The present invention describes a novel process for the production of Mycophenolate mofetil. The reaction between Mycophenolic acid with morpholino-2-ethanol in presence of reagent N,N-Carbonyl diimidazole with or without using inert organic solvents such as hydrocarbon; halogenated solvent and the like or mixtures ...

A process for the preparation of Mycophenolic acid of formula (I) comprises reacting Myphenolic acid with morpholino ethanol in presence of dipyridyl carbonate.

Process for purification of macrolides such as Tacrolimus by adsorbing crude macrolide over non ionic adsorption resin and eluting with an aqueous solvent containing cupric ions to separate process impurities. The invention covers Tacrolimus having a purity of more than 99.7%. The invention also covers preparation o...

The invention is a novel process for purification of Tacrolimus using a new polymer resin and copper salts containing cupric ions. The novel polymer resin contains polyviny1 pyrrolidone, metha acrylate diviny1 benzene based compounds. In the said process manufacturing of a new polymer resin and use of cupric salt is...

Abstract AN IMPROVED PROCESS FOR THE PREPARATION OF FIDAXOMICIN The present invention provides an improved process for the preparation of fidaxomicin by culturing Actinoplanes deccanensis in the culture medium of the invention wherein the fidaxomicin is produced in a yield of greater than 500mg/L broth. The pres...

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The present invention describes a process for isolation of romidepsin from fermentation broth and preparation of crystals of romidepsin. The process of the invention includes fewer purification steps and provides romidepsin having purity of greater than 99.5% area by HPLC. The process of the invention involves simpl...