of one or more organo-phosphorus active ingredient;
b. addition of one or more surfactant; and
c. optionally one or more green oil to obtain the oil phase;
B. Preparation of an aqueous phase comprising the steps of:
I. addition of one or more surfactant in an aqueous medium;
II. addition of one or more stabilizer; and
III. optionally one or more auxiliary agent;
C. mixing the oil phase into the aqueous phase or vice-versa to obtain the emulsion composition.

23. The process as claimed in claim 22, wherein the surfactant in the oil phase having HLB value between 4 and 12.

24. The process as claimed in claim 22, wherein the surfactant in the aqueous phase having HLB value between 12 and 20.