Use Of Hppd Inhibitors In The Treatment Of Depression And/Or

Use Of Hppd Inhibitors In The Treatment Of Depression And/Or Withdrawal Symptoms Associated With Addictive Drugs

Abstract: ABSTRACT The present invention relates to, inter alia, the use of a compound capable of inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD) in an animal in the manufacture of a medicament for use in the treatment and/or prevention of depression. The invention also provides for the use of a compound capable of inhibiting HPPD in an animal in the manufacture of a medicament for use in the treatment of the withdrawal symptoms associated with an addictive drug which causes dopamine dependant associative learning disorders in said animal. In a particular embodiment said HPPD inhibitor is selected from the group consisting of the compound depicted as compound 1; 2; and 3.22. Figure: 1

Patent Information

Application #

Filing Date

13 February 2009

Publication Number

23/2009

Publication Type

INA

Invention Field

PHARMACEUTICALS

Status

Email

ipo@knspartners.com

Parent Application

Applicants

SYNGENTA LIMITED

European Regional Centre Priestley Road Surrey Research Park Guildford Surry GU2 7YH United Kingdom.

Inventors

1. TRAVIS Kim Zachary

CTL Alderley Park Macclesfield Cheshire SK10 4TJ United Kingdom

2. POSNER John

c/o. Syngenta Limited P.O. Box 3538 Jealott’s Hill International Research Centre Bracknell Berks RG42 6YA United Kingdom

Specification

FIELD OF THE INVENTION
The present invention relates to, inter alia, the use of a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor in the treatment of depression and/or the treatment of withdrawal symptoms associated with an addictive drug which causes dopamine dependent associative learning disorders. More specifically, the HPPD inhibitor is selected from the group consisting of: compound 1; compound 2; and compound 3.22.

Documents

Application Documents

#	Name	Date
1	839-CHENP-2009 FORM-13 16-02-2009.pdf	2009-02-16
1	839-CHENP-2009_EXAMREPORT.pdf	2016-07-02
2	839-CHENP-2009 FORM-18 13-07-2010.pdf	2010-07-13
2	Drawings.pdf	2011-09-03
3	Form-1.pdf	2011-09-03
3	Form-5.pdf	2011-09-03
4	Form-3.pdf	2011-09-03
5	Form-1.pdf	2011-09-03
5	Form-5.pdf	2011-09-03
6	839-CHENP-2009 FORM-18 13-07-2010.pdf	2010-07-13
6	Drawings.pdf	2011-09-03
7	839-CHENP-2009 FORM-13 16-02-2009.pdf	2009-02-16
7	839-CHENP-2009_EXAMREPORT.pdf	2016-07-02