DESC:FORM 2
THE PATENTS ACT, 1970
(39 OF 1970)
&
The Patents Rules, 2003
COMPLETE SPECIFICATION
(See section 10; rule 13)

1. TITLE OF THE INVENTION – SYNERGISTIC PESTICIDE COMPOSIITON OF FLONICAMID AND BIFENTHRIN
2. Applicant(s)
a) NAME: MEGHMANI ORGANICS LIMITED
b) NATIONALITY: INDIAN
c) ADDRESS: MEGHMANI HOUSE, BEHIND SAFAL PROFITAIRE, CORPORATE ROAD, PRAHLADNAGAR, AHMEDABAD, GUJARAT, INDIA-380015

3. PREAMBLE TO THE DESCRIPTION
COMPLETE SPECIFICATION
The following specification describes the invention and the manner in which it is to be performed

SYNERGISTIC PESTICIDE COMPOSITION OF FLONICAMID AND BIFENTHRIN

FIELD OF THE INVENTION:
The present invention relates to a synergistic pesticide composition comprising Flonicamid and Bifenthrin. The present invention particularly relates to a synergistic pesticide composition comprising Flonicamid and Bifenthrin and at least one inactive ingredient, wherein the said composition is Suspo-Emulsion (SE) formulation.

BACKGROUND OF THE INVENTION:

Pesticides are the chemicals which are applied on plants to kill or eliminate fungus, bacteria, insects, snails, slugs, or weeds. Pesticides are broadly used in agriculture to facilitate a massive increase in yield of crops and productivity.

Flonicamid [IKI220; N-cyanomethyl-4-(trifluoromethyl) nicotinamide], a pyridine carboxamide compound, is a novel systemic insecticide with selective activity against hemipterous pests, such as aphids and whiteflies, and thysanopterous pests like thrips. It disrupts insect chordotonal organs that can affect hearing, balance, movement to cause cessation of feeding, but the specific target site of the chemical is unknown. Flonicamid is very active against aphids, regardless of differences in species, stages and morphs. Flonicamid has no negative impact on pollinating insects or natural enemies, and thus, Flonicamid provide a new option for integrated pest management programs. Flonicamid also has a good toxicological, environmental and ecotoxicological properties.

Flonicamid is having molecular formula C9H6F3N3O and molecular weight is 229.16 g/mol and having water solubility of 5.2 g/L at 20oC. Flonicamid is stable at pH 4 and pH 5. The amide TFNG-AM is formed from this reaction (under alkaline conditions) and can then be hydrolyzed to TFNG (N-(4- trifluoromethylnicotinoyl) glycine)

Flonicamid was first disclosed in EP0580374B1 and chemically represented as below structure:

Flonicamid is the only insecticide from IRAC (Insecticide Resistance Action Committee) Group 29 class. Flonicamid rapidly inhibits the feeding behavior of aphids, and has better action through ingestion than by contact which is unique compared to existing insecticides.

Flonicamid is useful to provide protection in crops like Soybean, Fruit trees, Cereals, Potatoes, Cotton, Vegetables, Ornamentals, etc.

Flonicamid is commercially marketed as a soluble or wettable granule containing 50% Flonicamid, which is to be mixed with water before spraying.

Bifenthrin is a broad spectrum pyrethroid insecticide used in a wide range of crops to control sucking and biting foliar pests like fire ants, blue grass weevil, armyworms, cutworms, centipedes, crickets, earwigs, millipedes, sowbugs, mole crickets, ticks, fleas, grasshoppers. Bifenthrin was first registered for use by the United States Environmental Protection Agency (U.S. EPA) in 1985.

The IUPAC name of Bifenthrin is 2-methylbiphenyl-3-ylmethyl (Z)-(1RS, 3RS)-3-(2-chloro-3, 3, 3- trifluoroprop-1-enyl) -2, 2-dimethylcyclopropanecarboxylate and the molecular formula is C23H22ClF3O2. The relative Molecular mass of Bifenthrin is 422.87 g/ mol.

Bifenthrin is a Type I pyrethroid which is effective by contact or ingestion. It affects the central and peripheral nervous system by interfering with sodium channel gating and delays the closure of the sodium channel. Bifenthrin tend to hold the channel open for shorter times compared to type II pyrethroids.

Bifenthrin is chiral molecule and is a mixture of the Z-isomer (~99.7%) and the E-isomer (~0.3%). Bifenthrin is chemically represented as below structure:

Bifenthrin is having water solubility of 0.001 mg/ L at 20 °C. Bifenthrin is the insecticide from IRAC (Insecticide Resistance Action Committee) Group 3(A) class.

Bifenthrin is effective against a broad range of foliar pests, including Coleoptera, Diptera, Heteroptera, Homoptera, Lepidoptera and Orthoptera and some species of Acarina.

Bifenthrin is useful to provide protection in crops like cereals, citrus, cotton, grapes, ornamentals and vegetables. Bifenthrin is usually formulated as emulsifiable concentrate, granular, suspension concentrate, ultra-low volume liquid, wettable powder formulation.

In India or anywhere in the world, in agricultural production, using synthetic or chemical agent is the most effective means in order to control pests. However, the main disadvantage of such insecticide or pesticide is that on long run, the insects or pets develop resistance to that insecticide or pesticide and as a result to get effective result, higher concentration of the insecticide or pesticide is to be used. Here again using higher dose of insecticide or pesticide may result in some detrimental effect to soil as well as environment. Therefore in general practice, usually combination of pesticide with another pesticide or another herbicide or fungicide is used in different concentration as per requirement.

However, when combinations of one or more pesticide are used, the main challenge is to develop a formulation or composition which is stable, easy to use and also effective.

There are few formulations of Flonicamid and Bifenthrin either reported individually as well as in combination with other pesticides.

IN 202017024614 describes pesticide composition comprising Flonicamid and D-limonene as active ingredients, in a mixing weight ratio of Flonicamid to D-limonene of from 1:150 to 1:1. This prior art does not comprise Bifenthrin in the combination of Flonicamid.

IN 202031004927 relates to an insecticidal formulation comprising 20% solution of imidacloprid and 5% solution of bifenthrin in a ratio of 5:2 w/w in aqueous solution. This prior art does not comprise Flonicamid in the combination of Bifenthrin.

IN 201617006458 discloses a water-based pesticide suspension comprising (a) Flonicamid, (b) buprofezin, (c) a polycarboxylate, (d) at least one sulfonate type surfactant selected from the group consisting of an alkyl sulfosuccinate, a lignosulfonate, a C8-18 alkylbenzene sulfonate and a C8-18 alkyl diphenyl ether disulfonate, (e) a sodium alkyl naphthalene sulfonate condensed with formaldehyde, and water, wherein, in the suspension, the content of the active ingredients consisting of the component (a) Flonicamid and the component (b) buprofezin is from 5 to 60 wt%, the content of the component (c) polycarboxylate is from 0.1 to 10 wt%, the content of the component (d) the sulfonate type surfactant is from 0.1 to 20 wt% and the content of the sodium alkyl naphthalene sulfonate condensed with formaldehyde as the component (e) is from 0.1 to 10 wt%, and wherein the weight ratio of the active ingredients to the polycarboxylate is from 1:0.005 to 1:2, the weight ratio of the active ingredients to the sulfonate type surfactant as the component (d) is from 1:0.005 to 1:4, the weight ratio of the active ingredients to the sodium alkyl naphthalene sulfonate condensed with formaldehyde is from 1:0.005 to 1:2. This prior art does not comprise Bifenthrin in the combination with Flonicamid.

CN110637827 relates to a hygienic insecticidal composition containing acetamiprid and pyrethroid, the hygienic insecticidal composition comprises the following effective components: 1%-15% of the acetamiprid, 1%-15% of the pyrethroid and the balance of an auxiliary agent. The dosage forms comprise missible oil, emulsion in water, microemulsion and soluble liquid, wherein the pyrethroid is tetramethylfluthrin, dimefluthrin, metofluthrin, dextral trans-permethrin chlorpromazine acetylene, transfluthrin, phenothrin, teflumethrin, dextral teflumethrin, bioallethrin, chlorempenthrin, dextral allethrin and rich dextral trans-allethrin. This prior art nowhere discloses Suspo-Emulsion formulation for the combination of Flonicamid and Bifenthrin.

However, there is no formulation or composition available where Flonicamid and Bifenthrin are combined in a Suspo-Emulsion (SE) formulation which is stable and yet effective.

Inventors of present invention have disclosed a pesticide composition of Flonicamid and Bifenthrin in the form of Suspo-Emulsion (SE) formulation which is stable, effective and overcome all the problems mentioned in prior art as described herein.
OBJECT OF THE INVENTION

The main objective of the present invention is to provide a synergistic pesticide composition of Flonicamid and Bifenthrin which is stable.

The main objective of the present invention is to provide a synergistic pesticide composition of Flonicamid and Bifenthrin which reduces the harmful effects to environment.

The main objective of the present invention is to provide a synergistic pesticide composition of Flonicamid and Bifenthrin which is effective against crop pests.

The main objective of the present invention is to provide a synergistic pesticide composition of Flonicamid and Bifenthrin which is effective and in use at the field.

SUMMARY OF THE INVENTION

The main aspect of the invention is to provide synergistic pesticide composition of Flonicamid and Bifenthrin.

Another aspect of the present invention is to provide pesticide suspension concentrate formulation of Flonicamid and Bifenthrin with one or more inactive ingredients.

Yet another aspect of the present invention is to provide to a synergistic pesticide composition comprising Flonicamid and Bifenthrin and at least one inactive ingredient, wherein the said composition is Suspo-Emulsion (SE) formulation.

DESCRIPTION OF THE INVENTION

The present invention is all about providing a pesticide composition of Flonicamid and Bifenthrin.

The detailed description set forth below is intended as a description of exemplary embodiments and is not intended to represent the only forms in which the exemplary embodiments may be constructed and/or utilized. The description sets forth the functions and the sequence of steps for constructing and/or operating the exemplary embodiments. However, it is to be understood that the same or equivalent functions and sequences which may be accomplished by different exemplary methods are also intended to be encompassed within the spirit and scope of the invention.

As defined herein, all scientific and technical terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention belongs. Although any process and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention, the preferred methods and materials are now described.

As stated in the present invention herein, the singular forms “a”, “an” and “the” specifically, also encompass the plural forms of the terms to which they refer, unless the content clearly dictates otherwise. The term “about” is used herein to means approximately, in the region of, roughly, or around.

As stated herein, that it follows in a transitional phrase or in the body of a claim, the terms “comprise(s)” and “comprising” are to be interpreted as having an open-ended meaning. That is, the terms are to be interpreted synonymously with the phrases “having at least” or “including at least”.

As used herein, the terms "pesticide effect" and "pesticide activity" mean any direct or indirect action on the target pest that results in reduced feeding damage on the seeds, roots, shoots and foliage of plants as a result of application of said formulation.

The main embodiment of the present invention is to provide stable Suspo-Emulsion (SE) formulation of Flonicamid and Bifenthrin which is effective against crop pests and is safe and stable.

In various embodiments the present invention provides pesticide composition of Flonicamid and Bifenthrin.

As per one embodiment, the present invention is to provide a pesticide Suspo-Emulsion formulation of Flonicamid and Bifenthrin with one or more inactive ingredients.

Another embodiment of the present invention, provides a Suspo-Emulsion pesticidal formulation comprising:
a) Flonicamid in the concentration range of 20-30% w/w.
b) Bifenthrin in the concentration range of 5-15% w/w.
c) One or more dispersing agent in the concentration range of 0.5-5% w/w.
d) One or more wetting agent in the concentration range of 0.5-4% w/w
e) One or more suspending agent in the concentration range of 0.5-2% w/w
f) One or more emulsifier in the concentration range of 2-5% w/w
g) One or more adjuvant in the concentration range of 0.05-5% w/w
h) Solvent in the concentration range of 8-15% w/w.

Active ingredient is the actual chemical in the product mixture that controls the pests. Active ingredient plays a key role in the functioning of the product mixture.

As per one embodiment, the active ingredient for the present invention is Flonicamid and Bifenthrin, wherein Flonicamid is in the range of 20-30 %w/w and Bifenthrin is in the range of 5-15 %w/w in Suspo-Emulsion (SE) formulation.

The dispersing agent is a substance, that is added to a suspension of solid or liquid particles in a liquid (such as a colloid or emulsion) to improve the separation of the particles and to prevent their settling or clumping. A dispersing agent is a substance which adsorbs onto the surface of a particles and helps to preserve the state of dispersion of the particles and prevents them from reaggregating. Dispersing agents are added to agrochemical formulations to facilitate dispersion and suspension during manufacture, and to ensure the particles redisperse into vehicle or carrier.

As per one embodiment, dispersing agent for the Suspo-Emulsion formulation of the present invention is selected from group consisting of modified styrene Acrylic polymer, Ethoxylated Tri-styryl phenol, sodium salt of naphthalene sulfonate formaldehyde condensates and graft copolymers or combination thereof in the concentration range of 0.5- 5% w/w.

Wetting agents/ surfactants are chemical agents which lower the surface tension of liquid by a considerable amount in order to allow it to spread upon the penetrating surface. It is well within the competence of those skilled in the art to determine whether a particular surface active agent (surfactant) is a wetting agent or not.

As per one embodiment, wetting agent for present invention is selected from group consisting of Trisiloxane ethoxylate, ethoxylated fatty alcohol, polydimethyl siloxane or combination thereof in the concentration range of 0.5-4% w/w.

Emulsifier is a chemical that aids in suspending one liquid into another. Emulsifier is a surface-active agent promoting the formation and stabilization of the product mixture.

As per one embodiment, the emulsifier for the present invention is selected from the group of non-ionic emulsifiers such as Ethoxylated tri-styryl phenols in the concentration range of 2-5% w/w.

The Suspending agent helps active agent stay suspended in the formulation and prevent sedimentation at the bottom of the container. The suspending agent helps formulation to remain stable without problem of sedimentation.

As per one embodiment, suspending agent for the present invention is selected from group consisting of Silicon Dioxide, colloidal silicon dioxide or combination thereof in the concentration of 0.5-2% w/w.

An antifreeze is defined as an additive that, when added to a water-based formulation, will reduce the freezing point of the formulation.

As per one embodiment, anti-freezing agent for the present invention is selected from group consisting of monoethylene glycol, propylene glycol, polyethylene glycol and ethylene glycol in the concentration range of 3-8% w/w.

An adjuvant is an additive which is added to make the formulations more effective, that improves or enhances application, performance, safety, storage, or handling of an active ingredient.

As per one embodiment, the pesticide formulation also contains one or more additional adjuvants selected from polysaccharides, anti-foaming agent, anti-microbial agent, thickening agent, and vehicle.

In yet another embodiment of the present invention, the benefits of the synergistic pesticidal SE formulation of Flonicamid and Bifenthrin are described as follows:
1. Effective on wide range of insects and broadening the spectrum of insecticidal activity to other pests.
2. Reduction in the rate of application of the active ingredients.
3. Adequate control of the pests with the aid of the compositions according to the invention, even at a rate of application at which the individual compounds are totally ineffective.
4. Product is adapted to use for practice by farmers.
5. Cost effective
6. Stable and ready-to-use

The following examples are meant to illustrate the present invention. The examples are presented to exemplify the invention and are not to be considered as limiting the scope of invention.

EXAMPLE
Example 1: Flonicamid + Bifenthrin Suspo-Emulsion Formulation
Chemical Composition Percent (% w/w) Function
1 Flonicamid Tech. (Purity-98.00%) 26.00 Active ingredient
2 Bifenthrin Tech. (Purity - 97.00%) 10.60 Active ingredient
3 Modified styrene Acrylic polymer 3.00 Dispersing agent
4 Ethoxylated Fatty Alcohol 2.00 Surfactant
5 Ethoxylated tri-styryl phenols 3.00 Wetting agent cum Emulsifier
6 Sodium salt of naphthalene sulfonate formaldehyde condensates 0.50 Dispersing agent
7 Silicon Dioxide 0.50 Anti-cracking agent
8 Monoethylene glycol 5.00 Anti-freezing agent
9 Trisiloxane ethoxylate 2.00 Wetting agent
10 Poly di-methyl siloxane 1.00 Anti-foaming agent
11 Polysaccharide 0.10 Thickening agent
12 1,2-benzisothiazol-3-one 0.10 Biocide
13 Solvent C-IX 10.00 Solvent
14 DM Water 36.20 Carrier
Total 100.00

Example 2: Stability study of Example 1
2.1: Heat stability for 14 days at 54 degrees centigrade & cold stability 7 days at 0 degrees centigrade
Parameters Specification (in house) Initial Heat stability at 54±2 degrees centigrade Cold stability at 0±2 degrees centigrade
Flonicamid content % w/w 23.75 to 26.50 25.35 25.38 25.36
Bifenthrin content % w/w 9.50 to 10.50 10.20 10.21 10.18
Flonicamid suspensibility % mini. 80 98.72 98.65 98.70
Bifenthrin suspensibility % mini. 80 99.21 99.15 99.11
pH range (1% aq Suspension) 5.50 to 7.50 7.15 7.12 7.11
Pourability 95% min. 97.99 98.20 98.10
Specific gravity 1.05- 1.15 1.134 1.135 1.136
Viscosity at spindle no. 6220 rpm 350-800 cps 635 632 634
Particle size (micron) D50 < 3, D90 < 10 2.4, 8.5 2.2, 7.9 2.3, 8.0
Persistent foam ml (after 1 minute) max. 60 5 6 8

2.2: Room Temperature storage stability up to 12 months
Parameters Specification (in house) 1 month 6 month 12 month
Flonicamid content % w/w 23.75 to 26.50 25.39 25.38 25.4
Bifenthrin content % w/w 9.50 to 10.50 10.22 10.25 10.21
Flonicamid suspensibility % min 80 98.76 98.67 98.73
Bifenthrin suspensibility % min 80 99.18 99.11 99.12
pH range (1% aq Suspension) 5.50 to 7.50 7.07 7.04 7.06
Pourability 95% min. 97.99 98.20 98.10
Specific gravity 1.05- 1.15 1.134 1.133 1.135
Viscosity at spindle no. 6220 rpm 350-800 cps 630 637 633
Particle size (micron) D50<3, D90<10 2.2,8.4 2.5,7.8 2.4,8.3
Persistent foam ml (after 1 minute) max. 60 8 7 8

Example 3: Field Trial Studies
Field trial experiments were conducted to evaluate the efficacy of Flonicamid and Bifenthrin SE formulation in comparison to its solo applications.

The observations were recorded by counting the no. of pests before the treatment, after 7 days of treatment and after 15 days of treatment on the crops. The % percent population reduction/ control of pests was calculated by below formula:
% Population reduction/ Control = (Mean population in Untreated plot) - (Mean population in Treated Plot) X 100
(Mean population in Untreated Plot)

Example 3(a): Efficacy of Flonicamid 25% + Bifenthrin 10% SE on Cotton sucking pest whitefly (Bemisia tabaci) population control.
Location: Raichur, Karnataka, India
Season: Kharif-2021
Crop: Cotton
Date of sowing: 05/07/2021
Date of application: 04/09/2021
Treatment details Dose Pre-Treatment 7 DAT
* 15 DAT % Reduction / Control
T1 Flonicamid 25% + Bifenthrin 10% SE 275 ml/ha 17.00 10.75 10.75 34.35
T2 Flonicamid 25% + Bifenthrin 10% SE 300 ml/ha 17.50 6.00 6.50 61.83
T3 Flonicamid 25% + Bifenthrin 10% SE 325 ml/ha 16.75 5.50 6.00 64.89
T4 Acetamiprid 20% SP 100 ml/ha 16.50 9.25 9.75 41.98
T5 Flonicamid 50% WDG 150 g/ha 16.00 9.75 9.50 41.22
T6 Untreated control 16.50 16.50 16.25 ---
CV** (%) 34.31 29.61 28.60
CD*** 5% 9.98 4.96 4.87
Note: *DAT: Days After Treatment, **CV= Co-efficient of Variation, *** CD= Critical Difference
The results of the above experiment show that the SE formulation of Flonicamid 25% + Bifenthrin 10% show synergistic effect in terms of % Population reduction/ Control of whiteflies in cotton. Maximum synergism is obtained at the dosage application rate of 325 ml/ Ha with 64.89% population reduction/ control of whiteflies.

Example 3(b) Efficacy of Flonicamid 25% + Bifenthrin 10% SE on Cotton Thrips (Thrips tabaci) population control.
Location: Raichur, Karnataka, India
Season: Kharif-2021
Crop: Cotton
Date of sowing: 05/07/2021
Date of application: 04/08/2021
Treatment details Dose Pre-Treatment 7 DAT
* 15 DAT % Reduction / Control
T1 Flonicamid 25% + Bifenthrin 10% SE 275 ml/ha 11.00 8.25 9.00 31.71
T2 Flonicamid 25% + Bifenthrin 10% SE 300 ml/ha 12.25 2.00 2.25 83.17
T3 Flonicamid 25% + Bifenthrin 10% SE 325 ml/ha 11.50 1.75 2.50 83.17
T4 Acetamiprid 20% SP 100 ml/ha 12.25 8.75 10.75 22.80
T5 Flonicamid 50% WDG 150 g/ha 14.00 8.50 11.00 22.80
T6 Untreated control 13.25 12.00 13.25
CV** (%) 32.34 30.18 32.71
CD*** 5% 6.96 3.61 4.62
Note: *DAT: Days After Treatment, **CV= Co-efficient of Variation, ***CD= Critical Difference
The results of the above experiment show that the SE formulation of Flonicamid 25% + Bifenthrin 10% show synergistic effect in terms of % Population reduction/ Control of Thrips in cotton. Maximum synergism is obtained at the dosage application rate of 300 ml/ Ha with 83.17% population reduction/ control of thrips.

Example 3(c) Efficacy of Flonicamid 25% + Bifenthrin 10% SE on Cotton Leaf Hoppers (Amrasca biguttula biguttula) population control.
Location: Raichur, Karnataka, India
Season: Kharif-2021
Crop: Cotton
Date of sowing: 05/07/2021
Date of application: 13/08/2021
Treatment details Dose Pre-Treatment 7 DAT
* 15 DAT % Reduction / Control
T1 Flonicamid 25% + Bifenthrin 10% SE 275 ml/ha 13.75 7.00 7.50 46.30
T2 Flonicamid 25% + Bifenthrin 10% SE 300 ml/ha 12.75 2.25 2.25 83.33
T3 Flonicamid 25% + Bifenthrin 10% SE 325 ml/ha 14.50 2.50 2.50 81.48
T4 Acetamiprid 20% SP 100 ml/ha 12.50 8.25 8.75 37.04
T5 Flonicamid 50% WDG 150 g/ha 12.50 7.50 8.00 42.59
T6 Untreated control 13.50 13.25 13.75
CV** (%) 15.30 26.14 26.39
CD*** 5% 3.53 3.03 3.31
Note: *DAT: Days After Treatment, **CV= Co-efficient of Variation, ***CD= Critical Difference

The results of the above experiment show that the SE formulation of Flonicamid 25% + Bifenthrin 10% show synergistic effect in terms of % Population reduction/ Control of Leaf hoppers in cotton. Maximum synergism is obtained at the dosage application rate of 300 ml/ Ha with 83.33% population reduction/ control of Leaf Hoppers.

Technical advancements:
The present disclosure described herein above has several technical advantages including, but not limited to, the realization of:
• A synergistic pesticidal Suspo-emulsion formulation comprising Flonicamid and Bifenthrin;
• A synergistic pesticidal Suspo-emulsion formulation comprising Flonicamid and Bifenthrin which is stable and is in a ready to use form;

From the results in Examples 1-3, the pesticidal combination of Flonicamid and Bifenthrin in SE formulation claimed in the present invention has a synergistic effect on control of pests.

Throughout this specification, the word “comprise”, or variations such as “comprises” or “comprising”, will be understood to imply the inclusion of a stated element, integer or step, or group of elements, integers or steps, but not exclusion of any other element, integer or step, or group of elements, integers or steps.

Although the foregoing invention has been described in some way by way of illustration and example of purposes of clarity of understanding, it will be readily apparent to those of ordinary skill in the art in light of the teachings of this invention that certain changes and modifications may be made thereto.
,CLAIMS:We Claim:
1. A synergistic pesticide composition comprising:
a) Flonicamid Technical (Purity-98.00%) in the concentration range of 20-30% w/w,
b) Bifenthrin Technical (Purity-97.00%) in the concentration range of 5-15% w/w,
c) One or more Dispersing agent in the concentration range of 0.5-5% w/w,
d) One or more Wetting agent in the concentration range of 0.5-4% w/w,
e) One or more Suspending agent in the concentration range of 0.5-2% w/w,
f) One or more Emulsifier in the concentration range of 2-5% w/w,
g) One or more Adjuvant in the concentration range of 0.05-8% w/w,
h) Solvent in the concentration range of 8-15% w/w.

2. The synergistic pesticide composition as claimed in claim 1, wherein the formulation is Suspo-Emulsion (SE) formulation.

3. The synergistic pesticide composition as claimed in claim 1, wherein Flonicamid is in the range of 20-30% w/w.

4. The synergistic pesticide composition as claimed in claim 1, wherein Bifenthrin is in the range of 5-15% w/w.

5. The synergistic pesticide composition as claimed in claim 1, wherein the dispersing agent is selected from the group consisting of modified styrene Acrylic polymer, Ethoxylated Tri-styryl phenol, sodium salt of naphthalene sulfonate formaldehyde condensates and graft copolymers or combination thereof in the concentration range of 0.5- 5% w/w

6. The synergistic pesticide composition as claimed in claim 1, wherein the wetting agent is selected from the group Trisiloxane ethoxylate, ethoxylated fatty alcohol, polydimethyl siloxane or combination thereof in the concentration range of 0.5-4% w/w.

7. The synergistic pesticide composition as claimed in claim 1, wherein the suspending agent is selected from group consisting of Silicon Dioxide, colloidal silicon dioxide or combination thereof in the concentration of 0.5-2% w/w.

8. The synergistic pesticide composition as claimed in claim 1, wherein the emulsifier is selected from the group of non-ionic emulsifiers such as Ethoxylated tri-styryl phenols in the concentration range of 2-5% w/w.

9. The synergistic pesticide composition as claimed in claim 1, wherein anti-freezing agent is selected from group consisting of monoethylene glycol, propylene glycol, polyethylene glycol and ethylene glycol in the concentration range of 3-8% w/w.

10. The synergistic pesticide composition as claimed in claim 1, wherein the solvent is Solvent C-IX in the concentration range of 8-15% w/w.

Dated this 28th day of December, 2022