Therapeutic Composition For Osteoarthritis

Abstract: [0031] The present invention relates to a composition comprising EGCG in which EGCG acts on interleukin 1 beta inducing expression of protein associated with osteoarthritis in human chondrocytes. Along with this EGCG additionally promotes fat oxidation and thereby resolves obesity which is one of the major causes of osteoarthritis.

Patent Information

Application #

Filing Date

03 July 2012

Publication Number

30/2016

Publication Type

INA

Invention Field

PHARMACEUTICALS

Status

Email

Parent Application

Applicants

NUTRI SYNAPZZ THERAPEUTIX PRIVATE LIMITED

NO 203, 2ND FLOOR, BEML. IV THE STAGE, RAJA RAJESHWARI NAGAR, BANGALORE 560 098

Inventors

1. SRIKANTAN NIRANJAN

C/O NUTRI SYNAPZZ THERAPEUTIX PRIVATE LIMITED, NO 203, 2ND FLOOR, BEML. IV TH STAGE, RAJA RAJESHWARI NAGAR, BANGALORE 560 098

Specification

DESC:as attached ,CLAIMS:What is claimed is
1. A composition for treating osteoarthritis, the composition comprising:
a therapeutically effective amount of Epigallocatechin Gallate (EGCG) that cures the disease by suppressing interleukin 1 beta.
2. The composition according to claim 1 wherein the EGCG component of composition is extracted from green tea.
3. The composition according to claim 1 wherein the composition is in form of capsule or tablet or syrup for oral administration.
4. The composition according to claim 1 wherein the EGCG is the ester of ECGC and gallic acid.
5. The composition according to claim 1 wherein the EGCG also stimulates thermogenesis and fat oxidation, resulting in reducing obesity, which is a major co morbid factor in treating osteoarthritis.
6. The composition according to claim 1, wherein EGCG concentration in the composition is at least 90% to ensure high bioavailability.

Documents

Application Documents

#	Name	Date
1	2673-CHE-2012 POWER OF ATTORNEY 03-07-2012.pdf	2012-07-03
1	2673-CHE-2012-AbandonedLetter.pdf	2019-05-22
2	2673-CHE-2012 FORM-2 03-07-2012.pdf	2012-07-03
2	2673-CHE-2012-FER.pdf	2018-11-20
3	2673-CHE-2012 FORM-1 03-07-2012.pdf	2012-07-03
3	2673-CHE-2012 CORRESPONDENCE OTHERS 23-07-2013.pdf	2013-07-23
4	2673-CHE-2012 CORRESPONDENCE OTHERS 03-07-2012.pdf	2012-07-03
4	2673-CHE-2012 FORM-3 23-07-2013.pdf	2013-07-23
5	2673-CHE-2012 DESCRIPTION(PROVISIONAL) 03-07-2012.pdf	2012-07-03
5	Complete specification.pdf	2013-07-05
6	Form 5.pdf	2013-07-05
7	2673-CHE-2012 DESCRIPTION(PROVISIONAL) 03-07-2012.pdf	2012-07-03
7	Complete specification.pdf	2013-07-05
8	2673-CHE-2012 FORM-3 23-07-2013.pdf	2013-07-23
8	2673-CHE-2012 CORRESPONDENCE OTHERS 03-07-2012.pdf	2012-07-03
9	2673-CHE-2012 CORRESPONDENCE OTHERS 23-07-2013.pdf	2013-07-23
9	2673-CHE-2012 FORM-1 03-07-2012.pdf	2012-07-03
10	2673-CHE-2012-FER.pdf	2018-11-20
10	2673-CHE-2012 FORM-2 03-07-2012.pdf	2012-07-03
11	2673-CHE-2012-AbandonedLetter.pdf	2019-05-22
11	2673-CHE-2012 POWER OF ATTORNEY 03-07-2012.pdf	2012-07-03

Search Strategy

1	SearchStrategy_31-10-2018.pdf