The Process For Preparing A Stable And Palatable Pharmaceutical

The Process For Preparing A Stable And Palatable Pharmaceutical Composition Fat Soluble Vitamins With Vitamin C.

Abstract: THE PROCESS FOR PREPARING A STABLE AND PALATABLE PHARMACEUTICAL COMPOSITION FAT SOLUBLE VITAMINS WITH VITAMIN C. Fat soluble vitamins like vitamin E is used along with vitamin C for many therapeutic indications. Vitamin E also has an unpleasant taste. For this reason it is supplied in soft gelatin capsules. It is not possible to formulate a stable and palatable liquid pharmaceutical composition consisting of fat soluble vitamins like Vitamin E and vitamin C. According to present invention, a process for manufacturing stable fixed dose composition containing fat soluble vitamins like Vitamin E and Vitamin C is described. According to present invetion, process of manufacturing the said composition involves preparing a solution of fat soluble vitamin in a combination involves preparing a solution of fat souble vitamin in a combination of done hydrophilic surfactant and self emulsifiying agents such as polysorbate and glycerol monosterate respectively. To this, vitamin C along with suitable stabilizers such as disodium EDTA, sodium bicarbonate is added. The formulation so prepared is found to be stable for its shelf life and also as per accelerated stability studies.

Patent Information

Application #

Filing Date

24 July 2000

Publication Number

24/2005

Publication Type

INA

Invention Field

PHARMACEUTICALS

Status

Email

Parent Application

Applicants

CADILA PHARMACEUTICALS LIMITED

IRM HOUSE, OFF C.G. ROAD, NAVRANGPURA, AHMEDABAD 380009

Inventors

1. SRIDHAR KRHNAMURTHY GUMUDAVELLI

CADILA PHARMACEUTICALS LIMITED IRM HOUSE, OFF C.G. ROAD, NAVRANGPURA, AHMEDABAD 380009

2. BAKULESH MAFATALA KHAMAR

201 ASHADHA VASUNDHARA COLONY, GULBAI TEKRA ELLISBRIDGE AHMEDABAD 380006

Specification

Documents

Application Documents

#	Name	Date
1	686-mum-2000-abstract(25-7-2001).pdf	2018-08-08
1	686-mum-2000-form 5(25-7-2001).pdf	2018-08-08
2	686-mum-2000-claims(25-7-2001).pdf	2018-08-08
2	686-mum-2000-form 3(24-7-2000).pdf	2018-08-08
3	686-mum-2000-form 2(title page)-(25-7-2001).pdf	2018-08-08
3	686-mum-2000-correspondence(25-7-2001).pdf	2018-08-08
4	686-mum-2000-form 2(complete)-(25-7-2001).pdf	2018-08-08
4	686-mum-2000-correspondence(ipo)-(8-5-2003).pdf	2018-08-08
5	686-mum-2000-description(complete)-(25-7-2001).pdf	2018-08-08
5	686-mum-2000-form 1(25-7-2001).pdf	2018-08-08
6	686-mum-2000-form 1(24-7-2000).pdf	2018-08-08
7	686-mum-2000-description(complete)-(25-7-2001).pdf	2018-08-08
7	686-mum-2000-form 1(25-7-2001).pdf	2018-08-08
8	686-mum-2000-correspondence(ipo)-(8-5-2003).pdf	2018-08-08
8	686-mum-2000-form 2(complete)-(25-7-2001).pdf	2018-08-08
9	686-mum-2000-correspondence(25-7-2001).pdf	2018-08-08
9	686-mum-2000-form 2(title page)-(25-7-2001).pdf	2018-08-08
10	686-mum-2000-form 3(24-7-2000).pdf	2018-08-08
10	686-mum-2000-claims(25-7-2001).pdf	2018-08-08
11	686-mum-2000-form 5(25-7-2001).pdf	2018-08-08
11	686-mum-2000-abstract(25-7-2001).pdf	2018-08-08