The present invention generally relates to a therapeutic synergistic herbal composition for Neutropenia and a method for the treatment of Neutropenia using the herbal composition.

1. A novel betulinic acid derivative of formula 2: wherein R, R1, R2, R3, R4, R5 and R6 independently or in combination represent: R is H; R1 is H, Br, Cl, F or I; R2 is H and R3 is OH, OCOCH3, OCO(CH2)nCH3 where (n=l to 5), OCOq(CH3)3, OCO(CH2)n Cl (where n=l to 10), OCOC6H5, OSO2CH3, NH2/ NHCH2 CH2OH...

The invention provides a synergistic oral liquid herbal composition falling under the category of "Asavas" and "Arishtas", useful for management of diabetes, said composition comprising a therapeutically effective amount of plant extracts, self-generated ethanol to the extent of 7 to 12% v/v and having not more than...

A skin lightening topical cosmetic composition which comprises a synergistic combination of the undermentioned herbal extracts-

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The invention relates to novel carvidelol derivatives having anti-cancer activity, processes for producing such derivatives and their usefortreating or cancer of the lung, prostrate, etc.

A skin treatment synergistic composition comprising -a first composition ( daytime application product) containing one or more or a combination  of    sunscreen constituent(s)   within any known  pharmaceutically acceptable carrier, the first composition functioning to impart a protection to the skin from the harmfu...

A synergistic herbal composition useful for management of asthma, said composition comprising Solarium xanthocarpum : 3-12% w/v, Albizzia lebbeck : 5-15% w/v, Tribulus terrestris : 3-12% w/v, Glycyrrhiza glabra : 1-10% w/v, Pistachia integerrrima : 1-5% w/v, Adathoda vasica: 1-5% w/v, Woodfordia fruticosa : 1-7% w/v...

The present invention deals with a tissue culture process for producing Taxus spp. plants in vitro. The process employs use of nodal cuttings and shoot tips of mature old trees from wild as the starting material and identifies nutrient medium, culture conditions for producing Taxus plants. The procedure can be adapt...

The present invention relates to a method for reducing the levels of serum creatine kinase-MB of a patient, more specifically for Doxorubicin or Adriamycin induced increase in the levels of creatine kinase-MB which comprises administering to the patient an effective amount of 5-Methoxytryptamine or a salt thereof. ...

A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using this purified polyethoxylated castor oil enhance the...

The invention relates to the use of derivatives of cyclopentenone for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention relates more specifically to the use of derivatives of cyclopentenone for the inhibition and/or ...

The present invention deals with the development of an efficient tissue culture system for rapid development of callus cultures of Taxus sp. and Agrobacterium tumefaciens - mediated genetic transformation of callus cultures of Taxus sp. using a super binary vector, pTOK 233 (in A. tumefaciens strain LBA 4404) harbou...

A novel yeast strain having accession No DRF-UDS 004/wf and having the following characteristics: a) being sugar resistant, b) capable of producing alcohol to the extent of about 7 to llv/v% continuously and consistently in a herbal extraction medium, c) capable of overcoming resistance conferred by the herbal an...

A polypeptide for use in the treatment of cancer is disclosed. The Polypeptide has the formula (I), Pa-L-Pb-L-Pc-L-Pd, (I) where, Pa, Pb, PC, and Pd represent any of the peptides P1, P2, P3 or P4 or a pharmaceutically acceptable salt thereof; L is a linker used to link the peptides and is selected from the ...

The present invention relates to a combination of peptides that may be used for treatment of cancer. The peptide combination competes for the binding of specific neuropeptides at the plasma membrane and thereby alters the levels of key intracellular molecules implicated in cell proliferation, resulting in a broad sp...

The invention provides a novel synergistic herbal composition useful in the prevention and treatment of bone metabolic disorders, said herbal composition comprising plant parts of a calcinogenic plant together with powder of Emblica officinalis.

The present invention discloses a novel peptide of the following general formula- D-Phe-Gln-Rl-R2-Val-R3-His-R-4-NH2 wherein Rl is Trp or D-Trp R2 is Ala, Aib or Deg R3 is Gly, Aib, Deg, Dpg or Ac5c R4 is Leu or lle These novel peptides are antagonists to bombesin and bombesin like peptides are useful in the t...

Novel radiolabeled peptide analogs of vasoactive intestinal peptide with application for diagnosis and therapy in a mammalian living system are disclosed. The analogs of the present invention have excellent use as imaging and scintigraphic agents These analogs comprise of a synthetic receptor-binding peptide analo...

The present invention provides a A vasoactive intestinal peptide analog of the formula (I) His-Ser-Asp-R 1 - Val-R2-Thr-Asp-Asn-Tyr-Thr-Arg-Leu- Arg-Lys-Gin-R3 - Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NHi wherein Rl is Aib, Deg or Ac5c, R2 is Phe or 4-Cl-D-Phe, R3 is Met, Leu or Dpg wherein Aib is a-amino-iso...

PHARMACIUTICAL COMPOSITION COMPRISING BETULINICACHO AND DERIVATIVE AND METHOD OF PREPARATION THEREOF The present invention provides a pharmaceutical composition comprising from 0.1 to 40mg/ml of betulinic acid and its derivatives, from 20% to 50% by vol. of dimethylacetamide (DMA), from 20% to 40% by vol. of poly...

The invention provides novel paclitaxel derivatives obtained by effecting modifications at C2, C3 and/or C7 positions of paclitaxel, said derivatives being useful in inhibiting the growth of cancer of lung, breast, ovary, cervix or leukemia, further, the invention provides pharmaceutical compositions employing the n...

The present invention provides a novel peptide analog of Substance P of the following general formula X-D-Arg-Pro-Lys-Pro-D-Phe-Gln-D-Trp-Phe-D-Trp-Leu-R-NH2 wherein X is acetyl or straight, branched, or cyclic alkonyl group from 3-18 carbon atoms, or is deleted; R is Aib or Deg or Dpg or Ac5c or Ac6c; or a hyd...

The present invention relates to a novel herbal composition used for treating acute non A to G viral hepatitis and a process for the preparation of the composition, a method of treating acute non A to G viral hepatitis. The present novel herbal composition is derived essentially from four plants namely: (1) Phyllant...

The invention provides a method of treating a patient suffering from leukemias, lymphomas, prostate, lung or ovarian cancer employing a pharmaceutically ellective dosage of betulinic acid ; novel betulinic acid derivatives and its use for treating cancers, and a composition comprising pharmaceutical acceptable addit...

The invention provides a novel polyherbal composition useful for treating acute Hepatitis E virus infection including acute liver failure due to HEV infection, healthy Hepatitis B virus carriers who develop superadded hepatitis E virus infection, acute hepatitis B virus infection, and animal hepadna virus, therapeut...

The invention provides a novel polyherbal composition useful for treating acute Hepatitis E virus infection including acute liver failure due to HEV infection, healthy Hepatitis B virus carriers who develop superadded hepatitis E virus infection, acute hepatitis B virus infection, and animal hepadna virus, therapeut...

A process for the preparation of a synergistic herbal composition useful for treatment of drug resistant bacterial infections comprising the steps of: a) preparing a solvent extract from a neem plant in a manner such as hereindescribed, the extract being substantially free of Azadirachtin, conta...

The present invention relates to a process for the purification of polyethoxylated castor oil or Cremophor-EL which is used as a solubilizing agent for a number of anticancer products. More precisely, the invention is directed towards a method that decreases the pH value of Cremophor-EL using clay or metal salts and...

A stabilized pharmaceutical composition of anticancer drug and a solvent like dehydrated alcohol is disclosed. Polyethoxylated castor oil (cremophor) or any other suitable solubilizer suitable for human administration may optionally be added. A method is disclosed that includes the addition of a stabilizing agent Ma...

The present invention relates to novel yeast strains bearing accession numbers DRF-UDS-004/wf, DRH-UDS-016/wf and DRF-UDS-017/wf and a method for propagation of yeast cultures comprising the steps of preparing an aqueous medium comprising 10-40% sucrose, inoculating the medium with a yeast strain and incubating the ...

The present invention relates to novel antiproliferative and anti secrectory peptides that are inhibitory to vasoactive intestinal peptide receptor and are useful in the treatment of cancer. The invention particularly relates to the synthesis of lipid-peptide conjugates containing fatty acids of different sizes, whi...

Present invention relates to a composition useful for treatment of cancer comprising an anti-cancer agent and improved polyethoxylated castor oil having low ionic content.

1. A method for preparation of herbal formulations classified as 'asavas' and 'arishtas' containing self-generated alcohol to the extent of 7 to 14%, said method comprising the steps of:a. preparing, in a known manner, a first mediumconsisting of 10 to 40 % sucrose derived from jaggery,

This invention relates to an improved process for A process for the preparation of novel synergistic pharmaceutical herbal composition for treatment of acute and chronic viral hepatitis, hepatitis E virus infection, therapeutic effect of hepatitis B virus infection and as a hepatoprotective agent, said proce...

The present invention provides a process for the preparation of 3-N-benzylidene derivative of betulinic acid, used for treatment of angiogenesis, said process comprising the steps of dissolving 3-amino derivative of betulinic acid in an alcoholic solvent to obtain a solution, adding a benzaldehyde reagent th...