DESC:FIELD OF THE INVENTION:
The present invention relates to synergistic pesticidal compositions comprising bioactive amounts of (A) an insecticide selected from the class of chordotonal organ modulators or mixture thereof; (B) a fungicide selected from the class of triazoles; (C) at least one insecticide selected from various class with different mode of action or mixture thereof. The present invention further relates to process of preparing said composition along with at least one inactive excipients and formulation thereof.

BACKGROUND OF THE INVENTION:

Combination of insecticides and fingicides are used to broaden the spectrum of control of insect and fungi, to improve the pest control with synergistc effect, reduce dosage, thereby reducing environmental impact, to broaden the spectrum of control, i.e. chewing and sucking insects and fungal disease at a time, decrease chances of resistance development and to enhance residual control so lesser the number of sprays for crop protections and minimizing the pesticidal load in ecosystem. The combination of insecticides and fungicides at times demonstrate an additive or synergistic effect that results in an improved control on the insect-pests and disease.
Insecticide or pesticides are used widely and very frequently in commercial agriculture and have enabled an enormous increase in crop yields and product quality which ultimately increased the ease to farmers in term of economic advantage as well as ease of farming activities.
There are many combinations of insecticide along with fungicides known in the art for the control of soil borne pests. For example, EP3300602B1 relates to a pesticidal mixture comprising as active compounds at least one pyrazole compound and at least one further pesticide. Furthermore, the invention relates to methods of applying said mixture. The patent further relates to the afidopyropen along with triazole fungicides and insecticides.
US20190104736 a pesticide composition intended for protecting plants, crops or seeds against fungal diseases or insect damages, and the corresponding methods of protection by application of the said composition. More precisely, the subject of the present invention is a pesticide composition comprising flonicamid and a fungicide or an insecticide active substance compounds like chlorantraniliprole and cyantraniliprole.
EP3300602B1 relates to a pesticidal mixture comprising as active compounds at least one pyrazole compound and at least one further pesticide. Furthermore, the invention relates to methods of applying said mixture. The patent further relates to pesticidal mixture comprisies of pyrifluquinazon along with other insecticides and fungicides.
There is however a need for improvement of these combinations. Single active combinations used over a long period of time has resulted in resistance. With the onset of resistance to certain pests, there is a need in the art for a combination of actives that decreases chances of resistance and improves the spectrum of disease and pest control.
However still there is a need for a composition comprises an insecticide selected from the class of chordotonal organs modulators or mixture thereof; a fungicide selected from the class of triazoles; and at least one insecticide selected from various class with different mode of action or mixture thereof which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.
In general use, the pesticide actives are used in the form of a dilute aqueous composition because it can attain a good interaction with the target organism, such as plants, fungi and insects. However, most active pesticide compounds that are used as pesticides are only sparingly or even insoluble in water. The low solubility of such compounds present the challenges and difficulties to formulator in formulating pesticide compounds in stable formulations that can be easily stored for a long time and which still have a high stability and effective activity until end use. This problem especially occurs and may get worsen if more than one active compound is present in the composition.
Therefore, one object of the present invention is to provide improved combinations of insecticides and fungicides for the control of foliar feeder and soil born pests. Another object of the present invention is to provide a method and a composition for controlling insect and fungal pests.
Yet another object of the present invention is to provide improved combinations of insecticides and fungicide that promote plant health and to increase plant or crop yield.
Embodiment of the present invention can ameliorate one or more of the above mentioned problems.

Inventors of the present invention have surprisingly found that the novel synergistic
pesticidal composition of an insecticide selected from the class of chordotonal organs modulators or mixture thereof; a fungicide selected from the class of triazoles; and at least one insecticide selected from various class with different mode of action or mixture thereof as described herein which can provide solution to the above mentioned problems.

SUMMARY OF THE INVENTION
Therefore an aspect of the present invention provides a synergistic pesticidal compositions comprising bioactive amounts of (A) an insecticide selected from the class of chordotonal organs modulators or mixture thereof; (B) a fungicide selected from the class of triazoles; (C) at least one insecticide selected from various class with different mode of action or mixture thereof; and (D) formulation excipients.
Further aspect of the present invention provides a synergistic pesticidal composition comprising bioactive amounts of (A) an insecticide from the class of chordotonal organs modulators selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon or mixture thereof; (B) A fungicide from the class of triazole selected from cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole or tricyclazole or mixture thereof; (C) at least one more insecticide selected from the class of carbamates, organophosphates, phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, mectins, juvenile hormone mimics, mite growth inhibitors, microbial disruptors of insect midgut membrane, inhibitors of mitochondrial ATP synthase, uncouplers of oxidative phosphorylation, nereis toxin, chitin biosynthesis inhibitors, inhibitors of the chitin biosynthesis type 1, moulting disruptors, ecdyson receptor agonists, octopamin receptor agonists, METI (mitochondrial electron transport inhibitors, voltage-dependent sodium channel blockers, tetronic and tetramic acid derivatives, diamides, metadiamides, isoxazolines, from baculoviruses or from the compounds of unknown or uncertain mode of action or from the mixture thereof.
Accordingly, in a further aspect, the present invention provides a method of protecting a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time against pathogenic damage or pest damage by applying to the plant propagation material a composition comprising a pesticidal composition defined in the first aspect.
As per one embodiment formulation for the pesticidal composition is selected from Capsule suspension (CS), Dispersible concentrate (DC), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion, oil in water (EW), Jambo balls or bags (bags in water soluble pouch), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (SC), Suspo-emulsion (SE), Soluble concentrate (SL), Water dispersible granule (WG or WDG), Water soluble granule (SG), Water soluble powder (SP), Wettable powder (WP), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), A mixed formulation of CS and EW (ZW), Granule (GR) / Soil Applied Granules (SAG), Controlled release granules (CR); and and one or more customary formulation adjuvants such as a) dispersant b) wetting agent c) anti-foaming agent d) biocides e) anti-freezing agent f) suspending agent g) thickener h) coating agent and i) buffering agent.
The remainder of the aqueous formulation is preferably wholly water but may comprise other materials, such as inorganic salts. The formulation is preferably, completely free from organic solvents.
Accordingly, in a first aspect, the present invention provides a synergistic pesticidal compositions comprising bioactive amounts of (A) an insecticide from the class of chordotonal organs modulators selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon or mixture thereof; (B) A fungicide from the class of triazole selected from cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole or tricyclazole or mixture thereof; (C) at least one more insecticide selected from the class of carbamates, organophosphates, phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, mectins, juvenile hormone mimics, mite growth inhibitors, microbial disruptors of insect midgut membrane, inhibitors of mitochondrial ATP synthase, uncouplers of oxidative phosphorylation, nereis toxin, chitin biosynthesis inhibitors, inhibitors of the chitin biosynthesis type 1, moulting disruptors, ecdyson receptor agonists, octopamin receptor agonists, METI (mitochondrial electron transport inhibitors, voltage-dependent sodium channel blockers, tetronic and tetramic acid derivatives, diamides, metadiamides, isoxazolines, from baculoviruses or from the compounds of unknown or uncertain mode of action or from the mixture thereof; and one or more customary formulation adjuvants; shows synergistic activity.

DETAILED DESCRIPTION OF THE INVENTION:

The term "synergistic", as used herein, refers the combined action of two or more active
agents blended together and administered conjointly that is greater than the sum of their
individual effects.
"Bioactive amounts” as mentioned herein means that amount which, when applied treatment of crops, is sufficient to effect such treatment.
Therefore an aspect of the present invention provides a synergistic pesticidal compositions comprising bioactive amounts of (A) an insecticide selected from the class of chordotonal organs modulators or mixture thereof; (B) a fungicide selected from the class of triazoles; (C) at least one insecticide selected from various class with different mode of action or mixture thereof.
More particularly, a further aspect of the present invention provides a synergistic pesticidal composition comprising bioactive amounts of (A) an insecticide from the class of chordotonal organs modulators selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon or mixture thereof; (B) A fungicide from the class of triazole selected from cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole or tricyclazole or mixture thereof; (C) at least one more insecticide selected from the class of carbamates, organophosphates, phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, mectins, juvenile hormone mimics, mite growth inhibitors, microbial disruptors of insect midgut membrane, inhibitors of mitochondrial ATP synthase, uncouplers of oxidative phosphorylation, nereis toxin, chitin biosynthesis inhibitors, inhibitors of the chitin biosynthesis type 1, moulting disruptors, ecdyson receptor agonists, octopamin receptor agonists, METI (mitochondrial electron transport inhibitors, voltage-dependent sodium channel blockers, tetronic and tetramic acid derivatives, diamides, metadiamides, isoxazolines, from baculoviruses or from the compounds of unknown or uncertain mode of action or from the mixture thereof.
In an embodiment of the present invention an Insecticide from the class of chordotonal organs modulators is selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon.
In an embodiment of the present invention a fungicide from the class of triazoles is selected from cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole or tricyclazole.
In an embodiment of the present invention an Insecticide from the class of carbamates is selected from carbaryl, carbofuran, carbosulfan, methomyl, oxamyl, pirimicarb, thiodicarb.
In an embodiment of the present invention an Insecticide from the class of organophosphates is selected from acephate, cadusafos, chlorpyrifos, chlorpyrifos-methyl, demeton-S-methyl, dimethoate, ethion, fenamiphos, fenitrothion, fenthion, fosthiazate, methamidophos, monocrotophos, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosphamidon, profenofos, quinalphos, triazophos.
In an embodiment of the present invention an Insecticide from the class of Phenylpyrazole is selected from ethiprole, fipronil, flufiprole, nicofluprole, pyrafluprole, or pyriprole.
In an embodiment of the present invention an Insecticide from the class of pyrethroids is selected from bifenthrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, fenpropathrin, fenvalerate, tau-fluvalinate, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin.
In an embodiment of the present invention an Insecticide from the class of nicotinic insecticides such as Neonicotinoids is selected from acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, flupyrimin, cycloxaprid, paichongding, guadipyr, cycloxylidin; Sulfoximines like sulfoxaflor; Butenolides like flupyradifurone; Mesoionics like triflumezopyrim, dichloromezotiaz.
In an embodiment of the present invention an Insecticide from the class of spinosyns is selected from spinosad, spinetoram.
In an embodiment of the present invention an Insecticide from the class of mectins is selected from abamectin, emamectin benzoate, ivermectin, lepimectin; Milbemycins like milbemectin.
In an embodiment of the present invention an Insecticide from the class of juvenile hormone mimics is selected from hydroprene, kinoprene, methoprene, fenoxycarb, pyriproxyfen.
In an embodiment of the present invention an Insecticide from the class of mite growth inhibitors is selected from clofentezine, hexythiazox, diflovidazin or etoxazole.
In an embodiment of the present invention an Insecticide from the class of microbial disruptors of insect midgut membrane is selected from Bacillus thuringiensis and insecticidal proteins and their by-products.
In an embodiment of the present invention an Insecticide from the class of inhibitors of mitochondrial ATP synthase is selected from diafenthiuron, azocyclotin, cyhexatin, fenbutatin oxide, propargite, or tetradifon.
In an embodiment of the present invention an Insecticide from the class of uncouplers of oxidative phosphorylation is selected from chlorfenapyr, DNOC, or sulfluramid.
In an embodiment of the present invention an Insecticide from the class of nereis toxin is selected from bensultap, monosultap, cartap hydrochloride, thiocyclam, thiocyclam hydrogen oxalate, thiocyclam hydrochloride, thiosultap sodium.
In an embodiment of the present invention an Insecticide from the class of chitin biosynthesis inhibitors is selected from Benzoylureas-bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, triflumuron.
In an embodiment of the present invention an Insecticide from the class of inhibitors of the chitin biosynthesis type-1 is buprofezin.
In an embodiment of the present invention an Insecticide from the class of moulting disruptors is cyromazine.
In an embodiment of the present invention an Insecticide from the class of ecdyson receptor agonists is selected from diacylhydrazines like methoxyfenozide, tebufenozide, halofenozide, fufenozide or chromafenozide.
In an embodiment of the present invention an Insecticide from the class of octopamin receptor agonists is amitraz.
In an embodiment of the present invention an Insecticide from the class of METI (mitochondrial electron transport inhibitors) is selected from fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad, flufenerim, rotenone, cyenopyrafen, cyflumetofen, pyflubumidemm, hydramethylnon, acequinocyl, flometoquin, fluacrypyrim, pyriminostrobin or bifenazate.
In an embodiment of the present invention an Insecticide from the class of voltage-dependent sodium channel blockers is selected from oxadiazines like indoxacarb, semicarbazones like metaflumizone.
In an embodiment of the present invention an Insecticide from the class of inhibitors of the lipid synthesis, inhibitors of acetyl CoA carboxylase (Tetronic and tetramic acid derivatives) is selected from spirodiclofen, spiromesifen, spirotetramat or spiropidion.
In an embodiment of the present invention an Insecticide from the class of diamide is selected from chlorantraniliprole, cyantraniliprole, cyclaniliprole, cyhalodiamide, cyproflanilide, flubendiamide, tetraniliprole, tetrachlorantraniliprole, tyclopyrazoflor.
In an embodiment of the present invention an Insecticide from the class of metadiamide is broflanilide.
In an embodiment of the present invention an Insecticide from the class of Isoxazolines is selected from fluxametamide, isocycloseram.
In an embodiment of the present invention an Insecticide from the class of Baculoviruses is selected from Granuloviruses and Nucleopolyhedrosis viruses.
In an embodiment of the present invention an Insecticide from the class of compounds of unknown or uncertain mode of action is selected from azadirechtin, benzpyrimoxan (insect growth regulators), pyridalyl, oxazosulfyl, dimpropyridaz (pyrazole carboxamide insecticide), fluhexafon, acaricidal compounds-cyetpyrafen, flupentiofenox, acynonapyr; nematicidal compounds-cyclobutrifluram, fluazaindolizine, or tioxazafen.
Chordotonal organ modulators:
Afidopyropen interferes with the chordotonal organ of the insect, which causes insects to lose their reaction to gravity, balance, sound, position and movement, resulting in epicophosis and loss of direction, further leading to food and water loss, and thus causes insect deaths from hunger.
Afidopyropen effectively reduces viral and bacterial diseases transmitted by insect vector, being very effective in the control of aphid and whitefly, with a long-lasting effect. It is also effective against different stages of insects (ineffective to ovum). It has an outstanding foliar infiltration capacity, and is resistant to rain wash due to its unique formulation.
Flonicamid exhibits excellent aphicidal activity and also shows good insecticidal activity against other sucking insect pests such as thrips, white ies, planthoppers, leafhoppers, plant bugs, and mealybugs in fruit trees, cereals, rice, potatoes, cotton, vegetables and ornamentals. Flonicamid soil applications also provide control of the foliar pests mentioned above. Flonicamid rapidly inhibits the feeding behavior of aphids, and has better action through ingestion than by contact. Its mode of action is different from other insecticides such as neonicotinoids, pymetrozine and pyri uquinazon. Flonicamid belongs to IRAC Group 29 and is the only insecticide in this class.
Pymetrozine is a new insecticide, highly active and specific against sucking insect pests. Pymetrozine is the only representative of the pyridine azomethines, a new class of insecticides, and is currently being developed worldwide for control of aphids and whiteflies in field crops, vegetables, ornamentals, cotton, hop, deciduous fruit, and citrus, and of the brown planthopper, Nilaparvata lugens (Staol), in rice. The compound appears to have great promise in integrated pest management (IPM) programs due to its high degree of selectivity, low mammalian toxicity, and safety to birds, fish, and non-target arthropods.
Pyrifluquinazon is a recently commercialized insecticide that interferes with chordotonal receptor neuron function. Eggs, first-instar nymphs, and mid-instar nymphs of Bemisia tabaci Middle East Asia Minor 1 (Gennadius) (Hemiptera: Aleyrodidae) were treated on cotton leaves with 0.057 g. ai. /liter Pyrifluquinazon 20 SC in a growth room study. When 5-d-old eggs were treated, there was essentially no survival among emerging crawlers. When crawlers and first instars were treated, survival and development to subsequent instars was drastically reduced compared with the untreated control. Treatment of mid instars had no effect on mortality.
Triazole Fungicide:
Difenoconazole is a broad spectrum fungicide that controls a wide variety of fungi – including members of the Aschomycetes, Basidomycetes and Deuteromycetes families. It acts as a seed treatment, foliar spray and systemic fungicide. It is taken up through the surface of the infected plant and is translocated to all parts of the plant. It has a curative effect and a preventative effect. Difenoconazole can be applied to winter wheat, oilseed rape, Brussels sprouts, cabbage, broccoli/calabrese and cauliflower. It controls various fungi including Septoria tritici, Brown Rust, Light Leaf Spot, Leaf Spot, Pod Spot, Ring Spot and Stem canker. It also prevents Ear Discolouration in winter wheat. The mode of action of difenoconazole is that it is a sterol demethylation inhibitor which prevents the development of the fungus by inhibiting cell membrane ergosterol biosynthesis.
Tebuconazole is a broad spectrum systemic Triazole fungicide with protective, curative and eradicative mode of action. It is effective against wide range of diseases. It is very effective against brown rust, leaf blotch, Net blotch, septoria leaf spot& Yellow rust of cereals; Soybean-Asian rust, brown spot/Septoria leaf spot, Powdery mildew; Rice-Dirty panicle & grain discoloration.
Prothioconazole is a synthetic compound of the triazolinthione family of compounds. It is a broad spectrum systemic fungicide, with curative, preventative and eradicative action. It can be used as both a seed treatment and a foliar treatment. After absorption it moves into cells of the target organisms, effecting sterol biosynthesis and thereby disrupting membrane structure. This ultimately effects hyphal growth and germ tube elongation. Fungi susceptible to prothioconazole include early leaf spot (Mycosphaerella arachidis), eyespot, Fusarium spp., powdery mildew, net blotch, phoma leaf spot, Rhynchosporium secalis, Sclerotinia sclerotiorum, Sclerotium rolfsii, Septoria tritici, Septoria nodorum, rust and tan spot. Prothioconazole is approved for use on barley, durum wheat, oats, oilseed rape (winter), rye (winter), and wheat.
Pyrethroids class of insecticides:
Lambda-cyhalothrin belongs to a group of chemicals called pyrethroids. Pyrethroids are manmade chemicals that are similar to the natural insecticides pyrethrins. Scientists developed pyrethroid insecticides to have properties better than those of the pyrethrins. Pyrethroids, including lambda-cyhalothrin, disrupt the normal functioning of the nervous system in an organism. By disrupting the nervous system of insects, lambda-cyhalothrin may cause paralysis or death. Temperature influences insect paralysis and the toxicity of lambda-cyhalothrin.
Nicotinic group of Insecticides:
Thiamethoxam is a broad-spectrum, systemic insecticide, which means it is absorbed quickly by plants and transported to all of its parts, including pollen, where it acts to deter insect feeding. An insect can absorb it in its stomach after feeding, or through direct contact, including through its tracheal system. The compound gets in the way of information transfer between nerve cells by interfering with nicotinic acetylcholine receptors in the central nervous system, and eventually paralyzes the muscles of the insects.
Triflumezopyrim, a newly commercialized molecule belongs to the novel class of mesoionic insecticides. Triflumezopyrim is an extremely effective hopper insecticide with low impact on non-target organisms including pollinators. This unique class of mesoionic chemistry targets the nicotinic acetylcholine receptor, inducing a physiological action which is distinct from that of neonicotinoids.
Dichloromezotiaz, a novel class of mesoionic compounds has been discovered, with exceptional insecticidal activity on a range of Hemiptera and Lepidoptera. These compounds bind to the orthosteric site of the nicotinic acetylcholine receptor and result in a highly potent inhibitory action at the receptor with minimal agonism. The synthesis, biological activity, optimization and mode of action will be discussed. Dicloromezotiaz can provide a useful control tool for lepidopteran pests, with an underexploited mode of action among these pests.
Mectin group of Insecticide:
Emamectin benzoate is widely used in controlling lepidopterous pests (order of insects that as larvae are caterpillars and as adults have four broad wings including butterflies, moths, and skippers) in agricultural produce. The low-application rate of the active ingredient needed (~6 g/acre) and broad-spectrum applicability as an insecticide has gained emamectin significant popularity among farmers. Emamectin has been shown to possess a greater ability to reduce the colonization success of engraver beetles and associated wood borers in loblolly pines (Pinus taeda L).
Pyriproxyfen is a pesticide which is found to be effective against a variety of insects. It was introduced to the US in 1996, to protect cotton crops against whitefly. It has also been found useful for protecting other crops. It is also used as prevention against flea control on household pets, for killing indoor and outdoor ants and roaches. Methods of application include aerosols, bait, carpet powders, foggers, shampoos and pet collars. Pyriproxyfen is a juvenile hormone analog and an insect growth regulator. It prevents larvae from developing into adulthood and thus rendering them unable to reproduce.
Inhibitors of mitochondrial ATP synthase:
Diafenthiuron is an aromatic ether that is 1,3-diisopropyl-5-phenoxybenzene in which the hydrogen atom at position 2 is substituted by a (tert-butylcarbamothioyl)nitrilo group. An agricultural proinsecticide which is used to control mites, aphids and whitefly in cotton.
Diamide group of insecticides:
Cyantraniliprole is an insecticide of the ryanoid class. Cyantraniliprole is highly toxic to bees. It is a new second-generation ryanodine receptor insecticide whose pesticidal mode of action is through unregulated activation of insect ryanodine receptor channels, which leads to internal calcium store depletion and impaired regulation of muscle contraction, causing paralysis and eventual death of the insect. Cyantraniliprole is used to control insect pests in fruit crops, tree nuts, oil seed crops, cotton, grapes, rice, vegetables, ornamentals and turf around the world.
Compounds of unknown or uncertain mode of action:
Dimpropyridaz, chemically is a pyrazole carboxamide insecticide that has a pyridin-3-yl group, as in tyclopyrazoflor. Dimpropyridaz is effective against aphids. Dimpropyridaz mechanism of action is unknown.
Benzpyrimoxan has a unique chemical structure which contains benzyloxy and cyclic acetal groups on pyrimidine moiety (5-(1,3-dioxan-2-yl)-4-[4 (trifluoro methyl)benzyloxy]pyrimidine). Benzpyrimoxan has high activity against nymphal stages of rice plant hoppers without any adulticidal activity. It provides excellent and long lasting control against rice plant hoppers, including populations that have developed resistance to several other chemical groups of insecticide.
The present inventors believe that the combination of the present invention surprisingly results in a synergistic action. The combination of the present invention allows for a broad spectrum of pest control and has surprisingly improved plant vigour and yield. The broad spectrum of the present combination also provides a solution for preventing the development of resistance.
The synergistic agrochemical composition has advantageous curative, preventive and systemic pesticidal properties for protecting cultivated plants. As has been mentioned, said active ingredient composition can be used to inhibit or destroy the pathogens that occur on plants or parts of plants of different crops or useful plants. The synergistic agrochemical composition of specific active ingredient has the special advantage of being highly active against fungal diseases and insect pests.The present inventors believe that the combination of the present invention surprisingly results in a synergistic action. The combinations of the present invention allow for a broad spectrum of pest control and has surprisingly improved plant vigour and yield. The broad spectrum of the present combination also provides a solution for preventing the development of resistance.
The synergistic composition has very advantageous curative, preventive and systemic pesticidal properties for protecting cultivated plants. As has been mentioned, said active ingredient composition can be used to inhibit or destroy the pathogens that occur on plants or parts of plants (fruit, blossoms, leaves, stems, tubers, roots) of different crops or useful plants, while at the same time those parts of plants which grow later are also protected from attack by such pathogens. Active ingredient composition has the special advantage of being highly active against diseases in the soil that mostly occur in the early stages of plant development.
The synergistic composition of pesticide are used to protect the crops and plants from insect and fungal pests. The lists of the major crops includes but are not limited to GMO (Genetically Modified Organism) and Non GMO varieties of Cotton (Gossypium spp.), Paddy (Oryza sativa), Wheat (Triticum aestavum), Barley (Hordeum vulgare), Maize (Zea mays), Sorghum (Sorghum bicolor), Oat (Avena sativa), Pearl millet (Pennisetum glaucum), Sugarcane (Saccharum officinarum) , Sugarbeet (Beta vulgaris), Soybean (Glycin max), Peanut (Arachis hypogaea), Sunflower (Helianthus annuus) , Mustard (Brassica juncea), Rape seed (Brassica napus), Linseed (Linum usitatissimum), Sesame (Sesamum indicum), Green gram (Vigna radiata), Black gram (Vigna mungo), Chickpea (Cicer aritinum), Cowpea (Vigna unguiculata), Redgram (Cajanus cajan), Frenchbean (Phaseolus vulgaris), Indian bean (Lablab purpureus), Horse gram (Macrotyloma uniflorum), Field pea (Pisum sativum), Cluster bean (Cyamopsis tetragonoloba), Lentils (Lens culinaris), Brinjal (Solanum melongena), Cabbage (Brassica oleracea var. capitata), Cauliflower (Brassica oleracea var. botrytis), Okra (Abelmoschus esculentus) , Onion (Allium cepa L.), Tomato (Solanum lycopersicun) , Potato (Solanum tuberosum) , Sweet potato (Ipomoea batatas), Chilly (Capsicum annum), Garlic (Allium sativum), Cucumber (Cucumis sativus), Muskmelons (Cucumis melo), Watermelon (Citrullus lanatus), Bottle gourd (Lagenaria siceraria), Bitter gourd (Momordica charantia), Radish (Raphanus sativus), Carrot (Dacus carota subsp. sativus), Turnip (Brassica rapa subsp rapa), Apple (Melus domestica), Banana (Musa spp.), Citrus groups (Citrus spp.), Grape (Vitis vinifera), Guava (Psidium guajava), Litchi (Litchi chinensis), Mango (Mangifera indica), Papaya (Carica papaya), Pineapple (Ananas comosus), Pomegranate (Punica granatum) , Sapota (Manilkara zapota), Tea (Camellia sinensis), Coffea (Coffea Arabica), Turmeric (Curcuma longa), Ginger (Zingiber officinale), Cumin (Cuminum cyminum), Fenugreek (Trigonella foenum-graecum), Fennel (Foeniculum vulgare), Coriander (Coriandrum sativum), Ajwain (Trachyspermum ammi), Psyllium (Plantago ovate), Black Pepper (Piper nigrum), Stevia (Stevia rebaudiana), Safed musli (Chlorophytum tuberosum), Drum stick (Moringa oleifera), Coconut (Coco nucifera), Mentha ( Mentha spp.), Rose (Rosa spp.), Jasmine (Jasminum spp.), Marigold ( Tagetes spp.), Common daisy (Bellis perennis), Dahlia (Dahlia hortnesis), Gerbera ( Gerbera jamesonii), Carnation (Dianthus caryophyllus), vegetables: solanaceous vegetables such as eggplant, tomato, pimento, pepper, potato, etc., cucurbit vegetables such as cucumber, pumpkin, zucchini, water melon, melon, squash, etc., cruciferous vegetables such as radish, white turnip, horseradish, kohlrabi, Chinese cabbage, cabbage, leaf mustard, broccoli, cauliflower, etc., asteraceous vegetables such as burdock, crown daisy, artichoke, lettuce, etc, liliaceous vegetables such as green onion, onion, garlic, and asparagus, ammiaceous vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceous vegetables such as spinach, Swiss chard, etc., lamiaceous vegetables such as Perilla frutescens, mint, basil, etc, strawberry, sweet potato, Dioscorea japonica, colocasia, etc., flowers, foliage plants, turf grasses, fruits: pome fruits such apple, pear, quince, etc, stone fleshy fruits such as peach, plum, nectarine, Prunus mume, cherry fruit, apricot, prune, etc., citrus fruits such as orange, lemon, rime, grapefruit, etc., nuts such as chestnuts, walnuts, hazelnuts, almond, pistachio, cashew nuts, macadamia nuts, etc. berries such as blueberry, cranberry, blackberry, raspberry, etc., grape, kaki fruit, olive, plum, banana, coffee, date palm, coconuts, etc. , trees other than fruit trees; tea, mulberry, flowering plant, trees such as ash, birch, dogwood, Eucalyptus, Ginkgo biloba, lilac, maple, Quercus, poplar, Judas tree, Liquidambar formosana, plane tree, zelkova, Japanese arborvitae, fir wood, hemlock, juniper, Pinus, Picea, and Taxus cuspidate, etc.
The synergistic combination of the present invention used to control the insects-pests and plant parasitic nematode. The major insects pests are belongs to the order Hemiptera, for example, rice leafhopper Nephotettix nigropictus, rice brown plant hopper Nilaparvata lugen, rice white backed plant hopper, Apple Mealy bug Phenococcus aceris, bean aphid Aphis fabae, black citrus aphid Toxoptera aurantii, citrus black scale Saissetia oleae, cabbage aphid Brevicoryne brassicae, Lipaphis erysimi, citrus red scale Aonidiella aurantii, yellow scale Aonidiella citrine, citrus mealybug Planococcus citri, corn leaf aphid Rhopalosiphum maidis, cotton aphid Aphis gossypii, cotton jassid Amrasca biguttula biguttla, cotton mealy bug Planococcus spp. And Pseudococcus spp., cotton stainer Dysdercus suturellus, cotton whitefly Bemisia tabaci, cowpea aphid Aphis crassivora, grain aphid Sitobion avenae, golden glow aphid Uroleucon spp., grape mealybug Pseudococcus maritimus, green peach aphid Myzus persicae, greenhouse whitefly Trialeurodes vaporariorum, papaya mealy bug Pracoccus marginatus, pea aphid Acyrthosiphon pisum, sugarcane mealybug Saccharicoccus sacchari, potato aphid Myzus persicae, potato leaf hopper Empoasca fabae, cotton whitefly Bemisia tabaci, tarnished plant bug Lygus lineolaris, wooly apple aphid Eriosoma lanigerum, mango hopper Amritodus atkinsoni, Idioscopus spp. ; order Lepidoptera, army worm Mythimna unipuncta, asiatic rice borer Chilo suppressalis, bean pod borer Maruca vitrata, beet armyworm Spodoptera exigua, black cutworm Agrotis ipsilon, bollworm Helicoverpa armigera , cabbage looper Trichoplusia ni, codling moth Cydia pomonella, croton caterpillar Achea janata, diamond backmoth Plutella xylostella, cabbage worm Pieris rapae, pink bollworm Pectinophora gossypiella, sugarcane borer Diatraea saccharalis, tobacco budworm Heliothis virescens, tomato fruitworm Helicoverpa zea, velvet bean caterpillar Anticarsia gemmatalis, yellow stem borer Scirpophaga incertulas, spotted bollworm Earias vittella, rice leaffolder Cnaphalocrocis medinalis, pink stem borer Sesamia spp., tobacco leafeating caterpillar Spodoptera litura; brinjal fruit and shoot borer Leucinodes orbonalis, bean pod borer Maruca vitrata, Maruca testulalis, armyworm Mythimna separata, cotton pinkbollworm Pectinophora gossypiella, citrus leafminer Phyllocnistis citrella, cabbage butterfly Pieris bras-sicae, diamond backmoth Plutella xylostella, paddy stem borer Scirpophaga excerptallis, Scirpophaga incertulas, Scirpophaga innotata, wheat stem borer Sesamia inferens, Sitotroga cerealella, Spilosoma obliqua, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Trichoplusia ni, Tryporyza novella, Tuta absoluta.
from the order Coleoptera, for example, apple twig borer Amphicerus spp., corn root worm Diabrotica virgifera, cucumber beetle diabrotica balteata, boll weevil Anthonomus grandis, grape flea beetle Altica chalybea, grape root worm Fidia viticola, grape trunk borer Clytoleptus albofasciatus, radish flea beetle Phyllotreta armoraciae, maize weevil Sitophilus zeamais, northern corn rootworm Diabrotica barberi, rice water weevil Lissorhoptrus oryzophilus, Anthonomus grandis, Bruchus lentis, Diabrotica semipunctata, Diabrotica virgifera, Dicladispa armigera, Epila-chna varivestis, various species of white grubs are Holotrichia bicolor, Holotrichia consanguinea, Holotrichia serrata, Leptinotarsa decemlineata, Phyllotreta chrysocephala, Popillia japonica etc; from the order Orthoptera, for example, Gryllotalpa spp., Locusta spp., and Schistocerca is spp.; from the order Thysanoptera, for example, Frankliniella spp., Thrips palmi, Thrips tabaci and Scirtothrips dorsalis; termites (Isoptera), e.g. Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Leucotermes flavipes, Microtermes obesi, Odontotermes obesus, Reticulitermes flavipes, Termes natalensis; from the order Heteroptera, for example, Dysdercus spp., Leptocorisa spp., from the order Hymenoptera, for example, Solenopsis spp. ; from the order Diptera, for example, Antherigona soccata, Dacus spp., Liriomyza spp., Melanagromyza spp., from the order Acarina, for example, Aceria mangiferae, Brevipalpus spp., Eriophyes spp., Oligonychus mangiferus, Oligonychus punicae, Panonychus citri, Panonychus ulmi, Polyphagotarsonemus latus, Tarsonemus spp., Tetranychus urticae, Tetranychus cinnabarinus;
The mixtures according to the invention can be applied to any and all developmental stages of pests, such as egg, larva, pupa, and adult. The pests may be controlled by contacting the target pest, its food supply, habitat, breeding ground or its locus with a pesticidally effective amount of the inventive mixtures or of compositions comprising the mixtures.
The compositions according to the present invention is also effective for controlling the following fungal and bacterial plant diseases:
Disease in rice: Blast (Magnaporthe grisea), Helminthosporium leaf spot (Cochliobolus miyabeanus), sheath blight (Rhizoctonia solani), bakanae disease (Gibberella fujikuroi) and grain discoloration (dirty panicles caused by Alternaria spp., Curvularia spp., Drechslera spp., Fusarium spp., Phoma spp. Etc.)
Diseases in wheat: powdery mildew (Erysiphe graminis) , Fusariuin head blight (Fusarium graminearum, F. avenacerum, F. culmorum, Microdochium nivale) , rust (Puccinia striiformis, P. graminis, P. recondita) , pink snow mold (Micronectriella nivale), Typhula snow blight (Typhula sp . ) , loose smut (Ustilago tritici) , bunt (Tilletia caries) , eyespot (Pseudocercosporella herpotrichoides) , leaf blotch (Mycosphaerella graminicola) , glume blotch (Stagonospora nodorum), septoria, and yellow spot (Pyrenophora tritici-repentis) .
Diseases of barley: powdery mildew (Erysiphe graminis), Fusarium head blight (Fusarium graminearum, F. avenacerum, F. culmorum, Microdochium nivale), rust (Puccinia striiformis, P. graminis, P. hordei), loose smut (Ustilago nuda), scald (Rhynchosporium secalis), net blotch (Pyrenophora teres), spot blotch (Cochliobolus sativus), leaf stripe (Pyrenophora graminea), and Rhizoctonia damping-off (Rhizoctonia solani).
Diseases in corn: smut (Ustilago maydis), brown spot (Cochliobolus heterostrophus), copper spot (Gloeocercospora sorghi), southern rust (Puccinia polysora), gray leaf spot (Cercospora zeae-maydis), white spot (Phaeosphaeria mydis and/or Pantoea ananatis) and Rhizoctonia damping-off (Rhizoctonia solani).
Diseases of citrus: melanose (Diaporthe citri), scab (Elsinoe fawcetti), penicillium rot (Penicillium digitatum, P. italicum), and brown rot (Phytophthora parasitica, Phytophthora citrophthora).
Diseases of apple: blossom blight (Monilinia mali), canker (Valsa ceratosperma), powdery mildew (Podosphaera leucotricha), Alternaria leaf spot (Alternaria alternata apple pathotype), scab (Venturia inaequalis), powdery mildew, bitter rot (Colletotrichum acutatum), crown rot (Phytophtora cactorum), blotch (Diplocarpon mali), and ring rot (Botryosphaeria berengeriana).
Diseases of pear: scab (Venturia nashicola, V. pirina), powdery mildew, black spot (Alternaria alternata Japanese pear pathotype), rust (Gymnosporangium haraeanum), and phytophthora fruit rot (Phytophtora cactorum).
Diseases of peach: brown rot (Monilinia fructicola), powdery mildew, scab (Cladosporium carpophilum), and phomopsis rot (Phomopsis sp.).
Diseases of grape: anthracnose (Elsinoe ampelina), ripe rot (Glomerella cingulata), powdery mildew (Uncinula necator), rust (Phakopsora ampelopsidis), black rot (Guignardia bidwellii), botrytis, and downy mildew (Plasmopara viticola).
Diseases of Japanese persimmon: anthracnose (Gloeosporium kaki), and leaf spot (Cercospora kaki, Mycosphaerella nawae).
Diseases of gourd: anthracnose (Colletotrichum lagenarium), powdery mildew (Sphaerotheca fuliginea), gummy stem blight (Mycosphaerella melonis), Fusarium wilt (Fusarium oxysporum), downy mildew (Pseudoperonospora cubensis), Phytophthora rot (Phytophthora sp.), and damping-off (Pythium sp.).
Diseases of tomato: early blight (Alternaria solani), leaf mold (Cladosporium fulvum), and late blight (Phytophthora infestans).
Diseases of eggplant: brown spot (Phomopsis vexans), and powdery mildew (Erysiphe cichoracearum) Diseases of cruciferous vegetables: Alternaria leaf spot (Alternaria japonica), white spot (Cercosporella brassicae), clubroot (Plasmodiophora brassicae), and downy mildew (Peronospora parasitica).
Diseases of onion: rust (Puccinia allii), and downy mildew (Peronospora destructor).
Diseases of soybean: purple seed stain (Cercospora kikuchii), sphaceloma scad (Elsinoe glycines), pod and stem blight (Diaporthe phaseolorum var. sojae), septoria brown spot (Septoria glycines), frogeye leaf spot (Cercospora sojina), rust (Phakopsora pachyrhizi) Yellow rust, brown stem rot (Phytophthora sojae), and Rhizoctonia damping-off (Rhizoctonia solani).
Diseases of kidney bean: anthracnose (Colletotrichum lindemthianum). Diseases of peanut: leaf spot (Cercospora personata), brown leaf spot (Cercospora arachidicola) and southern blight (Sclerotium rolfsii).
Diseases of garden pea: powdery mildew (Erysiphe pisi), and root rot (Fusarium solani f. sp. pisi).
Diseases of potato: early blight (Alternaria solani), late blight (Phytophthora infestans), pink rot (Phytophthora erythroseptica), and powdery scab (Spongospora subterranean f. sp. subterranea).
Diseases of strawberry: powdery mildew (Sphaerotheca humuli), and anthracnose (Glomerella cingulata).
Diseases of tea: net blister blight (Exobasidium reticulatum), white scab (Elsinoe leucospila), gray blight (Pestalotiopsis sp.), and anthracnose (Colletotrichum theae-sinensis).
Diseases of tobacco: brown spot (Alternaria longipes), powdery mildew (Erysiphe cichoracearum), anthracnose (Colletotrichum tabacum), downy mildew (Peronospora tabacina), and black shank (Phytophthora nicotianae).
Diseases of rapeseed: sclerotinia rot (Sclerotinia sclerotiorum), and Rhizoctonia damping-off (Rhizoctonia solani). Diseases of cotton: Rhizoctonia damping-off (Rhizoctonia solani).
Diseases of sugar beat: Cercospora leaf spot (Cercospora beticola), leaf blight (Thanatephorus cucumeris), Root rot (Thanatephorus cucumeris), and Aphanomyces root rot (Aphanomyces cochlioides).
Diseases of rose: black spot (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa), and downy mildew (Peronospora sparsa). Diseases of chrysanthemum and asteraceous plants: downy mildew (Bremia lactucae), leaf blight (Septoria chrysanthemi-indici), and white rust (Puccinia horiana).
Diseases of various groups: diseases caused by Pythium spp. (Pythium aphanidermatum, Pythium debarianum, Pythium graminicola, Pythium irregulare, Pythium ultimum), gray mold. (Botrytis cinerea), and Sclerotinia rot (Sclerotinia sclerotiorum).
Disease of Japanese radish: Alternaria leaf spot (Alternaria brassicicola).
Diseases of turfgrass: dollar spot (Sclerotinia homeocarpa), and brown patch and large patch (Rhizoctonia solani).
Disease of banana: Black sigatoka (Mycosphaerella fijiensis), Yellow sigatoka (Mycosphaerella musicola).
Disease of sunflower: downy mildew (Plasmopara halstedii).
Seed diseases or diseases in the early stages of the growth of various plants caused by Aspergillus spp., Penicillium spp., Fusarium spp., Gibberella spp., Tricoderma spp., Thielaviopsis spp., Rhizopus spp., Mucor spp., Corticium spp., Phoma spp., Rhizoctonia spp. and Diplodia spp.
Viral diseases of various plants mediated by Polymixa spp. or Olpidium spp. and so on.
The term "health of a plant" or "plant health" is defined as a condition of the plant and/or its products. As a result of the improved health, yield, plant vigor, quality and tolerance to abiotic or biotic stress are increased. Noteworthy, the health of a plant when applying the method according to the invention, is increased independently of the pesticidal properties of the active ingredients used because the increase in health is not based upon the reduced disease pressure but instead on complex physiological and metabolic reactions which result for example in an activation of the plant's own natural defense system. As a result, the health of a plant is increased even in the absence of diseases pressure. Accordingly, in an especially preferred embodiment of the method according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. The above identified indicators for the health condition of a plant may be interdependent or they may result from each other. An increase in plant vigor may for example result in an increased yield and/or tolerance to abiotic or biotic stress. One indicator for the condition of the plant is the yield. "Yield" is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits in the proper sense, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and/or processed after harvesting.
In an especially preferred embodiment of the invention, the yield of the treated plant is increased.
In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically.
According to the present invention, "increased yield" of a plant, in particular of an agricultural, silvicultural and/or horticultural plant means that the yield of a product of the respective plant is increased by a measurable amount over the yield of the same product of the plant produced under the same conditions, but without the application of the mixture according to the invention.
Increased yield can be characterized, among others, by the following improved proper-ties of the plant: increased plant, weight, increased plant height, increased biomass such as higher overall fresh weight (FW), increased number of flowers per plant, higher grain yield, more tillers or side shoots (branches), larger leaves, increased shoot growth, increased protein content, increased oil content, increased starch content, increased pigment content, increased leaf are index.
According to the present invention, the yield is increased by at least 5 %, preferable by 5 to 10 %, more preferable by 10 to 20 %, or even 20 to 30 % compared to the untreated control plants or plants treated with pesticides in a way different from the method according to the present invention. In general, the yield increase may even be higher.
A further indicator for the condition of the plant is the plant vigor. The plant vigor becomes manifest in several aspects such as the general visual appearance. In another especially preferred embodiment of the invention, the plant vigor of the treated plant is increased. In another preferred embodiment of the invention, the plant vigor of the plants treated according to the method of the invention, is increased synergistically. Improved plant vigor can be characterized, among others, by the following improved properties of the plant: improved vitality of the plant, improved plant growth, improved plant development, improved visual appearance, improved plant stand (less plant verse/lodging), improved emergence, enhanced root growth and/or more developed root system, enhanced nodulation, in particular rhizobium nodulation, bigger leaf blade, bigger size, increased plant weight, increased plant height, increased tiller number, increased number of side shoots, increased number of flowers per plant, increased shoot growth, increased root growth (extensive root system), increased yield when grown on poor soils or unfavorable climate, enhanced photosynthetic activity (e.g. based on increased stomatal conductance and/or increased CO2 assimilation rate), increased stomatal conductance, increased CO2 assimilation rate, enhanced pigment content (e.g. chlorophyll content), earlier flowering, earlier fruiting, earlier and improved germination, earlier grain maturity, improved self-defense mechanisms, improved stress tolerance and resistance of the plants against biotic and abiotic stress factors such as fungi, bacteria, viruses, heat stress, cold stress, drought stress, UV stress and/or salt stress, less non-productive tillers, less dead basal leaves, less input needed (such as fertilizers or water), greener leaves, complete maturation under shortened vegetation periods, less fertilizers needed, less seeds needed, easier harvesting, faster and more uniform ripening, longer shelf-life, longer panicles, delay of senescence, stronger and/or more productive tillers, better extractability of ingredients, improved quality of seeds (for being seeded in the following seasons for seed production), better nitrogen uptake, improved reproduction, reduced production of ethylene and/or the inhibition of its reception by the plant.
The improvement of the plant vigor according to the present invention particularly means that the improvement of any one or several or all of the above mentioned plant characteristics are improved independently of the pesticidal action of the mixture or active ingredients (components).
Another indicator for the condition of the plant is the "quality" of a plant and/or its products.
In an especially preferred embodiment of the invention, the quality of the treated plant is increased.
In another preferred embodiment of the invention, the quality of the plants treated according to the method of the invention, is increased synergistically.
According to the present invention, enhanced quality means that certain plant characteristics such as the content or composition of certain ingredients are increased or improved by a measurable or noticeable amount over the same factor of the plant produced under the same conditions, but without the application of the mixtures of the present invention. Enhanced quality can be characterized, among others, by following improved properties of the plant or its product: increased nutrient content, increased protein content, increased content of fatty acids, increased metabolite content, increased carotenoid content, increased sugar content, increased amount of essential amino acids, improved nutrient composition, improved protein composition, improved composition of fatty acids, improved metabolite composition, improved carotenoid composition, improved sugar composition, improved amino acids composition, improved or optimal fruit color, improved leaf color, higher storage capacity, higher processability of the harvested products.
Another indicator for the condition of the plant is the plant's tolerance or resistance to biotic and/or abiotic stress factors. Biotic and abiotic stress, especially over longer terms, can have harmful effects on plants. Biotic stress is caused by living organisms while abiotic stress is caused for example by environmental extremes. According to the present invention, "enhanced tolerance or resistance to biotic and/or abiotic stress factors" means (1.) that certain negative factors caused by biotic and/or abiotic stress are diminished in a measurable or noticeable amount as compared to plants exposed to the same conditions, but without being treated with a mixture according to the invention and (2.) that the negative effects are not diminished by a direct action of the mixture according to the invention on the stress factors, e.g. by its fungicidal action which directly destroys the microorganisms or diseases, but rather by a stimulation of the plants' own defensive reactions against said stress factors.
Formulation of the present invention can be in any of the formulations selected from Capsule suspension (CS), Dispersible concentrate (DC), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion, oil in water (EW), Jambo balls or bags (bags in water soluble pouch), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (SC), Suspo-emulsion (SE), Soluble concentrate (SL), Water dispersible granule (WG or WDG), Water soluble granule (SG), Water soluble powder (SP), Wettable powder (WP), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), A mixed formulation of CS and EW (ZW), Granule (GR) / Soil Applied Granules (SAG), Controlled release granules (CR).
One or more of the active ingredients is encapsulated for various purposes, such as to increase the residual biological activity, or to reduce the acute toxicity, or to obtain a physical or chemically stable water-based formulation. The purpose determines whether the “free” active ingredient and the “release rate” are relevant properties of a specific product.
Further pesticidal composition comprising (A) an insecticide selected from the class of chordotonal organs modulators or mixture thereof; (B) a fungicide selected from the class of triazoles; (C) at least one insecticide selected from various class with different mode of action or mixture thereof are present in the said composition in specific fixed ratio.
In further aspect the present invention relates to the synergistic pesticidal composition comprising bioactive amounts of (A) is 0.1 to 30% w/w of the composition; (B) is 0.1 to 40% w/w of the composition; and (C) is 0.1 to 30% w/w of the composition.
Active Ingredients Compound A Compound
B Compound
C
Examples Insecticide(s)
from chordontonal organ modulator Triazole fungicide One more insecticide(s)
% of Active Ingredient
0.1 to 30%
0.1 to 40%
0.1 to 30%
The composition of the present invention in addition to bioactive amounts of active ingredients further comprises inactive excipients including but not limited to dispersant, anti-freezing agent, anti-foam agent, wetting agent, suspension aid, antimicrobial agent, thickener, quick coating agent or sticking agents (also referred to as “stickers” or “binders”) and buffering agent.
A dispersant is a substance which adsorbs onto the surface of particles and helps to preserve the state of dispersion of the particles and prevents them from re-aggregating. Dispersants are added to agrochemical formulations to facilitate dispersion and suspension during manufacture, and to ensure the particles re-disperse into water in a spray tank. They are widely used in wettable powders, suspension concentrates and water-dispersible granules. Surfactants that are used as dispersants have the ability to adsorb strongly onto a particle surface and provide a charged or steric barrier to reaggregation of particles. The most commonly used surfactants are anionic, non-ionic, or mixtures of the two types. For wettable powder formulations, the most common dispersants are sodium lingo sulphonates. For suspension concentrates, very good adsorption and stabilization are obtained using polyelectrolytes, such as sodium naphthalene sulphonate formaldehyde condensates. Tristyrylphenolethoxylate phosphate esters are also used. Nonionics such as alkyl aryl ethylene oxide condensates and EO-PO block copolymers are sometimes combined with anionics as dispersants for suspension concentrates. In recent years, new types of very high molecular weight polymeric surfactants have been developed as dispersants. These have very long hydrophobic ‘backbones’ and a large number of ethylene oxide chains forming the ‘teeth’ of a ‘comb’ surfactant. These high molecular weight polymers can give very good long-term stability to suspension concentrates because the hydrophobic backbones have many anchoring points onto the particle surfaces. Examples of dispersants used for suspension concentrates include, but not limited to, alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium polycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycol ether-phosphate, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide.
Examples of dispersants used for Wettable Granule (WG), WDG (Water Dispersible Granule) formulation include, but not limited to, naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, polyacrylates and phosphate esters, calcium lignosulfonate, lignin sulfonate sodium salt
Examples of dispersants used for Suspo Emulsion (SE) formulation include, but not limited to, polyesters, polyamides, poly- carbonates, polyurea and polyurethanes, acrylic polymers and copolymers, styrene copolymers, butadiene copolymers, polysaccharides such as starch and cellulose derivatives, vinylalcohol, vinylacetate and vinylpyrrolidone polymers and copolymers, polyethers, epoxy, phenolic and melamine resins, polyolefins and define copolymers and mixtures thereof. Examples of preferred polymers are acrylate polymers such as poly(methacrylate), poly(ethyl methacrylate), poly(methylmethacrylate), acrylate copoylmers and styrene-acrylic copolymers as defined herein below, poly(styrene-co maleic anhydride), cellulosic polymers such as ethyl cellulose, cellulose acetate, cellulose acetatebutyrate, acetylated mono, di, and triglycerides, poly(vinylpyrrolidone), vinyl acetate polymers and copolymers, poly(alkylene glycol), styrene butadiene copolymers, poly(orthoesters), alkyd resins, and mixtures of two or more of these. Polymers that are biodegradable are also useful in the present invention. As used herein, a polymer is biodegradable if is not water soluble, but is degraded over a period of several weeks when placed in an application environment. Examples of biodegradable polymers that are useful in the present invention include biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, poly(lactic acid-glycolic acid) copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch esteraliphatic polyester blends, modified corn starch, polycaprolactone, poly(namylmethacrylate), wood rosin, polyanhydrides, polyvinylalcohol, polyhydroxybutyratevalerate, biodegradable aliphatic polyesters, and polyhydroxybutyrate or mixtures thereof. The examples of dispersing agents are alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO block copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide
Examplse of Anti-freezing agent for suspension concentrates include, but not limited to, ethylene glycol, propane diols, glycerin or the urea, glycol (monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol), glycerin, urea, magnesium sulfate heptahydrate, sodium chloride.
Examplse of Anti-freezing agent used for Suspo Emulsion (SE) formulation include, but not limited to, ethylene glycol, propane diols, glycerine or the urea, glycol (monoethylene glycol, diethylene glycol, polypropylene glycol, polyethylene glycol), glycerine, urea, magnesium sulfate heptahydrate, sodium chloride
Water-based formulations often cause foam during mixing operations in production. In order to reduce the tendency to foam, anti-foam agents are often added either during the production stage or before filling into bottles. Generally, there are two types of antifoam agents, namely silicones and non-silicones. Silicones are usually aqueous emulsions of dimethyl poly siloxane while the non-silicone anti-foam agents are water- insoluble oils, such as octanol and nonanol, or silica. In both cases, the function of the anti-foam agent is to displace the surfactant from the air-water interface. Examples of antifoaming agent used for suspension concentrates include, but not limited to, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethyl siloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane.
Examples of antifoaming agent used for WG (Wettable Granule), WDG (Water Dispersible Granule) formulation include, but not limited to, polydimethylsiloxane.
Examples of antifoaming agent used for Suspo Emulsion (SE) formulation include, but not limited to, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethylsiloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane.
A wetting agent is a substance that when added to a liquid increases the spreading or penetration power of the liquid by reducing the interfacial tension between the liquid and the surface on which it is spreading. Wetting agents are used for two main functions in agrochemical formulations: during processing and manufacture to increase the rate of wetting of powders in water to make concentrates for soluble liquids or suspension concentrates; and during mixing of a product with water in a spray tank or other vessel to reduce the wetting time of wettable powders and to improve the penetration of water into water-dispersible granules. Examples of wetting agents used in wettable powder, suspension concentrate formulations include, but not limited to, ethylene oxide/propylene oxide block copolymer, polyarylphenyl ether phosphate, polyalkoxylated butyl ether, ethoxylated fatty alcohol, sodium dioctyl sulfosuccinate, sodium lauryl sulfate and sodium dodecyl benzene sulfonate, alkyl diphenyl sulfonates, sodium isopropyl naphthalene sulfonate, alkyl naphthalene sulfonate, organosilicons surfactants (as a wetting-spreading-penetrating agent) includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.
Examples of wetting agents used in WG (Wettable Granule), WDG (Water Dispersible Granule) formulation include, but not limited to, sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.
Examples of wetting agents used in Suspo Emulsion (SE) formulation include, but not limited to, Ethylene oxide/propylene oxide block copolymer, Polyarylphenyl ether phosphate, Ethoxylated Fatty Alcohol, Sodium dioctyl sulfosuccinate, sodium lauryl sulphate and sodium dodecyl benzene sulfonate, alkyl diphenyl sulfonates, sodium isopropyl naphthalene sulfonate, Alkyl naphthalene sulfonate, Octyl phenol ethoxylate, alkyl phenol ethoxylate.
Examples of wetting-spreading penetrating agent used herein Suspo Emulsion (SE) formulation include, but are not limited to, Organosilicone surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, 10 mole ethylene oxide adduct of octylphenol, may or may not be in modified form, may be liquid or powder form or mixture thereof
Suspension aid in the present description denotes a natural or synthetic, organic or inorganic material with which the active substance is combined in order to facilitate its application to the plant, to the seeds or to the soil. This carrier is hence generally inert, and it must be agriculturally acceptable, in particular to the plant being treated. The carrier may be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, and the like or mixtures thereof) or liquid (water, alcohols, ketones, petroleum fractions, aromatic or paraffinic hydrocarbons, chlorinated hydrocarbons, liquefied gases, and the like or mixtures thereof). The examples of suspending agents used in Suspo Emulsion (SE) formulation include, but not limited to, aluminum magnesium silicate, bentonite clay, silica, silicone dioxide, attapulgite clay.
The examples of suspending agents used in Suspension Concentrate (SC) formulation include, but not limited to, aluminum magnesium silicate, bentonite clay, silica, attapulgite clay.
The examples of carrier used in WG (Wettable Granule), WDG (Water Dispersible Granule) formulation include, but not limited to, china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers
Biocides / Microorganisms cause spoilage of formulated products. Therefore antimicrobial agents are used to eliminate or reduce their effect. Examples of such agents used in suspension concentrate formulations include, but not limited to, 1,2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenyl phenate, 5-chloro-2-methyl-4-isothiazolin-3-one & 2-methyl-4-isothiazolin-3-one.
Examples of preservatives used in used in Suspo Emulsion (SE) formulation include, but not limited, propionic acid and its sodium salt, sorbic acid and its sodium or potassium salt, benzoic acid and its sodium salt, p-hydroxy benzoic acid sodium salt; methyl p-hydroxy benzoate; and biocide such as sodium benzoate, 1,2-benzisothiazoline-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2- methyl-4-isothiazolin-3-one, potassium sorbate, para hydroxy benzoates or mixtures thereof.
Thickeners or gelling agents are used mainly in the formulation of suspension concentrates, emulsions and suspoemulsions to modify the rheology or flow properties of the liquid and to prevent separation and settling of the dispersed particles or droplets. Thickening, gelling, and anti-settling agents generally fall into two categories, namely water-insoluble particulates and water-soluble polymers. It is possible to produce suspension concentrate formulations using clays and silicas. Examples of these types of materials, include, but are limited to, montmorillonite, e.g. bentonite; magnesium aluminum silicate; and attapulgite. Water-soluble polysaccharides have been used as thickening-gelling agents for many years. The types of polysaccharides most commonly used are natural extracts of seeds and seaweeds are synthetic derivatives of cellulose or mixtures thereof. Examples of these types of materials include, but are not limited to, guar gum; locust bean gum; carrageenam; xanthan gum; alginates; methyl cellulose; sodium carboxymethyl cellulose (SCMC); hydroxyethyl cellulose (HEC) or mixtures thereof. Other types of anti-settling agents are based on modified starches, polyacrylates, polyvinyl alcohol and polyethylene oxide or mixtures. Examples of thickeners used in Suspension Concentrate formulation include, but not limited to, xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch.
Examples of thickeners used in Suspo Emulsion (SE) formulation include, but not limited to, Thickening, gelling, and anti-settling agents generally fall into two categories, namely water-insoluble particulates and water-soluble polymers. It is possible to produce suspension concentrate formulations using clays and silicas. Examples of these types of materials, include, but are limited to, montmorillonite, e.g. bentonite; magnesium aluminum silicate; and attapulgite. Water-soluble polysaccharides have been used as thickening-gelling agents for many years. The types of polysaccharides most commonly used are natural extracts of seeds and 15 seaweeds are synthetic derivatives of cellulose or mixtures thereof. Examples of these types of materials include, but are not limited to, guar gum; locust bean gum; carrageenam; xanthan gum; alginates; methyl cellulose; sodium carboxymethyl cellulose (SCMC); hydroxyethyl cellulose (HEC) or mixtures thereof. Other types of anti-settling agents are based on modified starches, polyacrylates, polyvinyl 20 alcohol and polyethylene oxide or mixtures.
The quick coating agent can be a conventionally available sticker, for example polyesters, polyamides, poly- carbonates, polyurea and polyurethanes, acrylate polymers and copolymers, styrene copolymers, butadiene copolymers, polysaccharides such as starch and cellulose derivatives, vinyl alcohol, vinyl acetate and vinyl pyrrolidone polymers and copolymers, polyethers, epoxy, phenolic and melamine resins, polyolefins and define copolymers and mixtures thereof. Examples of preferred polymers are acrylate polymers such as poly(methacrylate), poly(ethyl methacrylate), poly(methyl methacrylate), acrylate copoylmers and styrene-acrylic copolymers as defined herein below, poly(styrene-co maleic anhydride), cellulosic polymers such as ethyl cellulose, cellulose acetate, cellulose acetatebutyrate, acetylated mono, di, and triglycerides, poly(vinyl pyrrolidone), vinyl acetate polymers and copolymers, poly(alkylene glycol), styrene butadiene copolymers, poly(ortho esters), alkyd resins, and mixtures of two or more of these.
Polymers that are biodegradable are also useful in the present invention. As used herein, a polymer is biodegradable if is not water soluble, but is degraded over a period of several weeks when placed in an application environment. Examples of biodegradable polymers that are useful in the present invention include biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, poly(lactic acid-glycolic acid) copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch ester aliphatic polyester blends, modified corn starch, poly capro lactone, poly(namylmethacrylate), wood rosin, poly anhydrides, poly vinyl alcohol, poly hydroxyl butyrate valerate, biodegradable aliphatic polyesters, and poly hydroxyl butyrate or mixtures thereof.
Buffering agent as used herein Suspo Emulsion (SE) formulation include, but not limited to, calcium hydroxyapatite, Potassium Dihydrogen Phosphate, Sodium Hydroxide, carbonated apatite, calcium carbonate, sodium bicarbonate, tricalcium phosphate, calcium phosphates, carbonated calcium phosphates, amine monomers, lactate dehydrogenase and magnesium hydroxide.
The examples of solvent used in Suspo Emulsion (SE) formulation include, but not limited to, includes water, water soluble alcohols and dihydroxy alcohol ethers. Water soluble alcohol or lower alcohol (1-4 carbon atoms) includes-methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol. Macromolecular alcohol includes polyethylene glycol, sorbitol, glucitol etc., dihydroxy alcohol ethers includes dihydroxy alcohol alkyl ether or dihydroxy alcohol aryl ethers. The examples of dihydroxy alcohol alkyl ether include ethylene glycol methyl ether, diethylene glycol methyl ether, propylene glycol methyl ether, di-propylene glycol methyl ether, ethylene glycol ethyl ether, diethylene glycol ethyl ether, propylene glycol ethyl ether, di-propylene glycol ethyl ether, etc. The examples of dihydroxy alcohol aryl ethers include ethylene glycol phenyl ether, 5 diethylene glycol phenyl ether, propylene glycol phenyl ether, di-propylene glycol phenyl ether, and the like. Any of the mentioned solvent can be used either alone or in combinations thereof. Paraffinic hydrocarbons, cyclohexanone, isophorone and ester solvents such as methyloleate, dimethylamide and morpholineamide derivatives of C6-C16 fatty acids, and mono-alkylene carbonates such as ethylene carbonate, propylene carbonate and butylene carbonates, dimethylsulfoxide (DMSO), 2-ethylhexanol and n-butanol, n-alkylpyrrolidones, fatty acid dimethyl esters, fatty acid esters, dibasic esters, aromatic hydrocarbons and/or aliphatic hydrocarbons, one or more dimethylamides, such as C8-dimethylamide, C10-dimethylamide, C12-dimethylamide, ethylene glycol, propylene glycol, polyalkylene glycols, aromatic hydrocarbons, methylpyrrolidinone (NMP); dimethylformamide (DMF); dimethylisosorbide (DMI); isophorone; acetophenone; 1,3-dimethyl-2-imidazolidonone; lactate esters; dimethyl and diethylcarbonates; alcohols including methanol; ethanol; iso-propanol; n-propanol; n-butanol; iso-butanol; and tert-butanol; Methyl L-lactate, 2-Ethylhexyl L-lactate, Ethyl L-lactate, n-Butyl L-lactate, Octyl phenyl ethoxylates.
The examples of emulsifiers used in Suspo Emulsion (SE) formulation include, but not limited to, salts of dodecylbenzene sulphonate, e.g. Ca-salts or amine salts, and sulphonates of other C11-C16 alkylbenzenes, alkylether sulphates, alkylphenoletherphosphates and ester phosphates; non-ionic surfactants such as alkoxylated alcohols and alkylphenols, ethoxylated fatty acids, ethoxylated vegetable oils, e.g. ethoxylated castor oil, fatty acid esters, e.g. of sorbitol, and their ethoxylated derivatives, ethoxylated amines, and condensates of glycerol; and catanionic emulsifiers such as a cationic amine, optionally in combination with an alkylsulphonate or ether sulphonate or ether phosphate, alkoxylated alcohols; alkoxylated alkylphenols; ethoxylated fatty acids; ethoxylated vegetable oils; ethoxylated tristyrylphenol; fatty acid esters of sorbitol and ethoxylated derivatives thereof; ethoxylated amines and condensates of glycerol; sulfonated alkylbenzenes in the range C11-C16 and salts thereof; alkylether sulphates; alkyletherphosphates; alkylphenoletherphosphates; or combinations thereof; salts of phosphate esters of ethoxylated tristyrylphenol; salts of sulphated ethers of ethoxylated tristyrylphenol; or a catanionic system, wherein a cationic amine is present in combination with an alkylsulphonate, an alkylethersulphonate, an ether sulphate, or an ether phosphate such as an alkyletherphosphate, nonylphenol polyethoxy ethanols, castor oil polyglycol ethers, polyadducts of ethylene oxide and polypropylene, tributyl phenoxy polyethoxy ethanol, octyl phenoxy polyethoxy ethanol.
Examples of disintegrating agents used in WG / WDG (Water Dispersible Granule) formulation include, but not limited to, citric acid, succinic acid or the sodium bicarbonate.
Examples of stabilizer used herein Suspo Emulsion (SE) formulation include, but not limited to, butylated hydroxytoluene (BHT) and epoxidized soybean oil (ESBO), Epichlorhydrin.

Lists of combinations

Compound A-An Insecticide from chordotonal organs modulators Compound B-Triazole fungicide Compound C- An Insecticide
Pymetrozine Difenoconazole Acephate
Pymetrozine Difenoconazole Fipronil
Pymetrozine Difenoconazole Bifenthrin
Pymetrozine Difenoconazole Lambda cyhalothrin
Pymetrozine Difenoconazole Fenpropathrin
Pymetrozine Difenoconazole Dinotefuran
Pymetrozine Difenoconazole Flupyrimin
Pymetrozine Difenoconazole Dichloromezotiaz
Pymetrozine Difenoconazole Emamectin benzoate
Pymetrozine Difenoconazole Cartap hydrochloride
Pymetrozine Difenoconazole Thiocyclam
Pymetrozine Difenoconazole Thiosultap
Pymetrozine Difenoconazole Novaluron
Pymetrozine Difenoconazole Teflubenzuron
Pymetrozine Difenoconazole Buprofezin
Pymetrozine Difenoconazole Methoxyfenozide
Pymetrozine Difenoconazole Chromafenozide
Pymetrozine Difenoconazole Tolfenpyrad
Pymetrozine Difenoconazole Chlorantraniliprole
Pymetrozine Difenoconazole Cyantraniliprole
Pymetrozine Difenoconazole Cyclaniliprole
Pymetrozine Difenoconazole Cyhalodiamide
Pymetrozine Difenoconazole Cyproflanilide
Pymetrozine Difenoconazole Flubendiamide
Pymetrozine Difenoconazole Tetraniliprole
Pymetrozine Difenoconazole Tetrachlorantraniliprole
Pymetrozine Difenoconazole Tyclopyrazoflor
Pymetrozine Difenoconazole Broflanilide
Pymetrozine Difenoconazole Fluxametamide
Pymetrozine Difenoconazole Isocycloseram
Pymetrozine Difenoconazole Azadirachtin
Pymetrozine Difenoconazole Benzpyrimoxan
Pymetrozine Difenoconazole Oxazosulfyl
Pymetrozine Tebuconazole Acephate
Pymetrozine Tebuconazole Fipronil
Pymetrozine Tebuconazole Bifenthrin
Pymetrozine Tebuconazole Lambda cyhalothrin
Pymetrozine Tebuconazole Fenpropathrin
Pymetrozine Tebuconazole Dinotefuran
Pymetrozine Tebuconazole Flupyrimin
Pymetrozine Tebuconazole Dichloromezotiaz
Pymetrozine Tebuconazole Emamectin benzoate
Pymetrozine Tebuconazole Cartap hydrochloride
Pymetrozine Tebuconazole Thiocyclam
Pymetrozine Tebuconazole Thiosultap
Pymetrozine Tebuconazole Novaluron
Pymetrozine Tebuconazole Teflubenzuron
Pymetrozine Tebuconazole Buprofezin
Pymetrozine Tebuconazole Methoxyfenozide
Pymetrozine Tebuconazole Chromafenozide
Pymetrozine Tebuconazole Tolfenpyrad
Pymetrozine Tebuconazole Chlorantraniliprole
Pymetrozine Tebuconazole Cyantraniliprole
Pymetrozine Tebuconazole Cyclaniliprole
Pymetrozine Tebuconazole Cyhalodiamide
Pymetrozine Tebuconazole Cyproflanilide
Pymetrozine Tebuconazole Flubendiamide
Pymetrozine Tebuconazole Tetraniliprole
Pymetrozine Tebuconazole Tetrachlorantraniliprole
Pymetrozine Tebuconazole Tyclopyrazoflor
Pymetrozine Tebuconazole Broflanilide
Pymetrozine Tebuconazole Fluxametamide
Pymetrozine Tebuconazole Isocycloseram
Pymetrozine Tebuconazole Azadirachtin
Pymetrozine Tebuconazole Benzpyrimoxan
Pymetrozine Tebuconazole Oxazosulfyl
Pymetrozine Propiconazole Acephate
Pymetrozine Propiconazole Fipronil
Pymetrozine Propiconazole Bifenthrin
Pymetrozine Propiconazole Lambda cyhalothrin
Pymetrozine Propiconazole Fenpropathrin
Pymetrozine Propiconazole Dinotefuran
Pymetrozine Propiconazole Flupyrimin
Pymetrozine Propiconazole Dichloromezotiaz
Pymetrozine Propiconazole Emamectin benzoate
Pymetrozine Propiconazole Cartap hydrochloride
Pymetrozine Propiconazole Thiocyclam
Pymetrozine Propiconazole Thiosultap
Pymetrozine Propiconazole Novaluron
Pymetrozine Propiconazole Teflubenzuron
Pymetrozine Propiconazole Buprofezin
Pymetrozine Propiconazole Methoxyfenozide
Pymetrozine Propiconazole Chromafenozide
Pymetrozine Propiconazole Tolfenpyrad
Pymetrozine Propiconazole Chlorantraniliprole
Pymetrozine Propiconazole Cyantraniliprole
Pymetrozine Propiconazole Cyclaniliprole
Pymetrozine Propiconazole Cyhalodiamide
Pymetrozine Propiconazole Cyproflanilide
Pymetrozine Propiconazole Flubendiamide
Pymetrozine Propiconazole Tetraniliprole
Pymetrozine Propiconazole Tetrachlorantraniliprole
Pymetrozine Propiconazole Tyclopyrazoflor
Pymetrozine Propiconazole Broflanilide
Pymetrozine Propiconazole Fluxametamide
Pymetrozine Propiconazole Isocycloseram
Pymetrozine Propiconazole Azadirachtin
Pymetrozine Propiconazole Benzpyrimoxan
Pymetrozine Propiconazole Oxazosulfyl
Pymetrozine Hexaconazole Acephate
Pymetrozine Hexaconazole Fipronil
Pymetrozine Hexaconazole Bifenthrin
Pymetrozine Hexaconazole Lambda cyhalothrin
Pymetrozine Hexaconazole Fenpropathrin
Pymetrozine Hexaconazole Dinotefuran
Pymetrozine Hexaconazole Flupyrimin
Pymetrozine Hexaconazole Dichloromezotiaz
Pymetrozine Hexaconazole Emamectin benzoate
Pymetrozine Hexaconazole Cartap hydrochloride
Pymetrozine Hexaconazole Thiocyclam
Pymetrozine Hexaconazole Thiosultap
Pymetrozine Hexaconazole Novaluron
Pymetrozine Hexaconazole Teflubenzuron
Pymetrozine Hexaconazole Buprofezin
Pymetrozine Hexaconazole Methoxyfenozide
Pymetrozine Hexaconazole Chromafenozide
Pymetrozine Hexaconazole Tolfenpyrad
Pymetrozine Hexaconazole Chlorantraniliprole
Pymetrozine Hexaconazole Cyantraniliprole
Pymetrozine Hexaconazole Cyclaniliprole
Pymetrozine Hexaconazole Cyhalodiamide
Pymetrozine Hexaconazole Cyproflanilide
Pymetrozine Hexaconazole Flubendiamide
Pymetrozine Hexaconazole Tetraniliprole
Pymetrozine Hexaconazole Tetrachlorantraniliprole
Pymetrozine Hexaconazole Tyclopyrazoflor
Pymetrozine Hexaconazole Broflanilide
Pymetrozine Hexaconazole Fluxametamide
Pymetrozine Hexaconazole Isocycloseram
Pymetrozine Hexaconazole Azadirachtin
Pymetrozine Hexaconazole Benzpyrimoxan
Pymetrozine Hexaconazole Oxazosulfyl
Pymetrozine Tricyclazole Acephate
Pymetrozine Tricyclazole Fipronil
Pymetrozine Tricyclazole Bifenthrin
Pymetrozine Tricyclazole Lambda cyhalothrin
Pymetrozine Tricyclazole Fenpropathrin
Pymetrozine Tricyclazole Dinotefuran
Pymetrozine Tricyclazole Flupyrimin
Pymetrozine Tricyclazole Dichloromezotiaz
Pymetrozine Tricyclazole Emamectin benzoate
Pymetrozine Tricyclazole Cartap hydrochloride
Pymetrozine Tricyclazole Thiocyclam
Pymetrozine Tricyclazole Thiosultap
Pymetrozine Tricyclazole Novaluron
Pymetrozine Tricyclazole Teflubenzuron
Pymetrozine Tricyclazole Buprofezin
Pymetrozine Tricyclazole Methoxyfenozide
Pymetrozine Tricyclazole Chromafenozide
Pymetrozine Tricyclazole Tolfenpyrad
Pymetrozine Tricyclazole Chlorantraniliprole
Pymetrozine Tricyclazole Cyantraniliprole
Pymetrozine Tricyclazole Cyclaniliprole
Pymetrozine Tricyclazole Cyhalodiamide
Pymetrozine Tricyclazole Cyproflanilide
Pymetrozine Tricyclazole Flubendiamide
Pymetrozine Tricyclazole Tetraniliprole
Pymetrozine Tricyclazole Tetrachlorantraniliprole
Pymetrozine Tricyclazole Tyclopyrazoflor
Pymetrozine Tricyclazole Broflanilide
Pymetrozine Tricyclazole Fluxametamide
Pymetrozine Tricyclazole Isocycloseram
Pymetrozine Tricyclazole Azadirachtin
Pymetrozine Tricyclazole Benzpyrimoxan
Pymetrozine Tricyclazole Oxazosulfyl
Pymetrozine Cyproconazole Acephate
Pymetrozine Cyproconazole Fipronil
Pymetrozine Cyproconazole Bifenthrin
Pymetrozine Cyproconazole Lambda cyhalothrin
Pymetrozine Cyproconazole Fenpropathrin
Pymetrozine Cyproconazole Dinotefuran
Pymetrozine Cyproconazole Flupyrimin
Pymetrozine Cyproconazole Dichloromezotiaz
Pymetrozine Cyproconazole Emamectin benzoate
Pymetrozine Cyproconazole Cartap hydrochloride
Pymetrozine Cyproconazole Thiocyclam
Pymetrozine Cyproconazole Thiosultap
Pymetrozine Cyproconazole Novaluron
Pymetrozine Cyproconazole Teflubenzuron
Pymetrozine Cyproconazole Buprofezin
Pymetrozine Cyproconazole Methoxyfenozide
Pymetrozine Cyproconazole Chromafenozide
Pymetrozine Cyproconazole Tolfenpyrad
Pymetrozine Cyproconazole Chlorantraniliprole
Pymetrozine Cyproconazole Cyantraniliprole
Pymetrozine Cyproconazole Cyclaniliprole
Pymetrozine Cyproconazole Cyhalodiamide
Pymetrozine Cyproconazole Cyproflanilide
Pymetrozine Cyproconazole Flubendiamide
Pymetrozine Cyproconazole Tetraniliprole
Pymetrozine Cyproconazole Tetrachlorantraniliprole
Pymetrozine Cyproconazole Tyclopyrazoflor
Pymetrozine Cyproconazole Broflanilide
Pymetrozine Cyproconazole Fluxametamide
Pymetrozine Cyproconazole Isocycloseram
Pymetrozine Cyproconazole Azadirachtin
Pymetrozine Cyproconazole Benzpyrimoxan
Pymetrozine Cyproconazole Oxazosulfyl
Pymetrozine Epoxiconazole Acephate
Pymetrozine Epoxiconazole Fipronil
Pymetrozine Epoxiconazole Bifenthrin
Pymetrozine Epoxiconazole Lambda cyhalothrin
Pymetrozine Epoxiconazole Fenpropathrin
Pymetrozine Epoxiconazole Dinotefuran
Pymetrozine Epoxiconazole Flupyrimin
Pymetrozine Epoxiconazole Dichloromezotiaz
Pymetrozine Epoxiconazole Emamectin benzoate
Pymetrozine Epoxiconazole Cartap hydrochloride
Pymetrozine Epoxiconazole Thiocyclam
Pymetrozine Epoxiconazole Thiosultap
Pymetrozine Epoxiconazole Novaluron
Pymetrozine Epoxiconazole Teflubenzuron
Pymetrozine Epoxiconazole Buprofezin
Pymetrozine Epoxiconazole Methoxyfenozide
Pymetrozine Epoxiconazole Chromafenozide
Pymetrozine Epoxiconazole Tolfenpyrad
Pymetrozine Epoxiconazole Chlorantraniliprole
Pymetrozine Epoxiconazole Cyantraniliprole
Pymetrozine Epoxiconazole Cyclaniliprole
Pymetrozine Epoxiconazole Cyhalodiamide
Pymetrozine Epoxiconazole Cyproflanilide
Pymetrozine Epoxiconazole Flubendiamide
Pymetrozine Epoxiconazole Tetraniliprole
Pymetrozine Epoxiconazole Tetrachlorantraniliprole
Pymetrozine Epoxiconazole Tyclopyrazoflor
Pymetrozine Epoxiconazole Broflanilide
Pymetrozine Epoxiconazole Fluxametamide
Pymetrozine Epoxiconazole Isocycloseram
Pymetrozine Epoxiconazole Azadirachtin
Pymetrozine Epoxiconazole Benzpyrimoxan
Pymetrozine Epoxiconazole Oxazosulfyl
Pymetrozine Flusilazole Acephate
Pymetrozine Flusilazole Fipronil
Pymetrozine Flusilazole Bifenthrin
Pymetrozine Flusilazole Lambda cyhalothrin
Pymetrozine Flusilazole Fenpropathrin
Pymetrozine Flusilazole Dinotefuran
Pymetrozine Flusilazole Flupyrimin
Pymetrozine Flusilazole Dichloromezotiaz
Pymetrozine Flusilazole Emamectin benzoate
Pymetrozine Flusilazole Cartap hydrochloride
Pymetrozine Flusilazole Thiocyclam
Pymetrozine Flusilazole Thiosultap
Pymetrozine Flusilazole Novaluron
Pymetrozine Flusilazole Teflubenzuron
Pymetrozine Flusilazole Buprofezin
Pymetrozine Flusilazole Methoxyfenozide
Pymetrozine Flusilazole Chromafenozide
Pymetrozine Flusilazole Tolfenpyrad
Pymetrozine Flusilazole Chlorantraniliprole
Pymetrozine Flusilazole Cyantraniliprole
Pymetrozine Flusilazole Cyclaniliprole
Pymetrozine Flusilazole Cyhalodiamide
Pymetrozine Flusilazole Cyproflanilide
Pymetrozine Flusilazole Flubendiamide
Pymetrozine Flusilazole Tetraniliprole
Pymetrozine Flusilazole Tetrachlorantraniliprole
Pymetrozine Flusilazole Tyclopyrazoflor
Pymetrozine Flusilazole Broflanilide
Pymetrozine Flusilazole Fluxametamide
Pymetrozine Flusilazole Isocycloseram
Pymetrozine Flusilazole Azadirachtin
Pymetrozine Flusilazole Benzpyrimoxan
Pymetrozine Flusilazole Oxazosulfyl
Pymetrozine Prothioconazole Acephate
Pymetrozine Prothioconazole Fipronil
Pymetrozine Prothioconazole Bifenthrin
Pymetrozine Prothioconazole Lambda cyhalothrin
Pymetrozine Prothioconazole Fenpropathrin
Pymetrozine Prothioconazole Dinotefuran
Pymetrozine Prothioconazole Flupyrimin
Pymetrozine Prothioconazole Dichloromezotiaz
Pymetrozine Prothioconazole Emamectin benzoate
Pymetrozine Prothioconazole Cartap hydrochloride
Pymetrozine Prothioconazole Thiocyclam
Pymetrozine Prothioconazole Thiosultap
Pymetrozine Prothioconazole Novaluron
Pymetrozine Prothioconazole Teflubenzuron
Pymetrozine Prothioconazole Buprofezin
Pymetrozine Prothioconazole Methoxyfenozide
Pymetrozine Prothioconazole Chromafenozide
Pymetrozine Prothioconazole Tolfenpyrad
Pymetrozine Prothioconazole Chlorantraniliprole
Pymetrozine Prothioconazole Cyantraniliprole
Pymetrozine Prothioconazole Cyclaniliprole
Pymetrozine Prothioconazole Cyhalodiamide
Pymetrozine Prothioconazole Cyproflanilide
Pymetrozine Prothioconazole Flubendiamide
Pymetrozine Prothioconazole Tetraniliprole
Pymetrozine Prothioconazole

We claim;
[CLAIM 1]. A synergistic pesticidal composition consisting of chordotonal organ modulators comprising:
a. an insecticide from the class of chordotonal organs modulators selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon or mixture thereof;
b. a fungicide selected from the class of triazole selected from cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole or tricyclazole or mixture thereof;
c. one more insecticide selected from the class of carbamates, organophosphates, phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, mectins, juvenile hormone mimics, mite growth inhibitors, microbial disruptors of insect midgut membrane, inhibitors of mitochondrial ATP synthase, uncouplers of oxidative phosphorylation, nereis toxin, chitin biosynthesis inhibitors, inhibitors of the chitin biosynthesis type 1, moulting disruptors, ecdyson receptor agonists, octopamin receptor agonists, METI (mitochondrial electron transport inhibitors, voltage-dependent sodium channel blockers, tetronic and tetramic acid derivatives, diamides, metadiamides, isoxazolines, from baculoviruses or from the compounds of unknown or uncertain mode of action or from the mixture thereof; and
d. formulation excipients.

[CLAIM 2]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein a fungicide from the class of triazoles is selected from cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, frutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simconazole, tebuconazole, tetraconazole, tiradimefon, tiradimenol, triticonazole or tricyclazole.

[CLAIM 3]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of carbamates is selected from carbaryl, carbofuran, carbosulfan, methomyl, oxamyl, pirimicarb, thiodicarb.

[CLAIM 4]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of organophosphates is selected from acephate, cadusafos, chlorpyrifos, chlorpyrifos-methyl, demeton-S-methyl, dimethoate, ethion, fenamiphos, fenitrothion, fenthion, fosthiazate, methamidophos, monocrotophos, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosphamidon, profenofos, quinalphos, and triazophos.

[CLAIM 5]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of Phenylpyrazole is selected from ethiprole, fipronil, flufiprole, nicofluprole, pyrafluprole, or pyriprole.

[CLAIM 6]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of pyrethroids is selected from bifenthrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, fenpropathrin, fenvalerate, tau-fluvalinate, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin.

[CLAIM 7]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of nicotinic insecticides such as Neonicotinoids is selected from acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam, flupyrimin, cycloxaprid, paichongding, guadipyr, cycloxylidin; Sulfoximines like sulfoxaflor; Butenolides like flupyradifurone; Mesoionics like triflumezopyrim, dichloromezotiaz.

[CLAIM 8]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of spinosyns is selected from spinosad and spinetoram.

[CLAIM 9]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of mectins is selected from abamectin, emamectin benzoate, ivermectin, lepimectin; Milbemycins like milbemectin.

[CLAIM 10]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of juvenile hormone mimics is selected from hydroprene, kinoprene, methoprene, fenoxycarb, pyriproxyfen.

[CLAIM 11]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of spinosyns is selected from spinosad and spinetoram.

[CLAIM 12]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of mectins is selected from abamectin, emamectin benzoate, ivermectin, lepimectin; Milbemycins like milbemectin.

[CLAIM 13]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of juvenile hormone mimics is selected from hydroprene, kinoprene, methoprene, fenoxycarb, pyriproxyfen.

[CLAIM 14]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of mite growth inhibitors is selected from clofentezine, hexythiazox, diflovidazin or etoxazole.

[CLAIM 15]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of microbial disruptors of insect midgut membrane is selected from Bacillus thuringiensis and insecticidal proteins and their by-products.

[CLAIM 16]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of inhibitors of mitochondrial ATP synthase is selected from diafenthiuron, azocyclotin, cyhexatin, fenbutatin oxide, propargite, or tetradifon.

[CLAIM 17]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of uncouplers of oxidative phosphorylation is selected from chlorfenapyr, DNOC, or sulfluramid.

[CLAIM 18]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, an Insecticide from the class of nereis toxin is selected from bensultap, monosultap, cartap hydrochloride, thiocyclam, thiocyclam hydrogen oxalate, thiocyclam hydrochloride, thiosultap sodium.

[CLAIM 19]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of chitin biosynthesis inhibitors is selected from Benzoylureas-bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, triflumuron.

[CLAIM 20]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of inhibitors of the chitin biosynthesis type-1 is buprofezin.

[CLAIM 21]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of moulting disruptors is cyromazine.

[CLAIM 22]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of ecdyson receptor agonists is selected from diacylhydrazines like methoxyfenozide, tebufenozide, halofenozide, fufenozide or chromafenozide.

[CLAIM 23]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of octopamin receptor agonists is amitraz.

[CLAIM 24]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of METI (mitochondrial electron transport inhibitors) is selected from fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad, flufenerim, rotenone, cyenopyrafen, cyflumetofen, pyflubumidemm, hydramethylnon, acequinocyl, flometoquin, fluacrypyrim, pyriminostrobin or bifenazate.

[CLAIM 25]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an insecticide from the class of voltage-dependent sodium channel blockers is selected from oxadiazines like indoxacarb, semicarbazones like metaflumizone.

[CLAIM 26]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of inhibitors of the lipid synthesis, inhibitors of acetyl CoA carboxylase (Tetronic and tetramic acid derivatives) is selected from spirodiclofen, spiromesifen, spirotetramat or spiropidion.

[CLAIM 27]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of diamide is selected from chlorantraniliprole, cyantraniliprole, cyclaniliprole, cyhalodiamide, cyproflanilide, flubendiamide, tetraniliprole, tetrachlorantraniliprole, tyclopyrazoflor.

[CLAIM 28]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of metadiamide is broflanilide.

[CLAIM 29]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of Isoxazolines is selected from fluxametamide, isocycloseram.

[CLAIM 30]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of Baculoviruses is selected from Granuloviruses and Nucleopolyhedrosis viruses.

[CLAIM 31]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein an Insecticide from the class of compounds of unknown or uncertain mode of action is selected from azadirechtin, benzpyrimoxan (insect growth regulators), pyridalyl, oxazosulfyl, dimpropyridaz (pyrazole 15 carboxamide insecticide), fluhexafon, acaricidal compounds-cyetpyrafen, flupentiofenox, acynonapyr; nematicidal compounds-cyclobutrifluram, fluazaindolizine, or tioxazafen.

[CLAIM 32]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1, wherein the formulation for the said composition is selected from Capsule suspension (CS), Dispersible concentrate (DC), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsion, water in oil (EO), Emulsion for seed treatment (ES), Emulsion, oil in water (EW), Flowable suspension/concentrate for seed treatment (FS), Granule/ soil applied (GR), Controlled (Slow or Fast) release granules (CR), Solution for seed treatment (LS), Micro-emulsion (ME), Oil dispersion (OD), Oil miscible flowable concentrate (oil miscible suspension (OF), Oil miscible liquid (OL), Suspension concentrate (= flowable concentrate) (SC), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Water soluble powder (SP), Water dispersible granule (WG or WDG), Wettable powder (WP), Water dispersible powder for slurry treatment (WS), A mixed formulation of CS and SC (ZC), A mixed formulation of CS and SE (ZE), A mixed formulation of CS and EW (ZW).

[CLAIM 33]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1–claim 32, wherein the preferred compositions of active ingredients comprises:
i Pymetrozine 24%+Hexaconazole 10%+Flupyrimin 15% WG
ii Pymetrozine 24%+Hexaconazole 10%+Triflumezopyrim 4% WG
iii Pymetrozine 24%+Hexaconazole 10%+Benzpyrimoxan 10% WG
iv Flonicamid 6%+Difenoconazole 10%+Spiropidion 10% SC
v Pyrifluquinazon 4%+Tebuconazole 10%+Diafenthiuron 20% SC
vi Pyrifluquinazon 4%+Tebuconazole 10%+Pyriproxyfen 5% SE

[CLAIM 34]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1–claim 32, wherein the preferred compositions of active ingredients for the WG (Water dispersible granule/Wettable Granule) formulation comprises:
i. Pymetrozine 24%+Hexaconazole 10%+Flupyrimin 15%
ii. Pymetrozine 25%+Prothioconazole 20%+Chlorantraniliprole 5%

[CLAIM 35]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 33, wherein the WG (Water dispersible granule/Wettable Granule) formulation comprises:
i. an insecticide from the class of chordotonal organs modulators selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon or mixture thereof present in an amount of 0.1 to 30% by weight of the composition;
ii. a fungicide from the class of triazoles present in an amount of 0.1 to 40% by weight of the composition;
iii. one more insecticide selected from the class of one more insecticide selected from the class of carbamates, organophosphates, phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, 5 mectins, juvenile hormone mimics, mite growth inhibitors, microbial disruptors of insect midgut membrane, inhibitors of mitochondrial ATP synthase, uncouplers of oxidative phosphorylation, nereis toxin, chitin biosynthesis inhibitors, inhibitors of the chitin biosynthesis type 1, moulting disruptors, ecdyson receptor agonists, octopamin receptor agonists, METI (mitochondrial electron transport inhibitors, voltage-10 dependent sodium channel blockers, tetronic and tetramic acid derivatives, diamides, metadiamides, isoxazolines, from baculoviruses or from the compounds of unknown or uncertain mode of action or from the mixture thereof present in an amount of 0.1 to 30% by weight of the composition;
iv. wetting agent in an amount of 4 to 10 % by weight;
v. dispersing agent 1 in an amount of 2 to 10 % by weight;
vi. dispersing agent 2 in an amount of 2 to 5 % by weight;
vii. disintegrating agent in an amount of 4 to 10 % by weight;
viii. antifoaming agent in an amount of 0.1 to 1 % by weight; and
ix. carrier in an amount of 25 to 30 % by weight.

[CLAIM 36]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 33, wherein wetting agent is selected from sodium N-methyl-N-oleoyl taurate, alkylated naphthalene sulfonate, sodium salt, mixture of isomers of dibutyl naphthalene sulphonic acid sodium salt, sodium di-isopropyl naphthalene sulphonate, sodium Lauryl sulfate, dioctyl sulfate, alkyl naphthalene sulfonates, phosphate esters, sulphosuccinates and non-ionic such as tridecyl alcohol ethoxylate, alkyl or alkaryl sulfonates such as alkylbenzene sulfonates, alpha olefin sulfonate and alkyl naphthalene sulfonates, ethoxylated or non-ethoxylated alkyl or alkaryl carboxylates, alkyl or alkaryl phosphate esters, alkyl polysaccharide, di or mono alkyl sulfosuccinate derivatives, alpha olefin sulfonates, alkyl naphthalene sulfonates, dialkyl sulphosuccinates, butyl, dibutyl, isopropyl and di-isopropyl naphthalene sulfonate salts, C12 alkyl benzene sulfonate or C10-C16 alkyl benzene sulfonate, organosilicons surfactants includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.

[CLAIM 37]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 33, wherein dispersing agents are selected from naphthalene sulfonic acid, sodium salt condensates with formaldehyde, polyalcoxylated alkylphenol, naphthalene sulfonic acid formaldehyde condensate, methyl naphthalene-formaldehyde-condensate sodium salt, naphthalene condensates, lignosulfonates, polyacrylates and phosphate esters, calcium lignosulfonate, lignin sulfonate sodium salt.

[CLAIM 38]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 33, wherein disintegrating agent is selected from citric acid, succinic acid and sodium bicarbonate.

[CLAIM 39]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 33, wherein antifoaming agent is polydimethylsiloxane

[CLAIM 40]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 33, wherein carrier is selected from china clay, silica, lactose anhydrous, ammonium sulfate, sodium sulfate anhydrous, corn starch, urea, EDTA, urea formaldehyde resin, diatomaceous earth, kaolin, bentonite, kieselguhr, fuller's earth, attapulgite clay, bole, loess, talc, chalk, dolomite, limestone, lime, calcium carbonate, powdered magnesia, magnesium oxide, magnesium sulphate, sodium chloride, gypsum, calcium sulphate, pyrophyllite, silicates and silica gels; fertilizers such as, for example, ammonium sulphate, ammonium phosphate, ammonium nitrate and urea; natural products of vegetable origin such as, for example, grain meals and flours, bark meals, wood meals, nutshell meals and cellulosic powders; and synthetic polymeric materials such as, for example, ground or powdered plastics and resins, bentonites, zeolites, titanium dioxide, iron oxides and hydroxides, aluminium oxides and hydroxides, or organic materials such as bagasse, charcoal, or synthetic organic polymers.

[CLAIM 41]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1–claim 32, wherein the preferred compositions of active ingredients for the SC (Suspension Concentrate) formulation comprises:

i Flonicamid 6%+Difenoconazole 10%+Spiropidion 10%

[CLAIM 42]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein the SC (Suspension Concentrate) formulation comprises:

i. an insecticide from the class of chordotonal organs modulators selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon or mixture thereof present in an amount of 0.1 to 30% by weight of the composition;
ii. a fungicide from the class of triazoles present in an amount of 0.1 to 40% by weight of the composition;
iii. one more insecticide selected from the class of one more insecticide selected from the class of carbamates, organophosphates, phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, 5 mectins, juvenile hormone mimics, mite growth inhibitors, microbial disruptors of insect midgut membrane, inhibitors of mitochondrial ATP synthase, uncouplers of oxidative phosphorylation, nereis toxin, chitin biosynthesis inhibitors, inhibitors of the chitin biosynthesis type 1, moulting disruptors, ecdyson receptor agonists, octopamin receptor agonists, METI (mitochondrial electron transport inhibitors, voltage-10 dependent sodium channel blockers, tetronic and tetramic acid derivatives, diamides, metadiamides, isoxazolines, from baculoviruses or from the compounds of unknown or uncertain mode of action or from the mixture thereof present in an amount of 0.1 to 30% by weight of the composition;
iv. wetting-spreading-penetrating agent in an amount of 4 to 10 % by weight;
v. dispersing agent 1 in an amount of 1 to 5 % by weight;
vi. dispersing agent 2 in an amount of 1 to 5 % by weight;
vii. suspending agent in an amount of 0.5 to 3 % by weight;
viii. antifoaming agent in an amount of 0.1 to 1 % by weight;
ix. preservative in an amount of 0.1 to 0.5 % by weight;
x. antifreezing agent in an amount of 2 to 6% by weight;
xi. thickner in an amount of 0.1 to 1.0% by weight; and
xii. diluent water in an amount of 40 to 70% by weight.

[CLAIM 43]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein wetting-spreading-penetrating agent is selected from ethylene oxide/propylene oxide block copolymer, polyarylphenyl ether phosphate, polyalkoxylated butyl ether, ethoxylated fatty alcohol, sodium dioctyl sulfosuccinate, sodium lauryl sulfate and sodium dodecyl benzene sulfonate, alkyl diphenyl sulfonates, sodium isopropyl naphthalene sulfonate, alkyl naphthalene sulfonate, organosilicons surfactants (as a wetting-spreading-penetrating agent) includes trisiloxane ethoxylate, polydimethylsiloxane, polyoxyethylene methyl polysiloxane, polyoxyalkylene methyl polysiloxane, polyether polymethyl siloxane copolymer, heptamethyl trisiloxane, Polyalkyleneoxide modified heptamethyl trisiloxane, polyether modified polysiloxane, may or may not be in modified form, may be liquid or powder form or mixture thereof.

[CLAIM 44]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein dispersing agent is selected from alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium polycarboxylate, EO/PO based copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propylene oxide-ethylene oxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycol ether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycol ether-phosphate, oleyl-polyglycol ether with ethylene oxide, tallow fatty amine polyethylene oxide, nonylphenol polyglycol ether with 9-10 moles ethylene oxide.

[CLAIM 45]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein suspending agent is selected from aluminum magnesium silicate, bentonite clay, silica, attapulgite clay.

[CLAIM 46]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein antifoaming agent is selected from silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethyl siloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane.
[CLAIM 47]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein preservative is selected from 1,2-benzisothiazolin-3(2H)-one, sodium salt, sodium benzoate, 2-bromo-2-nitropropane-1,3-diol, formaldehyde, sodium o-phenyl phenate, 5-chloro-2-methyl-4-isothiazolin-3-one & 2-methyl-4-isothiazolin-3-one.

[CLAIM 48]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein anti-freezing agent is selected from ethylene glycol, propane diols, glycerin or the urea, glycol (monoethylene glycol, diethylene glycol, polypropylene glycol, and polyethylene glycol), glycerin, urea, magnesium sulfate heptahydrate, sodium chloride.

[CLAIM 49]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 40, wherein thickner is selected from xanthan gum, PVK, carboxymethyl celluloses, polyvinyl alcohols, gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch.

[CLAIM 50]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 1–claim 32, wherein the preferred compositions of active ingredients for the SE (Suspo Emulsion) formulation comprises:
i Pyrifluquinazon 4%+Tebuconazole 10%+Pyriproxyfen 5%

[CLAIM 51]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein the SE (Suspo Emulsion) formulation comprises:
i. an insecticide from the class of chordotonal organs modulators selected from afidopyropen, flonicamid, pymetrozine, pyrifluquinazon or mixture thereof present in an amount of 0.1 to 30% by weight of the composition;
ii. a fungicide from the class of triazoles present in an amount of 0.1 to 40% by weight of the composition;
iii. one more insecticide selected from the class of one more insecticide selected from the class of carbamates, organophosphates, phenylpyrazole, pyrethroids, nicotinic insecticides, spinosyns, 5 mectins, juvenile hormone mimics, mite growth inhibitors, microbial disruptors of insect midgut membrane, inhibitors of mitochondrial ATP synthase, uncouplers of oxidative phosphorylation, nereis toxin, chitin biosynthesis inhibitors, inhibitors of the chitin biosynthesis type 1, moulting disruptors, ecdyson receptor agonists, octopamin receptor agonists, METI (mitochondrial electron transport inhibitors, voltage-10 dependent sodium channel blockers, tetronic and tetramic acid derivatives, diamides, metadiamides, isoxazolines, from baculoviruses or from the compounds of unknown or uncertain mode of action or from the mixture thereof present in an amount of 0.1 to 30% by weight of the composition;
iv. wetting-spreading-penetrating agent in an amount of 2 to 10 % by weight;
v. solvent in an amount of 5 to 10% by weight;
vi. dispersing agent 1 in an amount of 3 to 8 % by weight;
vii. dispersing agent 2 in an amount of 1 to 5 % by weight;
viii. suspending agent in an amount of 0.5 to 3 % by weight;
ix. antifoaming agent in an amount of 0.1 to 1 % by weight;
x. preservative in an amount of 0.1 to 0.5 % by weight;
xi. antifreezing agent in an amount of 2 to 6% by weight;
xii. thickner in an amount of 0.1 to 1.0% by weight; and
xiii. diluent water in an amount of 40 to 70% by weight.

[CLAIM 52]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein carrier as a solvent is selected from water, water soluble alcohols and dihydroxy alcohol ethers. Water soluble alcohol or lower alcohol (1-4 carbon atoms) includes-methanol, ethanol, n-propanol, isopropanol, n-butanol, tert-butanol. Macromolecular alcohol includes polyethylene glycol, sorbitol, glucitol etc., dihydroxy alcohol ethers includes dihydroxy alcohol alkyl ether or dihydroxy alcohol aryl ethers. The examples of dihydroxy alcohol alkyl ether include ethylene glycol methyl ether, diethylene glycol methyl ether, propylene glycol methyl ether, di-propylene glycol methyl ether, ethylene glycol ethyl ether, diethylene glycol ethyl ether, propylene glycol ethyl ether, di-propylene glycol ethyl ether, etc. The examples of dihydroxy alcohol aryl ethers include ethylene glycol phenyl ether, 5 diethylene glycol phenyl ether, propylene glycol phenyl ether, di-propylene glycol phenyl ether, and the like. Any of the mentioned solvent can be used either alone or in combinations thereof; Paraffinic hydrocarbons, cyclohexanone, isophorone and ester solvents such as methyloleate, dimethylamide and morpholineamide derivatives of C6-C16 fatty acids, and mono-alkylene carbonates such as ethylene carbonate, propylene carbonate and butylene carbonates, dimethylsulfoxide (DMSO), 2-ethylhexanol and n-butanol, n-alkylpyrrolidones, fatty acid dimethyl esters, fatty acid esters, dibasic esters, aromatic hydrocarbons and/or aliphatic hydrocarbons, one or more dimethylamides, such as C8-dimethylamide, C10-dimethylamide, C12-dimethylamide, ethylene glycol, propylene glycol, polyalkylene glycols, aromatic hydrocarbons, methylpyrrolidinone (NMP); dimethylformamide (DMF); dimethylisosorbide (DMI); isophorone; acetophenone; 1,3-dimethyl-2-imidazolidonone; lactate esters; dimethyl and diethylcarbonates; alcohols including methanol; ethanol; iso-propanol; n-propanol; n-butanol; iso-butanol; and tert-butanol; Methyl L-lactate, 2-Ethylhexyl L-lactate, Ethyl L-lactate, n-Butyl L-lactate, Octyl phenyl ethoxylates.

[CLAIM 53]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein dispersing agent is selected from polyesters, polyamides, poly- carbonates, polyurea and polyurethanes, acrylic polymers and copolymers, styrene copolymers, butadiene copolymers, polysaccharides such as starch and cellulose derivatives, vinylalcohol, vinylacetate and vinylpyrrolidone polymers and copolymers, polyethers, epoxy, phenolic and melamine resins, polyolefins and define copolymers and mixtures thereof. Examples of preferred polymers are acrylate polymers such as poly(methacrylate), poly(ethyl methacrylate), poly(methylmethacrylate), acrylate copoylmers and styrene-acrylic copolymers as defined herein below, poly(styrene-co maleic anhydride), cellulosic polymers such as ethyl cellulose, cellulose acetate, cellulose acetatebutyrate, acetylated mono, di, and triglycerides, poly(vinylpyrrolidone), vinyl acetate polymers and copolymers, poly(alkylene glycol), styrene butadiene copolymers, poly(orthoesters), alkyd resins, and mixtures of two or more of these. Polymers that are biodegradable are also useful in the present invention. As used herein, a polymer is biodegradable if is not water soluble, but is degraded over a period of several weeks when placed in an application environment. Examples of biodegradable polymers that are useful in the present invention include biodegradable polyesters, starch, polylactic acid starch blends, polylactic acid, poly(lactic acid-glycolic acid) copolymers, polydioxanone, cellulose esters, ethyl cellulose, cellulose acetate butyrate, starch esters, starch esteraliphatic polyester blends, modified corn starch, polycaprolactone, poly(namylmethacrylate), wood rosin, polyanhydrides, polyvinylalcohol, polyhydroxybutyratevalerate, biodegradable aliphatic polyesters, and polyhydroxybutyrate or mixtures thereof. The examples of dispersing agents are alkylated naphthalene sulfonate, sodium salt, sodium salt of naphthalene sulfonate condensate, sodium ligno sulfonate, sodium ploycarboxylate, EO/PO block copolymer, phenol sulfonate, sodium methyl oleoyl taurate, styrene acrylic acid copolymer, propyleneoxide-ethyleneoxide-copolymer, polyethylene glycol 2,4,6-tristyrylphenyl ether, tristyrylphenol-polyglycolether-phosphate, tristyrylphenole with 16 moles EO, tristyrylphenol-polyglycolether-phosphate, oleyl-polyglycolether with ethylene oxide, tallow fattyamine polyethylene oxide, nonylphenol polyglycolether with 9-10 moles ethylene oxide.

[CLAIM 54]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein suspending agent is selected from aluminum magnesium silicate, bentonite clay, silica, silicone dioxide, and attapulgite clay.

[CLAIM 55]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein antifoaming agent is selected from silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, silicone antifoam emulsion, dimethylsiloxane, polydimethyl siloxane, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane.

[CLAIM 56]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein preservative is selected from propionic acid and its sodium salt, sorbic acid and its sodium or potassium salt, benzoic acid and its sodium salt, p-hydroxy benzoic acid sodium salt; methyl p-hydroxy benzoate; and biocide such as sodium benzoate, 1,2-benzisothiazoline-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2- methyl-4-isothiazolin-3-one, potassium sorbate, para hydroxy benzoates or mixtures thereof.

[CLAIM 57]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein anti-freezing agent is selected from ethylene glycol, propane diols, glycerine or the urea, glycol (monoethylene glycol, diethylene glycol, polypropylene glycol, and polyethylene glycol), glycerine, urea, magnesium sulfate heptahydrate, sodium chloride.

[CLAIM 58]. The synergistic pesticidal composition consisting of chordotonal organ modulators as claimed in claim 49, wherein thickner is selected from montmorillonite, bentonite; magnesium aluminum silicate; and attapulgite, guar gum; locust bean gum; carrageenam; xanthan gum; alginates; methyl cellulose; sodium carboxymethyl cellulose (SCMC); hydroxyethyl cellulose (HEC) or mixtures thereof. Other types of anti-settling agents are based on modified starches, polyacrylates, polyvinyl 20 alcohol and polyethylene oxide or mixtures.

Dated this 19th day of April 2021