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Thiazole Derivatives As Alpha 7 Nachr Modulators

Abstract: Disclosed is a compound of formula (I) wherein Y Ring D m and R R are as described herein as a modulator of nicotinic acetylcholine receptors particularly the a7 subtype in a subject in need thereof as well as pharmaceutically acceptable salts polymorphs solvates and isomers thereofs for use either alone or in combinations with suitable other medicaments and pharmaceutical compositions containing such compounds. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy particularly in the prophylaxis and therapy of disorders such as Alzheimer s disease mild cognitive impairment senile dementia and the like.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
01 September 2014
Publication Number
27/2015
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

LUPIN LIMITED
159 CST Road Kalina Santacruz (East) State of Maharashtra Mumbai 400 098 India

Inventors

1. SINHA Neelima
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
2. KARCHE Navnath Popat
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
3. HAJARE Anil Kashiram
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
4. ADURKAR Shridhar Keshav
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
5. LAIRIKYENGBAM Bikramjit Singh
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
6. RAJE Firoj Aftab
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
7. TILEKAR Ajay Ramchandra
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
8. THUBE Baban Rupaji
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
9. PALLE Venkata P.
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115
10. KAMBOJ Rajender Kumar
Lupin Limited (Research Park) 46A / 47A Nande Village Mulshi Taluka Pune 412 115

Specification

Documents

Application Documents

# Name Date
1 1756-MUMNP-2014-AbandonedLetter.pdf 2018-11-19
1 Other Document [24-08-2016(online)].pdf 2016-08-24
2 1756-MUMNP-2014-ANNEXURE TO FORM 3-130415.pdf 2018-08-11
2 Form 13 [24-08-2016(online)].pdf 2016-08-24
3 Other Patent Document [26-09-2016(online)].pdf 2016-09-26
3 1756-MUMNP-2014-CORRESPONDENCE(1-10-2014).pdf 2018-08-11
4 PCT IB 304.pdf 2018-08-11
4 1756-MUMNP-2014-Correspondence-130115.pdf 2018-08-11
5 GPA of Lupin Limited.pdf 2018-08-11
5 1756-MUMNP-2014-CORRESPONDENCE-130415.pdf 2018-08-11
6 Form-18(Online).pdf 2018-08-11
6 1756-MUMNP-2014-Correspondence-250116.pdf 2018-08-11
7 FORM 5.pdf 2018-08-11
7 1756-MUMNP-2014-FER.pdf 2018-08-11
8 FORM 3.pdf 2018-08-11
8 1756-MUMNP-2014-FORM 1(1-10-2014).pdf 2018-08-11
9 1756-MUMNP-2014-Form 3-130115.pdf 2018-08-11
9 FORM 2 & Complete Specification.pdf 2018-08-11
10 1756-MUMNP-2014-Form 3-250116.pdf 2018-08-11
10 ABSTRACT1.jpg 2018-08-11
11 1756-MUMNP-2014.pdf 2018-08-11
12 1756-MUMNP-2014-Form 3-250116.pdf 2018-08-11
12 ABSTRACT1.jpg 2018-08-11
13 1756-MUMNP-2014-Form 3-130115.pdf 2018-08-11
13 FORM 2 & Complete Specification.pdf 2018-08-11
14 1756-MUMNP-2014-FORM 1(1-10-2014).pdf 2018-08-11
14 FORM 3.pdf 2018-08-11
15 1756-MUMNP-2014-FER.pdf 2018-08-11
15 FORM 5.pdf 2018-08-11
16 1756-MUMNP-2014-Correspondence-250116.pdf 2018-08-11
16 Form-18(Online).pdf 2018-08-11
17 1756-MUMNP-2014-CORRESPONDENCE-130415.pdf 2018-08-11
17 GPA of Lupin Limited.pdf 2018-08-11
18 1756-MUMNP-2014-Correspondence-130115.pdf 2018-08-11
18 PCT IB 304.pdf 2018-08-11
19 Other Patent Document [26-09-2016(online)].pdf 2016-09-26
19 1756-MUMNP-2014-CORRESPONDENCE(1-10-2014).pdf 2018-08-11
20 Form 13 [24-08-2016(online)].pdf 2016-08-24
20 1756-MUMNP-2014-ANNEXURE TO FORM 3-130415.pdf 2018-08-11
21 Other Document [24-08-2016(online)].pdf 2016-08-24
21 1756-MUMNP-2014-AbandonedLetter.pdf 2018-11-19

Search Strategy

1 Searchstrategy_1756-MUMNP-2014_08-05-2018.pdf