DESC:FIELD OF THE INVENTION:
The present invention relates to synergistic pesticidal composition comprising of bioactive amounts of (A) at least one Diacylhydrazines group of insecticide; (B) at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds; (C) fungicide(s) selected from class of respiration process inhibitors, and sterol biosynthesis inhibitors. The present invention further relates to process of preparing the said composition along with at least one inactive excipients and formulation thereof.

BACKGROUND OF THE INVENTION:
Combination of insecticides and fungicides are used to broaden the spectrum of control of insect and fungal pests, reduce dosage, thereby reducing environmental impact, and decrease chances of development of resistance. The combination of insecticides and fungicides at times demonstrate an additive or synergistic effect that results in an improved control on the pests.

Insecticide or pesticides are used widely and very frequently in commercial agriculture
and have enabled an enormous increase in crop yields and product quality which
ultimately increased the ease to farmers in term of economic advantage as well as ease of farming activities.

There are many combinations of insecticides and fungicides known in the art for the control of soil borne pests. For example, EP2731430 patent relates to pesticidal composition comprising methoxyfenozide and mancozeb along with different pesticidal compound for the effectively increasing crop yield of agricultural plants under pressure by effectively treating various pathogens.

US8969392 patent relates to a pesticide composition intended for protecting plants, crops or seeds against phyto-pathogenic fungi or damaging insects, and the corresponding methods of treatment using the said composition. Further it relates to a composition comprising methoxyfenozide and mancozeb with different pesticidal compounds including fungicides of different class.
EP2094087 relates to a pesticidal composition comprising an anthranilamide compound or its salt and other insecticide and/or fungicide. This patent discloses the composition comprising methoxyfenozide and mancozeb along with several mixture of insecticide and fungicide.

CA2757055 relates to solid form of pesticidal composition comprising an Azocyclic Amide. The patent further discosed the composition comprising of methoxyfenozide and mancozeb along with several mixture of insecticides and fungicides.

There is however a need for improvement of these combinations. Single active combinations used over a long period of time has resulted in resistance. With the onset of resistance to certain pests, there is a need in the art for a combination of actives that decreases chances of resistance and improves the spectrum of disease and pest control.

However still there is a need for a composition comprises at least one Diacylhydrazines group of insecticide; at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds; and a fungicides having various mode of action which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.

In general use, the pesticide actives are used in the form of a dilute aqueous composition because it can attain a good interaction with the target organism, such as plants, fungi and insects. However, most active pesticide compounds that are used as pesticides are only sparingly or even insoluble in water. The low solubility of such compounds present the challenges and difficulties to formulator in formulating pesticide compounds in stable formulations that can be easily stored for a long time and which still have a high stability and effective activity until end use. This problem especially occurs and may get worsen if more than one active compound is present in the composition.
Therefore, one object of the present invention is to provide improved combinations of insecticides and fungicides for the control of soil borne pests. Another object of the present invention is to provide a method and a composition for controlling insect pests and fungal diseases around plant propagation material.
Yet another object of the present invention is to provide improved combinations of insecticides and fungicides that promote plant health.
Embodiment of the present invention can ameliorate one or more of the above mentioned problems.

Inventors of the present invention have surprisingly found that the synergistic
pesticidal composition comprising of at least one Diacylhydrazines group of insecticide; at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds; and fungicides having various mode of action as described herein provides solution to the above mentioned problems.

SUMMARY OF THE INVENTION
Therefore an aspect of the present invention provides a pesticidal composition comprising (A) at least one Diacylhydrazines group of insecticide; (B) at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds; (C) fungicides selected from class of nucleic acid synthesis inhibitors, cytoskeleton and motor protien inhibitors, amino acid and protein synthesis inhibitors, respiration process inhibitors, signal transduction inhibitors, lipid synthesis and membrane integrity disruptors, sterol biosynthesis inhibitors; and one or more customary formulation adjuvants.
More particularly an aspect of the present invention provides a pesticidal composition comprising (A) at least one Diacylhydrazines group of insecticide selected from Chromafenozide, Halofenozide, Methoxyfenozide, Tebufenozide; (B) at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds selected from the group of copper hydroxide, copper oxychloride, copper (II) sulphate, Bordeaux mixture, copper salicylate, cuprous oxide; ferbam, mancozeb, maneb, metiram, propineb, thiram, zinc thiazole, zineb, ziram, phthalimides-captan, captafol, folpet, chloronitriles (phthalonitriles)-chlorothalonil, sulfamides-dichlofluanid, tolylfluanid, bis guanidines-guazatine, iminoctadine, triazines-anilazine, quinones (anthraquinones)-dithianon, quinoxalines-chinomethionat /quinomethionate, maleimide-fluoroimide, thiocarbamate –methasulfocarb; (C) fungicides selected from class of nucleic acid synthesis inhibitors, cytoskeleton and motor protien inhibitors, amino acid and protein synthesis inhibitors, respiration process inhibitors, signal transduction inhibitors, lipid synthesis and membrane integrity disruptors, sterol biosynthesis inhibitors selected individually one from the group of Cyproconazole, Difenoconazole, Epoxiconazole, Flutriafol, Hexaconazole, Tebuconazole, Tetraconazole, Propiconazole, Prothioconazole and second from the group Azoxystrobin, Picoxystrobin, Pyraclostrobin, Kresoxim methyl, Trifloxystrobin, Benzovindiflupyr, Bixafen, Fluxapyroxad, Isopyrazam, Penthiopyrad, Isoflucypyram, Boscalid; and one or more customary formulation adjuvants.
Accordingly, in a further aspect of the present invention is containing the pesticide composition of (A) Methoxyfenozide; (B) multi-site fungicide Mancozeb; (C) fungicides selected from Cyproconazole, Difenoconazole, Epoxiconazole, Flutriafol, Hexaconazole, Tebuconazole, Tetraconazole, Propiconazole, Prothioconazole, Azoxystrobin, Picoxystrobin, Pyraclostrobin, Kresoxim methyl, Trifloxystrobin, Benzovindiflupyr, Bixafen, Fluxapyroxad, Isopyrazam, Penthiopyrad, Isoflucypyram, Boscalid.
Accordingly, in a further aspect, the present invention provides a method of protecting a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time against pathogenic damage or pest damage by applying to the plant propagation material a composition comprising a pesticidal composition defined in the first aspect.
Accordingly, in a yet another aspect the said pesticidal composition is formulations selected from Capsule suspension (CS), Dispersible concentrate (DC), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion for seed treatment (ES), Emulsion, oil in water (EW), Flowable suspension/concentrate for seed treatment (FS), Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), Solution for seed treatment (LS), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (= flowable concentrate) (SC), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Water soluble powder (SP), Water dispersible granule (WG or WDG), Wettable powder (WP), Water dispersible powder for slurry treatment (WS), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), A mixed formulation of CS and EW (ZW); comprising (A) Methoxyfenozide; (B) Mancozeb; (C) fungicides selected from Cyproconazole, Difenoconazole, Epoxiconazole, Flutriafol, Hexaconazole, Tebuconazole, Tetraconazole, Propiconazole, Prothioconazole, Azoxystrobin, Picoxystrobin, Pyraclostrobin, Kresoxim methyl, Trifloxystrobin, Benzovindiflupyr, Bixafen, Fluxapyroxad, Isopyrazam, Penthiopyrad, Isoflucypyram, Boscalid; and one or more customary formulation adjuvants such as a) dispersant b) wetting agent c) anti-foaming agent d) biocides e) anti-freezing agent f) suspending agent g) thickener h) coating agent and i) buffering agent.
As per one embodiment formulation for the pesticidal composition is selected from Capsule suspension (CS), Dispersible concentrate (DC), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion for seed treatment (ES), Emulsion, oil in water (EW), Flowable suspension/concentrate for seed treatment (FS), Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), Solution for seed treatment (LS), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (flowable concentrate) (SC), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Water soluble powder (SP), Water dispersible granule (WG or WDG), Wettable powder (WP), Water dispersible powder for slurry treatment (WS), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), A mixed formulation of CS and EW (ZW).
The remainder of the aqueous formulation is preferably wholly water but may comprise other materials, such as inorganic salts. The formulation is preferably, completely free from organic solvents.
Accordingly, in a first aspect, the present invention provides a pesticidal composition comprising (A) Methoxyfenozide; (B) Mancozeb; (C) fungicides selected from Cyproconazole, Difenoconazole, Epoxiconazole, Flutriafol, Hexaconazole, Tebuconazole, Tetraconazole, Propiconazole, Prothioconazole, Azoxystrobin, Picoxystrobin, Pyraclostrobin, Kresoxim methyl, Trifloxystrobin, Benzovindiflupyr, Bixafen, Fluxapyroxad, Isopyrazam, Penthiopyrad, Isoflucypyram, Boscalid shows synergistic activity.

DETAILED DESCRIPTION OF THE INVENTION:
The term "synergistic", as used herein, refers the combined action of two or more active
agents blended together and administered conjointly that is greater than the sum of their
individual effects.
"Bioactive amounts” as mentioned herein means that amount which, when applied treatment of crops, is sufficient to effect such treatment.
Therefore an aspect of the present invention provides a pesticidal composition comprising (A) at least one Diacylhydrazines group of insecticide; (B) at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds; (C) fungicides selected from class of nucleic acid synthesis inhibitors, cytoskeleton and motor protein inhibitors, amino acid and protein synthesis inhibitors, respiration process inhibitors, signal transduction inhibitors, lipid synthesis and membrane integrity disruptors, sterol biosynthesis inhibitors; and one or more customary formulation adjuvants.
In an embodiment of the present invention the fungicides from the nucleic acid synthesis inhibitors class may be selected from benalaxyl, benalaxyl-M (=kiralaxyl), furalaxyl, metalaxyl, metalaxyl-M (=mefenoxam), oxadixyl, ofurace, bupirimate, dimethirimol, ethirimol, hymexazole, octhilinone and oxolinic acid.
In an embodiment of the present invention the fungicides from the cytoskeleton and motor protien inhibitors class may be selected from benomyl, carbendazim, fuberidazole, thiabendazole, thiophanate, thiophanate-methyl, diethofencarb, zoxamide, ethaboxam, pencycuron, fluopicolide, fluopimomide, phenamacril, metrafenone, pyriofenone
In a further embodiment of the present invention the fungicides from amino acid and protein synthesis inhibitors class may be selected from cyprodinil, mepanipyrim, pyrimethanil, blasticidin-S, kasugamycin, streptomycin, oxytetracycline.
In yet another embodiment of the present invention the fungicides from respiration process inhibitors class may be selected from diflumetorim, tolfenpyrad, fenazaquin, benodanil, flutolanil, mepronil, isofetamid, fluopyram, fenfuram, carboxin, oxycarboxin, thifluzamide, benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, furametpyr, inpyrfluxam, isopyrazam, penflufen, penthiopyrad, sedaxane, isoflucypram, pydiflumetofen, boscalid, pyraziflumid, azoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, picoxystrobin, pyraoxystrobin, mandestrobin, pyraclostrobin, pyrametostrobin, triclopyricarb, kresoxim-methyl, trifloxystrobin, dimoxystrobin, fenaminstrobi metominostrobin, orysastrobin, famoxadone, fluoxastrobin, fenamidone, pyribencarb, metyltetraprole, cyazofamid, amisulbrom, fenpicoxamid, binapacryl, meptyldinocap, dinocap, fluazinam, fentin acetate, fentin chloride, fentin hydroxide, silthiofam, ametoctradin.
In a further embodiment of the present invention the fungicides from signal transduction inhibitors class may be selected from quinoxyfen, proquinazid, fenpiclonil, fludioxonil, chlozolinate, dimethachlone, iprodione, procymidone, vinclozolin.
In a further embodiment of the present invention the fungicides from lipid synthesis and membrane integrity disruptors class may be selected from edifenphos, iprobenfos (IBP), pyrazophos, isoprothiolane, biphenyl, chloroneb dicloran, quintozene (PCNB), tecnazene (TCNB,) tolclofos-methyl,,etridiazole,,iodocarb, propamocarb, prothiocarb, plant oils (mixtures): eugenol, geraniol, thymol, natamycin (pimaricin), oxathiapiprolin, fluoxapiprolin.
In a further embodiment of the present invention the fungicides from sterol biosynthesis inhibitors class may be selected from triforine, pyrifenox, pyrisoxazole, fenarimol, nuarimol, imazalil, oxpoconazole, pefurazoate, prochloraz, triflumizole, azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, prothioconazole, aldimorph, dodemorph, fenpropimorph, tridemorph, fenpropidin, piperalin, spiroxamine, fenhexamid, fenpyrazamine, pyributicarb, naftifine, terbinafine.
In a further embodiment of the present invention the fungicides from melanin synthesis inhibitors class may be selected from fthalide, pyroquilon, tricyclazole, carpropamid, diclocymet, fenoxanil, tolprocarb.
In a further embodiment of the present invention the fungicides from cell wall biosynthesis inhibitors class may be selected from polyoxin, dimethomorph, flumorph, pyrimorph, benthiavalicarb, iprovalicarb, valifenalate, mandipropamid.
In a further embodiment of the present invention the fungicides from host plant defence inductors class may be selected from acibenzolar-S-methyl, probenazole, tiadinil isotianil, laminarin, extract from Reynoutria sachalinensis (giant knotweed), Bacillus mycoides, isolate J, fosetyl-Al, phosphorous acid and salts.
In a further embodiment of the present invention the fungicides with unknown mode of action may be selected from Cymoxanil, Teclofthalam, Triazoxide, Flusulfamide, Diclomezine, Cyflufenamid, Dodine, Flutianil, Ferimzone, Tebufloquin, Picarbutrazox, Validamycin.
More particularly an aspect of the present invention provides a pesticidal composition comprising (A) at least one Diacylhydrazines group of insecticide selected from the group of selected from Chromafenozide, Halofenozide, Methoxyfenozide, Tebufenozide; (B) at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds selected from the group of copper hydroxide, copper oxychloride, copper (II) sulphate, Bordeaux mixture, copper salicylate, cuprous oxide; ferbam, mancozeb, maneb, metiram, propineb, thiram, zinc thiazole, zineb, ziram, phthalimides-captan, captafol, folpet, chloronitriles (phthalonitriles)-chlorothalonil, sulfamides-dichlofluanid, tolylfluanid, bis guanidines-guazatine, iminoctadine, triazines-anilazine, quinones (anthraquinones)-dithianon, quinoxalines-chinomethionat /quinomethionate, maleimide-fluoroimide, thiocarbamate -methasulfocarb, (C) fungicides selected from Cyproconazole, Difenoconazole, Epoxiconazole, Flutriafol, Hexaconazole, Tebuconazole, Tetraconazole, Propiconazole, Prothioconazole, Azoxystrobin, Picoxystrobin, Pyraclostrobin, Kresoxim methyl, Trifloxystrobin, Benzovindiflupyr, Bixafen, Fluxapyroxad, Isopyrazam, Penthiopyrad, Isoflucypyram, Boscalid; and one or more customary formulation adjuvants.
The present invention provides formulation for the aforesaid composition and method of preparation thereof.
Diacylhydrazines group of insecticide:
Diacylhydrazines are the only group of ecdysone receptor agonist insecticides, which induce premature molting in insects by mimicking the action of the molting hormone ecdysone. Activity is limited to Lepidoptera and Coleoptera, and because the compounds do not penetrate the cuticle well, they must be ingested. Ecdysone receptor agonists provide rapid control in comparison to most insect growth regulators, causing feeding cessation within 3 to 14 hours.
Diacylhydrazine insecticides bind in the ecdysone binding site of the ecdysone receptor-usp dimer, causing it to activate ecdysone-responsive genes that are normally activated during molting and metamorphosis. One of the earliest symptoms, occurring within 3 to 14 hours, is feeding cessation, a normal effect of ecdysone that allows insects to clear food from the gut in preparation for molting. Separation of the old cuticle from the epidermis and synthesis of the new cuticle begins during this time also. The continued activation of ecdysone receptors, in contrast to the brief activation by the pulse of ecdysone in a normal molt, does not allow the proper timing of gene activation. This results in an improperly formed cuticle and mouth parts that are soft and mushy and unable to break the insect out of the old cuticle. The selectivity of diacylhydrazines for Lepidoptera is due in large part to the high selectivity for lepidopteran ecdysone receptors.
Environmental and Toxicological Considerations: Diacylhydrazines have an excellent environmental profile, are essentially non-toxic to mammals and other vertebrates, and have exhibited low toxicity towards most non-target invertebrates, including beneficial insects and bees
Methoxyfenozide is a carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by 3-methoxy-2-methylbenzoyl, 3,5-dimethylbenzoyl, and tert-butyl groups respectively. It has a role as an environmental contaminant, a xenobiotic and an insecticide. It is a carbohydrazide and a monomethoxybenzene. It derives from a N'-benzoyl-N-(tert-butyl) benzohydrazide. Methoxyfenozide acts as an insecticide on insects that may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.

Dithiocarbamate group of Fungicide:
Dithiocarbamates are derivatives of sulfur-containing dithiocarbamic acid, in combination with zinc salts, ferric salts, and manganese salts. Dithiocarmates are organic fungicides have the reputation of being safer and less persistent than some of their inorganic counterparts, and they are often used at very low doses. These fungicides have greater efficacy, better stability, and less phytotoxicity than elemental sulfur. Their toxicity derives from the formation of the isothiocyanate radical (–N = C = S–) in breakdown.
Mancozeb is a dithiocarbamate non-systemic agricultural fungicide with multi-site, protective action on contact. It controls many fungal diseases in a wide range of field crops, fruits, nuts, vegetables, and ornamentals. It is marketed as Penncozeb, Trimanoc, Vondozeb, Dithane, Manzeb, Nemispot, and Manzane. Mancozeb is chemically known as a zinc;manganese(2+);N-[2 (sulfidocarbothioylamino) ethyl]carbamodithioate. Mancozeb reacts with, and inactivates, the sulfhydryl groups of amino acids and enzymes within fungal cells, resulting in disruption of lipid metabolism, respiration, and production of adenosine triphosphate.
The present inventors believe that the combination of the present invention surprisingly results in a synergistic action. The combinations of the present invention allow for a broad spectrum of pest control and has surprisingly improved plant vigour and yield. The broad spectrum of the present combination also provides a solution for preventing the development of resistance.
Therefor the aspect of the present invention provides the pesticide composition of active ingrdients comprising (A) Methoxyfenozide; (B) Mancozeb; (C) fungicides selected from Cyproconazole, Difenoconazole, Epoxiconazole, Flutriafol, Hexaconazole, Tebuconazole, Tetraconazole, Propiconazole, Prothioconazole, Azoxystrobin, Picoxystrobin, Pyraclostrobin, Kresoxim methyl, Trifloxystrobin, Benzovindiflupyr, Bixafen, Fluxapyroxad, Isopyrazam, Penthiopyrad, Isoflucypyram, Boscalid; are present in following different preferred combination in present pesticidal composition as below:

Active
Ingredient A
Insecticide Active
Ingredient B
Fungicide
Active Ingredient C
Fungicide
Methoxyfenozide Mancozeb Cyproconazole
Methoxyfenozide Mancozeb Difenoconazole
Methoxyfenozide Mancozeb Epoxiconazole
Methoxyfenozide Mancozeb Flutriafol
Methoxyfenozide Mancozeb Hexaconazole
Methoxyfenozide Mancozeb Tebuconazole
Methoxyfenozide Mancozeb Tetraconazole
Methoxyfenozide Mancozeb Propiconazole
Methoxyfenozide Mancozeb Prothioconazole
Methoxyfenozide Mancozeb Azoxystrobin
Methoxyfenozide Mancozeb Picoxystrobin
Methoxyfenozide Mancozeb Pyraclostrobin
Methoxyfenozide Mancozeb Kresoxim methyl
Methoxyfenozide Mancozeb Trifloxystrobin
Methoxyfenozide Mancozeb Benzovindiflupyr
Methoxyfenozide Mancozeb Bixafen
Methoxyfenozide Mancozeb Fluxapyroxad
Methoxyfenozide Mancozeb Isopyrazam
Methoxyfenozide Mancozeb Penthiopyrad
Methoxyfenozide Mancozeb Isoflucypyram
Methoxyfenozide Mancozeb Boscalid
Methoxyfenozide Mancozeb Fluopyram
Methoxyfenozide Mancozeb Cyproconazole Azoxystrobin
Methoxyfenozide Mancozeb Cyproconazole Picoxystrobin
Methoxyfenozide Mancozeb Cyproconazole Pyraclostrobin
Methoxyfenozide Mancozeb Cyproconazole Kresoxim methyl
Methoxyfenozide Mancozeb Cyproconazole Trifloxystrobin
Methoxyfenozide Mancozeb Cyproconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Cyproconazole Bixafen
Methoxyfenozide Mancozeb Cyproconazole Fluxapyroxad
Methoxyfenozide Mancozeb Cyproconazole Isopyrazam
Methoxyfenozide Mancozeb Cyproconazole Penthiopyrad
Methoxyfenozide Mancozeb Cyproconazole Isoflucypyram
Methoxyfenozide Mancozeb Cyproconazole Boscalid
Methoxyfenozide Mancozeb Cyproconazole Fluopyram
Methoxyfenozide Mancozeb Difenoconazole Azoxystrobin
Methoxyfenozide Mancozeb Difenoconazole Picoxystrobin
Methoxyfenozide Mancozeb Difenoconazole Pyraclostrobin
Methoxyfenozide Mancozeb Difenoconazole Kresoxim methyl
Methoxyfenozide Mancozeb Difenoconazole Trifloxystrobin
Methoxyfenozide Mancozeb Difenoconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Difenoconazole Bixafen
Methoxyfenozide Mancozeb Difenoconazole Fluxapyroxad
Methoxyfenozide Mancozeb Difenoconazole Isopyrazam
Methoxyfenozide Mancozeb Difenoconazole Penthiopyrad
Methoxyfenozide Mancozeb Difenoconazole Isoflucypyram
Methoxyfenozide Mancozeb Difenoconazole Boscalid
Methoxyfenozide Mancozeb Difenoconazole Fluopyram
Methoxyfenozide Mancozeb Epoxiconazole Azoxystrobin
Methoxyfenozide Mancozeb Epoxiconazole Picoxystrobin
Methoxyfenozide Mancozeb Epoxiconazole Pyraclostrobin
Methoxyfenozide Mancozeb Epoxiconazole Kresoxim methyl
Methoxyfenozide Mancozeb Epoxiconazole Trifloxystrobin
Methoxyfenozide Mancozeb Epoxiconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Epoxiconazole Bixafen
Methoxyfenozide Mancozeb Epoxiconazole Fluxapyroxad
Methoxyfenozide Mancozeb Epoxiconazole Isopyrazam
Methoxyfenozide Mancozeb Epoxiconazole Penthiopyrad
Methoxyfenozide Mancozeb Epoxiconazole Isoflucypyram
Methoxyfenozide Mancozeb Epoxiconazole Boscalid
Methoxyfenozide Mancozeb Epoxiconazole Fluopyram
Methoxyfenozide Mancozeb Flutriafol Azoxystrobin
Methoxyfenozide Mancozeb Flutriafol Picoxystrobin
Methoxyfenozide Mancozeb Flutriafol Pyraclostrobin
Methoxyfenozide Mancozeb Flutriafol Kresoxim methyl
Methoxyfenozide Mancozeb Flutriafol Trifloxystrobin
Methoxyfenozide Mancozeb Flutriafol Benzovindiflupyr
Methoxyfenozide Mancozeb Flutriafol Bixafen
Methoxyfenozide Mancozeb Flutriafol Fluxapyroxad
Methoxyfenozide Mancozeb Flutriafol Isopyrazam
Methoxyfenozide Mancozeb Flutriafol Penthiopyrad
Methoxyfenozide Mancozeb Flutriafol Isoflucypyram
Methoxyfenozide Mancozeb Flutriafol Boscalid
Methoxyfenozide Mancozeb Flutriafol Fluopyram
Methoxyfenozide Mancozeb Hexaconazole Azoxystrobin
Methoxyfenozide Mancozeb Hexaconazole Picoxystrobin
Methoxyfenozide Mancozeb Hexaconazole Pyraclostrobin
Methoxyfenozide Mancozeb Hexaconazole Kresoxim methyl
Methoxyfenozide Mancozeb Hexaconazole Trifloxystrobin
Methoxyfenozide Mancozeb Hexaconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Hexaconazole Bixafen
Methoxyfenozide Mancozeb Hexaconazole Fluxapyroxad
Methoxyfenozide Mancozeb Hexaconazole Isopyrazam
Methoxyfenozide Mancozeb Hexaconazole Penthiopyrad
Methoxyfenozide Mancozeb Hexaconazole Isoflucypyram
Methoxyfenozide Mancozeb Hexaconazole Boscalid
Methoxyfenozide Mancozeb Hexaconazole Fluopyram
Methoxyfenozide Mancozeb Tebuconazole Azoxystrobin
Methoxyfenozide Mancozeb Tebuconazole Picoxystrobin
Methoxyfenozide Mancozeb Tebuconazole Pyraclostrobin
Methoxyfenozide Mancozeb Tebuconazole Kresoxim methyl
Methoxyfenozide Mancozeb Tebuconazole Trifloxystrobin
Methoxyfenozide Mancozeb Tebuconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Tebuconazole Bixafen
Methoxyfenozide Mancozeb Tebuconazole Fluxapyroxad
Methoxyfenozide Mancozeb Tebuconazole Isopyrazam
Methoxyfenozide Mancozeb Tebuconazole Penthiopyrad
Methoxyfenozide Mancozeb Tebuconazole Isoflucypyram
Methoxyfenozide Mancozeb Tebuconazole Boscalid
Methoxyfenozide Mancozeb Tebuconazole Fluopyram
Methoxyfenozide Mancozeb Tetraconazole Azoxystrobin
Methoxyfenozide Mancozeb Tetraconazole Picoxystrobin
Methoxyfenozide Mancozeb Tetraconazole Pyraclostrobin
Methoxyfenozide Mancozeb Tetraconazole Kresoxim methyl
Methoxyfenozide Mancozeb Tetraconazole Trifloxystrobin
Methoxyfenozide Mancozeb Tetraconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Tetraconazole Bixafen
Methoxyfenozide Mancozeb Tetraconazole Fluxapyroxad
Methoxyfenozide Mancozeb Tetraconazole Isopyrazam
Methoxyfenozide Mancozeb Tetraconazole Penthiopyrad
Methoxyfenozide Mancozeb Tetraconazole Isoflucypyram
Methoxyfenozide Mancozeb Tetraconazole Boscalid
Methoxyfenozide Mancozeb Tetraconazole Fluopyram
Methoxyfenozide Mancozeb Propiconazole Azoxystrobin
Methoxyfenozide Mancozeb Propiconazole Picoxystrobin
Methoxyfenozide Mancozeb Propiconazole Pyraclostrobin
Methoxyfenozide Mancozeb Propiconazole Kresoxim methyl
Methoxyfenozide Mancozeb Propiconazole Trifloxystrobin
Methoxyfenozide Mancozeb Propiconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Propiconazole Bixafen
Methoxyfenozide Mancozeb Propiconazole Fluxapyroxad
Methoxyfenozide Mancozeb Propiconazole Isopyrazam
Methoxyfenozide Mancozeb Propiconazole Penthiopyrad
Methoxyfenozide Mancozeb Propiconazole Isoflucypyram
Methoxyfenozide Mancozeb Propiconazole Boscalid
Methoxyfenozide Mancozeb Propiconazole Fluopyram
Methoxyfenozide Mancozeb Prothioconazole Azoxystrobin
Methoxyfenozide Mancozeb Prothioconazole Picoxystrobin
Methoxyfenozide Mancozeb Prothioconazole Pyraclostrobin
Methoxyfenozide Mancozeb Prothioconazole Kresoxim methyl
Methoxyfenozide Mancozeb Prothioconazole Trifloxystrobin
Methoxyfenozide Mancozeb Prothioconazole Benzovindiflupyr
Methoxyfenozide Mancozeb Prothioconazole Bixafen
Methoxyfenozide Mancozeb Prothioconazole Fluxapyroxad
Methoxyfenozide Mancozeb Prothioconazole Isopyrazam
Methoxyfenozide Mancozeb Prothioconazole Penthiopyrad
Methoxyfenozide Mancozeb Prothioconazole Isoflucypyram
Methoxyfenozide Mancozeb Prothioconazole Boscalid
Methoxyfenozide Mancozeb Prothioconazole Fluopyram
Methoxyfenozide Propineb Cyproconazole
Methoxyfenozide Propineb Difenoconazole
Methoxyfenozide Propineb Epoxiconazole
Methoxyfenozide Propineb Flutriafol
Methoxyfenozide Propineb Hexaconazole
Methoxyfenozide Propineb Tebuconazole
Methoxyfenozide Propineb Tetraconazole
Methoxyfenozide Propineb Propiconazole
Methoxyfenozide Propineb Prothioconazole
Methoxyfenozide Propineb Azoxystrobin
Methoxyfenozide Propineb Picoxystrobin
Methoxyfenozide Propineb Pyraclostrobin
Methoxyfenozide Propineb Kresoxim methyl
Methoxyfenozide Propineb Trifloxystrobin
Methoxyfenozide Propineb Benzovindiflupyr
Methoxyfenozide Propineb Bixafen
Methoxyfenozide Propineb Fluxapyroxad
Methoxyfenozide Propineb Isopyrazam
Methoxyfenozide Propineb Penthiopyrad
Methoxyfenozide Propineb Isoflucypyram
Methoxyfenozide Propineb Boscalid
Methoxyfenozide Propineb Fluopyram
Methoxyfenozide Propineb Cyproconazole Azoxystrobin
Methoxyfenozide Propineb Cyproconazole Picoxystrobin
Methoxyfenozide Propineb Cyproconazole Pyraclostrobin
Methoxyfenozide Propineb Cyproconazole Kresoxim methyl
Methoxyfenozide Propineb Cyproconazole Trifloxystrobin
Methoxyfenozide Propineb Cyproconazole Benzovindiflupyr
Methoxyfenozide Propineb Cyproconazole Bixafen
Methoxyfenozide Propineb Cyproconazole Fluxapyroxad
Methoxyfenozide Propineb Cyproconazole Isopyrazam
Methoxyfenozide Propineb Cyproconazole Penthiopyrad
Methoxyfenozide Propineb Cyproconazole Isoflucypyram
Methoxyfenozide Propineb Cyproconazole Boscalid
Methoxyfenozide Propineb Cyproconazole Fluopyram
Methoxyfenozide Propineb Difenoconazole Azoxystrobin
Methoxyfenozide Propineb Difenoconazole Picoxystrobin
Methoxyfenozide Propineb Difenoconazole Pyraclostrobin
Methoxyfenozide Propineb Difenoconazole Kresoxim methyl
Methoxyfenozide Propineb Difenoconazole Trifloxystrobin
Methoxyfenozide Propineb Difenoconazole Benzovindiflupyr
Methoxyfenozide Propineb Difenoconazole Bixafen
Methoxyfenozide Propineb Difenoconazole Fluxapyroxad
Methoxyfenozide Propineb Difenoconazole Isopyrazam
Methoxyfenozide Propineb Difenoconazole Penthiopyrad
Methoxyfenozide Propineb Difenoconazole Isoflucypyram
Methoxyfenozide Propineb Difenoconazole Boscalid
Methoxyfenozide Propineb Difenoconazole Fluopyram
Methoxyfenozide Propineb Epoxiconazole Azoxystrobin
Methoxyfenozide Propineb Epoxiconazole Picoxystrobin
Methoxyfenozide Propineb Epoxiconazole Pyraclostrobin
Methoxyfenozide Propineb Epoxiconazole Kresoxim methyl
Methoxyfenozide Propineb Epoxiconazole Trifloxystrobin
Methoxyfenozide Propineb Epoxiconazole Benzovindiflupyr
Methoxyfenozide Propineb Epoxiconazole Bixafen
Methoxyfenozide Propineb Epoxiconazole Fluxapyroxad
Methoxyfenozide Propineb Epoxiconazole Isopyrazam
Methoxyfenozide Propineb Epoxiconazole Penthiopyrad
Methoxyfenozide Propineb Epoxiconazole Isoflucypyram
Methoxyfenozide Propineb Epoxiconazole Boscalid
Methoxyfenozide Propineb Epoxiconazole Fluopyram
Methoxyfenozide Propineb Flutriafol Azoxystrobin
Methoxyfenozide Propineb Flutriafol Picoxystrobin
Methoxyfenozide Propineb Flutriafol Pyraclostrobin
Methoxyfenozide Propineb Flutriafol Kresoxim methyl
Methoxyfenozide Propineb Flutriafol Trifloxystrobin
Methoxyfenozide Propineb Flutriafol Benzovindiflupyr
Methoxyfenozide Propineb Flutriafol Bixafen
Methoxyfenozide Propineb Flutriafol Fluxapyroxad
Methoxyfenozide Propineb Flutriafol Isopyrazam
Methoxyfenozide Propineb Flutriafol Penthiopyrad
Methoxyfenozide Propineb Flutriafol Isoflucypyram
Methoxyfenozide Propineb Flutriafol Boscalid
Methoxyfenozide Propineb Flutriafol Fluopyram
Methoxyfenozide Propineb Hexaconazole Azoxystrobin
Methoxyfenozide Propineb Hexaconazole Picoxystrobin
Methoxyfenozide Propineb Hexaconazole Pyraclostrobin
Methoxyfenozide Propineb Hexaconazole Kresoxim methyl
Methoxyfenozide Propineb Hexaconazole Trifloxystrobin
Methoxyfenozide Propineb Hexaconazole Benzovindiflupyr
Methoxyfenozide Propineb Hexaconazole Bixafen
Methoxyfenozide Propineb Hexaconazole Fluxapyroxad
Methoxyfenozide Propineb Hexaconazole Isopyrazam
Methoxyfenozide Propineb Hexaconazole Penthiopyrad
Methoxyfenozide Propineb Hexaconazole Isoflucypyram
Methoxyfenozide Propineb Hexaconazole Boscalid
Methoxyfenozide Propineb Hexaconazole Fluopyram
Methoxyfenozide Propineb Tebuconazole Azoxystrobin
Methoxyfenozide Propineb Tebuconazole Picoxystrobin
Methoxyfenozide Propineb Tebuconazole Pyraclostrobin
Methoxyfenozide Propineb Tebuconazole Kresoxim methyl
Methoxyfenozide Propineb Tebuconazole Trifloxystrobin
Methoxyfenozide Propineb Tebuconazole Benzovindiflupyr
Methoxyfenozide Propineb Tebuconazole Bixafen
Methoxyfenozide Propineb Tebuconazole Fluxapyroxad
Methoxyfenozide Propineb Tebuconazole Isopyrazam
Methoxyfenozide Propineb Tebuconazole Penthiopyrad
Methoxyfenozide Propineb Tebuconazole Isoflucypyram
Methoxyfenozide Propineb Tebuconazole Boscalid
Methoxyfenozide Propineb Tebuconazole Fluopyram
Methoxyfenozide Propineb Tetraconazole Azoxystrobin
Methoxyfenozide Propineb Tetraconazole Picoxystrobin
Methoxyfenozide Propineb Tetraconazole Pyraclostrobin
Methoxyfenozide Propineb Tetraconazole Kresoxim methyl
Methoxyfenozide Propineb Tetraconazole Trifloxystrobin
Methoxyfenozide Propineb Tetraconazole Benzovindiflupyr
Methoxyfenozide Propineb Tetraconazole Bixafen
Methoxyfenozide Propineb Tetraconazole Fluxapyroxad
Methoxyfenozide Propineb Tetraconazole Isopyrazam
Methoxyfenozide Propineb Tetraconazole Penthiopyrad
Methoxyfenozide Propineb Tetraconazole Isoflucypyram
Methoxyfenozide Propineb Tetraconazole Boscalid
Methoxyfenozide Propineb Tetraconazole Fluopyram
Methoxyfenozide Propineb Propiconazole Azoxystrobin
Methoxyfenozide Propineb Propiconazole Picoxystrobin
Methoxyfenozide Propineb Propiconazole Pyraclostrobin
Methoxyfenozide Propineb Propiconazole Kresoxim methyl
Methoxyfenozide Propineb Propiconazole Trifloxystrobin
Methoxyfenozide Propineb Propiconazole Benzovindiflupyr
Methoxyfenozide Propineb Propiconazole Bixafen
Methoxyfenozide Propineb Propiconazole Fluxapyroxad
Methoxyfenozide Propineb Propiconazole Isopyrazam
Methoxyfenozide Propineb Propiconazole Penthiopyrad
Methoxyfenozide Propineb Propiconazole Isoflucypyram
Methoxyfenozide Propineb Propiconazole Boscalid
Methoxyfenozide Propineb Propiconazole Fluopyram
Methoxyfenozide Propineb Prothioconazole Azoxystrobin
Methoxyfenozide Propineb Prothioconazole Picoxystrobin
Methoxyfenozide Propineb Prothioconazole Pyraclostrobin
Methoxyfenozide Propineb Prothioconazole Kresoxim methyl
Methoxyfenozide Propineb Prothioconazole Trifloxystrobin
Methoxyfenozide Propineb Prothioconazole Benzovindiflupyr
Methoxyfenozide Propineb Prothioconazole Bixafen
Methoxyfenozide Propineb Prothioconazole Fluxapyroxad
Methoxyfenozide Propineb Prothioconazole Isopyrazam
Methoxyfenozide Propineb Prothioconazole Penthiopyrad
Methoxyfenozide Propineb Prothioconazole Isoflucypyram
Methoxyfenozide Propineb Prothioconazole Boscalid
Methoxyfenozide Propineb Prothioconazole Fluopyram
Methoxyfenozide Chlorothalonil Cyproconazole
Methoxyfenozide Chlorothalonil Difenoconazole
Methoxyfenozide Chlorothalonil Epoxiconazole
Methoxyfenozide Chlorothalonil Flutriafol
Methoxyfenozide Chlorothalonil Hexaconazole
Methoxyfenozide Chlorothalonil Tebuconazole
Methoxyfenozide Chlorothalonil Tetraconazole
Methoxyfenozide Chlorothalonil Propiconazole
Methoxyfenozide Chlorothalonil Prothioconazole
Methoxyfenozide Chlorothalonil Azoxystrobin
Methoxyfenozide Chlorothalonil Picoxystrobin
Methoxyfenozide Chlorothalonil Pyraclostrobin
Methoxyfenozide Chlorothalonil Kresoxim methyl
Methoxyfenozide Chlorothalonil Trifloxystrobin
Methoxyfenozide Chlorothalonil Benzovindiflupyr
Methoxyfenozide Chlorothalonil Bixafen
Methoxyfenozide Chlorothalonil Fluxapyroxad
Methoxyfenozide Chlorothalonil Isopyrazam
Methoxyfenozide Chlorothalonil Penthiopyrad
Methoxyfenozide Chlorothalonil Isoflucypyram
Methoxyfenozide Chlorothalonil Boscalid
Methoxyfenozide Chlorothalonil Fluopyram
Methoxyfenozide Chlorothalonil Cyproconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Cyproconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Cyproconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Cyproconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Cyproconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Cyproconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Cyproconazole Bixafen
Methoxyfenozide Chlorothalonil Cyproconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Cyproconazole Isopyrazam
Methoxyfenozide Chlorothalonil Cyproconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Cyproconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Cyproconazole Boscalid
Methoxyfenozide Chlorothalonil Cyproconazole Fluopyram
Methoxyfenozide Chlorothalonil Difenoconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Difenoconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Difenoconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Difenoconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Difenoconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Difenoconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Difenoconazole Bixafen
Methoxyfenozide Chlorothalonil Difenoconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Difenoconazole Isopyrazam
Methoxyfenozide Chlorothalonil Difenoconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Difenoconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Difenoconazole Boscalid
Methoxyfenozide Chlorothalonil Difenoconazole Fluopyram
Methoxyfenozide Chlorothalonil Epoxiconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Epoxiconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Epoxiconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Epoxiconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Epoxiconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Epoxiconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Epoxiconazole Bixafen
Methoxyfenozide Chlorothalonil Epoxiconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Epoxiconazole Isopyrazam
Methoxyfenozide Chlorothalonil Epoxiconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Epoxiconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Epoxiconazole Boscalid
Methoxyfenozide Chlorothalonil Epoxiconazole Fluopyram
Methoxyfenozide Chlorothalonil Flutriafol Azoxystrobin
Methoxyfenozide Chlorothalonil Flutriafol Picoxystrobin
Methoxyfenozide Chlorothalonil Flutriafol Pyraclostrobin
Methoxyfenozide Chlorothalonil Flutriafol Kresoxim methyl
Methoxyfenozide Chlorothalonil Flutriafol Trifloxystrobin
Methoxyfenozide Chlorothalonil Flutriafol Benzovindiflupyr
Methoxyfenozide Chlorothalonil Flutriafol Bixafen
Methoxyfenozide Chlorothalonil Flutriafol Fluxapyroxad
Methoxyfenozide Chlorothalonil Flutriafol Isopyrazam
Methoxyfenozide Chlorothalonil Flutriafol Penthiopyrad
Methoxyfenozide Chlorothalonil Flutriafol Isoflucypyram
Methoxyfenozide Chlorothalonil Flutriafol Boscalid
Methoxyfenozide Chlorothalonil Flutriafol Fluopyram
Methoxyfenozide Chlorothalonil Hexaconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Hexaconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Hexaconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Hexaconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Hexaconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Hexaconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Hexaconazole Bixafen
Methoxyfenozide Chlorothalonil Hexaconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Hexaconazole Isopyrazam
Methoxyfenozide Chlorothalonil Hexaconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Hexaconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Hexaconazole Boscalid
Methoxyfenozide Chlorothalonil Hexaconazole Fluopyram
Methoxyfenozide Chlorothalonil Tebuconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Tebuconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Tebuconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Tebuconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Tebuconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Tebuconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Tebuconazole Bixafen
Methoxyfenozide Chlorothalonil Tebuconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Tebuconazole Isopyrazam
Methoxyfenozide Chlorothalonil Tebuconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Tebuconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Tebuconazole Boscalid
Methoxyfenozide Chlorothalonil Tebuconazole Fluopyram
Methoxyfenozide Chlorothalonil Tetraconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Tetraconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Tetraconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Tetraconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Tetraconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Tetraconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Tetraconazole Bixafen
Methoxyfenozide Chlorothalonil Tetraconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Tetraconazole Isopyrazam
Methoxyfenozide Chlorothalonil Tetraconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Tetraconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Tetraconazole Boscalid
Methoxyfenozide Chlorothalonil Tetraconazole Fluopyram
Methoxyfenozide Chlorothalonil Propiconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Propiconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Propiconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Propiconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Propiconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Propiconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Propiconazole Bixafen
Methoxyfenozide Chlorothalonil Propiconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Propiconazole Isopyrazam
Methoxyfenozide Chlorothalonil Propiconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Propiconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Propiconazole Boscalid
Methoxyfenozide Chlorothalonil Propiconazole Fluopyram
Methoxyfenozide Chlorothalonil Prothioconazole Azoxystrobin
Methoxyfenozide Chlorothalonil Prothioconazole Picoxystrobin
Methoxyfenozide Chlorothalonil Prothioconazole Pyraclostrobin
Methoxyfenozide Chlorothalonil Prothioconazole Kresoxim methyl
Methoxyfenozide Chlorothalonil Prothioconazole Trifloxystrobin
Methoxyfenozide Chlorothalonil Prothioconazole Benzovindiflupyr
Methoxyfenozide Chlorothalonil Prothioconazole Bixafen
Methoxyfenozide Chlorothalonil Prothioconazole Fluxapyroxad
Methoxyfenozide Chlorothalonil Prothioconazole Isopyrazam
Methoxyfenozide Chlorothalonil Prothioconazole Penthiopyrad
Methoxyfenozide Chlorothalonil Prothioconazole Isoflucypyram
Methoxyfenozide Chlorothalonil Prothioconazole Boscalid
Methoxyfenozide Chlorothalonil Prothioconazole Fluopyram
Methoxyfenozide Metiram Cyproconazole
Methoxyfenozide Metiram Difenoconazole
Methoxyfenozide Metiram Epoxiconazole
Methoxyfenozide Metiram Flutriafol
Methoxyfenozide Metiram Hexaconazole
Methoxyfenozide Metiram Tebuconazole
Methoxyfenozide Metiram Tetraconazole
Methoxyfenozide Metiram Propiconazole
Methoxyfenozide Metiram Prothioconazole
Methoxyfenozide Metiram Azoxystrobin
Methoxyfenozide Metiram Picoxystrobin
Methoxyfenozide Metiram Pyraclostrobin
Methoxyfenozide Metiram Kresoxim methyl
Methoxyfenozide Metiram Trifloxystrobin
Methoxyfenozide Metiram Benzovindiflupyr
Methoxyfenozide Metiram Bixafen
Methoxyfenozide Metiram Fluxapyroxad
Methoxyfenozide Metiram Isopyrazam
Methoxyfenozide Metiram Penthiopyrad
Methoxyfenozide Metiram Isoflucypyram
Methoxyfenozide Metiram Boscalid
Methoxyfenozide Metiram Fluopyram
Methoxyfenozide Metiram Cyproconazole Azoxystrobin
Methoxyfenozide Metiram Cyproconazole Picoxystrobin
Methoxyfenozide Metiram Cyproconazole Pyraclostrobin
Methoxyfenozide Metiram Cyproconazole Kresoxim methyl
Methoxyfenozide Metiram Cyproconazole Trifloxystrobin
Methoxyfenozide Metiram Cyproconazole Benzovindiflupyr
Methoxyfenozide Metiram Cyproconazole Bixafen
Methoxyfenozide Metiram Cyproconazole Fluxapyroxad
Methoxyfenozide Metiram Cyproconazole Isopyrazam
Methoxyfenozide Metiram Cyproconazole Penthiopyrad
Methoxyfenozide Metiram Cyproconazole Isoflucypyram
Methoxyfenozide Metiram Cyproconazole Boscalid
Methoxyfenozide Metiram Cyproconazole Fluopyram
Methoxyfenozide Metiram Difenoconazole Azoxystrobin
Methoxyfenozide Metiram Difenoconazole Picoxystrobin
Methoxyfenozide Metiram Difenoconazole Pyraclostrobin
Methoxyfenozide Metiram Difenoconazole Kresoxim methyl
Methoxyfenozide Metiram Difenoconazole Trifloxystrobin
Methoxyfenozide Metiram Difenoconazole Benzovindiflupyr
Methoxyfenozide Metiram Difenoconazole Bixafen
Methoxyfenozide Metiram Difenoconazole Fluxapyroxad
Methoxyfenozide Metiram Difenoconazole Isopyrazam
Methoxyfenozide Metiram Difenoconazole Penthiopyrad
Methoxyfenozide Metiram Difenoconazole Isoflucypyram
Methoxyfenozide Metiram Difenoconazole Boscalid
Methoxyfenozide Metiram Difenoconazole Fluopyram
Methoxyfenozide Metiram Epoxiconazole Azoxystrobin
Methoxyfenozide Metiram Epoxiconazole Picoxystrobin
Methoxyfenozide Metiram Epoxiconazole Pyraclostrobin
Methoxyfenozide Metiram Epoxiconazole Kresoxim methyl
Methoxyfenozide Metiram Epoxiconazole Trifloxystrobin
Methoxyfenozide Metiram Epoxiconazole Benzovindiflupyr
Methoxyfenozide Metiram Epoxiconazole Bixafen
Methoxyfenozide Metiram Epoxiconazole Fluxapyroxad
Methoxyfenozide Metiram Epoxiconazole Isopyrazam
Methoxyfenozide Metiram Epoxiconazole Penthiopyrad
Methoxyfenozide Metiram Epoxiconazole Isoflucypyram
Methoxyfenozide Metiram Epoxiconazole Boscalid
Methoxyfenozide Metiram Epoxiconazole Fluopyram
Methoxyfenozide Metiram Flutriafol Azoxystrobin
Methoxyfenozide Metiram Flutriafol Picoxystrobin
Methoxyfenozide Metiram Flutriafol Pyraclostrobin
Methoxyfenozide Metiram Flutriafol Kresoxim methyl
Methoxyfenozide Metiram Flutriafol Trifloxystrobin
Methoxyfenozide Metiram Flutriafol Benzovindiflupyr
Methoxyfenozide Metiram Flutriafol Bixafen
Methoxyfenozide Metiram Flutriafol Fluxapyroxad
Methoxyfenozide Metiram Flutriafol Isopyrazam
Methoxyfenozide Metiram Flutriafol Penthiopyrad
Methoxyfenozide Metiram Flutriafol Isoflucypyram
Methoxyfenozide Metiram Flutriafol Boscalid
Methoxyfenozide Metiram Flutriafol Fluopyram
Methoxyfenozide Metiram Hexaconazole Azoxystrobin
Methoxyfenozide Metiram Hexaconazole Picoxystrobin
Methoxyfenozide Metiram Hexaconazole Pyraclostrobin
Methoxyfenozide Metiram Hexaconazole Kresoxim methyl
Methoxyfenozide Metiram Hexaconazole Trifloxystrobin
Methoxyfenozide Metiram Hexaconazole Benzovindiflupyr
Methoxyfenozide Metiram Hexaconazole Bixafen
Methoxyfenozide Metiram Hexaconazole Fluxapyroxad
Methoxyfenozide Metiram Hexaconazole Isopyrazam
Methoxyfenozide Metiram Hexaconazole Penthiopyrad
Methoxyfenozide Metiram Hexaconazole Isoflucypyram
Methoxyfenozide Metiram Hexaconazole Boscalid
Methoxyfenozide Metiram Hexaconazole Fluopyram
Methoxyfenozide Metiram Tebuconazole Azoxystrobin
Methoxyfenozide Metiram Tebuconazole Picoxystrobin
Methoxyfenozide Metiram Tebuconazole Pyraclostrobin
Methoxyfenozide Metiram Tebuconazole Kresoxim methyl
Methoxyfenozide Metiram Tebuconazole Trifloxystrobin
Methoxyfenozide Metiram Tebuconazole Benzovindiflupyr
Methoxyfenozide Metiram Tebuconazole Bixafen
Methoxyfenozide Metiram Tebuconazole Fluxapyroxad
Methoxyfenozide Metiram Tebuconazole Isopyrazam
Methoxyfenozide Metiram Tebuconazole Penthiopyrad
Methoxyfenozide Metiram Tebuconazole Isoflucypyram
Methoxyfenozide Metiram Tebuconazole Boscalid
Methoxyfenozide Metiram Tebuconazole Fluopyram
Methoxyfenozide Metiram Tetraconazole Azoxystrobin
Methoxyfenozide Metiram Tetraconazole Picoxystrobin
Methoxyfenozide Metiram Tetraconazole Pyraclostrobin
Methoxyfenozide Metiram Tetraconazole Kresoxim methyl
Methoxyfenozide Metiram Tetraconazole Trifloxystrobin
Methoxyfenozide Metiram Tetraconazole Benzovindiflupyr
Methoxyfenozide Metiram Tetraconazole Bixafen
Methoxyfenozide Metiram Tetraconazole Fluxapyroxad
Methoxyfenozide Metiram Tetraconazole Isopyrazam
Methoxyfenozide Metiram Tetraconazole Penthiopyrad
Methoxyfenozide Metiram Tetraconazole Isoflucypyram
Methoxyfenozide Metiram Tetraconazole Boscalid
Methoxyfenozide Metiram Tetraconazole Fluopyram
Methoxyfenozide Metiram Propiconazole Azoxystrobin
Methoxyfenozide Metiram Propiconazole Picoxystrobin
Methoxyfenozide Metiram Propiconazole Pyraclostrobin
Methoxyfenozide Metiram Propiconazole Kresoxim methyl
Methoxyfenozide Metiram Propiconazole Trifloxystrobin
Methoxyfenozide Metiram Propiconazole Benzovindiflupyr
Methoxyfenozide Metiram Propiconazole Bixafen
Methoxyfenozide Metiram Propiconazole Fluxapyroxad
Methoxyfenozide Metiram Propiconazole Isopyrazam
Methoxyfenozide Metiram Propiconazole Penthiopyrad
Methoxyfenozide Metiram Propiconazole Isoflucypyram
Methoxyfenozide Metiram Propiconazole Boscalid
Methoxyfenozide Metiram Propiconazole Fluopyram
Methoxyfenozide Metiram Prothioconazole Azoxystrobin
Methoxyfenozide Metiram Prothioconazole Picoxystrobin
Methoxyfenozide Metiram Prothioconazole Pyraclostrobin
Methoxyfenozide Metiram Prothioconazole Kresoxim methyl
Methoxyfenozide Metiram Prothioconazole Trifloxystrobin
Methoxyfenozide Metiram Prothioconazole Benzovindiflupyr
Methoxyfenozide Metiram Prothioconazole Bixafen
Methoxyfenozide Metiram Prothioconazole Fluxapyroxad
Methoxyfenozide Metiram Prothioconazole Isopyrazam
Methoxyfenozide Metiram Prothioconazole Penthiopyrad
Methoxyfenozide Metiram Prothioconazole Isoflucypyram
Methoxyfenozide Metiram Prothioconazole Boscalid
Methoxyfenozide Metiram Prothioconazole Fluopyram

The composition according to the invention can be applied to any and all developmental stages of pests, such as egg, larva, pupa, and adult. The pests may be controlled by contacting the target pest, its food supply, habitat, breeding ground or its locus with a pesticidally effective amount of the inventive mixtures or of compositions comprising the mixtures.
The novel active ingredient composition has very advantageous curative, preventive and systemic fungicidal properties for protecting cultivated plants. As has been mentioned, said active ingredient composition can be used to inhibit or destroy the pathogens that occur on plants or parts of plants (fruit, blossoms, leaves, stems, tubers, roots) of different crops or useful plants, while at the same time those parts of plants which grow later are also protected from attack by such pathogens. Active ingredient composition has the special advantage of being highly active against diseases in the soil that mostly occur in the early stages of plant development.
The synergistic composition of pesticide are used to protect the crops and plants from insect and fungus pests. The lists of the major crops includes genetically modified varieties or hybrid varieties or conventional varieties of Paddy Oryza sativa, Cotton Gossypium spp., Wheat Triticum aestavum, Maize Zea mays, Sugarcane Saccharum officinarum, Soybean Glycin max, Peanut Arachis hypogaea, Sunflower Helianthus annuus, Mustard Brassica juncea, Green gram Vigna radiate, Black gram Vigna mungo, Chickpea Cicer aritinum, Cowpea Vigna unguiculata, Redgram Cajanus cajan, Brinjal Solanum melongena, Cabbage Brassica oleracea var. capitata, Cauliflower Brassica oleracea var. botrytis, Okra Abelmoschus esculentus, Onion Allium cepa L., Tomato Solanum lycopersicun, Potato Solanum tuberosum, Chilly Capsicum annum, Cucumber Cucumis sativus and Melons Cucumis melo, Apple Melus domestica, Banana Musa spp., Citrus groups Citrus spp., Grape Vitis vinifera, Mango Mangifera indica, Papaya Carica papaya, Pomegranate Punica granatum, Tea Camellia sinensis, Coffea Coffea arabica, Cumin Cuminum cyminum etc.
Further the said novel composition can be applied on the seed but are not limited to corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, peanut, buckwheat, beet rapeseed, sunflower, sugar cane, tobacco, etc.
The said synergistic composition can be applied on seed treatment of the vegetables and vegetables crops but not limited to solanaceous vegetables such as eggplant, tomato, pimento, pepper, potato, etc., cucurbit vegetables such as cucumber, pumpkin, zucchini, water melon, melon, squash, etc., cruciferous vegetables such as radish, white turnip, horseradish, kohlrabi, C hinese cabbage, cabbage, leaf mustard, broccoli, cauliflower, etc., asteraceous vegetables such as burdock, crown daisy, artichoke, lettuce, etc, liliaceous vegetables such as green onion, onion, garlic, and asparagus, ammiaceous vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceous vegetables such as spinach, Swiss chard, etc., lamiaceous vegetables such as P erilla frutescens, mint, basil, etc, strawberry, sweet potato, Dioscorea japonica, colocasia, etc., flowers, foliage plants, turf grasses, fruits: , pome fruits such apple, pear, quince, etc, stone fleshy fruits such as peach, plum, nectarine, P runus mume, cherry fruit, apricot prune, etc., citrus fruits such as orange, lemon, rime, grapefruit, etc., nuts such as chestnuts, walnuts, hazelnuts, almond, pistachio, cashew nuts, macadamia nuts, etc. berries such as blueberry, cranberry, blackberry, raspberry, etc., grape, kaki fruit olive, plum, banana, coffee, i¾ date palm, coconuts, etc. , trees other than fruit trees; tea, mulberry, flowering plant, trees such as ash, birch, dogwood, Eucalyptus, Ginkgo biloba, lilac, maple, Quercus, poplar, J udas tree, Liquidambar formosana, plane tree, zelkova, J apanese arborvitae, fir wood, hemlock, juniper, Pinus, Picea, and Taxus cuspidate, etc.
The synergistic combination of the present invention used to control the insects-pests belongs to the order Hemiptera, for example, rice leafhopper Nephotettix nigropictus, rice brown plant hopper Nilaparvata lugen, rice white backed plant hopper, Apple Mealy bug Phenococcus aceris, bean aphid Aphis fabae, black citrus aphid Toxoptera aurantii, citrus black scale Saissetia oleae, cabbage aphid Brevicoryne brassicae, Lipaphis erysimi, citrus red scale Aonidiella aurantii, yellow scale Aonidiella citrine, citrus mealybug Planococcus citri, corn leaf aphid Rhopalosiphum maidis, cotton aphid Aphis gossypii, cotton jassid Amrasca biguttula biguttla, cotton mealy bug Planococcus spp. And Pseudococcus spp., cotton stainer Dysdercus suturellus, cotton whitefly Bemisia tabaci, cowpea aphid Aphis crassivora, grain aphid Sitobion avenae, golden glow aphid Uroleucon spp., grape mealybug Pseudococcus maritimus, green peach aphid Myzus persicae, greenhouse whitefly Trialeurodes vaporariorum, papaya mealy bug Pracoccus marginatus, pea aphid Acyrthosiphon pisum, sugarcane mealybug Saccharicoccus sacchari, potato aphid Myzus persicae, potato leaf hopper Empoasca fabae, cotton whitefly Bemisia tabaci, tarnished plant bug Lygus lineolaris, wooly apple aphid Eriosoma lanigerum, mango hopper Amritodus atkinsoni, Idioscopus spp. ; order Lepidoptera, army worm Mythimna unipuncta, asiatic rice borer Chilo suppressalis, bean pod borer Maruca vitrata, beet armyworm Spodoptera exigua, black cutworm Agrotis ipsilon, bollworm Helicoverpa armigera , cabbage looper Trichoplusia ni, codling moth Cydia pomonella, croton caterpillar Achea janata, diamond backmoth Plutella xylostella, cabbage worm Pieris rapae, pink bollworm Pectinophora gossypiella, sugarcane borer Diatraea saccharalis, tobacco budworm Heliothis virescens, tomato fruitworm Helicoverpa zea, velvet bean caterpillar Anticarsia gemmatalis, yellow stem borer Scirpophaga incertulas, spotted bollworm Earias vittella, rice leaffolder Cnaphalocrocis medinalis, pink stem borer Sesamia spp., tobacco leafeating caterpillar Spodoptera litura; brinjal fruit and shoot borer Leucinodes orbonalis, bean pod borer Maruca vitrata, Maruca testulalis, armyworm Mythimna separata, cotton pinkbollworm Pectinophora gossypiella, citrus leafminer Phyllocnistis citrella, cabbage butterfly Pieris bras-sicae, diamond backmoth Plutella xylostella, paddy stem borer Scirpophaga excerptallis, Scirpophaga incertulas, Scirpophaga innotata, wheat stem borer Sesamia inferens, Sitotroga cerealella, Spilosoma obliqua, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Trichoplusia ni, Tryporyza novella, Tuta absoluta.
from the order Coleoptera, for example, apple twig borer Amphicerus spp., corn root worm Diabrotica virgifera, cucumber beetle diabrotica balteata, boll weevil Anthonomus grandis, grape flea beetle Altica chalybea, grape root worm Fidia viticola, grape trunk borer Clytoleptus albofasciatus, radish flea beetle Phyllotreta armoraciae, maize weevil Sitophilus zeamais, northern corn rootworm Diabrotica barberi, rice water weevil Lissorhoptrus oryzophilus, Anthonomus grandis, Bruchus lentis, Diabrotica semipunctata, Diabrotica virgifera, Dicladispa armigera, Epila-chna varivestis, various species of white grubs are Holotrichia bicolor, Holotrichia consanguinea, Holotrichia serrata, Leptinotarsa decemlineata, Phyllotreta chrysocephala, Popillia japonica etc; from the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp.; from the order Thysanoptera, for example, Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis; termites (Isoptera), e.g. Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Leucotermes flavipes, Microtermes obesi, Odontotermes obesus, Reticulitermes flavipes, Termes natalensis; from the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp., from the order Hymenoptera, for example, Solenopsis spp. ; from the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp., from the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Polyphagotarsonemus latus, Tarsonemus spp., Tetranychus urticae, Tetranychus cinnabarinus.
The compositions according to the invention have very good fungicidal properties and can be employed for controlling phytopathogenic fungi such as Ascomycetes, Basidiomycetes, Chytridiomycetes, Deuteromycetes, Oomycetes, Plasmodiophoromycetes, Zygomycetes, and the like.
Examples which may be mentioned, but not by limitation, are some pathogens of fungal diseases which come under the above generic terms:
Diseases caused by pathogens causing powdery mildew such as, for example, Blumeria species such as, for example, Blumeria graminis; Podosphaera species such as, for example, Podosphaera leucotricha; Oidium species such as, for example Oidium mangiferae, Sphaerotheca species such as, for example, Sphaerotheca fuliginea; Uncinula species such as, for example, Uncinula necator; Leveillula species such as, for example Leveillula taurica, Erysiphe species such as for example Erysiphe polygoni, diseases caused by pathogens of rust diseases such as, for example, Gymnosporangium species such as, for example, Gymnosporangium sabinae, Hemileia species such as, for example, Hemileia vastatrix; Phakopsora species such as, for example, Phakopsora pachyrhizi and Phakopsora meibomiae; Puccinia species such as, for example, Puccinia graminis, Puccinia recondita or Puccinia triticina, Puccinia striiformis; Uromyces species such as, for example, Uromyces phaseoli; diseases caused by pathogens of smut diseases such as, for example, Sporisorium species such as , for example, Sporisorium scitamineum; Ustilago species such as, for example Ustilago maydis, Tilletia species such as for example Tilletia tritici, Ustilaginoidea species such as , for example Ustilaginoidea virens, diseases caused by pathogens of ergot diseases such as, for example Claviceps species, Claviceps purpurea; diseases caused by pathogens from the group of the Oomycetes such as, for example, Bremia species such as, for example, Bremia lactucae; Peronospora species such as, for example, Peronospora pisi or P. brassicae; Phytophthora species such as, for example, Phytophthora infestans; Plasmopara species such as, for example, Plasmopara viticola; Pseudoperonospora species such as, for example, Pseudoperonospora humuli or Pseudoperonospora cubensis; Pythium species such as, for example, Pythium ultimum; leaf spot diseases and leaf wilt caused by, for example, Alternaria species such as, for example, Alternaria solani; Cercospora species such as, for example, Cercospora arachidicola; Cladiosporum species such as, for example, Cladiosporium cucumerinum; Cochliobolus species such as, for example, Cochliobolus sativus (conidial form: Drechslera, syn: Helminthosporium);
Colletotrichum species such as, for example, Colletotrichum lindemuthanium; Cycloconium species such as, for example, Cycloconium oleaginum; Diaporthe species such as, for example, Diaporthe citri;
Elsinoe species such as, for example, Elsinoe fawcettii; Gloeosporium species such as, for example, Gloeosporium laeticolor; Glomerella species such as, for example, Glomerella cingulata; Guignardia species such as, for example, Guignardia bidwelli; Leptosphaeria species such as, for example, Leptosphaeria maculans; Magnaporthe species such as, for example, Magnaporthe grisea;
Mycosphaerella species such as, for example, Mycosphaerella graminicola; Phaeosphaeria species such as, for example, Phaeosphaeria nodorum; Pyrenophora species such as, for example, Pyrenophora teres;
Ramularia species such as, for example, Ramularia collo-cygni; Rhynchosporium species such as, for example, Rhynchosporium secalis; Septoria species such as, for example, Septoria apii;
Typhula species such as, for example, Typhula incarnata; Venturia species such as, for example, Venturia inaequalis; root and stalk diseases, caused by, for example, Corticium species such as, for example, Corticium graminearum; Fusarium species such as, for example, Fusarium oxysporum;
Gaeumannomyces species such as, for example, Gaeumannomyces graminis; Rhizoctonia species such as, for example, Rhizoctonia solani; Tapesia species such as, for example, Tapesia acuformis;
Thielaviopsis species such as, for example, Thielaviopsis basicola; ear and panicle diseases (including maize cobs), caused by, for example, Alternaria species such as, for example, Alternaria spp.;
Aspergillus species such as, for example, Aspergillus flavus; Cladosporium species such as, for example, Cladosporium spp.; Claviceps species such as, for example, Claviceps purpurea;
Fusarium species such as, for example, Fusarium culmorum; Gibberella species such as, for example, Gibberella zeae; Monographella species such as, for example, Monographella nivalis;
diseases caused by smuts such as, for example, Sphacelotheca species such as, for example, Sphacelotheca reiliana; Tilletia species such as, for example, Tilletia caries; Urocystis species such as, for example, Urocystis occulta; Ustilago species such as, for example, Ustilago nuda;
Fruit rot caused by, for example, Aspergillus species such as, for example, Aspergillus flavus;
Botrytis species such as, for example, Botrytis cinerea; Penicillium species such as, for example, Penicillium expansum; Sclerotinia species such as, for example, Sclerotinia sclerotiorum;
Verticilium species such as, for example, Verticilium alboatrum; seed- and soil-borne rots and wilts, and seedling diseases, caused by, for example, Fusarium species such as, for example, Fusarium culmorum; Phytophthora species such as, for example, Phytophthora cactorum; Pythium species such as, for example, Pythium ultimum; Rhizoctonia species such as, for example, Rhizoctonia solani;
Sclerotium species such as, for example, Sclerotium rolfsii; cankers, galls and witches' broom diseases, caused by, for example, Nectria species such as, for example, Nectria galligena; wilts caused by, for example, Monilinia species such as, for example, Monilinia laxa; deformations of leaves, flowers and fruits, caused by, for example, Taphrina species such as, for example, Taphrina deformans; degenerative diseases of woody species, caused by, for example, Esca species such as, for example, Phaemoniella clamydospora; flower and seed diseases, caused by, for example, Botrytis species such as, for example, Botrytis cinerea; diseases of plant tubers caused by, for example, Rhizoctonia species such as, for example, Rhizoctonia solani; diseases caused by bacterial pathogens such as, for example, Xanthomonas species such as, for example, Xanthomonas campestris pv. oryzae; Pseudomonas species such as, for example, Pseudomonas syringae pv. lachrymans; Erwinia species such as, for example, Erwinia amylovora.
The compositions according to the present invention is effective for the following plant diseases:
Diseases of Soybeans : Alternaria leaf spot Alternaria spp. Anthracnose Colletotrichum truncatum, Black root rot Thielaviopsis basicola,Brown spot Septoria glycines,Brown stem rot Cephalosporium gregat, Charcoal rot Macrophomina phaseolina, Choanephora leaf blight Choanephora infundibulifera,Damping-off Rhizoctonia solani, Pythium aphanidermatum,P. ultimum, Downy mildew Peronospora manshurica, Drechslera blight Drechslera glycines, Frogeye leaf spot Cercospora sojina, Fusarium root rot Fusarium spp., Phomopsis seed decay Phomopsis spp., Phytophthora root and stem rot Phytophthora sojae, Pod and stem blight Diaporthe phaseolorum, Powdery mildew Microsphaera diffusa, Pythium rot, Rhizoctonia aerial blight Rhizoctonia solani, Rhioctonia root and stem rot Rhizoctonia solani, Rust Phakopsora pachyrhizi, Sclerotinia stem rot Sclerotinia sclerotiorum, Southern blight (damping-off and stem rot) = Sclerotium blight Sclerotium rolfsii, Stemphylium leaf blight Stemphylium botryosum, Sudden death syndrome Fusarium solani, Asian soybean rust Phakopsora pachyrhizi and Phakopsora meibomiae.
Diseases of Peanut : Alternaria leaf blight Alternaria tenuissima, Alternaria leaf spot Alternaria arachidis,Alternaria alternate, Anthracnose Colletotrichum arachidis,Aspergillus crown rot Aspergillus niger, Botrytis blight Botrytis cinerea, Charcoal rot and Macrophomina leaf spot Macrophomina phaseolina,Choanephora leaf spot Choanephora spp. Collar rot Diplodia gossypina, Colletotrichum leaf spot Colletotrichum gloeosporioides,Cylindrocladium black rot & leaf spot Cylindrocladium crotalariae, Damping-off, Aspergillus flavus, A. niger, Fusarium spp., Pythium spp., Rhizoctonia spp., Rhizopus spp., Drechslera leaf spot Bipolaris spicifera=Drechslera spicifera,Fusarium peg and root rot Fusarium spp., Fusarium wilt Fusarium oxysporum, Leaf spot, early Cercospora arachidicola (teleomorph: Mycosphaerella arachidis), Leaf spot, late Phaeoisariopsis personata=Cercosporidium personatum, Myrothecium leaf blight Myrothecium roridum, Peanut Smut Thecaphora frezii, Phoma leaf blight Phoma microspora, Phomopsis foliar blight Phomopsis phaseoli, Phomopsis leaf spot, Pod rot (pod breakdown) Fusarium equiseti, F. solani, Pythium myriotylum, Rhizoctonia solani, Powdery mildew Oidium arachidis, Pythium peg and root rot, Pythium myriotylum,P. aphanidermatum, P. debaryanum, P. irregulare, P. ultimum, Pythium wilt Pythium myriotylum, Rhizoctonia foliar blight, peg and root rot Rhizoctonia solani, Rust Puccinia arachidis, Sclerotinia blight Sclerotinia minor, S. sclerotiorum, Stem rot (southern blight) Sclerotium rolfsii, Verticillium wilt Verticillium albo-atrum, V. dahliae, Web blotch (net blotch) Phoma arachidicola= Ascochyta adzamethica, Yellow mold Aspergillus flavus, A. parasiticus.
Diseases of Sunflower : Alternaria leaf blight, stem spot and head rot Alternaria alternate, A. tenuis, A. helianthi, Botrytis head rot (gray mold) Botrytis cinerea, Charcoal rot Macrophomina phaseolina= Sclerotium bataticola=Rhizoctonia bataticola, Downy mildew Plasmopara halstedii, Fusarium stalk rot Fusarium equiseti, F. solani, Fusarium tabacinum, Fusarium wilt Fusarium moniliforme, F. oxysporum,Myrothecium leaf and stem spot Myrothecium roridum,Phoma black stem Phoma macdonaldii, Phomopsis brown stem canker Phomopsis spp., P. helianthi, Phymatotrichum root rot (cotton root rot) Phymatotrichopsis omnivora=Phymatotrichum omnivorum, Phytophthora stem rot Phytophthora spp., Powdery mildew Erysiphe cichoracearum (anamorph: Oidium asteris-punicei), Leveillula compositarum, L. taurica (anamorph: Oidiopsis sicula), Sphaerotheca fuliginea, Pythium seedling blight and root rot Pythium spp., Rhizoctonia seedling blight Rhizoctonia solani, Rhizopus head rot Rhizopus arrhizus, R. nodosus, R. microspores, R. stolonifer, R. nigricans, Rust Puccinia helianthi, Uromyces junci, Sclerotinia basal stalk rot and wilt, mid-stalk rot, head rot Sclerotinia sclerotiorum, Sclerotinia minor, Sclerotium rolfsii, Septoria leaf spot Septoria helianthi , Verticillium wilt Verticillium albo-atrum, White rust, Albugo tragopogonis, Yellow rust Coleosporium helianthi (Schwein.)
Disease in rice: Blast (Magna porthe grisea), Helminthosporium leaf spot (C ochliobolus miyabeanus), sheath blight (R hizoctonia solani) , and bakanae i¾ disease (G ibberella fujikuroi).
Diseases in wheat: powdery mildew (E rysiphe graminis), F usariuin head blight (F usarium graminearum, F. avenacerum, F. culmorum, Microdochium nivale) , rust (P uccinia striiformis, P. graminis, P. recondita) , pink snow mold (Micronectriella †3a nivale), Typhula snow blight (Typhula sp . ) , loose smut (Ustilago tritici) , bunt (Tilletia caries) , eyespot (Pseudocercosporella herpotrichoides) , leaf blotch (Mycosphaerella graminicola) , glume blotch (S tagonospora nodorum) , septoria, and yellow spot (Pyrenophora tritici-repentis).
Diseases of barley: powdery mildew (E rysiphe graminis), F usarium head blight ¾ (F usarium graminearum, F. avenacerum, F. culmorum, Microdochium nivale), rust (P uccinia striiformis, P. graminis, P. hordei), loose smut (Ustilago nuda), scald (R hynchosporium secalis), net blotch (Pyrenophora teres), spot blotch (C ochliobolus sativus), leaf stripe (Pyrenophora graminea), and R hizoctonia damping-off (R hizoctonia solani).
Diseases in corn: smut (Ustilago maydis), brown spot (Cochliobolus heterostrophus), copper spot (G loeocercospora sorghi), southern rust (P uccinia polysora), gray leaf spot (C ercospora zeae-maydis), white spot (P haeosphaeria mydis and/or Pantoea ananatis) and R hizoctonia damping-off (R hizoctonia solani).
Diseases of citrus: melanose (Diaporthe citri), scab (E lsinoe fawcetti), penicillium rot (Penicillium digitatum, P.italicum), and brown rot (P hytophthora parasitica, P hytophthora citrophthora).
Diseases of apple: blossom blight (Monilinia mali), canker (Valsa ceratosperma) , powdery mildew (P odosphaera leucotricha), Alternaria leaf spot (Alternaria alternata apple pathotype) , scab (Venturia inaequalis), powdery mildew, bitter rot (C olletotrichum acutatum) , crown rot (P hytophtora cactorum) , blotch (Diplocarpon mali) , and ring rot (Botryosphaeria berengeriana).
Diseases of pear: scab (Venturia nashicola, V. pirina), powdery mildew, black spot (Alternaria alternata J apanese pear pathotype), rust (Gymnosporangium haraeanum), and phytophthora fruit rot (P hytophtora cactorum).
Diseases of peach: brown rot (Monilinia fructicola), powdery mildew, scab (C ladosporium carpophilum), and phomopsis rot (P homopsis sp.).
Diseases of grape: anthracnose (E lsinoe ampelina), ripe rot (G lomerella cingulata), powdery mildew (Uncinula necator), rust (P hakopsora ampelopsidis), black rot (G uignardia bidwellii), botrytis, and downy mildew (P lasmopara viticola).
Diseases ofj apanese persimmon: anthracnose (G loeosporium kaki), and leaf spot (C ercospora kaki, Mycosphaerella nawae).
Diseases of gourd: anthracnose (C olletotrichum lagenarium), powdery mildew (S phaerotheca fuliginea), gummy stem blight (Mycosphaerella melonis), F usarium 3a wilt (Fusarium oxysporum), downy mildew (Pseudoperonospora cubensis), P hytophthora rot (P hytophthora sp.), and damping-off (Pythium sp.).
Diseases of tomato: early blight (Alternaria solani), leaf mold (C ladosporium fulvum), and late blight (P hytophthora infestans).
Diseases of eggplant: brown spot (P homopsis vexans), and powdery mildew (E rysiphe cichoracearum) Diseases of cruciferous vegetables: Alternaria leaf spot (Alternaria japonica), white spot (C ercosporella brassicae), clubroot (P lasmodiophora brassicae), and downy mildew (P eronospora parasitica).
Diseases of onion: rust (P uccinia allii), and downy mildew (Peronospora destructor).
Diseases of kidney bean: anthracnose (C olletotrichum lindemthianum). Diseases of peanut: leaf spot (Cercospora personata), brown leaf spot (C ercospora arachidicola) and southern blight (S clerotium rolfsii).
Diseases of garden pea: powdery mildew (E rysiphe pisi), and root rot (F usarium solani f. sp. pisi).
Diseases of potato: early blight (Alternaria solani), late blight (P hytophthora infestans), pink rot (P hytophthora erythroseptica), and powdery scab (S pongospora subterranean f. sp. subterranea).
Diseases of strawberry: powdery mildew (S phaerotheca humuli), and anthracnose 3a (G lomerella cingulata).
Diseases of tea: net blister blight (Exobasidium reticulatum), white scab (E lsinoe leucospila), gray blight (Pestalotiopsis sp.), and anthracnose (Colletotrichum theae- sinensis).
Diseases of tobacco: brown spot (Alternaria longipes), powdery mildew (E rysiphe cichoracearum), anthracnose (C olletotrichum tabacum), downy mildew (P eronospora tabacina), and black shank (P hytophthora nicotianae).
Formulation of the present invention can be in any of the formulations selected from Capsule suspension (CS), Dispersible concentrate (DC), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion for seed treatment (ES), Emulsion, oil in water (EW), Flowable suspension/concentrate for seed treatment (FS), Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), Solution for seed treatment (LS), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (= flowable concentrate) (SC), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Water soluble powder (SP), Water dispersible granule (WG or WDG), Wettable powder (WP), Water dispersible powder for slurry treatment (WS), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), A mixed formulation of CS and EW (ZW).
One or more of the active ingredients is encapsulated for various purposes, such as to increase the residual biological activity, or to reduce the acute toxicity, or to obtain a physical or chemically stable water-based formulation. The purpose determines whether the “free” active ingredient and the “release rate” are relevant properties of a specific product.
The composition of the present invention in addition to bioactive amounts of active ingredients further comprises inactive excipients including but not limited to dispersant, anti-freezing agent, anti-foam agent, wetting agent, suspension aid, antimicrobial agent, thickener, quick coating agent or sticking agents (also referred to as “stickers” or “binders”) and buffering agent.
A dispersant is a substance which adsorbs onto the surface of particles and helps to preserve the state of dispersion of the particles and prevents them from re-aggregating. Dispersants are added to agrochemical formulations to facilitate dispersion and suspension during manufacture, and to ensure the particles re-disperse into water in a spray tank. They are widely used in wettable powders, suspension concentrates and water-dispersible granules. Surfactants that are used as dispersants have the ability to adsorb strongly onto a particle surface and provide a charged or steric barrier to reaggregation of particles. The most commonly used surfactants are anionic, non-ionic, or mixtures of the two types. For wettable powder formulations, the most common dispersants are sodium lingo sulphonates. For suspension concentrates, very good adsorption and stabilization are obtained using polyelectrolytes, such as sodium naphthalene sulphonate formaldehyde condensates. Tristyrylphenolethoxylate phosphate esters are also used. Nonionics such as alkyl aryl ethylene oxide condensates and EO-PO block copolymers are sometimes combined with anionics as dispersants for suspension concentrates. In recent years, new types of very high molecular weight polymeric surfactants have been developed as dispersants. These have very long hydrophobic ‘backbones’ and a large number of ethylene oxide chains forming the ‘teeth’ of a ‘comb’ surfactant. These high molecular weight polymers can give very good long-term stability to suspension concentrates because the hydrophobic backbones have many anchoring points onto the particle surfaces. Examples of dispersants used herein include but not limited to sodium lingo sulphonates; sodium naphthalene sulphonate formaldehyde condensates; tristyryl phenol ethoxylate phosphate esters; aliphatic alcohol ethoxylates; alky ethoxylates; EO-PO block copolymers; and graft copolymers or mixtures thereof.
Anti-freezing agent as used herein can be selected from the group consisting of polyethylene glycols, methoxy polyethylene glycols, polypropylene glycols, polybutylene glycols, glycerin and ethylene glycol. Water-based formulations often cause foam during mixing operations in production. In order to reduce the tendency to foam, anti-foam agents are often added either during the production stage or before filling into bottles. Generally, there are two types of antifoam agents, namely silicones and non-silicones. Silicones are usually aqueous emulsions of dimethyl poly siloxane while the non-silicone anti-foam agents are water- insoluble oils, such as octanol and nonanol, or silica. In both cases, the function of the anti-foam agent is to displace the surfactant from the air-water interface.
A wetting agent is a substance that when added to a liquid increases the spreading or penetration power of the liquid by reducing the interfacial tension between the liquid and the surface on which it is spreading. Wetting agents are used for two main functions in agrochemical formulations: during processing and manufacture to increase the rate of wetting of powders in water to make concentrates for soluble liquids or suspension concentrates; and during mixing of a product with water in a spray tank or other vessel to reduce the wetting time of wettable powders and to improve the penetration of water into water-dispersible granules. Examples of wetting agents used in wettable powder, suspension concentrate, and water-dispersible granule formulations include but not limited to sodium lauryl sulphate; sodium dioctyl sulpho succinate; alkyl phenol ethoxylates; and aliphatic alcohol ethoxylates or mixtures thereof.
Suspension aid in the present description denotes a natural or synthetic, organic or inorganic material with which the active substance is combined in order to facilitate its application to the plant, to the seeds or to the soil. This carrier is hence generally inert, and it must be agriculturally acceptable, in particular to the plant being treated. The carrier may be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, and the like or mixtures thereof) or liquid (water, alcohols, ketones, petroleum fractions, aromatic or paraffinic hydrocarbons, chlorinated hydrocarbons, liquefied gases, and the like or mixtures thereof).
Biocides / Microorganisms cause spoilage of formulated products. Therefore antimicrobial agents are used to eliminate or reduce their effect. Examples of such agents include, but are not limited to: propionic acid and its sodium salt; sorbic acid and its sodium or potassium salts; benzoic acid and its sodium salt; p-hydroxy benzoic acid sodium salt; methyl p-hydroxy benzoate; and biocide such as sodium benzoate, 1,2- benzisothiazoline-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4- isothiazolin-3-one, potassium sorbate, para hydroxy benzoates or mixtures thereof.
Thickeners or gelling agents are used mainly in the formulation of suspension concentrates, emulsions and suspoemulsions to modify the rheology or flow properties of the liquid and to prevent separation and settling of the dispersed particles or droplets. Thickening, gelling, and anti-settling agents generally fall into two categories, namely water-insoluble particulates and water-soluble polymers. It is possible to produce suspension concentrate formulations using clays and silicas. Examples of these types of materials, include, but are limited to, montmorillonite, e.g. bentonite; magnesium aluminum silicate; and attapulgite. Water-soluble polysaccharides have been used as thickening-gelling agents for many years. The types of polysaccharides most commonly used are natural extracts of seeds and seaweeds are synthetic derivatives of cellulose or mixtures thereof. Examples of these types of materials include, but are not limited to, guar gum; locust bean gum; carrageenam; xanthan gum; alginates; methyl cellulose; sodium carboxymethyl cellulose (SCMC); hydroxyethyl cellulose (HEC) or mixtures thereof. Other types of anti-settling agents are based on modified starches, polyacrylates, polyvinyl alcohol and polyethylene oxide or mixtures.
The quick coating agent can be a conventionally available sticker, for example polyesters, polyamides, poly- carbonates, polyurea and polyurethanes, acrylate polymers and copolymers, styrene copolymers, butadiene copolymers, polysaccharides such as starch and cellulose derivatives, vinyl alcohol, vinyl acetate and vinyl pyrrolidone polymers and copolymers, polyethers, epoxy, phenolic and melamine resins, polyolefins and define copolymers and mixtures thereof. Examples of preferred polymers are acrylate polymers such as poly(methacrylate), poly(ethyl methacrylate), poly(methyl methacrylate), acrylate copoylmers and styrene-acrylic copolymers as defined herein below, poly(styrene-co maleic anhydride), cellulosic polymers such as ethyl cellulose, cellulose acetate, cellulose acetatebutyrate, acetylated mono, di, and triglycerides, poly(vinyl pyrrolidone), vinyl acetate polymers and copolymers, poly(alkylene glycol), styrene butadiene copolymers, poly(ortho esters), alkyd resins, and mixtures of two or more of these.
Polymers that are biodegradable are also useful in the present invention. As used herein, a polymer is biodegradable if is not water soluble, but is degraded over a period of several weeks when placed in an application environment. Examples of biodegradable polymers that are useful in the present invention include biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, poly(lactic acid-glycolic acid) copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch ester aliphatic polyester blends, modified corn starch, poly capro lactone, poly(namylmethacrylate), wood rosin, poly anhydrides, poly vinyl alcohol, poly hydroxyl butyrate valerate, biodegradable aliphatic polyesters, and poly hydroxyl butyrate or mixtures thereof.
Buffering agent as used herein is selected from group consisting of calcium hydroxyapatite, Potassium Dihydrogen Phosphate, Sodium Hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase and magnesium hydroxide.
The solvent for the formulation of the present invention may include water, water soluble alcohols and dihydroxy alcohol ethers. The water-soluble alcohol which can be used in the present invention may be lower alcohols or water-soluble macromolecular alcohols. The term "lower alcohol", as used herein, represents an alcohol having 1-4 carbon atoms, such as methanol, ethanol, n-propanol, isopropanol, n-butanol, tertbutanol, etc. Macromolecular alcohol is not limited, as long as it may be dissolved in water in a suitable amount range, e.g., polyethylene glycol, sorbitol, glucitol, etc. The examples of suitable dihydroxy alcohol ethers used in the present invention may be dihydroxy alcohol alkyl ethers or dihydroxy alcohol aryl ethers. The examples of dihydroxy alcohol alkyl ether include ethylene glycol methyl ether, diethylene glycol methyl ether, propylene glycol methyl ether, dipropylene glycol methyl ether, ethylene glycol ethyl ether, diethylene glycol ethyl ether, propylene glycol ethyl ether, dipropylene glycol ethyl ether, etc. The examples of dihydroxy alcohol aryl ethers include ethylene glycol phenyl ether, diethylene glycol phenyl ether, propylene glycol phenyl ether, dipropylene glycol phenyl ether, and the like. Any of the above mentioned solvent can be used either alone or in combination thereof.
The process for preparing the present novel synergistic composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However all such variation and modification is still covered by the scope of present invention.
In further aspect the present invention relates to the synergistic pesticidal composition comprising bioactive amounts of (A) is 5 to 25 % w/w of the composition; (B) is 20 to 60% w/w of the composition; and (C) is 2 to 20 %w/w of the composition.

Active Ingredients Compound
A Compound
B Compound
C
Examples Insecticide
Diacylhydrazines group Fungicide
multisite action Fungicide
% of Active Ingredient
5 to 25 %w/w
20 to 60 %w/w
2 to 20 %w/w
The composition of the present invention in addition to bioactive amounts of active ingredients further comprises inactive excipients including but not limited to dispersant or dispersing agent, anti-freezing agent, anti-foam agent, wetting agent, suspension aid, disintegrating agent, thickener, preservative and carrier.
A wetting agent is a substance that when added to a liquid increases the spreading or penetration power of the liquid by reducing the interfacial tension between the liquid and the surface on which it is spreading. Wetting agents are used for two main functions in agrochemical formulations: during processing and manufacture to increase the rate of wetting of powders in water to make concentrates for soluble liquids or suspension concentrates; and during mixing of a product with water in a spray tank or other vessel to reduce the wetting time of wettable powders and to improve the penetration of water into water-dispersible granules.
Examples of wetting agent used herein for SC (Suspension concentrate) formulation include but not limited to ethylene oxide/propylene oxide block copolymer, polyarylphenyl ether phosphate, ethoxylated fatty alcohol, sodium dioctyl sulfosuccinate, sodium lauryl sulfate and sodium dodecyl benzene sulfonate, alkyl diphenyl sulfonates, sodium isopropyl naphthalene sulfonate, alkylnaphthalene sulfonate, Organosilicone surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, 10 mole ethylene oxide adduct of octylphenol, may or may not be in modified form, may be liquid or powder form or mixture thereof.
Examples of wetting agent used herein for WG (Wettable Granule), WDG (Water Dispersible Granule) formulation includes but not limited to sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridexyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkyaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and diisopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, Organosilicone surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, 10 mole ethylene oxide adduct of octylphenol, may or may not be in modified form, may be powder form.
A dispersant or a dispersing agent is a substance which adsorbs onto the surface of particles and helps to preserve the state of dispersion of the particles and prevents them from re-aggregating. Dispersants are added to agrochemical formulations to facilitate dispersion and suspension during manufacture, and to ensure the particles re-disperse into water in a spray tank. They are widely used in wettable powders, suspension concentrates and water-dispersible granules. Surfactants that are used as dispersants have the ability to adsorb strongly onto a particle surface and provide a charged or steric barrier to re-aggregation of particles. The most commonly used surfactants are anionic, non-ionic, or mixtures of the two types. For wettable powder formulations, the most common dispersants are sodium lingo sulphonates. In recent years, new types of very high molecular weight polymeric surfactants have been developed as dispersants. These have very long hydrophobic ‘backbones’ and a large number of ethylene oxide chains forming the ‘teeth’ of a ‘comb’ surfactant. These high molecular weight polymers can give very good long-term stability to suspension concentrates because the hydrophobic backbones have many anchoring points onto the particle surfaces.
Examples of dispersants or dispersing agent used herein for SC (Suspension concentrate) formulation include but not limited to alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium ploycarboxylate,EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide.
Examples of dispersants or dispersing agent used herein for WG (Wettable Granule), WDG (Water Dispersible Granule) formulation include but not limited to naphthalene sulfonic acid, sodium salt condensated with formaldehyde, polyalcoxylated alkylphenol, naphthalenesulfonic acid formaldehyde condensate, methylnaphtaline-formaldehyde-condensate sodium salt, napthalene condensates, lignosulfonates, polyacrylates and phosphate esters, calcium lignosulfonate,lignin sulfonate sodium salt.
Antifoaming agent for the present formulation is selected from various compounds and selectively used according to the formulation. Generally, there are two types of antifoam agents, namely silicones and non-silicones. Silicones are usually aqueous emulsions of dimethyl poly siloxane while the non-silicone anti-foam agents are water- insoluble oils, such as octanol and nonanol, or silica. In both cases, the function of the anti-foam agent is to displace the surfactant from the air-water interface.
Examples of Antifoaming agent used herein for SC (Suspension concentrate) formulation, include but not limited to silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethylsiloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane.
Examples of Antifoaming agent used herein for WG (Wettable Granule) formulation includes but not limited to polydimethylsiloxane and sodium alkylate.
Anti-freezing agent for the present formulation is selected from various compounds and selectively used according to the formulation.
Examples of Anti-freezing agent used herein for SC (Suspension concentrate) formulation include but not limited to ethylene glycol, propane diols, glycerine or the urea, glycol (monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol), glycerine, urea, magnesium sulfate heptahydrate, sodium chloride.
Disintegrating agent used herein for the WG (Wettable Granule) formulation is selected from citric acid, succinic acid or the sodium bicarbonate.
Preservative used herein for the SC (Suspension concentrate) formulation include but not limited to 1,2-benzisothiazolin-3(2H)-one, sodium salt, Sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, Formaldehyde, Sodium o-phenylphenate, 5-chloro-2-methyl-4-isothiazolin-3-one & 2-methyl-4-isothiazolin-3-one.
Thickeners or gelling agents are used mainly in the formulation of suspension concentrates, emulsions and suspoemulsions to modify the rheology or flow properties of the liquid and to prevent separation and settling of the dispersed particles or droplets. Thickening, gelling, and anti-settling agents generally fall into two categories, namely water-insoluble particulates and water-soluble polymers.
Examples of thickeners used herein for SC (Suspension concentrate) formulation include but not limited to xanthan gum, PVK, carboxymethylcelluloses, polyvinyl alcohols,gelatin, sodium carboxymethylcellulose, hydroxyethylcellulose, sodium polyacrylate, modified starch;
Suspension aid or the suspending agent in the present description denotes a natural or synthetic, organic or inorganic material with which the active substance is combined in order to facilitate its application to the plant, to the seeds or to the soil. This carrier is hence generally inert, and it must be agriculturally acceptable, in particular to the plant being treated. The carrier may be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, and the like or mixtures thereof) or liquid (water, alcohols, ketones, petroleum fractions, aromatic or paraffinic hydrocarbons, chlorinated hydrocarbons, liquefied gases, and the like or mixtures thereof).
Examples of suspending agent used herein for SC (Suspension concentrate) formulation include but not limited to Aluminum Magnesium Silicate, Bentonite clay, Silica, Attapulgite clay.
Carrier for the present formulation is selected from selected from various compounds and selectively used according to the formulation. Certain vegetables/plant/seed oils as a carrier, increases the bioefficacy and residual control of products through increase in penetration of active ingredients into leaf surface, improves the retention of active ingredietns on leaf surface especially on waxy leaf surface, improves the spreading properties and thereby improves the spray coverage.
Examples of Carrier used herein for WG (Wettable Granule) formulation includes but not limited to china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay,bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulfate, sodium chloride, gypsum, calcium sulfate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulfate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers.

The process for preparing the present novel synergistic composition can be modified accordingly by any person skilled in the art based on the knowledge of the manufacturing the formulation. However all such variation and modification is still covered by the scope of present invention.
Following the right use of the invented technology and the synergistic fungicidal composition of the invention with a formulations having a multi-pesticide components i.e. pesticide mixture, formulation prepared with an extra care of physical compatibility by purposefully specially selected solvents, dispersing agents, carriers and the surfactants, thickeners, stabilizers etc. exhibits better fungal and pest management and boost plant health.
While the foregoing written description of the invention enables one of ordinary skill to make and use what is considered presently to be the best mode thereof, those of ordinary skill will understand and appreciate the existence of variations, combinations, and equivalents of the specific embodiment, method, and examples herein. The invention should therefore not be limited by the above described embodiment, method, and examples, but by all embodiments and methods within the scope and spirit of the invention. The invention shall now be described with reference to the following specific examples. It should be noted that the example(s) appended below illustrate rather than limit the invention, and that those skilled in the art will be able to design many alternative embodiments without departing from the scope of the present invention.
These and other aspects of the invention may become more apparent from the examples set forth herein below. These examples are provided merely as illustrations of the invention and are not intended to be construed as a limitation thereof.
EXAMPLE 1:
WG (Water dispersible granule/Wettable Granule) formulation of Methoxyfenozide 14%+Chlorothalonil 40%+Azoxystrobin 4.8%
Chemical composition % (w/w)
Methoxyfenozide a.i. 14.00
Chlorothalonil a.i. 40.00
Azoxystrobin a.i. 4.80
Wetting agent 3.50
Dispersing agent I 6.00
Dispersing agent II 8.00
Disintegrating agent 1.50
Antifoaming agent 1.00
Carrier 21.20
Total 100.00

Storage stability-
Methoxyfenozide 14%+Chlorothalonil 40%+Azoxystrobin 4.8% WG (Water dispersible granule/ Wettable Granule) formulation
Laboratory storage for 14 days
Parameters Specification (in house) Initial At 54±2 0C At 0±2 0C
Methoxyfenozide content percent by mass 13.3 to 14.7 14.50 14.30 14.40
Chlorothalonil content percent by mass 38 to 42 41.50 41.20 41.40
Azoxystrobin content percent by mass 4.56 to 5.28 5.10 5.00 5.05
Methoxyfenozide suspensibility percent min. 70 98.50 97.60 98.20
Chlorothalonil suspensibility percent min. 70 96.50 95.60 96.00
Azoxystrobin suspensibility percent min. 70 96.50 95.20 95.60
pH range (1% aq. Suspension) 5.0 to 8.0 6.50 6.40 6.50
Wettability sec. max. 60 7 8 8
Wet sieve (45 micron) percent by mass min. 98.5 99.6 99.2 99.5
Bulk density (g/ml) 0.45 to 0.65 0.5 0.5 0.5
Moisture content percent by mass max. max. 2% 2 2 2
Room temperature storage stability up to 12 months
Parameters specification (in house) 1 month 6 months 12 months
Methoxyfenozide content percent by mass 13.3 to 14.7 14.50 14.40 14.20
Chlorothalonil content percent by mass 38 to 42 41.50 41.30 41.00
Azoxystrobin content percent by mass 4.56 to 5.28 5.10 5.00 4.90
Methoxyfenozide suspensibility percent min. 70 98.50 98.00 97.50
Chlorothalonil suspensibility percent min. 70 96.50 96.00 95.00
Azoxystrobin suspensibility percent min. 70 96.50 96.00 95.50
pH range (1% aq. Suspension) 5.0 to 8.0 6.50 6.40 6.50
Wettability sec. max. 60 7 8 8
Wet sieve (45 micron) percent by mass min. 98.5 99.6 99.3 99.2
Bulk density (g/ml) 0.45 to 0.65 0.5 0.5 0.5
Moisture content percent by mass max. max. 2% 2 2 2

Procedure: Manufacturing process for WG (Water dispersible granule/ Wettable Granule) formulation
Step 1 Before starting the process, check the cleanliness of all equipment’s in plant and get approval by QC dept.
Step 2 Check the electrical connection and standardize the weighing balance.
Step 3 Take exact weight of active ingredients (technical) in blender and then add required quantity of binder & surfactants and mix it till its complete homogenization.
Step 4 Mill this homogenized Mixture till required wet sieve and post blend again for homogeneity.
Step 5 Pass the above homogenous material through Extruder for granulation.
Step 6 Now transfer the granules through Fluid Bed Dryer to remove excess moisture.
Step 7 Transfer these granules to vibro shifter.
Step 8 Collect the final material from the vibro shifter into drum.
Step 9 Finally send the sample to QC for approval.
Step 10 After approval by QC, transfer the material into different size of drums.

EXAMPLE 2:
WG (Water dispersible granule/Wettable Granule) formulation of Methoxyfenozide 12%+Propineb 45%+Fluxapyroxad 4%
Chemical composition % (w/w)
Methoxyfenozide a.i. 12.00
Propineb a.i. 45.00
Fluxapyroxad a.i. 4.00
Wetting agent 3.50
Dispersing agent I 6.00
Dispersing agent II 8.00
Disintegrating agent 1.50
Antifoaming agent 1.00
Carrier 19.00
Total 100.00

Storage stability-
Methoxyfenozide 12%+ Propineb 45% +Fluxapyroxad 4% WG (Water dispersible granule/ Wettable Granule) formulation

Laboratory storage for 14 days
Parameters Specification (in house) Initial At 54±2 0C At 0±2 0C
Methoxyfenozide content percent by mass 11.4 to 12.6 12.50 12.20 12.40
Propineb content percent by mass 42.75 to 47.25 45.45 45.30 45.44
Fluxapyroxad content percent by mass 3.8 to 4.4 4.25 4.20 4.24
Methoxyfenozide suspensibility percent min. 70 98.50 97.60 98.20
Propineb suspensibility percent min. 70 96.00 95.40 95.80
Fluxapyroxad suspensibility percent min. 70 97.00 96.00 96.80
pH range (1% aq. Suspension) 5.0 to 9.0 6.80 7.10 6.85
Wettability sec. max. 60 6 7 7
Wet sieve (45 micron) percent by mass min. 98.5 99.5 98.8 99.2
Bulk density (g/ml) 0.45 to 0.65 0.55 0.55 0.55
Moisture content percent by mass max. max. 2% 2 2 2
Room temperature storage stability up to 12 months
Parameters specification (in house) 1 month 6 months 12 months
Methoxyfenozide content percent by mass 11.4 to 12.6 12.50 12.50 12.48
Propineb content percent by mass 42.75 to 47.25 45.45 45.45 45.44
Fluxapyroxad content percent by mass 3.8 to 4.4 4.25 4.25 4.24
Methoxyfenozide suspensibility percent min. 70 98.50 97.60 98.20
Propineb suspensibility percent min. 70 96.00 95.40 95.80
Fluxapyroxad suspensibility percent min. 70 97.00 96.00 96.80
pH range (1% aq. Suspension) 5.0 to 9.0 6.80 7.10 6.85
Wettability sec. max. 60 6 7 7
Wet sieve (45 micron) percent by mass min. 98.5 99.5 98.8 99.2
Bulk density (g/ml) 0.45 to 0.65 0.55 0.55 0.55
Moisture content percent by mass max. max. 2% 2 2 2

Procedure: Manufacturing process as per example 1
EXAMPLE 3:
WG (Water dispersible granule/Wettable Granule) formulation of Methoxyfenozide 16%+Metiram 50%+Prothioconazole 5%
Chemical composition % (w/w)
Methoxyfenozide a.i. 16.00
Metiram a.i. 50.00
Prothioconazole a.i. 5.00
Wetting agent 3.50
Dispersing agent I 8.00
Dispersing agent II 10.00
Disintegrating agent 0.50
Antifoaming agent 1.00
Carrier 6.00
Total 100.00

Storage stability-
Methoxyfenozide 16%+Metiram 50%+Prothioconazole 5% WG (Water dispersible granule/ Wettable Granule) formulation
Laboratory storage for 14 days
Parameters Specification (in house) Initial At 54±2 0C At 0±2 0C
Methoxyfenozide content percent by mass 15.20 to 16.80 16.30 16.20 16.25
Metiramcontent percent by mass 47.50 to 52.50 50.50 50.25 50.49
Prothioconazole content percent by mass 4.75 to 5.50 5.20 5.10 5.20
Methoxyfenozide suspensibility percent min. 70 98.50 97.60 98.20
Metiram suspensibility percent min. 70 96.00 95.40 95.80
Prothioconazole suspensibility percent min. 70 97.00 96.00 96.80
pH range (1% aq. Suspension) 5.5 to 9.0 6.80 7.10 6.85
Wettability sec. max. 60 6 7 7
Wet sieve (45 micron) percent by mass min. 98.5 99.5 98.8 99.2
Bulk density (g/ml) 0.45 to 0.65 0.55 0.55 0.55
Moisture content percent by mass max. max. 2% 2 2 2
Room temperature storage stability up to 12 months
Parameters specification (in house) 1 month 6 months 12 months
Methoxyfenozide content percent by mass 15.20 to 16.80 16.30 16.30 16.25
Metiramcontent percent by mass 47.50 to 52.50 50.50 50.50 50.49
Prothioconazole content percent by mass 4.75 to 5.50 5.20 5.20 5.20
Methoxyfenozide suspensibility percent min. 70 98.50 97.60 98.20
Metiram suspensibility percent min. 70 96.00 95.40 95.80
Prothioconazole suspensibility percent min. 70 97.00 96.00 96.80
pH range (1% aq. Suspension) 5.5 to 9.0 6.80 7.10 6.85
Wettability sec. max. 60 6 7 7
Wet sieve (45 micron) percent by mass min. 98.5 99.5 98.8 99.2
Bulk density (g/ml) 0.45 to 0.65 0.55 0.55 0.55
Moisture content percent by mass max. max. 2% 2 2 2

Procedure: Manufacturing process as per example 1

EXAMPLE 4:
Most preferred formulations:

Compound A-Diacylhydrazines group Compound B-Multisite action fungicide Compound C-Fungicide/(s) Active ingredients (%) Formulation Strength (%) Formulation Type
Compound A Compound B Compound C
Methoxyfenozide Chlorothalonil Azoxystrobin 14 40 5 59.00 WG
Methoxyfenozide Chlorothalonil Pyraclostrobin 14 40 5 59.00 WG
Methoxyfenozide Mancozeb Azoxystrobin 14 40 5 59.00 WG
Methoxyfenozide Mancozeb Pyraclostrobin 14 40 5 59.00 WG
Methoxyfenozide Metiram Azoxystrobin 14 55 5 74.00 WG
Methoxyfenozide Metiram Pyraclostrobin 14 55 5 74.00 WG
Methoxyfenozide Propineb Azoxystrobin 14 50 5 69.00 WG
Methoxyfenozide Propineb Pyraclostrobin 14 50 5 69.00 WG
Methoxyfenozide Chlorothalonil Tebuconazole 16 50 5 71.00 WG
Methoxyfenozide Chlorothalonil Prothioconazole 16 50 5 71.00 WG
Methoxyfenozide Mancozeb Tebuconazole 16 50 5 71.00 WG
Methoxyfenozide Mancozeb Prothioconazole 16 50 5 71.00 WG
Methoxyfenozide Metiram Tebuconazole 16 50 5 71.00 WG
Methoxyfenozide Metiram Prothioconazole 16 50 5 71.00 WG
Methoxyfenozide Propineb Tebuconazole 16 50 5 71.00 WG
Methoxyfenozide Propineb Prothioconazole 16 50 5 71.00 WG
Methoxyfenozide Chlorothalonil Benzovindiflupyr 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Bixafen 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Fluxapyroxad 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Isopyrazam 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Penflufen 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Penthiopyrad 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Isoflucypyram 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Boscalid 14 40 4 58.00 WG
Methoxyfenozide Chlorothalonil Fluopyram 14 40 4 58.00 WG
Methoxyfenozide Mancozeb Fluxapyroxad 12 45 4 61.00 WG
Methoxyfenozide Propineb Fluxapyroxad 12 45 4 61.00 WG
Methoxyfenozide Chlorothalonil Fluxapyroxad 12 45 4 61.00 WG
Methoxyfenozide Metiram Fluxapyroxad 12 40 5 57.00 WG
Methoxyfenozide Captan Fluxapyroxad 12 40 5 57.00 WG
Methoxyfenozide Copper Fluxapyroxad 12 40 5 57.00 WG
Methoxyfenozide Metiram Benzovindiflupyr 14 50 4 68.00 WG
Methoxyfenozide Metiram Bixafen 14 50 4 68.00 WG
Methoxyfenozide Metiram Isopyrazam 14 50 4 68.00 WG
Methoxyfenozide Metiram Penflufen 14 50 4 68.00 WG
Methoxyfenozide Metiram Penthiopyrad 14 50 4 68.00 WG
Methoxyfenozide Metiram Isoflucypyram 14 50 4 68.00 WG
Methoxyfenozide Metiram Boscalid 14 50 4 68.00 WG
Methoxyfenozide Metiram Fluopyram 14 50 4 68.00 WG
Methoxyfenozide Propineb Benzovindiflupyr 14 50 4 68.00 WG
Methoxyfenozide Propineb Bixafen 14 50 4 68.00 WG
Methoxyfenozide Propineb Isopyrazam 14 50 4 68.00 WG
Methoxyfenozide Propineb Penflufen 14 50 4 68.00 WG
Methoxyfenozide Propineb Penthiopyrad 14 50 4 68.00 WG
Methoxyfenozide Propineb Isoflucypyram 14 50 4 68.00 WG
Methoxyfenozide Propineb Boscalid 14 50 4 68.00 WG
Methoxyfenozide Propineb Fluopyram 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Benzovindiflupyr 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Bixafen 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Isopyrazam 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Penflufen 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Penthiopyrad 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Isoflucypyram 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Boscalid 14 50 4 68.00 WG
Methoxyfenozide Chlorothalonil Fluopyram 14 50 4 68.00 WG

BIOLOGICAL EXAMPLES:
A synergistic effect exists wherever the action of a combination of active ingredient is greater than the sum of the action of each of the components alone. Therefore, a synergistically effective amount or an effective amount of a synergistic composition or combination is an amount that exhibits greater pesticidal activity than the sum of the pesticidal activities of the individual components.
In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “ Calculation of the synergistic and antagonistic responses of herbicide combinations” published in the journal Weeds, 1967, 15, p.20-22, incorporated herein by reference in its entirety. The action expected for a given combination of two or three active components can be calculated as follows:

FIELD BIO-EFFICACY STUDIES:
The field trials have been carried out on different crops to judge the synergism and benefits of innovative ready-mix combinations in comparison to prior arts.

Experiment 1: Control of insect-pest and diseases of groundnut
Crop : Groundnut
Location : Idar, Gujarat
Plot size : 30 sq. mt. (6m x 5m)
Number of Treatments: 30
Application Time : 60 DAS (Days after sowing)
Spray volume : 400 liter/h
Method of Application: Foliar spray with battery operated knap sack sprayer
Agronomic Practices : All agronomic practices followed as per the crop requirement except insect and disease control.
Observation Methods:
Spodoptera (Spodoptera litura) larval control (%):
10 plants per plot were selected randomly. Count the number of live larvae per plant. Calculate % larval control. Record the observations on 7th days after spraying.

Rust (Puccinia arachidis) disease: Randomly 20 plants per plot were observed for rust disease incidence and severity at 10 days after spray by adopting following scale.
Groundnut rust disease scale and disease severity(%)-
1=No disease (0 %),
2=Pustules sparsely distributed, largely on lower leaves (1-5%),
3=Many pustules on lower leaves, necrosis evident; very few pustules on middle leaves (6-10%), 4=Numerous pustules on lower and middle leaves; severe necrosis on lower leaves (11-20%), 5=Severe necrosis of lower and middle leaves; pustules may be present on top leaves, but less severe (21-30%),
6=Extensive damage to lower leaves; middle leaves necrotic, with dense distribution of pustules; pustules on top leaves (31-40%),
7=Severe damage to lower and middle leaves; pustules densely distributed on top leaves (41- 60%),
8=100% damage to lower and middle leaves; pustules on top leaves, which are severely necrotic (61-80%),
9=Almost all leaves withered; bare sterns seen (81-100%)
% Disease Index (PDI) was calculated by using following formula and calculated % disease control.


% Disease control data used to calculate synergism by applying Colby’s formula.

Table 1: Treatment details
Treatment Number Treatment composition with application rate per hectare
T1 Methoxyfenozide 14%+Chlorothalonil 40%+Azoxystrobin 4.8% WG-1500 g (ready-mix)
T2 Methoxyfenozide 14%+Chlorothalonil 40%+Pyraclostrobin 4.8% WG-1500 g (ready-mix)
T3 Methoxyfenozide 14%+Mancozeb 40%+Azoxystrobin 4.8% WG-1500 g (ready-mix)
T4 Methoxyfenozide 14%+Mancozeb 40%+Pyraclostrobin 4.8% WG-1500 g (ready-mix)
T5 Methoxyfenozide 14%+Metiram 55%+Azoxystrobin 5% WG-1500 g (ready-mix)
T6 Methoxyfenozide 14%+Metiram 55%+Pyraclostrobin 5% WG-1500 g (ready-mix)
T7 Methoxyfenozide 14%+Propineb 55%+Azoxystrobin 5% WG-1500 g (ready-mix)
T8 Methoxyfenozide 14%+Propineb 55%+Pyraclostrobin 5% WG-1500 g (ready-mix)
T9 Methoxyfenozide 21.8% SC-875 ml+Chlorothalonil 75% WP-800 g (prior art)
T10 Methoxyfenozide 21.8% SC-875 ml+Mancozeb 75% WG-800 g (prior art)
T11 Methoxyfenozide 21.8% SC-875 ml+Metiram 70% WG-1179 g (prior art)
T12 Methoxyfenozide 21.8% SC-875 ml+Propineb 70% WP-1071 g (prior art)
T13 Chlorothalonil 75% WP-800 g+Azoxystrobin 23% SC-300 ml (prior art)
T14 Mancozeb 75% WG-800 g+Azoxystrobin 23% SC-300 ml(prior art)
T15 Metiram 70% WG-1179 g+Azoxystrobin 23% SC-300 ml (prior art)
T16 Propineb 70% WP-1071 g+Azoxystrobin 23% SC-300 ml(prior art)
T17 Chlorothalonil 75% WP-800 g+Pyraclostrobin 20% WG-375 g (prior art)
T18 Mancozeb 75% WG-800 g+Pyraclostrobin 20% WG-375 g (prior art)
T19 Metiram 70% WG-1179 g+Pyraclostrobin 20% WG-375 g (prior art)
T20 Propineb 70% WP-1071 g+Pyraclostrobin 20% WG-375 g (prior art)
T21 Methoxyfenozide 21.8% SC-875 ml+Azoxystrobin 23% SC-300 ml (prior art)
T22 Methoxyfenozide 21.8% SC-875 ml+Pyraclostrobin 20% WG-375 g (prior art)
T23 Chlorothalonil 75% WP-800 g
T24 Mancozeb 75% WG-800 g
T25 Metiram 70% WG-1179 g
T26 Propineb 70% WP-1071 g
T27 Methoxyfenozide 21.8% SC-875 ml
T28 Azoxystrobin 23% SC-300 ml
T29 Pyraclostrobin 20% WG-375 g
T30 UTC (Untreated Check)

Methoxyfenozide 21.8% w/w SC (24% w/v).
Table 2: Control of rust disease and Spodoptera in groundnut
Treatment Number % Rust disease control Synergism (Y/N) % Spodoptera larval control Number of pods per plant % Increase in Pods over T30
Obs. Value Cal. Value Colby's ratio
T1 98.6 83.18 1.19 Y 85.6 28.60 66.3
T2 97.2 82.90 1.17 Y 84.8 27.80 61.6
T3 95.8 82.54 1.16 Y 84.4 28.40 65.1
T4 97.4 83.27 1.17 Y 85.6 27.60 60.5
T5 98.2 84.66 1.16 Y 85.4 28.00 62.8
T6 97.6 84.41 1.16 Y 84.4 28.20 64.0
T7 96.2 84.08 1.14 Y 84.0 27.80 61.6
T8 97.4 84.75 1.15 Y 84.2 28.00 62.8
T9 64.8 66.22 0.98 N 80.2 22.60 31.4
T10 65.0 65.67 0.99 N 79.8 21.80 26.7
T11 63.2 64.93 0.97 N 79.4 22.40 30.2
T12 64.2 66.40 0.97 N 79.2 21.60 25.6
T13 74.6 81.67 0.91 N 17.8 24.80 44.2
T14 75.2 81.37 0.92 N 15.6 23.60 37.2
T15 76.4 80.98 0.94 N 14.2 24.20 40.7
T16 77.2 81.77 0.94 N 15.2 23.80 38.4
T17 82.8 83.29 0.99 N 18.6 24.40 41.9
T18 82.4 83.02 0.99 N 16.8 24.60 43.0
T19 81.6 82.66 0.99 N 14.8 23.40 36.0
T20 82.6 83.38 0.99 N 15.4 23.80 38.4
T21 52.6 54.28 0.97 N 79.2 24.00 39.5
T22 56.4 58.32 0.97 N 79.4 24.20 40.7
T23 63.2 N 12.6 18.60 8.1
T24 62.6 N 10.6 18.80 9.3
T25 61.8 N 8.6 19.20 11.6
T26 63.4 N 9.2 19.80 15.1
T27 8.2 N 78.4 17.80 3.5
T28 50.2 N 6.8 21.60 25.6
T29 54.6 N 7.2 20.80 20.9
T30 0.0 N 0.0 17.20 0.0

All the ready-mix innovative combinations (T1, T2, T3, T4, T5 and T6) shows synergism in terms of rust disease control and spodoptera larval control. It also produces higher number of pods/plant (>60% higher than T30-UTC) in comparison to all prior arts and untreated control (T30).
Experiment 2: Control of insect-pest and diseases of chilly, Capsicum annum
Crop : Chilly
Location : Umreth, Gujarat
Plot size : 40 sq. mt. (8m x 5m)
Number of Treatments: 30
Application Time : 75 DATP (Days after transplanting)
Spray volume : 480 liter/h
Method of Application: Foliar spray with battery operated knap sack sprayer
Agronomic Practices : All agronomic practices followed as per the crop requirement except insect and disease control.
Observation Methods:
Fruit borer (Spodoptera exigua and Helicoverpa armigera mixed infestation) larval control (%):
10 plants per plot were selected randomly. Count the number of live larvae per plant. Calculate % larval control. Record the observations on 7th days after spraying.

Fruit rot (Colletotrichum capsici): The data on % intensity of fruit rot were recorded on 10th days after spray. The data on incidence was recorded on 10 randomly selected plants (25 fruit per each plant) from each replication. The fruit rot was scored in 0-5 scale (0= no infection, 1= 1-5% infection, 2= 6-10%, 3=11-25%, 4= 26-50%, 5= > 51%.)
% Disease Index (PDI) was calculated by using formula (as given in Experiment 1) and calculated % disease control. % Disease control data used to calculate synergism by applying Colby’s formula.

Table 3: Treatment details
Treatment Number Treatment composition with application rate per hectare
T1 Methoxyfenozide 16%+Chlorothalonil 50%+Tebuconazole 5% WG-1250 g (ready-mix)
T2 Methoxyfenozide 16%+Chlorothalonil 50%+Prothioconazole 5% WG-1250 g (ready-mix)
T3 Methoxyfenozide 16%+Mancozeb 50%+Tebuconazole 5% WG-1250 g (ready-mix)
T4 Methoxyfenozide 16%+Mancozeb 50%+Prothioconazole 5% WG-1250 g (ready-mix)
T5 Methoxyfenozide 16%+Metiram 50%+Tebuconazole 5% WG-1250 g (ready-mix)
T6 Methoxyfenozide 16%+Metiram 50%+Prothioconazole 5% WG-1250 g (ready-mix)
T7 Methoxyfenozide 16%+Propineb 50%+Tebuconazole 5% WG-1250 g (ready-mix)
T8 Methoxyfenozide 16%+Propineb 50%+Prothioconazole 5% WG-1250 g (ready-mix)
T9 Methoxyfenozide 21.8% SC-833.3 ml+Chlorothalonil 75% WP-833.3 g (prior art)
T10 Methoxyfenozide 21.8% SC-833.3 ml+Mancozeb 75% WG-833.3 g (prior art)
T11 Methoxyfenozide 21.8% SC-833.3 ml+Metiram 70% WG-892.9 g (prior art)
T12 Methoxyfenozide 21.8% SC-833.3 ml+Propineb 70% WP-892.9 g (prior art)
T13 Chlorothalonil 75% WP-833.3 g+Tebuconazole 25% WG-250 g (prior art)
T14 Mancozeb 75% WG-833.3 g+Tebuconazole 25% WG-250 g (prior art)
T15 Metiram 70% WG-892.9 g+Tebuconazole 25% WG-250 g (prior art)
T16 Propineb 70% WP-892.9 g+Tebuconazole 25% WG-250 g (prior art)
T17 Chlorothalonil 75% WP-833.3 g+Prothioconazole 50% EC-125 ml (prior art)
T18 Mancozeb 75% WG-833.3g +Prothioconazole 50% EC-125 ml (prior art)
T19 Metiram 70% WG-892.9 g+Prothioconazole 50% EC-125 ml (prior art)
T20 Propineb 70% WP-892.9 g +Prothioconazole 50% EC-125 ml (prior art)
T21 Methoxyfenozide 21.8% SC-833.3 ml+Tebuconazole 25% WG-250 g (prior art)
T22 Methoxyfenozide 21.8% SC-833.3 ml+Prothioconazole 50% EC-125 ml (prior art)
T23 Chlorothalonil 75% WP-833.3 g
T24 Mancozeb 75% WG-833.3 g
T25 Metiram 70% WG-892.9 g
T26 Propineb 70% WP-892.9 g
T27 Methoxyfenozide 21.8% SC-833.3 ml
T28 Tebuconazole 25% WG-250 g
T29 Prothioconazole 50% EC-125 ml
T30 UTC (Untreated Check)

Methoxyfenozide 21.8% w/w SC (24% w/v).
Table 4: Control of fruit rot disease and fruit borer in chilly
Treatment Number % Fruit rot disease control Synergism (Y/N) % Fruit borer larval control Number of fruits per plant % Increase in healthy fruits over T30
Obs. Value Cal. Value Colby's ratio
T1 96.2 84.95 1.13 Y 88.8 52.4 84.5
T2 94.8 83.94 1.13 Y 89.2 51.2 80.3
T3 95.8 84.52 1.13 Y 88.4 51.4 81.0
T4 95.2 85.32 1.12 Y 89.0 52.4 84.5
T5 94.8 85.64 1.11 Y 87.6 51.8 82.4
T6 95.2 84.67 1.12 Y 88.4 52.6 85.2
T7 94.8 85.23 1.11 Y 89.4 51.6 81.7
T8 96.2 85.99 1.12 Y 88.2 51.4 81.0
T9 59.8 61.81 0.97 N 81.6 44.6 57.0
T10 58.8 59.24 0.99 N 81.8 45.2 59.2
T11 59.4 60.71 0.98 N 81.4 43.8 54.2
T12 61.2 62.73 0.98 N 81.0 44.4 56.3
T13 82.4 83.61 0.99 N 16.2 42.8 50.7
T14 81.2 82.51 0.98 N 10.8 44.6 57.0
T15 81.8 83.14 0.98 N 11.2 43.8 54.2
T16 82.6 84.00 0.98 N 9.6 43.2 52.1
T17 81.2 84.36 0.96 N 8.6 42.0 47.9
T18 82.0 83.31 0.98 N 10.4 43.6 53.5
T19 81.6 83.91 0.97 N 9.6 44.0 54.9
T20 83.6 84.73 0.99 N 8.2 43.8 54.2
T21 61.6 63.83 0.97 N 81.0 47.8 68.3
T22 63.2 65.48 0.97 N 81.4 47.2 66.2
T23 58.4 8.8 35.2 23.9
T24 55.6 9.6 36.4 28.2
T25 57.2 9.2 35.4 24.6
T26 59.4 8.6 36.2 27.5
T27 8.2 80.4 36.8 29.6
T28 60.6 8.4 39.2 38.0
T29 62.4 9.0 39.8 40.1
T30 0.0 0.0 28.4 0.0

All the ready-mix innovative combinations (T1, T2, T3, T4, T5 and T6) shows synergism in terms of fruit rot disease control and fruit borer larval control. It also produces higher number of healthy fruits/plant (>80% higher than T30-UTC) in comparison to all prior arts and untreated control (T30).
Experiment 3: Control of insect-pest and diseases of tomato, Solanum lycopersicum
Crop : Tomato
Location : Tarapur, Gujarat
Plot size : 40 sq. mt. (8m x 5m)
Number of Treatments: 30
Application Time : 80 DATP (Days after transplanting)
Spray volume : 540 liter/h
Method of Application: Foliar spray with battery operated knap sack sprayer
Agronomic Practices : All agronomic practices followed as per the crop requirement except insect and disease control.
Observation Methods:
Fruit borer (Helicoverpa armigera) larval control (%):
10 plants per plot were selected randomly. Count the number of live larvae per plant. Calculate % larval control. Record the observations on 7th days after spraying.

Early blight (Alternaria solani): The data on % intensity of early blight were recorded on 10th days after spray. The early blight disease was scored in 0-5 scale (0= no infection, 1= 1-5% infection, 2= 6-10%, 3=11-25%, 4= 26-50%, 5= > 51%.)
% Disease Index (PDI) was calculated by using formula (as given in Experiment 1) and calculated % disease control. % Disease control data used to calculate synergism by applying Colby’s formula.
Table 5: Treatment details
Treatment Number Treatment composition with application rate per hectare
T1 Methoxyfenozide 12%+Mancozeb 45%+Fluxapyroxad 4% WG-1500 g
T2 Methoxyfenozide 12%+Propineb 45%+Fluxapyroxad 4% WG-1500 g
T3 Methoxyfenozide 12%+Chlorothalonil 45%+Fluxapyroxad 4% WG-1500 g
T4 Methoxyfenozide 12%+Metiram 40%+Fluxapyroxad 5% WG-1500 g
T5 Methoxyfenozide 12%+Captan 40%+Fluxapyroxad 5% WG-1500 g
T6 Methoxyfenozide 12%+Copper 40%+Fluxapyroxad 5% WG-1500 g
T7 Methoxyfenozide 21.8% SC-750 ml+Mancozeb 75% WG-900 g (prior art)
T8 Methoxyfenozide 21.8% SC-750 ml+Propineb 70% WP-964.3 g (prior art)
T9 Methoxyfenozide 21.8% SC-750 ml+Chlorothalonil 75% WP-900 g (prior art)
T10 Methoxyfenozide 21.8% SC-750 ml+Metiram 70% WG-857.1 g (prior art)
T11 Methoxyfenozide 21.8% SC-750 ml+Captan 50% WP-1200 g (prior art)
T12 Methoxyfenozide 21.8% SC-750 ml+Copper Oxychloride 50% WP-1200 g (prior art)
T13 Methoxyfenozide 21.8% SC-750 ml+Fluxapyroxad 25% SC-240 ml (prior art)
T14 Methoxyfenozide 21.8% SC-750 ml+Fluxapyroxad 25% SC-300 ml (prior art)
T15 Mancozeb 75% WG-900 g+Fluxapyroxad 25% SC-240 ml (prior art)
T16 Propineb 70% WP-964.3 g+Fluxapyroxad 25% SC-240 ml (prior art)
T17 Chlorothalonil 75% WP-900 g+Fluxapyroxad 25% SC-240 ml (prior art)
T18 Metiram 70% WG-857.1 g+Fluxapyroxad 25% SC-300 ml (prior art)
T19 Captan 50% WP-1200 g+Fluxapyroxad 25% SC-300 ml (prior art)
T20 Copper Oxychloride 50% WP-1200 g+Fluxapyroxad 25% SC-300 ml (prior art)
T21 Methoxyfenozide 21.8% SC-750 ml
T22 Mancozeb 75% WG-900 g (prior art)
T23 Propineb 70% WP-964.3 g (prior art)
T24 Chlorothalonil 75% WP-900 g (prior art)
T25 Metiram 70% WG-857.1 g (prior art)
T26 Captan 50% WP-1200 g (prior art)
T27 Copper Oxychloride 50% WP-1200 g (prior art)
T28 Fluxapyroxad 25% SC-240 ml
T29 Fluxapyroxad 25% SC-300 ml
T30 UTC (Untreated Check)
Methoxyfenozide 21.8% w/w SC (24% w/v).
Table 6: Control of Early blight disease and fruit borer in tomato crop
Treatment Number Early blight disease control (%) % Fruit borer larval control Synergism (Y/N) Number of Healthy fruits/plant % Increase in healthy fruits over T30
Obs. Value Cal. Value Colby's ratio
T1 92.6 82.76 1.12 88.2 Y 42.6 80.5
T2 90.4 82.96 1.09 89.4 Y 43.4 83.9
T3 91.2 83.36 1.09 87.6 Y 44.2 87.3
T4 92.4 85.55 1.08 86.8 Y 43.6 84.7
T5 93.2 84.13 1.11 89.4 Y 42.8 81.4
T6 91.6 83.95 1.09 88.2 Y 44.4 88.1
T7 53.2 54.15 0.98 84.6 N 38.6 63.6
T8 52.6 54.69 0.96 85.2 N 37.8 60.2
T9 54.8 55.76 0.98 83.8 N 36.6 55.1
T10 55.4 56.47 0.98 84.4 N 38.4 62.7
T11 51.4 52.19 0.98 83.6 N 37.4 58.5
T12 50.8 51.65 0.98 83.2 N 38.0 61.0
T13 65.8 66.46 0.99 84.2 N 40.2 70.3
T14 69.8 70.39 0.99 85.0 N 40.8 72.9
T15 79.2 80.67 0.98 5.2 N 32.6 38.1
T16 80.2 80.90 0.99 4.8 N 32.4 37.3
T17 81.4 81.35 1.00 6.4 N 32.0 35.6
T18 84.0 83.80 1.00 5.4 N 34.2 44.9
T19 82.4 82.20 1.00 6.2 N 33.8 43.2
T20 82.2 82.01 1.00 5.8 N 33.6 42.4
T21 10.8 85.8 31.2 32.2
T22 48.6 4.8 28.6 21.2
T23 49.2 5.2 27.8 17.8
T24 50.4 4.4 26.8 13.6
T25 51.2 3.8 27.4 16.1
T26 46.4 5.2 28.2 19.5
T27 45.8 4.6 26.8 13.6
T28 62.4 5.2 29.6 25.4
T29 66.8 5.6 30.8 30.5
T30 0.0 0.0 23.6 0.0

All the ready-mix innovative combinations (T1, T2, T3, T4, T5 and T6) shows synergism in terms of early blight disease control and fruit borer (Helicoverpa armigera) larval control. It also produces higher number of healthy fruits/plant (>80% higher than T30-UTC) in comparison to all prior arts and untreated control (T30).

Overall summery of field trials:
The field trials results shows many benefits/advantages of ready mix formulations of methoxyfenozide + multisite fungicide + one more fungicide.
• Synergism observed in terms of insect and disease control
• Provides higher level of insect and disease control (increase in % control)
• Provides longer duration of control (residual control)
• Increases plant growth, vigor, height, produces a greater number of tillers, shoots, branches, flowers, fruits, pods, square, bolls, seeds, grains etc. and overall biomass of the crop, which directly increases the yield of the crop.
[Terminology used in bio-efficacy trials are cm-centimetre, m- meter, g-gram, kg-kilogram, ml-millilitre, sq.mt. square meter (m2), DAS Days after sowing, DAP Days after planting, DATP Days after transplanting, DAA Days after application, T for Treatment, spp.-species, Ob. Value-observed value, Cal.Value-calculated value.]
,CLAIMS:CLAIMS
We claim;
[CLAIM 1]. A synergistic pesticidal composition comprising:
a. at least one insecticide selected from Diacylhydrazines group present in an amount of 5 to 25 % by weight or mixture thereof;
b. at least one multisite action fungicide selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds present in an amount of 20 to 60 % by weight or mixture thereof;
c. a fungicide selected from class of nucleic acid synthesis inhibitors, cytoskeleton and motor protien inhibitors, amino acid and protein synthesis inhibitors, respiration process inhibitors, signal transduction inhibitors, lipid synthesis and membrane integrity disruptors, sterol biosynthesis inhibitors present in an amount of 2 to 20 % by weight or mixture thereof
d. inactive formulation excipients.

[CLAIM 2]. The synergistic pesticidal composition as claimed in claim 1 wherein, an insecticide from diacylhydrazine group is selected from Chromafenozide, Halofenozide, Methoxyfenozide, Tebufenozide.

[CLAIM 3]. The synergistic pesticidal composition as claimed in claim 1 wherein, a multisite action fungicide is selected from dithiocarbamates, Inorganic copper, sulphur and relative group of compounds selected from the group of copper hydroxide, copper oxychloride, copper (II) sulphate, Bordeaux mixture, copper salicylate, cuprous oxide; ferbam, mancozeb, maneb, metiram, propineb, thiram, zinc thiazole, zineb, ziram, phthalimides-captan, captafol, folpet, chloronitriles (phthalonitriles)-chlorothalonil, sulfamides-dichlofluanid, tolylfluanid, bis guanidines-guazatine, iminoctadine, triazines-anilazine, quinones (anthraquinones)-dithianon, quinoxalines-chinomethionat /quinomethionate, maleimide-fluoroimide, thiocarbamate –methasulfocarb.

[CLAIM 4]. The synergistic pesticidal composition as claimed in claim 1 wherein, a fungicide
from the nucleic acid synthesis inhibitors class is selected from benalaxyl, benalaxyl-M (=kiralaxyl), furalaxyl, metalaxyl, metalaxyl-M (=mefenoxam), oxadixyl, ofurace, bupirimate, dimethirimol, ethirimol, hymexazole, octhilinone and oxolinic acid;
from the cytoskeleton and motor protien inhibitors class is selected from benomyl, carbendazim, fuberidazole, thiabendazole, thiophanate, thiophanate-methyl, diethofencarb, zoxamide, ethaboxam, pencycuron, fluopicolide, fluopimomide, phenamacril, metrafenone, pyriofenone
from amino acid and protein synthesis inhibitors class is selected from cyprodinil, mepanipyrim, pyrimethanil, blasticidin-S, kasugamycin, streptomycin, oxytetracycline;
from respiration process inhibitors class is selected from diflumetorim, tolfenpyrad, fenazaquin, benodanil, flutolanil, mepronil, isofetamid, fluopyram, fenfuram, carboxin, oxycarboxin, thifluzamide, benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, furametpyr, inpyrfluxam, isopyrazam, penflufen, penthiopyrad, sedaxane, isoflucypram, pydiflumetofen, boscalid, pyraziflumid, azoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, picoxystrobin, pyraoxystrobin, mandestrobin, pyraclostrobin, pyrametostrobin, triclopyricarb, kresoxim-methyl, trifloxystrobin, dimoxystrobin, fenaminstrobi metominostrobin, orysastrobin, famoxadone, fluoxastrobin, fenamidone, pyribencarb, metyltetraprole, cyazofamid, amisulbrom, fenpicoxamid, binapacryl, meptyldinocap, dinocap, fluazinam, fentin acetate, fentin chloride, fentin hydroxide, silthiofam, ametoctradin;
from signal transduction inhibitors class is selected from quinoxyfen, proquinazid, fenpiclonil, fludioxonil, chlozolinate, dimethachlone, iprodione, procymidone, vinclozolin;
from lipid synthesis and membrane integrity disruptors class is selected from edifenphos, iprobenfos (IBP), pyrazophos, isoprothiolane, biphenyl, chloroneb dicloran, quintozene (PCNB), tecnazene (TCNB,) tolclofos-methyl,,etridiazole,,iodocarb, propamocarb, prothiocarb, plant oils (mixtures): eugenol, geraniol, thymol, natamycin (pimaricin), oxathiapiprolin, fluoxapiprolin;
from sterol biosynthesis inhibitors class is selected from triforine, pyrifenox, pyrisoxazole, fenarimol, nuarimol, imazalil, oxpoconazole, pefurazoate, prochloraz, triflumizole, azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, prothioconazole, aldimorph, dodemorph, fenpropimorph, tridemorph, fenpropidin, piperalin, spiroxamine, fenhexamid, fenpyrazamine, pyributicarb, naftifine, terbinafine;
from melanin synthesis inhibitors class is selected from fthalide, pyroquilon, tricyclazole, carpropamid, diclocymet, fenoxanil, tolprocarb;

[CLAIM 5]. The synergistic pesticidal composition as claimed in claim 1 wherein, the formulation for the said composition is selected from Capsule suspension (CS), Dispersible concentrate (DC), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion for seed treatment (ES), Emulsion, oil in water (EW), Flowable suspension/concentrate for seed treatment (FS), Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), Solution for seed treatment (LS), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (= flowable concentrate) (SC), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Water soluble powder (SP), Water dispersible granule (WG or WDG), Wettable powder (WP), Water dispersible powder for slurry treatment (WS), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), A mixed formulation of CS and EW (ZW).

[CLAIM 6]. The synergistic pesticidal composition as claimed in claim 1-claim 5 wherein, the preferred composition for the Water Dispersible Granule/Wettable Granule (WG) formulation comprises:
i. Methoxyfenozide 14% + Chlorothalonil 40% + Azoxystrobin 5%
ii. Methoxyfenozide 14% + Chlorothalonil 40% + Pyraclostrobin 5%
iii. Methoxyfenozide 14% + Mancozeb 40% + Azoxystrobin 5%
iv. Methoxyfenozide 14% + Mancozeb 40% + Pyraclostrobin 5%
v. Methoxyfenozide 14% + Metiram 55% + Azoxystrobin 5%
vi. Methoxyfenozide 14% + Metiram 55% + Pyraclostrobin 5%
vii. Methoxyfenozide 14% + Propineb 50% + Azoxystrobin 5%
viii. Methoxyfenozide 14%+ Propineb 50% + Pyraclostrobin 5%
ix. Methoxyfenozide 16%+ Chlorothalonil 50%+ Tebuconazole 5%
x. Methoxyfenozide 16%+ Chlorothalonil 50% + Prothioconazole 5%
xi. Methoxyfenozide 16% + Mancozeb 50%+ Tebuconazole 5%
xii. Methoxyfenozide 16%+ Mancozeb 50%+ Prothioconazole 5%
xiii. Methoxyfenozide 16%+ Metiram 50%+ Tebuconazole 5%
xiv. Methoxyfenozide 16%+Metiram 50%+ Prothioconazole 5%
xv. Methoxyfenozide 16%+ Propineb 50%+ Tebuconazole 5%
xvi. Methoxyfenozide 16%+ Propineb 50%+ Prothioconazole 5%
xvii. Methoxyfenozide 14%+ Chlorothalonil 40%+ Benzovindiflupyr 4%
xviii. Methoxyfenozide 14%+ Chlorothalonil 40%+ Bixafen 4%
xix. Methoxyfenozide 14%+ Chlorothalonil 40%+ Fluxapyroxad 4%
xx. Methoxyfenozide 14%+ Chlorothalonil 40% + Isopyrazam 4%
xxi. Methoxyfenozide 14% + Chlorothalonil 40% + Penflufen 4%
xxii. Methoxyfenozide 14%+ Chlorothalonil 40%+ Penthiopyrad 4%
xxiii. Methoxyfenozide 14%+ Chlorothalonil 40%+ Isoflucypyram 4%
xxiv. Methoxyfenozide 14%+ Chlorothalonil 40%+ Boscalid 4%
xxv. Methoxyfenozide 14%+ Chlorothalonil 40%+ Fluopyram 4%
xxvi. Methoxyfenozide 12%+ Mancozeb 45% + Fluxapyroxad 4%
xxvii. Methoxyfenozide 12% + Propineb 45%+ Fluxapyroxad 4%
xxviii. Methoxyfenozide 12%+ Chlorothalonil 45%+ Fluxapyroxad 4%
xxix. Methoxyfenozide 12%+ Metiram 40%+ Fluxapyroxad 5%
xxx. Methoxyfenozide 12%+ Captan 40%+ Fluxapyroxad 5%
xxxi. Methoxyfenozide 12%+ Copper 40%+ Fluxapyroxad 5%
xxxii. Methoxyfenozide 14% + Metiram 50% + Benzovindiflupyr 4%
xxxiii. Methoxyfenozide 14% + Metiram 50%+ Bixafen 4%
xxxiv. Methoxyfenozide 14%+ Metiram 50%+ Isopyrazam 4%
xxxv. Methoxyfenozide 14%+ Metiram 50%+ Penflufen 4%
xxxvi. Methoxyfenozide 14%+ Metiram 50%+ Penthiopyrad 4%
xxxvii. Methoxyfenozide 14%+ Metiram 50%+ Isoflucypyram 4%
xxxviii. Methoxyfenozide 14%+ Metiram 50%+ Boscalid 4%
xxxix. Methoxyfenozide 14%+ Metiram 50%+ Fluopyram 4%
xl. Methoxyfenozide 14%+ Propineb 50%+ Benzovindiflupyr 4%
xli. Methoxyfenozide 14%+ Propineb 50%+ Bixafen 4%
xlii. Methoxyfenozide 14%+ Propineb 50%+ Isopyrazam 4%
xliii. Methoxyfenozide 14%+ Propineb 50%+ Penflufen 4%
xliv. Methoxyfenozide 14%+ Propineb 50%+ Penthiopyrad 4%
xlv. Methoxyfenozide 14%+ Propineb 50%+ Isoflucypyram 4%
xlvi. Methoxyfenozide 14%+ Propineb 50%+ Boscalid 4%
xlvii. Methoxyfenozide 14%+ Propineb 50%+ Fluopyram 4%
xlviii. Methoxyfenozide 14%+ Chlorothalonil 50%+ Benzovindiflupyr 4%
xlix. Methoxyfenozide 14%+ Chlorothalonil 50%+ Bixafen 4%
l. Methoxyfenozide 14%+ Chlorothalonil 50%+ Isopyrazam 4%
li. Methoxyfenozide 14%+ Chlorothalonil 50%+ Penflufen 4%
lii. Methoxyfenozide 14%+ Chlorothalonil 50%+ Penthiopyrad 4%
liii. Methoxyfenozide 14%+ Chlorothalonil 50%+ Isoflucypyram 4%
liv. Methoxyfenozide 14%+ Chlorothalonil 50%+ Boscalid 4%
lv. Methoxyfenozide 14%+ Chlorothalonil50%+ Fluopyram 4%

[CLAIM 7]. The synergistic pesticidal composition as claimed in claim 1 and claim 6, wherein the Water Dispersible Granule/Wettable Granule (WG) formulation comprises:
i. an insecticide from Diacylhydrazines group present in an amount of 5 to 25 % by weight by weight of the composition is selected from Methoxyfenozide;
ii. a multisite action fungicide present in an amount of 20 to 60 % by weight of the composition is selected from Chlorothalonil, Propineb, Metiram, Copper, Captan, Mancozeb;
iii. a fungicide selected from class of nucleic acid synthesis inhibitors, cytoskeleton and motor protien inhibitors, amino acid and protein synthesis inhibitors, respiration process inhibitors, signal transduction inhibitors, lipid synthesis and membrane integrity disruptors, sterol biosynthesis inhibitors present in an amount of 2 to 20 % by weight is selected from Azoxystrobin, Pyraclostrobin, Tebuconazole, Prothioconazole, Benzovindiflupyr, Bixafen, Fluxapyroxad, Isopyrazam, Penflufen, Penthiopyrad, Isoflucypyram, Boscalid, Fluopyram, Benzovindiflupyr
iv. Wetting agent in an amount of 2 to 6 % by weight;
v. Dispersing agent I in an amount of 2 to 8 % by weight;
vi. Dispersing agent II in an amount of 6 to 12 % by weight;
vii. Disintegrating agent in an amount of 0.5 to 4 % by weight;
viii. Antifoaming agent in an amount of 0.1 to 2 % by weight;
ix. Carrier in an amount of 5 to 30 % by weight.

[CLAIM 8]. The synergistic pesticidal composition as claimed in claim 7, wherein dispersing agent is selected from naphthalene sulfonic acid, sodium salt condensated with formaldehyde, poly alcoxylated alkyl phenol, naphthalene sulfonic acid formaldehyde condensate, methyl naphtaline-formaldehyde-condensate sodium salt, naphthalene condensates, lingo sulfonates, poly acrylates and phosphate esters, calcium lingo sulfonate, lignin sulfonate sodium salt.

[CLAIM 9]. The synergistic pesticidal composition as claimed in claim 7, wherein wetting agents is selected from sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridexyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkyaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and diisopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, Organosilicone surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, 10 mole ethylene oxide adduct of octylphenol, may or may not be in modified form, may be powder form.

[CLAIM 10]. The synergistic pesticidal composition as claimed in claim 7, wherein disintegrating agent is selected from citric acid, succinic acid or the sodium bicarbonate.

[CLAIM 11]. The synergistic pesticidal composition as claimed in claim 7, wherein carrier is selected from china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay,bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulfate, sodium chloride, gypsum, calcium sulfate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulfate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers.

[CLAIM 12]. The synergistic pesticidal composition as claimed in claim 7, wherein anti-foaming agent is polydimethylsiloxane or sodium alkylate.

Dated this 17th day of February 2021