The Process For Manufacturing Of Clear Liquid Pharmaceutical

The Process For Manufacturing Of Clear Liquid Pharmaceutical Composition Of Azithromycin

Abstract: THE PROCESS FOR MANUFACTURING OF CLEAR LIQUID PHARMACEUTICAL COMPOSITION OF AZITHROMYCIN Azithromycin is a macrolide antibiotic used for treating infection. This is available also for treating severe infection by intravenous administration of the drug. Currently it is not possible to manufacturing liquid preparation which is ready to use. As it is not soluble in water or other known solvents, for this purpose, it is being marketed as lyophilized preparation which is reconstituted prior ti use According to present invention, it is found that it is souble in water at pH 5.0. The change in pH can be obtained by adding citric acid in a desired concentration However, this solution is not stable, and precipitates are seen over the time According to present invention, this solution is stabilized by addition of sodium salts like sodium hydroxide, thereby changing its pH from 5.0 to 7.0 The solution so prepared remains clear and is stable for a longer period.

Patent Information

Application #

Filing Date

24 July 2000

Publication Number

09/2006

Publication Type

INA

Invention Field

PHARMACEUTICALS

Status

Email

Parent Application

Applicants

CADILA PHARMACEUTICALS LIMITED

IRM HOUSE, OFF C.G. ROAD, NAVRANGPURA, AHMEDABAD 380009

Inventors

1. SRIDHAR KRHNAMURTHY GUMUDAVELLI

CADILA PHARMACEUTICALS LIMITED IRM HOUSE, OFF C.G. ROAD, NAVRANGPURA, AHMEDABAD 380009

2. BAKULESH MAFATALA KHAMAR

201 ASHADHA VASUNDHARA COLONY, GULBAI TEKRA ELLISBRIDGE AHMEDABAD 380006

Specification

Documents

Application Documents

#	Name	Date
1	687-mum-2000-abstract(24-7-2001).pdf	2018-08-08
1	687-mum-2000-form 5(24-7-2001).pdf	2018-08-08
2	687-mum-2000-form 3(24-7-2000).pdf	2018-08-08
2	687-mum-2000-claims(24-7-2001).pdf	2018-08-08
3	687-mum-2000-form 2(title page)-(provisional)-(24-7-2000).pdf	2018-08-08
3	687-mum-2000-correspondence(24-7-2001).pdf	2018-08-08
4	687-mum-2000-correspondence(ipo)-(8-5-2003).pdf	2018-08-08
4	687-mum-2000-form 2(title page)-(complete)-(24-7-2001).pdf	2018-08-08
5	687-mum-2000-form 2(provisional)-(24-7-2000).pdf	2018-08-08
5	687-mum-2000-description(complete)-(24-7-2001).pdf	2018-08-08
6	687-mum-2000-form 2(complete)-(24-7-2001).pdf	2018-08-08
6	687-mum-2000-description(provisional)-(24-7-2000).pdf	2018-08-08
7	687-mum-2000-form 1(24-7-2001).pdf	2018-08-08
7	687-mum-2000-form 1(24-7-2000).pdf	2018-08-08
8	687-mum-2000-form 1(24-7-2001).pdf	2018-08-08
8	687-mum-2000-form 1(24-7-2000).pdf	2018-08-08
9	687-mum-2000-form 2(complete)-(24-7-2001).pdf	2018-08-08
9	687-mum-2000-description(provisional)-(24-7-2000).pdf	2018-08-08
10	687-mum-2000-description(complete)-(24-7-2001).pdf	2018-08-08
10	687-mum-2000-form 2(provisional)-(24-7-2000).pdf	2018-08-08
11	687-mum-2000-correspondence(ipo)-(8-5-2003).pdf	2018-08-08
11	687-mum-2000-form 2(title page)-(complete)-(24-7-2001).pdf	2018-08-08
12	687-mum-2000-form 2(title page)-(provisional)-(24-7-2000).pdf	2018-08-08
12	687-mum-2000-correspondence(24-7-2001).pdf	2018-08-08
13	687-mum-2000-form 3(24-7-2000).pdf	2018-08-08
13	687-mum-2000-claims(24-7-2001).pdf	2018-08-08
14	687-mum-2000-form 5(24-7-2001).pdf	2018-08-08
14	687-mum-2000-abstract(24-7-2001).pdf	2018-08-08