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Taste Masked Orally Disintegrating Composition Of Imatinib Mesylate And Process For The Preparation Thereof

Abstract: The present invention provides a taste masked orally disintegrating composition, preferably an orally disintegrating tablet of Imatinib or pharmaceutically acceptable salt thereof, comprising a) Imatinib or pharmaceutically acceptable salts thereof, b) a taste-masking polymer, c) a super disintegrant and optionally other excipients, and the process for preparing the same

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
15 April 2011
Publication Number
43/2012
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
Parent Application

Applicants

SUVEN NISHTAA PHARMA PVT LTD
SUVEN NISHTAA PHARMA PVT LTD, SERENE CHAMBERS, ROAD NO.5, AVENUE-7, BANJARA HILLS, HYDERABAD - 500 034

Inventors

1. RAVULA SAYISIVA PRASAD
SUVEN NISHTAA PHARMA PVT LTD, SERENE CHAMBERS, ROAD NO.5, AVENUE-7, BANJARA HILLS, HYDERABAD - 500 034

Specification

FIELD OF THE INVENTION The present invention relates to a taste masked orally disintegrating composition, preferably an orally disintegrating tablet of Imatinib or pharmaceutically acceptable salt thereof, comprising a) Imatinib or pharmaceutically acceptable salts thereof, b) a taste-masking polymer, c) a super disintegrant and optionally other excipients. BACKGROUND OF THE INVENTION Imatinib mesylate is chemically designated as 4-(4-methylpiperazin-l-ylmethyl)-N- [4-methyl-3-(4-pyridin-3-yl) pyrimidin-2-ylamino) phenyl]-benzamide methane sulfonate and its structural formula is Imatinib is a protein-tyrosine kinase inhibitor, especially useful in the treatment of various types of cancer and can also be used for the treatment of atherosclerosis, thrombosis, restenosis, or fibrosis. Thus Imatinib is used for the treatment of non- malignant diseases. Imatinib is usually administered orally in the form of suitable salt, e.g., in the form of Imatinib mesylate. Imatinib mesylate is a white to off white to brownish or yellow tinged crystalline powder with an unpleasant, bitter or otherwise disagreeable taste when administered orally. Imatinib mesylate is soluble in aqueous buffers

Documents

Application Documents

# Name Date
1 1314-CHE-2011 ABSTRACT 15-04-2011.pdf 2011-04-15
1 1314-CHE-2011 FORM-5 15-04-2011.pdf 2011-04-15
2 1314-CHE-2011 CLAIMS 15-04-2011.pdf 2011-04-15
2 1314-CHE-2011 FORM-3 15-04-2011.pdf 2011-04-15
3 1314-CHE-2011 CORRESPONDENCE OTHERS 15-04-2011.pdf 2011-04-15
3 1314-CHE-2011 FORM-2 15-04-2011.pdf 2011-04-15
4 1314-CHE-2011 DESCRIPTION (COMPLETE) 15-04-2011.pdf 2011-04-15
4 1314-CHE-2011 FORM-1 15-04-2011.pdf 2011-04-15
5 1314-CHE-2011 DESCRIPTION (COMPLETE) 15-04-2011.pdf 2011-04-15
5 1314-CHE-2011 FORM-1 15-04-2011.pdf 2011-04-15
6 1314-CHE-2011 CORRESPONDENCE OTHERS 15-04-2011.pdf 2011-04-15
6 1314-CHE-2011 FORM-2 15-04-2011.pdf 2011-04-15
7 1314-CHE-2011 CLAIMS 15-04-2011.pdf 2011-04-15
7 1314-CHE-2011 FORM-3 15-04-2011.pdf 2011-04-15
8 1314-CHE-2011 ABSTRACT 15-04-2011.pdf 2011-04-15
8 1314-CHE-2011 FORM-5 15-04-2011.pdf 2011-04-15