DESC:
FORM 2
THE PATENTS ACT, 1970
(39 OF 1970)
&
The Patents Rules, 2003
COMPLETE SPECIFICATION
(See section 10; rule 13)
1. TITLE OF THE INVENTION – SYNERGISTIC PESTICIDAL COMBINATION OF CHLORANTRANILIPROLE AND LAMBDA-CYHALOTHRIN
2. APPLICANT(S)
a) NAME: MEGHMANI ORGANICS LIMITED
b) NATIONALITY: INDIAN
c) ADDRESS: MEGHMANI HOUSE, BEHIND SAFAL PROFITAIRE, CORPORATE ROAD, PRAHLADNAGAR, AHMEDABAD, GUJARAT, INDIA-380015

3. PREAMBLE TO THE DESCRIPTION
COMPLETE SPECIFICATION
The following specification describes the invention and the manner in which it is to be performed

SYNERGISTIC PESTICIDAL COMBINATION OF CHLORANTRANILIPROLE AND LAMBDA-CYHALOTHRIN

FIELD OF THE INVENTION:

The present invention relates to a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin. The present invention particularly relates to a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin, wherein the said composition is suspension concentrate (SC) and process of preparation thereof.

BACKGROUND OF THE INVENTION:

Pesticides are the chemicals which are applied on plants to kill or eliminate fungus, bacteria, insects, snails, slugs, or weeds. Pesticides are broadly used in agriculture and have facilitated a significant increase in yield of crops and productivity.

In order to control the harmful effects of insects on crops, an extensive range of active insecticide compounds have been developed. Many active insecticide compounds in different formulations are commercially available. The efficacy of these conventional insecticide compounds is restricted in controlling certain groups of insects. Thus, the problem of controlling a broad spectrum of insects by a single product still exists. Presently, several pesticidal formulations are used in comparatively high concentrations and volumes. This leads to higher cost of the product, higher residues on plants and soil causing toxicity and have deleterious effects on the desirable plant species.

Many researchers have developed a variety of chemicals and their formulations which are effective in controlling the insects from destroying the crops. Nevertheless, there is a continuous requirement for novel compositions and methods to control the broad range of insects without harming the desirable plant species, ecosystem and water bodies. Specifically, in view to achieve economical results and eco-friendly compositions, different efforts have been made to maximize the performance of known active ingredients. Also, there is a need for pesticidal compositions which demonstrate synergistic effect at lower cost.

Chlorantraniliprole (3-Bromo-N- [4-chloro-2-methyl-6-(methyl carbamoyl) phenyl]-1-(3-chloro-2-pyridine-2-yl)-1H-pyrazole-5-carboxamide) is a synthetic insecticide of class anthranilic diamide of chemicals.

Chlorantraniliprole is chemically represented as below structure:

The molecular formula of Chlorantraniliprole is C18H14N5O2BrCl2 and molecular weight is 483.15 g/mol and having water solubility of 0.88 mg/L at 20oC. It has a low aqueous solubility and a low volatility. It tends to be highly persistent in the environment. It is highly toxic to aquatic invertebrates, moderately toxic to birds and aquatic plants, and has a low toxicity to bees and earthworms. Chlorantraniliprole has a low oral mammalian toxicity.

Chlorantraniliprole is the insecticide from IRAC (Insecticide Resistance Action Committee) Group 28. Chlorantraniliprole is a fine crystalline off-white powder and is mostly used to control a broad spectrum of pests.

Chlorantraniliprole is a ryanodine receptor modulator and exhibits larvicidal activity as an orally ingested toxicant by targeting and disrupting the Ca2+ balance in the target pests. Chlorantraniliprole is useful to provide protection to a wide variety of crops like corn, cotton, grapes, rice, potatoes etc. Chlorantraniliprole is commercially marketed as suspension concentrate or as water dispersible granules.

Lambda-cyhalothrin is a synthetic pyrethroid insecticide. It has lower aqueous solubility, is relatively volatile and is non-mobile. Based on its chemical properties, lambda-cyhalothrin has low risk of leaching into ground water. Lambda-cyhalothrin is listed in the 3A group according to the Insecticide Resistance Action Committee (IRAC) classification.

The IUPAC name of Lambda-cyhalothrin is (R)-a-cyano-3-phenoxybenzyl (1S)-cis-3-[(Z)-2-chloro-3,3,3–trifluoropropenyl]- 2, 2- dimethyl cyclopropane carboxylate and (S)-a-cyano-3-phenoxybenzyl (1R)-cis-3-[(Z)-2-chloro-3, 3, 3 - trifluoropropenyl] -2, 2-dimethylcyclopropanecarboxylate and the molecular formula is C23H19ClF3NO3. The relative Molecular mass of Lambda-cyhalothrin is 449.85 g / mol. The solubility of Lambda-cyhalothrin in water is 0.005 mg/l at 20ºC.

Lambda-cyhalothrin is chemically represented as below structure:

Lambda-cyhalothrin is used to control a wide spectrum of insect pests, e.g. aphids, beetles, thrips, Lepidoptera larvae, Coleoptera larvae and adults, etc. Lambda-cyhalothrin is used to provide protection from pests in cereals, hops, ornamentals, potatoes, vegetables, cotton and other crops. It also provides good control of insect-borne plant viruses and is also used for controlling insect pests in public health.

Lambda-cyhalothrin is a non-systemic insecticide with contact and stomach action and repellent properties. It gives rapid knockdown and long residual activity. Lambda-cyhalothrin is commercially marketed as encapsulated suspension, emulsion concentrate, oil in water emulsion, Ultra-low volume formulation, water dispersible granule or wettable powder.

In India or anywhere in the world, in agricultural production, using synthetic or chemical agent is the most effective means in order to control pests. However, the main disadvantage of such insecticide is that on long run, the insects develop resistance towards that insecticide and as a result to produce effective result, higher concentration of the insecticide is to be used. Here again using higher dose of insecticide may result in some detrimental effect to soil as well as environment. Therefore, in general practice, usually combination of insecticide with another insecticide or another herbicide or fungicide is used in different concentration as per requirement.

However, when combination of one or more insecticide are used, the main challenge comes is to develop a formulation or composition which is stable, easy to use, safe and cost effective with superior efficacy. The present invention satisfies the existing needs, as well as others, and generally overcomes the deficiencies found in the prior art.

CN101971866 describes a compound insecticidal micro-emulsion comprising the following raw materials in percentage by weight: 0.1 to 45% of Chlorantraniliprole, 0.2 to 30% of natural pyrethrin, 4 to 26% of emulsifier, 2 to 10% of penetrant, 2 to 8% of stabilizer, 3 to 16% of co-solvent and 24 to 68% of deionized water. This prior art does describe the combination of Chlorantraniliprole with natural pyrethrin in micro-emulsion formulation but nowhere discloses combination of Chlorantraniliprole and a synthetic pyrethroid specifically Lambda-cyhalothrin in suspension concentrate formulation.

Indian Patent 201821040633 disclose a novel synergistic insecticidal composition comprising: component (A) Chlorantraniliprole in an amount between 1% to 10 % (w/w); component (B) at least one pesticide selected from Diafenthiuron in an amount between 10% to 50 % (w/w) or Thiocyclam hydrogen oxalate in an amount between 30 % to 60 % (w/w); component (C) optionally sulphur in an amount of 10-30% (w/w); component (D) in active excipients selected form anti-freezing, emulsifiers, antifoaming agent, stabilizing agent, viscosity agent, filler, anticaking agent, wetting and dispersing agent. This prior art nowhere discloses the combination of Chlorantraniliprole and Lambda-cyhalothrin in suspension concentrate formulation.

Indian patent 201821040632 relates to Suspo-Emulsion (SE) formulation of synergistic insecticidal composition comprises: (a) Chlorantraniliprole in amount between 1% to 10 % (w/w); (b) at least one pesticide selected from Fenobucarb in amount between 35% to 45 % (w/w) or Pyriproxyfen in amount between 1% to 10 % (w/w); c) anti-freezing agent in an amount of 0.1-8 % w/w; d) one or more emulsifiers in an amount of 0.1-8% w/w; e) anti foaming agent in an amount of 0.1-5 % w/w; f) stabilizing agent in an amount of 0.1-5 % w/w; g) viscosity modifier agent in an amount of 0.1-8 % w/w; h) filler in amount of 30-80 % w/w (Quantity sufficient); i) one or more solvent in an amount of 5-35%w/w. This prior art does not comprise the combination of Chlorantraniliprole and Lambda-cyhalothrin in suspension concentrate formulation.

WO2021076693 relates to an insecticidal concentrate composition, the composition comprising Bifenthrin and Chlorantraniliprole, wherein (i) the weight ratio of bifenthrin to Chlorantraniliprole on an active ingredient basis is from about 10:1 to greater than 1.5:1 or from less than 1.5:1 to about 1:10; (ii) the bifenthrin concentration is from about 10 wt.% to about 60 wt.%; and (iii) the composition is a liquid, a dispersion, a suspension, or an emulsion This prior art does describe the combination of Chlorantraniliprole with Bifenthrin but nowhere discloses the combination of Chlorantraniliprole and Lambda-cyhalothrin in suspension concentrate formulation.

Indian patent 202021004186 discloses a composition comprising Chlorantraniliprole and Diflubenzuron in a ratio of about 1:8. This prior art nowhere discloses the combination of Chlorantraniliprole and Lambda-cyhalothrin in suspension concentrate formulation.

However, there is no formulation or composition available where Chlorantraniliprole and Lambda-cyhalothrin in suspension concentrate formulation which is stable and yet effective.

In the present invention, inventors have arrived to a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin in suspension concentrate formulation and the process of preparation which is stable, effective and overcome all the problems mentioned in prior art as described herein.

OBJECT OF THE INVENTION

The principal object of the present invention is to provide a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin.

Another object of the present invention is to provide a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin, wherein the said composition is in suspension concentrate (SC) formulation.

Yet another object of the present invention is to provide a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin, wherein the said composition is in suspension concentrate (SC) formulation which is effective against a broad spectrum of pests and insects.

Another object of the present invention is to provide a process to manufacture synergistic pesticidal composition of Chlorantraniliprole and Lambda-cyhalothrin in suspension concentrate (SC) formulation.

Yet another object of the present invention is to provide a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin which is stable.

Another object of the present invention is to provide a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin which is easy to manufacture.

Another object of the present invention is to provide a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin which is effective, farmer friendly and in use at field.

Yet another object of the present invention is to provide a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin, wherein the said composition is in suspension concentrate (SC) formulation which provides enhanced pesticide effect on pests, insects and microbes which in turn results in better yield of crops.

SUMMARY OF THE INVENTION
The present invention discloses a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin, wherein the said composition is in suspension concentrate (SC) formulation comprising: Chlorantraniliprole Technical in the range of 5-15% w/w, Lambda-cyhalothrin Technical in the range of 2-10% w/w, Surfactant in the range of 0.5-5% w/w, Dispersing agent in the range of 0.5-5% w/w and Fillers or adjuvants. The present invention more particularly discloses a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin and process of preparation thereof which is easy to manufacture, effective on broad spectrum of pests, lower the rate of application of the active ingredients, enhanced pesticide effect on pests and cost effective.

DETAILED DESCRIPTION OF THE INVENTION

The detailed description set forth below is intended as a description of exemplary embodiments and is not intended to represent the only forms in which the exemplary embodiments may be constructed and/or utilized. The description sets forth the functions and the sequence of steps for constructing and/or operating the exemplary embodiments. However, it is to be understood that the same or equivalent functions and sequences which may be accomplished by different exemplary methods are also intended to be encompassed within the spirit and scope of the invention.

As defined herein, all scientific and technical terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention belongs. Although any process and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention, the preferred methods and materials are now described.

As stated in the present invention herein, the singular forms “a”, “an” and “the” specifically, also encompass the plural forms of the terms to which they refer, unless the content clearly dictates otherwise. The term “about” is used herein to means approximately, in the region of, roughly, or around.

As used herein, the terms "pesticide effect" and "pesticide activity" mean any direct or indirect action on the target pest that results in reduced feeding damage on the seeds, roots, shoots and foliage of plants as a result of application of said formulation.

As used herein, the term "pest" means any insect, rodent and microbes targeted for treatment with a formulation of the invention. Target pest means any insect, rodent and microbes that are harmful for the plants and decrease the productivity of plants.

As used herein, the term "QS" is an abbreviation for Quantum Satis meaning “Add as much of this ingredient as is needed to achieve the desired result, but not more”.

The present invention is all about providing a synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin, wherein the said composition is suspension concentrate (SC) and process of preparation thereof.

As per one embodiment, the present invention provides a synergistic pesticidal Suspension Concentrate (SC) combination comprising Chlorantraniliprole and Lambda-cyhalothrin with the following mass percentage of the composition:

Sr. No. Raw Material Concentration range (% w/w)
1 Chlorantraniliprole Technical (Purity 97.00%) 5-15
2 Lambda-cyhalothrin Technical (Purity 95% w/w) 2-10
3 Dispersing agent 0.5-5
4 Surfactant 0.5-5
5 Fillers/ adjuvants QS

Active ingredient is the actual chemical in the product mixture that controls the pests, insects and microbes. Active ingredient plays a key role in the functioning of the product mixture.

As per one embodiment, the active ingredient for the present invention is Chlorantraniliprole and Lambda-cyhalothrin, wherein the concentration range of Chlorantraniliprole is in the range of 5-15% w/w and Lambda-cyhalothrin is in the range of 2-10% w/w in SC formulation.

A dispersing agent is a substance which adsorbs onto the surface of particles and helps to preserve the state of dispersion of the particles and prevents them from re-aggregating. Dispersing agents are added to agrochemical formulations to facilitate dispersion and suspension during manufacture, and to ensure the particles re-disperse into vehicle or carrier.

As per one embodiment, the concentration range of dispersing agent in the pesticidal composition of the present invention is in the range of 0.5-5% w/w. The dispersing agent in the present invention is selected from a group of modified styrene Acrylic polymer, Polyalkoxylated butyl ether and sodium salt of Alkylated naphthalene sulfonate.

Wetting agents/ surfactants are chemical agents which lower the surface tension of liquid by a considerable amount in order to allow it to spread upon the penetrating surface. It is well within the competence of those skilled in the art to determine whether a particular surface-active agent (surfactant) is a wetting agent or not.

As per one embodiment, wetting agent for present invention is selected from group consisting of Trisiloxane ethoxylate, ethoxylated fatty alcohol, polydimethyl siloxane or combination thereof.

The Suspending agent helps active agent stay suspended in the formulation and prevent sedimentation at the bottom of the container. The suspending agent helps formulation to remain stable without problem of sedimentation.

As per one embodiment, suspending agent for the present invention is selected from group consisting of Silicon Dioxide, colloidal silicon dioxide, Polyalkoxylated butyl ether or combination thereof.

An antifreeze is defined as an additive that, when added to a water-based formulation, will reduce the freezing point of the formulation.

As per one embodiment, anti-freezing agent for the present invention is selected from group consisting of Polypropylene glycol, monoethylene glycol, propylene glycol, polyethylene glycol and ethylene glycol or combination thereof.

An adjuvant is an additive which is added to make the formulations more effective, that improves or enhances application, performance, safety, storage, or handling of an active ingredient.

As per one embodiment, the pesticide formulation also contains one or more additional adjuvants selected from polysaccharides, anti-foaming agent, anti-microbial agent, thickening agent, biocides and vehicle.

In yet another embodiment of the present invention, the benefits of the synergistic pesticidal combination of Chlorantraniliprole and Lambda-cyhalothrin and its process of preparation are described as follows:
1. Easy to manufacture.
2. Effective on wide range of pests and broadening the spectrum of pesticidal activity to other pests.
3. Reduction in the rate of application of the active ingredients.
4. Adequate control of the pests with the aid of the compositions according to the invention, even at a rate of application at which the individual compounds are totally ineffective.
5. Product is adapted to use practices by farmers.
6. Cost effective
7. SC formulation is safe to use formulation, with higher efficacy rate compared to other existing formulations.

In yet another embodiment of the present invention there is provided a process for preparation of Chlorantraniliprole and Lambda-cyhalothrin Suspension Concentrate (SC) formulation.

The following examples are meant to illustrate the present invention. The examples are presented to exemplify the invention and are not to be considered as limiting the scope of invention.

EXAMPLE
Example 1: Pesticidal Suspension Concentrate (SC) composition of the present invention.
Sr No. Chemical Composition Percent (% w/w) Function
1 Chlorantraniliprole Technical (Purity-97.00%) 9.55 Active toxicant
2 Lambda-cyhalothrin Technical (Purity-95.00%) 5.00 Active toxicant
3 Modified Styrene Acrylic polymer 3.00 Dispersing agent
4 Ethoxylated Fatty Alcohol 2.00 Wetting agent
5 Polyalkoxylated butyl ether 0.50 Dispersing and Suspending agent
6 Sodium Salt of Alkylated Naphthalene Sulfonate 0.50 Dispersing agent
7 Trisiloxane ethoxylate 2.00 Wetting and spreading agent
8 Polydimethylsiloxane 0.50 Antifoaming Agent
9 Silicon Dioxide 0.50 Suspending and anti-cracking agent
10 Polysaccharides 0.20 Thickening agent
11 1,2-benzisothiazol-3-one 0.25 Biocide
12 Polypropylene glycol 5.00 Anti-freezing agent
13 DM Water 71.00 Carrier
Total 100.00

Example 2: Stability study of Example 1
2.1: Heat stability for 14 days at 54 degrees centigrade & cold stability 7 days at 0 degrees centigrade
Parameters Specification (in house) Initial Heat stability at 54±2 degrees centigrade Cold stability at 0±2 degrees centigrade
Chlorantraniliprole content % by mass 9.50 to 10.50 10.25 10.28 10.12
Lambda-cyhalothrin content % by mass 4.75 to 5.50 5.21 5.18 5.20
Chlorantraniliprole suspensibility % mini. 80 98.41 98.19 98.12
Lambda-cyhalothrin suspensibility % mini. 80 95.10 95.19 95.05
pH range (1% aqueous suspension) 5.50 to 7.50 7.10 7.05 7.11
Pourability 95% min. 98.27 98.10 97.97
Specific gravity 1.05- 1.15 1.1 1.098 1.101
Viscosity at spindle no. 62,20 rpm 350-800 cps 598 612 647
Particle size (micron) D50<3,
D90< 10 2.4, 5.9 2.3, 6.1 2.4, 6.5
Persistent foam ml (after 1 minute) max. 60 11 9 8
2.2: Room Temperature storage stability up to 12 months
Parameters Specification (in house) 1 month 6 months 12 months
Chlorantraniliprole content % by mass 9.50 to 10.50 10.17 10.33 10.24
Lambda-cyhalothrin content % by mass 4.75 to 5.50 5.21 5.14 5.19
Chlorantraniliprole suspensibility % mini. 80 98.23 98.29 98.47
Lambda-cyhalothrin suspensibility % mini. 80 95.56 95.83 95.73
pH range (1% aqueous suspension) 5.50 to 7.50 7.08 7.04 7.11
Pourability 95% min. 98.46 98.32 98.33
Specific gravity 1.05- 1.15 1.102 1.103 1.107
Viscosity at spindle no. 6220 rpm 350-800 cps 615 633 648
Particle size (micron) D50 < 3, D90< 10 2.2, 6.6 2.2,6.9 2.3,6.3
Persistent foam ml (after 1 minute) max. 60 10 8 10

Example 3: Field Trial Studies
Field trial experiments were conducted to evaluate the efficacy of Chlorantraniliprole and Lambda-cyhalothrin SC in comparison to its solo applications. The observations were recorded by counting the no. of pests before the treatment, 7 days after of treatment and after 15 days after treatment on the crops. The % population reduction/control of pests was calculated by below formula:
% Population reduction/ Control = (Mean population in Untreated plot) - (Mean population in Treated Plot) X 100
(Mean population in Untreated Plot)

Example 3(a): Efficacy of Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC on Soybean semi looper (Chrysodeixis acuta) population control.
Location: Bangalore, Karnataka, India
Season: Kharif-2021
Crop: Soybean
Date of sowing: 15/06/2021
Date of application: 04/08/2021
Treatment details Dose Pre-Treatment 7 DAT* 15 DAT % Reduction / Control
T1 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 175 ml/ha 7.75 6.75 7.25 42.27
T2 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 200 ml/ha 7.25 3.25 2.50 76.29
T3 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 225 ml/ha 7.50 2.75 2.75 77.32
T4 Chlorantraniliprole 18.5% SC 150 ml/ha 7.75 9.75 7.25 29.90
T5 Lambda cyhalothrin 5% EC 500 ml/ha 6.75 8.25 7.50 35.05
T6 Untreated control 7.75 10.75 16.25 ---
CV** (%) 13.11 19.79 19.56
CD*** 5% 1.71 2.41 2.23
Note: *DAT: Days After Treatment, **CV= Co-efficient of Variation, *** CD= Critical Difference

The results of the above experiment show that the SC formulation of Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% show synergistic effect in terms of % Population reduction / Control of semi looper’s in soybean. Maximum synergism is obtained at the dosage application rate of 225 ml/ ha with 77.32% population reduction / control of semi looper’s.

Example 3(b): Efficacy of Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC on Cotton Bollworm (Helicoverpa armigera) population control.
Location: Raichur, Karnataka, India
Season: Kharif-2021
Crop: Cotton
Date of sowing: 07/06/2021
Date of application: 23/08/2021
Treatment details Dose Pre-Treatment 7 DAT* 15 DAT % Reduction / Control
T1 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 175 ml/ha 17.00 11.50 10.00 36.30
T2 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 200 ml/ha 18.00 9.00 3.25 63.70
T3 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 225 ml/ha 17.00 8.75 3.75 62.96
T4 Chlorantraniliprole 18.5% SC 150 ml/ha 16.75 10.25 9.50 41.48
T5 Lambda-cyhalothrin 5% EC 500 ml/ha 16.75 11.25 10.50 35.56
T6 Untreated control 16.00 16.75 17.00 -----
CV** (%) 16.32 11.56 16.76
CD*** 5% 4.07 2.26 2.62
Note: *DAT: Days After Treatment, **CV= Co-efficient of Variation, *** CD= Critical Difference

The results of the above experiment show that the SC formulation of Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% show synergistic effect in terms of Percent Population reduction / Control of bollworms in cotton. Maximum synergism is obtained at the dosage application rate of 200 ml/ ha with 63.70% population reduction/ control of bollworm.

Example 3(c): Efficacy of Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC on Rice Yellow Stem Borer (Scirpophaga incertulas) population control.
Location: Bellary (Kurugod), Karnataka, India
Season: Kharif-2021
Crop: Rice
Date of sowing: 07/06/2021
Date of application: 20/08/2021
Treatment details Dose Pre-Treatment 7 DAT* 15 DAT % Reduction / Control
T1 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 175 ml/ha 72.75 52.00 37.25 47.19
T2 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 200 ml/ha 75.00 37.25 12.25 70.71
T3 Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% SC 225 ml/ha 74.50 32.25 10.50 74.70
T4 Chlorantraniliprole 18.5% SC 150 ml/ha 72.50 44.50 19.50 62.13
T5 Lambda cyhalothrin 5% EC 500 ml/ha 72.00 45.75 20.25 60.95
T6 Untreated control 73.50 82.00 87.00 -----
CV** (%) 3.53 9.86 22.71
CD*** 5% 4.51 8.40 12.30
Note: *DAT: Days After Treatment, **CV= Co-efficient of Variation, *** CD= Critical Difference

The results of the above experiment show that the SC formulation of Chlorantraniliprole 10% + Lambda-Cyhalothrin 5% show synergistic effect in terms of percent population reduction / control of stem borer pest in Rice. Maximum efficacy / synergism is exhibited at 225 ml/ ha dose application rate with 74.70% population reduction / control of rice yellow stem borer.

Technical advancements:
The present disclosure described herein above has several technical advantages including, but not limited to, the realization of:
• A synergistic pesticidal Suspension Concentrate formulation comprising Chlorantraniliprole and Lambda-Cyhalothrin;
• A synergistic pesticidal Suspension Concentrate formulation comprising Chlorantraniliprole and Lambda-Cyhalothrin which is stable and is in a ready to use form;

From the results in Examples 1-3, the pesticidal combination of Chlorantraniliprole and Lambda-Cyhalothrin in SE formulation claimed in the present invention has a synergistic effect on control of pests.

Throughout this specification, the word “comprise”, or variations such as “comprises” or “comprising”, will be understood to imply the inclusion of a stated element, integer or step, or group of elements, integers or steps, but not exclusion of any other element, integer or step, or group of elements, integers or steps.

Although the foregoing invention has been described in some way by way of illustration and example of purposes of clarity of understanding, it will be readily apparent to those of ordinary skill in the art in light of the teachings of this invention that certain changes and modifications may be made thereto.

Dated this 1st day of May, 2023
Signature:
Name: Patel Ankit (CEO)
,CLAIMS:We Claim:

1. A synergistic pesticide composition comprising:
a) Chlorantraniliprole Technical (Purity-97.00%) in the concentration range of 5-15% w/w,
b) Lambda-cyhalothrin Technical (Purity-95.00%) in the concentration range of 2-10% w/w,
c) One or more Dispersing agent in the concentration range of 0.5-5% w/w,
d) One or more Wetting agent in the concentration range of 0.5-3% w/w,
e) One or more Suspending agent in the concentration range of 0.5-2% w/w,
f) One or more Anti-freezing agent in the concentration range of 3-6% w/w,
g) One or more Adjuvants in the concentration range of 0.05-5% w/w.
h) DM water

2. The synergistic pesticide composition as claimed in claim 1, wherein the formulation is Suspension Concentrate (SC) formulation.

3. The synergistic pesticide composition as claimed in claim 1, wherein Chlorantraniliprole Technical (Purity-97.00%) is in the concentration range of 5-15% w/w.

4. The synergistic pesticide composition as claimed in claim 1, wherein Lambda-cyhalothrin Technical (Purity-95.00%) is in the concentration range of 2-10% w/w.

5. The synergistic pesticide composition as claimed in claim 1, wherein the dispersing agent is selected from a group of modified styrene Acrylic polymer, Polyalkoxylated butyl ether and sodium salt of Alkylated naphthalene sulfonate or combination thereof in the concentration range of 0.5- 5% w/w.

6. The synergistic pesticide composition as claimed in claim 1, wherein the wetting agent is selected from group consisting of Trisiloxane ethoxylate, ethoxylated fatty alcohol, polydimethyl siloxane or combination thereof in the concentration range of 0.5-3% w/w.

7. The synergistic pesticide composition as claimed in claim 1, wherein the suspending agent is selected from group consisting of Silicon Dioxide, colloidal silicon dioxide, Polyalkoxylated butyl ether or combination thereof in the concentration of 0.5-2% w/w.

8. The synergistic pesticide composition as claimed in claim 1, wherein the anti-freezing agent is selected from group consisting of Polypropylene glycol, monoethylene glycol, propylene glycol, polyethylene glycol and ethylene glycol or combination thereof in the concentration range of 3-6% w/w.

9. A pesticidal formulation of Chlorantraniliprole and Lambda-cyhalothrin comprising:
a) 9.55% w/w of Chlorantraniliprole Technical,
b) 5.00% w/w of Lambda-cyhalothrin Technical,
c) 0.5-5.0% w/w of combination of Modified Styrene Acrylic polymer, Polyalkoxylated butyl ether and Alkylated naphthalene sulfonate sodium salt,
d) 0.5-3.0% w/w of combination of Ethoxylated Fatty Alcohol and
Trisiloxane ethoxylate,
e) 0.5-2.0% w/w of combination of Polyalkoxylated butyl ether and Silicon dioxide
f) 0.5% w/w of Polydimethyl siloxane
g) 0.2% w/w of Polysaccharides
h) 0.25% w/w of 1, 2- benzisothiazol-3-one
i) 5.0% w/w of Polypropylene glycol
j) DM Water.

Dated this 1st day of May, 2023
Signature:
Name: Patel Ankit (CEO)
Meghmani Organics Limited